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Paraneoplastic syndromes of the spinal cord, nerve, and muscle

Identifieur interne : 006B58 ( Istex/Corpus ); précédent : 006B57; suivant : 006B59

Paraneoplastic syndromes of the spinal cord, nerve, and muscle

Auteurs : Stacy A. Rudnicki ; Josep Dalmau

Source :

RBID : ISTEX:E5461FD240D73CC7BD0106F6F0D44B588C725C74

Abstract

Cancer can affect the peripheral nervous system by non‐metastatic, sometimes immune‐mediated mechanisms. Recognition of these paraneoplastic syndromes is important because it can lead to the detection of the tumor, and also helps to avoid unnecessary studies to determine the cause of the neurologic symptoms in patients with cancer. Many paraneoplastic syndromes of the peripheral nervous system are not associated with serum antibodies that serve as markers of paraneoplasia. For this group of disorders the diagnosis depends on the clinician's index of suspicion and conventional electrophysiologic and laboratory tests. Treatment of the tumor, immunotherapy, or both may improve some of these syndromes. This review focuses on paraneoplastic syndromes of the spinal cord, peripheral nerve, and muscle. © 2000 John Wiley & Sons, Inc. Muscle Nerve 23: 1800–1818, 2000

Url:
DOI: 10.1002/1097-4598(200012)23:12<1800::AID-MUS3>3.0.CO;2-X

Links to Exploration step

ISTEX:E5461FD240D73CC7BD0106F6F0D44B588C725C74

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