P‐58 Three cases of pathological dermal deposits associated with internal diseases in dogs (xanthomatosis, calcinosis and amyloidosis)
Identifieur interne : 005E70 ( Istex/Corpus ); précédent : 005E69; suivant : 005E71P‐58 Three cases of pathological dermal deposits associated with internal diseases in dogs (xanthomatosis, calcinosis and amyloidosis)
Auteurs : A. Muller ; E. Guaguere ; F. Degorce-RubialesSource :
- Veterinary Dermatology [ 0959-4493 ] ; 2004-08.
Abstract
Pathological dermal deposits include amyloidosis, calcinosis, mucinosis and xanthomatosis, and are especially rare in dogs. We observed three cases associated with internal diseases. The first case was a cutaneous xanthomatosis associated with pancreatitis in a 10‐year‐old poodle. Abdominal pain, vomiting and hemorrhagic diarrhoea were observed in addition to yellowish papules on the abdomen. Skin biopsies showed a granulomatous inflammation with foamy macrophages. Pancreatitis was confirmed by increased serum levels of amylase and lipase and by ultrasonography. In spite of intensive care, death occurred 12 h after admission. The second case was a cutaneous calcinosis associated with multiple congenital urinary malformations in a 6‐month‐old Brittany spaniel (metastatic calcinosis). Retarded growth and pale mucosae were present with erythematous erosive and ulcerated papules and plaques on the face, abdomen and limbs. Histopathological examination of skin biopsies showed a macrophagic granulomatous reaction around calcium deposits. Blood work revealed anaemia, uraemia, elevated creatinine, hyperphosphatemia and hypercalcaemia. Cystography demonstrated a patent urachus. The dog was euthanized and necropsy revealed bilateral hydronephrosis, nephrocalcinosis, megaureters, a patent urachus and calcified bladder. The third case was a cutaneous and systemic amyloidosis in a 5‐year‐old Siberian husky. Dermal papules, purpuric macules, ulcers and cutaneous fragility were present on the trunk. Histopathological examination of skin biopsies showed multiple dermal accumulations of amorphous eosinophilic material, which was congophilic and gave a characteristic green birefringence under polarized light. The owner refused treatment. The dog died one year later of pulmonary thrombosis and renal failure (renal amyloidosis). Funding: Self‐funded.
Url:
DOI: 10.1111/j.1365-3164.2004.00414_58.x
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ISTEX:CA0F53B73350CF8AD3E1D42DDC181B3EAAB9B452Le document en format XML
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Three cases of pathological dermal deposits associated with internal diseases in dogs (xanthomatosis, calcinosis and amyloidosis)</title><author><name sortKey="Muller, A" sort="Muller, A" uniqKey="Muller A" first="A." last="Muller">A. Muller</name><affiliation><mods:affiliation>Clinique Vétérinaire Saint‐Bernard, Lomme, France; Laboratoire d’Anatomie Pathologique Vétérinaire du Sud‐ouest, Toulouse, France</mods:affiliation></affiliation></author><author><name sortKey="Guaguere, E" sort="Guaguere, E" uniqKey="Guaguere E" first="E." last="Guaguere">E. Guaguere</name><affiliation><mods:affiliation>Clinique Vétérinaire Saint‐Bernard, Lomme, France; Laboratoire d’Anatomie Pathologique Vétérinaire du Sud‐ouest, Toulouse, France</mods:affiliation></affiliation></author><author><name sortKey="Degorce Ubiales, F" sort="Degorce Ubiales, F" uniqKey="Degorce Ubiales F" first="F." last="Degorce-Rubiales">F. Degorce-Rubiales</name><affiliation><mods:affiliation>Clinique Vétérinaire Saint‐Bernard, Lomme, France; Laboratoire d’Anatomie Pathologique Vétérinaire du Sud‐ouest, Toulouse, France</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Veterinary Dermatology</title><title level="j" type="alt">VETERINARY DERMATOLOGY</title><idno type="ISSN">0959-4493</idno><idno type="eISSN">1365-3164</idno><imprint><biblScope unit="vol">15</biblScope><biblScope unit="page" from="59">59</biblScope><biblScope unit="page" to="59">59</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2004-08">2004-08</date></imprint><idno type="ISSN">0959-4493</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0959-4493</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Pathological dermal deposits include amyloidosis, calcinosis, mucinosis and xanthomatosis, and are especially rare in dogs. We observed three cases associated with internal diseases. The first case was a cutaneous xanthomatosis associated with pancreatitis in a 10‐year‐old poodle. Abdominal pain, vomiting and hemorrhagic diarrhoea were observed in addition to yellowish papules on the abdomen. Skin biopsies showed a granulomatous inflammation with foamy macrophages. Pancreatitis was confirmed by increased serum levels of amylase and lipase and by ultrasonography. In spite of intensive care, death occurred 12 h after admission. The second case was a cutaneous calcinosis associated with multiple congenital urinary malformations in a 6‐month‐old Brittany spaniel (metastatic calcinosis). Retarded growth and pale mucosae were present with erythematous erosive and ulcerated papules and plaques on the face, abdomen and limbs. Histopathological examination of skin biopsies showed a macrophagic granulomatous reaction around calcium deposits. Blood work revealed anaemia, uraemia, elevated creatinine, hyperphosphatemia and hypercalcaemia. Cystography demonstrated a patent urachus. The dog was euthanized and necropsy revealed bilateral hydronephrosis, nephrocalcinosis, megaureters, a patent urachus and calcified bladder. The third case was a cutaneous and systemic amyloidosis in a 5‐year‐old Siberian husky. Dermal papules, purpuric macules, ulcers and cutaneous fragility were present on the trunk. Histopathological examination of skin biopsies showed multiple dermal accumulations of amorphous eosinophilic material, which was congophilic and gave a characteristic green birefringence under polarized light. The owner refused treatment. The dog died one year later of pulmonary thrombosis and renal failure (renal amyloidosis). 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Muller</name><affiliations><json:string>Clinique Vétérinaire Saint‐Bernard, Lomme, France; Laboratoire d’Anatomie Pathologique Vétérinaire du Sud‐ouest, Toulouse, France</json:string></affiliations></json:item><json:item><name>E. Guaguere</name><affiliations><json:string>Clinique Vétérinaire Saint‐Bernard, Lomme, France; Laboratoire d’Anatomie Pathologique Vétérinaire du Sud‐ouest, Toulouse, France</json:string></affiliations></json:item><json:item><name>F. Degorce‐Rubiales</name><affiliations><json:string>Clinique Vétérinaire Saint‐Bernard, Lomme, France; Laboratoire d’Anatomie Pathologique Vétérinaire du Sud‐ouest, Toulouse, France</json:string></affiliations></json:item></author><articleId><json:string>VDE414_58_58</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>abstract</json:string></originalGenre><abstract>Pathological dermal deposits include amyloidosis, calcinosis, mucinosis and xanthomatosis, and are especially rare in dogs. We observed three cases associated with internal diseases. The first case was a cutaneous xanthomatosis associated with pancreatitis in a 10‐year‐old poodle. Abdominal pain, vomiting and hemorrhagic diarrhoea were observed in addition to yellowish papules on the abdomen. Skin biopsies showed a granulomatous inflammation with foamy macrophages. Pancreatitis was confirmed by increased serum levels of amylase and lipase and by ultrasonography. In spite of intensive care, death occurred 12 h after admission. The second case was a cutaneous calcinosis associated with multiple congenital urinary malformations in a 6‐month‐old Brittany spaniel (metastatic calcinosis). Retarded growth and pale mucosae were present with erythematous erosive and ulcerated papules and plaques on the face, abdomen and limbs. Histopathological examination of skin biopsies showed a macrophagic granulomatous reaction around calcium deposits. Blood work revealed anaemia, uraemia, elevated creatinine, hyperphosphatemia and hypercalcaemia. Cystography demonstrated a patent urachus. The dog was euthanized and necropsy revealed bilateral hydronephrosis, nephrocalcinosis, megaureters, a patent urachus and calcified bladder. The third case was a cutaneous and systemic amyloidosis in a 5‐year‐old Siberian husky. Dermal papules, purpuric macules, ulcers and cutaneous fragility were present on the trunk. Histopathological examination of skin biopsies showed multiple dermal accumulations of amorphous eosinophilic material, which was congophilic and gave a characteristic green birefringence under polarized light. The owner refused treatment. The dog died one year later of pulmonary thrombosis and renal failure (renal amyloidosis). Funding: Self‐funded.</abstract><qualityIndicators><score>8.428</score><pdfVersion>1.4</pdfVersion><pdfPageSize>595 x 842 pts (A4)</pdfPageSize><refBibsNative>false</refBibsNative><abstractCharCount>1862</abstractCharCount><pdfWordCount>20170</pdfWordCount><pdfCharCount>133096</pdfCharCount><pdfPageCount>29</pdfPageCount><abstractWordCount>244</abstractWordCount></qualityIndicators><title>P‐58 Three cases of pathological dermal deposits associated with internal diseases in dogs (xanthomatosis, calcinosis and amyloidosis)</title><genre><json:string>abstract</json:string></genre><host><title>Veterinary Dermatology</title><language><json:string>unknown</json:string></language><doi><json:string>10.1111/(ISSN)1365-3164</json:string></doi><issn><json:string>0959-4493</json:string></issn><eissn><json:string>1365-3164</json:string></eissn><publisherId><json:string>VDE</json:string></publisherId><volume>15</volume><pages><first>59</first><last>59</last></pages><genre><json:string>journal</json:string></genre></host><categories><wos><json:string>science</json:string><json:string>veterinary sciences</json:string><json:string>dermatology</json:string></wos><scienceMetrix><json:string>applied sciences</json:string><json:string>agriculture, fisheries & forestry</json:string><json:string>veterinary sciences</json:string></scienceMetrix><inist><json:string>sciences appliquees, technologies et medecines</json:string><json:string>sciences biologiques et medicales</json:string><json:string>sciences medicales</json:string></inist></categories><publicationDate>2004</publicationDate><copyrightDate>2004</copyrightDate><doi><json:string>10.1111/j.1365-3164.2004.00414_58.x</json:string></doi><id>CA0F53B73350CF8AD3E1D42DDC181B3EAAB9B452</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/CA0F53B73350CF8AD3E1D42DDC181B3EAAB9B452/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/CA0F53B73350CF8AD3E1D42DDC181B3EAAB9B452/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/CA0F53B73350CF8AD3E1D42DDC181B3EAAB9B452/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main">P‐58
Three cases of pathological dermal deposits associated with internal diseases in dogs (xanthomatosis, calcinosis and amyloidosis)</title></titleStmt><publicationStmt><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2004-08"></date></publicationStmt><notesStmt><note type="content-type" subtype="abstract" source="abstract" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-HPN7T1Q2-R">abstract</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="abstract"><analytic><title level="a" type="main">P‐58
Three cases of pathological dermal deposits associated with internal diseases in dogs (xanthomatosis, calcinosis and amyloidosis)</title><title level="a" type="short">Poster Abstracts</title><author xml:id="author-0000"><persName><forename type="first">A.</forename><surname>Muller</surname></persName><affiliation>Clinique Vétérinaire Saint‐Bernard, Lomme, France; Laboratoire d’Anatomie Pathologique Vétérinaire du Sud‐ouest, Toulouse, France<address><country key="FR"></country></address></affiliation></author><author xml:id="author-0001"><persName><forename type="first">E.</forename><surname>Guaguere</surname></persName><affiliation>Clinique Vétérinaire Saint‐Bernard, Lomme, France; Laboratoire d’Anatomie Pathologique Vétérinaire du Sud‐ouest, Toulouse, France<address><country key="FR"></country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">F.</forename><surname>Degorce‐Rubiales</surname></persName><affiliation>Clinique Vétérinaire Saint‐Bernard, Lomme, France; Laboratoire d’Anatomie Pathologique Vétérinaire du Sud‐ouest, Toulouse, France<address><country key="FR"></country></address></affiliation></author><idno type="istex">CA0F53B73350CF8AD3E1D42DDC181B3EAAB9B452</idno><idno type="DOI">10.1111/j.1365-3164.2004.00414_58.x</idno><idno type="unit">VDE414_58_58</idno><idno type="toTypesetVersion">file:VDE.VDE414_58_58.pdf</idno></analytic><monogr><title level="j" type="main">Veterinary Dermatology</title><title level="j" type="alt">VETERINARY DERMATOLOGY</title><idno type="pISSN">0959-4493</idno><idno type="eISSN">1365-3164</idno><idno type="book-DOI">10.1111/(ISSN)1365-3164</idno><idno type="book-part-DOI">10.1111/vde.2004.15.issue-s1</idno><idno type="product">VDE</idno><idno type="publisherDivision">ST</idno><imprint><biblScope unit="vol">15</biblScope><biblScope unit="page" from="59">59</biblScope><biblScope unit="page" to="59">59</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2004-08"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main"><p>Pathological dermal deposits include amyloidosis, calcinosis, mucinosis and xanthomatosis, and are especially rare in dogs. We observed three cases associated with internal diseases. The first case was a cutaneous xanthomatosis associated with pancreatitis in a 10‐year‐old poodle. Abdominal pain, vomiting and hemorrhagic diarrhoea were observed in addition to yellowish papules on the abdomen. Skin biopsies showed a granulomatous inflammation with foamy macrophages. Pancreatitis was confirmed by increased serum levels of amylase and lipase and by ultrasonography. In spite of intensive care, death occurred 12 h after admission. The second case was a cutaneous calcinosis associated with multiple congenital urinary malformations in a 6‐month‐old Brittany spaniel (metastatic calcinosis). Retarded growth and pale mucosae were present with erythematous erosive and ulcerated papules and plaques on the face, abdomen and limbs. Histopathological examination of skin biopsies showed a macrophagic granulomatous reaction around calcium deposits. Blood work revealed anaemia, uraemia, elevated creatinine, hyperphosphatemia and hypercalcaemia. Cystography demonstrated a patent urachus. The dog was euthanized and necropsy revealed bilateral hydronephrosis, nephrocalcinosis, megaureters, a patent urachus and calcified bladder. The third case was a cutaneous and systemic amyloidosis in a 5‐year‐old Siberian husky. Dermal papules, purpuric macules, ulcers and cutaneous fragility were present on the trunk. Histopathological examination of skin biopsies showed multiple dermal accumulations of amorphous eosinophilic material, which was congophilic and gave a characteristic green birefringence under polarized light. The owner refused treatment. The dog died one year later of pulmonary thrombosis and renal failure (renal amyloidosis).</p><p>
<hi rend="italic">Funding: Self‐funded.</hi>
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Three cases of pathological dermal deposits associated with internal diseases in dogs (xanthomatosis, calcinosis and amyloidosis)</title><title type="short">Poster Abstracts</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#aff-1-1"><personName><givenNames>A.</givenNames><familyName>Muller</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#aff-1-1"><personName><givenNames>E.</givenNames><familyName>Guaguere</familyName></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#aff-1-1"><personName><givenNames>F.</givenNames><familyName>Degorce‐Rubiales</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="aff-1-1" countryCode="FR"><unparsedAffiliation>Clinique Vétérinaire Saint‐Bernard, Lomme, France; Laboratoire d’Anatomie Pathologique Vétérinaire du Sud‐ouest, Toulouse, France</unparsedAffiliation></affiliation></affiliationGroup><abstractGroup><abstract type="main" xml:lang="en"><p>Pathological dermal deposits include amyloidosis, calcinosis, mucinosis and xanthomatosis, and are especially rare in dogs. We observed three cases associated with internal diseases. The first case was a cutaneous xanthomatosis associated with pancreatitis in a 10‐year‐old poodle. Abdominal pain, vomiting and hemorrhagic diarrhoea were observed in addition to yellowish papules on the abdomen. Skin biopsies showed a granulomatous inflammation with foamy macrophages. Pancreatitis was confirmed by increased serum levels of amylase and lipase and by ultrasonography. In spite of intensive care, death occurred 12 h after admission. The second case was a cutaneous calcinosis associated with multiple congenital urinary malformations in a 6‐month‐old Brittany spaniel (metastatic calcinosis). Retarded growth and pale mucosae were present with erythematous erosive and ulcerated papules and plaques on the face, abdomen and limbs. Histopathological examination of skin biopsies showed a macrophagic granulomatous reaction around calcium deposits. Blood work revealed anaemia, uraemia, elevated creatinine, hyperphosphatemia and hypercalcaemia. Cystography demonstrated a patent urachus. The dog was euthanized and necropsy revealed bilateral hydronephrosis, nephrocalcinosis, megaureters, a patent urachus and calcified bladder. The third case was a cutaneous and systemic amyloidosis in a 5‐year‐old Siberian husky. Dermal papules, purpuric macules, ulcers and cutaneous fragility were present on the trunk. Histopathological examination of skin biopsies showed multiple dermal accumulations of amorphous eosinophilic material, which was congophilic and gave a characteristic green birefringence under polarized light. The owner refused treatment. The dog died one year later of pulmonary thrombosis and renal failure (renal amyloidosis).</p><p> <i>Funding: Self‐funded.</i> </p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>P‐58 Three cases of pathological dermal deposits associated with internal diseases in dogs (xanthomatosis, calcinosis and amyloidosis)</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Poster Abstracts</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>P‐58
Three cases of pathological dermal deposits associated with internal diseases in dogs (xanthomatosis, calcinosis and amyloidosis)</title></titleInfo><name type="personal"><namePart type="given">A.</namePart><namePart type="family">Muller</namePart><affiliation>Clinique Vétérinaire Saint‐Bernard, Lomme, France; Laboratoire d’Anatomie Pathologique Vétérinaire du Sud‐ouest, Toulouse, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E.</namePart><namePart type="family">Guaguere</namePart><affiliation>Clinique Vétérinaire Saint‐Bernard, Lomme, France; Laboratoire d’Anatomie Pathologique Vétérinaire du Sud‐ouest, Toulouse, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F.</namePart><namePart type="family">Degorce‐Rubiales</namePart><affiliation>Clinique Vétérinaire Saint‐Bernard, Lomme, France; Laboratoire d’Anatomie Pathologique Vétérinaire du Sud‐ouest, Toulouse, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="abstract" displayLabel="abstract"></genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2004-08</dateIssued><copyrightDate encoding="w3cdtf">2004</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">Pathological dermal deposits include amyloidosis, calcinosis, mucinosis and xanthomatosis, and are especially rare in dogs. We observed three cases associated with internal diseases. The first case was a cutaneous xanthomatosis associated with pancreatitis in a 10‐year‐old poodle. Abdominal pain, vomiting and hemorrhagic diarrhoea were observed in addition to yellowish papules on the abdomen. Skin biopsies showed a granulomatous inflammation with foamy macrophages. Pancreatitis was confirmed by increased serum levels of amylase and lipase and by ultrasonography. In spite of intensive care, death occurred 12 h after admission. The second case was a cutaneous calcinosis associated with multiple congenital urinary malformations in a 6‐month‐old Brittany spaniel (metastatic calcinosis). Retarded growth and pale mucosae were present with erythematous erosive and ulcerated papules and plaques on the face, abdomen and limbs. Histopathological examination of skin biopsies showed a macrophagic granulomatous reaction around calcium deposits. Blood work revealed anaemia, uraemia, elevated creatinine, hyperphosphatemia and hypercalcaemia. Cystography demonstrated a patent urachus. The dog was euthanized and necropsy revealed bilateral hydronephrosis, nephrocalcinosis, megaureters, a patent urachus and calcified bladder. The third case was a cutaneous and systemic amyloidosis in a 5‐year‐old Siberian husky. Dermal papules, purpuric macules, ulcers and cutaneous fragility were present on the trunk. Histopathological examination of skin biopsies showed multiple dermal accumulations of amorphous eosinophilic material, which was congophilic and gave a characteristic green birefringence under polarized light. The owner refused treatment. The dog died one year later of pulmonary thrombosis and renal failure (renal amyloidosis). Funding: Self‐funded.</abstract><relatedItem type="host"><titleInfo><title>Veterinary Dermatology</title></titleInfo><genre type="journal">journal</genre><identifier type="ISSN">0959-4493</identifier><identifier type="eISSN">1365-3164</identifier><identifier type="DOI">10.1111/(ISSN)1365-3164</identifier><identifier type="PublisherID">VDE</identifier><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>15</number></detail><detail type="supplement"><caption>Suppl. no.</caption><number>s1</number></detail><extent unit="pages"><start>59</start><end>59</end></extent></part></relatedItem><identifier type="istex">CA0F53B73350CF8AD3E1D42DDC181B3EAAB9B452</identifier><identifier type="DOI">10.1111/j.1365-3164.2004.00414_58.x</identifier><identifier type="ArticleID">VDE414_58_58</identifier><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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