Some special skin tumours in the elderly
Identifieur interne : 006888 ( Istex/Corpus ); précédent : 006887; suivant : 006889Some special skin tumours in the elderly
Auteurs : E. Wilson JonesSource :
- British Journal of Dermatology [ 0007-0963 ] ; 1990-04.
Abstract
A review of uncommon skin tumours, all of which characteristically arise in elderly patients, is presented. Angiosarcoma of the face and scalp is a highly progressive tumour with a poor prognosis, but initially it may be misdiagnosed as a simple bruise or cellulitis. In well‐differentiated tumours a characteristic feature is interlacing endothelial cell‐lined channels showing considerable nuclear atypia. Merkel cell tumours, which develop as deep‐seated nodules in the skin, occur most frequently in photodamaged areas, especially on the head and neck. The prognosis of Merkel cell tumours is generally poor; histological evidence suggests that some of these tumours may be a special type of poorly differentiated squamous cell carcinoma. Atypical fibroxanthoma, which is normally benign, occurs most frequently in elderly, fair‐skirmed males, especially around the face. It is typically a polypoid lesion with a vascular appearance. Acantholytic squamous cell carcinomas, also known as adenoid squamous cell carcinomas, are most common in fair‐skinned men with a history of keratoses. They also occur in the female genital region and the oral mucosa. Histologically, these tumours differ from squamous cell carcinomas because of their tendency to form duct‐like areas in tumour lobules.
Url:
DOI: 10.1111/j.1365-2133.1990.tb16128.x
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Wilson Jones, Department of Histopathology, Institute of Dermatology, 5 Lisle Street, London WC2H 7BJ, U.K.</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:DF905487E5543F71D9CD503ED9FB4ED690E32A43</idno><date when="1990" year="1990">1990</date><idno type="doi">10.1111/j.1365-2133.1990.tb16128.x</idno><idno type="url">https://api.istex.fr/document/DF905487E5543F71D9CD503ED9FB4ED690E32A43/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">006888</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">006888</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Some special skin tumours in the elderly</title><author><name sortKey="Jones, E Wilson" sort="Jones, E Wilson" uniqKey="Jones E" first="E. Wilson" last="Jones">E. Wilson Jones</name><affiliation><mods:affiliation>Department of Histopathology, Institute of Dermatology, University of London, London, U.K.</mods:affiliation></affiliation><affiliation><mods:affiliation>Professor E. Wilson Jones, Department of Histopathology, Institute of Dermatology, 5 Lisle Street, London WC2H 7BJ, U.K.</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">British Journal of Dermatology</title><title level="j" type="alt">BRITISH JOURNAL OF DERMATOLOGY</title><idno type="ISSN">0007-0963</idno><idno type="eISSN">1365-2133</idno><imprint><biblScope unit="vol">122</biblScope><biblScope unit="page" from="71">71</biblScope><biblScope unit="page" to="75">75</biblScope><biblScope unit="page-count">5</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1990-04">1990-04</date></imprint><idno type="ISSN">0007-0963</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0007-0963</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A review of uncommon skin tumours, all of which characteristically arise in elderly patients, is presented. Angiosarcoma of the face and scalp is a highly progressive tumour with a poor prognosis, but initially it may be misdiagnosed as a simple bruise or cellulitis. In well‐differentiated tumours a characteristic feature is interlacing endothelial cell‐lined channels showing considerable nuclear atypia. Merkel cell tumours, which develop as deep‐seated nodules in the skin, occur most frequently in photodamaged areas, especially on the head and neck. The prognosis of Merkel cell tumours is generally poor; histological evidence suggests that some of these tumours may be a special type of poorly differentiated squamous cell carcinoma. Atypical fibroxanthoma, which is normally benign, occurs most frequently in elderly, fair‐skirmed males, especially around the face. It is typically a polypoid lesion with a vascular appearance. Acantholytic squamous cell carcinomas, also known as adenoid squamous cell carcinomas, are most common in fair‐skinned men with a history of keratoses. 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WILSON</forename><surname>JONES</surname></persName><affiliation>Department of Histopathology, Institute of Dermatology, University of London, London, U.K.</affiliation><affiliation>Professor E. 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WILSON</givenNames><familyName>JONES</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="a1"><unparsedAffiliation>Department of Histopathology, Institute of Dermatology, University of London, London, U.K.</unparsedAffiliation></affiliation></affiliationGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">SUMMARY</title><p>A review of uncommon skin tumours, all of which characteristically arise in elderly patients, is presented. Angiosarcoma of the face and scalp is a highly progressive tumour with a poor prognosis, but initially it may be misdiagnosed as a simple bruise or cellulitis. In well‐differentiated tumours a characteristic feature is interlacing endothelial cell‐lined channels showing considerable nuclear atypia. Merkel cell tumours, which develop as deep‐seated nodules in the skin, occur most frequently in photodamaged areas, especially on the head and neck. The prognosis of Merkel cell tumours is generally poor; histological evidence suggests that some of these tumours may be a special type of poorly differentiated squamous cell carcinoma. Atypical fibroxanthoma, which is normally benign, occurs most frequently in elderly, fair‐skirmed males, especially around the face. It is typically a polypoid lesion with a vascular appearance. Acantholytic squamous cell carcinomas, also known as adenoid squamous cell carcinomas, are most common in fair‐skinned men with a history of keratoses. They also occur in the female genital region and the oral mucosa. 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Wilson Jones, Department of Histopathology, Institute of Dermatology, 5 Lisle Street, London WC2H 7BJ, U.K.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">1990-04</dateIssued><copyrightDate encoding="w3cdtf">1990</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="references">17</extent></physicalDescription><abstract lang="en">A review of uncommon skin tumours, all of which characteristically arise in elderly patients, is presented. Angiosarcoma of the face and scalp is a highly progressive tumour with a poor prognosis, but initially it may be misdiagnosed as a simple bruise or cellulitis. In well‐differentiated tumours a characteristic feature is interlacing endothelial cell‐lined channels showing considerable nuclear atypia. Merkel cell tumours, which develop as deep‐seated nodules in the skin, occur most frequently in photodamaged areas, especially on the head and neck. The prognosis of Merkel cell tumours is generally poor; histological evidence suggests that some of these tumours may be a special type of poorly differentiated squamous cell carcinoma. Atypical fibroxanthoma, which is normally benign, occurs most frequently in elderly, fair‐skirmed males, especially around the face. It is typically a polypoid lesion with a vascular appearance. Acantholytic squamous cell carcinomas, also known as adenoid squamous cell carcinomas, are most common in fair‐skinned men with a history of keratoses. They also occur in the female genital region and the oral mucosa. 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