Prenatal treatment of fetal hydrops associated with the hypertelorism‐dysphagia syndrome (opitz‐g syndrome)
Identifieur interne : 005922 ( Istex/Corpus ); précédent : 005921; suivant : 005923Prenatal treatment of fetal hydrops associated with the hypertelorism‐dysphagia syndrome (opitz‐g syndrome)
Auteurs : M. A. Patton ; M. Baraitser ; K. Nickolaides ; C. H. Rodeck ; H. GamsuSource :
- Prenatal Diagnosis [ 0197-3851 ] ; 1986-03.
Abstract
Non‐immunological fetal hydrops diagnosed prenatally presents a difficult diagnostic and therapeutic problem. In the case presented, fetal hydrops was recognized at 19 weeks gestation and no specific cause was found prenatally in spite of extensive investigations. The fetal hydrops was treated in utero by thoracocentesis and an intravenous infusion of albumin carried out at fetoscopy. After birth the infant was recognized to have the hypertelorismdysphagia syndrome (or Opitz‐G syndrome, McK no. 30710). This autosomal dominant syndrome consists of hypertelorism, laryngeal abnormalities, swallowing difficulties, hyprospadias and an imperforate anus. Fetal hydrops has been reported on one previous occasion in this syndrome. The intrauterine treatment given in this case may have been successful in reducing the neonatal complications of the Opitz‐G syndrome.
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DOI: 10.1002/pd.1970060206
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Gamsu</name><affiliation><mods:affiliation>Departments of Obstetrics and Paediatrics, King's College Hospital, Denmark Hill, London SE5 8RX, U.K.</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Prenatal Diagnosis</title><title level="j" type="alt">PRENATAL DIAGNOSIS</title><idno type="ISSN">0197-3851</idno><idno type="eISSN">1097-0223</idno><imprint><biblScope unit="vol">6</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="109">109</biblScope><biblScope unit="page" to="115">115</biblScope><biblScope unit="page-count">7</biblScope><publisher>John Wiley & Sons, Ltd.</publisher><pubPlace>Chichester, UK</pubPlace><date type="published" when="1986-03">1986-03</date></imprint><idno type="ISSN">0197-3851</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0197-3851</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Non‐immunological fetal hydrops diagnosed prenatally presents a difficult diagnostic and therapeutic problem. In the case presented, fetal hydrops was recognized at 19 weeks gestation and no specific cause was found prenatally in spite of extensive investigations. The fetal hydrops was treated in utero by thoracocentesis and an intravenous infusion of albumin carried out at fetoscopy. After birth the infant was recognized to have the hypertelorismdysphagia syndrome (or Opitz‐G syndrome, McK no. 30710). This autosomal dominant syndrome consists of hypertelorism, laryngeal abnormalities, swallowing difficulties, hyprospadias and an imperforate anus. Fetal hydrops has been reported on one previous occasion in this syndrome. The intrauterine treatment given in this case may have been successful in reducing the neonatal complications of the Opitz‐G syndrome.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>hydrops</json:string><json:string>fetal</json:string><json:string>fetal hydrops</json:string><json:string>ultrasound</json:string><json:string>gestation</json:string><json:string>utero</json:string><json:string>hernia</json:string><json:string>diaphragmatic</json:string><json:string>hypoalbuminaemia</json:string><json:string>prenatal</json:string><json:string>fetalis</json:string><json:string>fetoscopy</json:string><json:string>weeks gestation</json:string><json:string>syndrome</json:string><json:string>prenatally</json:string><json:string>hypertelorism</json:string><json:string>hypoplasia</json:string><json:string>ascites</json:string><json:string>pleural effusions</json:string><json:string>effusion</json:string><json:string>fetus</json:string><json:string>pleural fluid</json:string><json:string>congenital diaphragmatic hernia</json:string><json:string>hydrops fetalis</json:string><json:string>thoracocentesis</json:string><json:string>intrauterine</json:string><json:string>anus</json:string><json:string>posteriorly</json:string><json:string>hypoplastic</json:string><json:string>congenital</json:string><json:string>ultrasound scan</json:string><json:string>plasma albumin</json:string><json:string>prenatal diagnosis</json:string><json:string>patton etal</json:string><json:string>dysmorphic features</json:string><json:string>second fetoscopy</json:string><json:string>intrauterine treatment</json:string><json:string>normal range</json:string><json:string>rhesus incompatibility</json:string><json:string>hypoplastic lungs</json:string><json:string>pleural cavities</json:string><json:string>cystic hygroma</json:string><json:string>loose skin</json:string><json:string>specific cause</json:string><json:string>adult life</json:string><json:string>imperforate anus</json:string><json:string>prenatal treatment</json:string><json:string>pulmonary hypoplasia</json:string><json:string>hypoplastic lung</json:string><json:string>hydrops foetalis</json:string><json:string>patton</json:string></teeft></keywords><author><json:item><name>M. A. Patton</name><affiliations><json:string>Department of Clinical Genetics, Institute of Child Health, 30 Guilford Street, London, WC1N1EH, U.K.</json:string></affiliations></json:item><json:item><name>M. Baraitser</name><affiliations><json:string>Department of Clinical Genetics, Institute of Child Health, 30 Guilford Street, London, WC1N1EH, U.K.</json:string></affiliations></json:item><json:item><name>K. Nickolaides</name><affiliations><json:string>Departments of Obstetrics and Paediatrics, King's College Hospital, Denmark Hill, London SE5 8RX, U.K.</json:string></affiliations></json:item><json:item><name>C. H. Rodeck</name><affiliations><json:string>Departments of Obstetrics and Paediatrics, King's College Hospital, Denmark Hill, London SE5 8RX, U.K.</json:string></affiliations></json:item><json:item><name>H. 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The fetal hydrops was treated in utero by thoracocentesis and an intravenous infusion of albumin carried out at fetoscopy. After birth the infant was recognized to have the hypertelorismdysphagia syndrome (or Opitz‐G syndrome, McK no. 30710). This autosomal dominant syndrome consists of hypertelorism, laryngeal abnormalities, swallowing difficulties, hyprospadias and an imperforate anus. Fetal hydrops has been reported on one previous occasion in this syndrome. 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A.</forename><surname>Patton</surname></persName><affiliation>Department of Clinical Genetics, Institute of Child Health, 30 Guilford Street, London, WC1N1EH, U.K.<address><country key="GB"></country></address></affiliation></author><author xml:id="author-0001"><persName><forename type="first">M.</forename><surname>Baraitser</surname></persName><affiliation>Department of Clinical Genetics, Institute of Child Health, 30 Guilford Street, London, WC1N1EH, U.K.<address><country key="GB"></country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">K.</forename><surname>Nickolaides</surname></persName><affiliation>Departments of Obstetrics and Paediatrics, King's College Hospital, Denmark Hill, London SE5 8RX, U.K.<address><country key="GB"></country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">C. 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In the case presented, fetal hydrops was recognized at 19 weeks gestation and no specific cause was found prenatally in spite of extensive investigations. The fetal hydrops was treated <hi rend="italic">in utero</hi> by thoracocentesis and an intravenous infusion of albumin carried out at fetoscopy. After birth the infant was recognized to have the hypertelorismdysphagia syndrome (or Opitz‐G syndrome, McK no. 30710). This autosomal dominant syndrome consists of hypertelorism, laryngeal abnormalities, swallowing difficulties, hyprospadias and an imperforate anus. Fetal hydrops has been reported on one previous occasion in this syndrome. 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In the case presented, fetal hydrops was recognized at 19 weeks gestation and no specific cause was found prenatally in spite of extensive investigations. The fetal hydrops was treated <i>in utero</i> by thoracocentesis and an intravenous infusion of albumin carried out at fetoscopy. After birth the infant was recognized to have the hypertelorismdysphagia syndrome (or Opitz‐G syndrome, McK no. 30710). This autosomal dominant syndrome consists of hypertelorism, laryngeal abnormalities, swallowing difficulties, hyprospadias and an imperforate anus. Fetal hydrops has been reported on one previous occasion in this syndrome. 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A.</namePart><namePart type="family">Patton</namePart><affiliation>Department of Clinical Genetics, Institute of Child Health, 30 Guilford Street, London, WC1N1EH, U.K.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Baraitser</namePart><affiliation>Department of Clinical Genetics, Institute of Child Health, 30 Guilford Street, London, WC1N1EH, U.K.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K.</namePart><namePart type="family">Nickolaides</namePart><affiliation>Departments of Obstetrics and Paediatrics, King's College Hospital, Denmark Hill, London SE5 8RX, U.K.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C. H.</namePart><namePart type="family">Rodeck</namePart><affiliation>Departments of Obstetrics and Paediatrics, King's College Hospital, Denmark Hill, London SE5 8RX, U.K.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H.</namePart><namePart type="family">Gamsu</namePart><affiliation>Departments of Obstetrics and Paediatrics, King's College Hospital, Denmark Hill, London SE5 8RX, U.K.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>John Wiley & Sons, Ltd.</publisher><place><placeTerm type="text">Chichester, UK</placeTerm></place><dateIssued encoding="w3cdtf">1986-03</dateIssued><dateCaptured encoding="w3cdtf">1985-05-20</dateCaptured><dateValid encoding="w3cdtf">1985-09-29</dateValid><copyrightDate encoding="w3cdtf">1986</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">3</extent><extent unit="references">15</extent></physicalDescription><abstract lang="en">Non‐immunological fetal hydrops diagnosed prenatally presents a difficult diagnostic and therapeutic problem. In the case presented, fetal hydrops was recognized at 19 weeks gestation and no specific cause was found prenatally in spite of extensive investigations. The fetal hydrops was treated in utero by thoracocentesis and an intravenous infusion of albumin carried out at fetoscopy. After birth the infant was recognized to have the hypertelorismdysphagia syndrome (or Opitz‐G syndrome, McK no. 30710). This autosomal dominant syndrome consists of hypertelorism, laryngeal abnormalities, swallowing difficulties, hyprospadias and an imperforate anus. Fetal hydrops has been reported on one previous occasion in this syndrome. The intrauterine treatment given in this case may have been successful in reducing the neonatal complications of the Opitz‐G syndrome.</abstract><subject lang="en"><genre>keywords</genre><topic>Fetal hydrops</topic><topic>Hypertelorism‐dysphagia syndrome Intra‐uterine treatment</topic></subject><relatedItem type="host"><titleInfo><title>Prenatal Diagnosis</title></titleInfo><titleInfo type="abbreviated"><title>Prenat. Diagn.</title></titleInfo><genre type="journal">journal</genre><subject><genre>article-category</genre><topic>Article</topic></subject><identifier type="ISSN">0197-3851</identifier><identifier type="eISSN">1097-0223</identifier><identifier type="DOI">10.1002/(ISSN)1097-0223</identifier><identifier type="PublisherID">PD</identifier><part><date>1986</date><detail type="volume"><caption>vol.</caption><number>6</number></detail><detail type="issue"><caption>no.</caption><number>2</number></detail><extent unit="pages"><start>109</start><end>115</end><total>7</total></extent></part></relatedItem><identifier type="istex">BD98DCDCF4B1C5E44CBFC066AA80E16E69B24954</identifier><identifier type="DOI">10.1002/pd.1970060206</identifier><identifier type="ArticleID">PD1970060206</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 1986 John Wiley & Sons, Ltd.</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>John Wiley & Sons, Ltd.</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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