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Experimental Epinephrinogenic Pneumopathy

Identifieur interne : 005F83 ( Istex/Corpus ); précédent : 005F82; suivant : 005F84

Experimental Epinephrinogenic Pneumopathy

Source :

Beitrage zur Pathologie: "Aschoff's" Journal [ 0005-8165 ] ; 1973.

RBID : ISTEX:CC483827545791EE286E7727F20FCFBB813D431E

Abstract

Summary: The pathological changes in the lungs of rats following long-term intravenous injections (tail-vein) of epinephrine are related. The results clearly show that, under the conditions employed, epinephrine can produce massive pulmonary lesions closely resembling human pulmonary hemosiderosis. The histopathological findings and the pharmacological properties of this drug which would contribute to the production of these lesions are discussed. It is proposed that the experimental model presented could be useful for further investigations.

Url:

https://api.istex.fr/document/CC483827545791EE286E7727F20FCFBB813D431E/fulltext/pdf

DOI: 10.1016/S0005-8165(73)80120-9

Links to Exploration step

ISTEX:CC483827545791EE286E7727F20FCFBB813D431E

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<head><ce:title>Experimental Epinephrinogenic Pneumopathy</ce:title>
<ce:author-group><ce:author><ce:given-name>Marcos A.</ce:given-name>
<ce:surname>Rossi</ce:surname>
<ce:cross-ref refid="fn1"><ce:sup>1</ce:sup>
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<ce:affiliation><ce:textfn>Department of Pathology, Medical School of Ribeirão Preto (University of São Paulo), São Paulo, Brazil</ce:textfn>
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<ce:footnote id="fn1"><ce:label>1</ce:label>
<ce:note-para>Dr. <ce:small-caps>Marcos</ce:small-caps>
 A. <ce:small-caps>Rossi</ce:small-caps>
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<ce:abstract id="ab1" xml:lang="en"><ce:section-title>Summary</ce:section-title>
<ce:abstract-sec><ce:simple-para id="SP0005">The pathological changes in the lungs of rats following long-term intravenous injections (tail-vein) of epinephrine are related. The results clearly show that, under the conditions employed, epinephrine can produce massive pulmonary lesions closely resembling human pulmonary hemosiderosis. The histopathological findings and the pharmacological properties of this drug which would contribute to the production of these lesions are discussed. It is proposed that the experimental model presented could be useful for further investigations.</ce:simple-para>
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<tail><ce:bibliography id="R0005"><ce:section-title>References</ce:section-title>
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<abstract lang="en">Summary: The pathological changes in the lungs of rats following long-term intravenous injections (tail-vein) of epinephrine are related. The results clearly show that, under the conditions employed, epinephrine can produce massive pulmonary lesions closely resembling human pulmonary hemosiderosis. The histopathological findings and the pharmacological properties of this drug which would contribute to the production of these lesions are discussed. It is proposed that the experimental model presented could be useful for further investigations.</abstract>
<abstract lang="de">Zusammenfassung: Es wird über Lungenveränderungen bei Ratten nach chronischer, intravenöser Epinephrinverabreichung berichtet. Die Veränderungen sind denen der menschlichen Lungenhämosiderose außerordentlich ähnlich. Die pathogenetisch in Frage kommenden Wirkungsmechanismen werden besprochen; das experimentelle Modell eignet sich gut für weitere Untersuchungen, die zur endgültigen Klärung der Befunde erforderlich sind.</abstract>
<relatedItem type="host"><titleInfo><title>Beitrage zur Pathologie: "Aschoff's" Journal</title>
</titleInfo>
<titleInfo type="abbreviated"><title>BPAJ</title>
</titleInfo>
<genre type="journal">journal</genre>
<originInfo><dateIssued encoding="w3cdtf">197305</dateIssued>
</originInfo>
<identifier type="ISSN">0005-8165</identifier>
<identifier type="PII">S0005-8165(73)X8119-7</identifier>
<part><date>197305</date>
<detail type="volume"><number>149</number>
<caption>vol.</caption>
</detail>
<detail type="issue"><number>1</number>
<caption>no.</caption>
</detail>
<extent unit="issue pages"><start>1</start>
<end>102</end>
</extent>
<extent unit="pages"><start>1</start>
<end>12</end>
</extent>
</part>
</relatedItem>
<identifier type="istex">CC483827545791EE286E7727F20FCFBB813D431E</identifier>
<identifier type="DOI">10.1016/S0005-8165(73)80120-9</identifier>
<identifier type="PII">S0005-8165(73)80120-9</identifier>
<identifier type="ArticleID">80120</identifier>
<accessCondition type="use and reproduction" contentType="copyright">©1973 Gustav Fischer Verlag, Stuttgart</accessCondition>
<recordInfo><recordContentSource>ELSEVIER</recordContentSource>
<recordOrigin>Gustav Fischer Verlag, Stuttgart, ©1973</recordOrigin>
</recordInfo>
</mods>
</metadata>
<serie></serie>
</istex>
</record>

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Experimental Epinephrinogenic Pneumopathy

Experimental Epinephrinogenic Pneumopathy

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