Functional outcomes after extended surgery for gastric cancer
Identifieur interne : 005391 ( Istex/Corpus ); précédent : 005390; suivant : 005392Functional outcomes after extended surgery for gastric cancer
Auteurs : Y. Kurokawa ; M. Sasako ; T. Sano ; T. Shibata ; S. Ito ; A. Nashimoto ; A. Kurita ; T. KinoshitaSource :
- British Journal of Surgery [ 0007-1323 ] ; 2011-02.
Abstract
Extended gastrectomy with para‐aortic nodal dissection (PAND) or thorough dissection of mediastinal nodes using a left thoracoabdominal (LTA) approach is an alternative to D2 lymphadenectomy, with variable postoperative results.
Url:
DOI: 10.1002/bjs.7297
Links to Exploration step
ISTEX:B28D71C251419EF7A29E7DB78D9C09AEF94CD9D4Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Functional outcomes after extended surgery for gastric cancer</title><author><name sortKey="Kurokawa, Y" sort="Kurokawa, Y" uniqKey="Kurokawa Y" first="Y." last="Kurokawa">Y. Kurokawa</name><affiliation><mods:affiliation>Department of Surgery, Osaka National Hospital, Osaka, Japan</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, 2‐2‐E2, Yamadaoka, Suita, Osaka 565‐0871, Japan</mods:affiliation></affiliation></author><author><name sortKey="Sasako, M" sort="Sasako, M" uniqKey="Sasako M" first="M." last="Sasako">M. Sasako</name><affiliation><mods:affiliation>Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Sano, T" sort="Sano, T" uniqKey="Sano T" first="T." last="Sano">T. Sano</name><affiliation><mods:affiliation>Department of Surgery, Cancer Institute Ariake Hospital, Tokyo, Japan</mods:affiliation></affiliation></author><author><name sortKey="Shibata, T" sort="Shibata, T" uniqKey="Shibata T" first="T." last="Shibata">T. Shibata</name><affiliation><mods:affiliation>Department of Surgery, Japan Clinical Oncology Group Data Centre, Centre for Cancer Control and Information Services, National Cancer Centre, Tokyo, Japan</mods:affiliation></affiliation></author><author><name sortKey="Ito, S" sort="Ito, S" uniqKey="Ito S" first="S." last="Ito">S. Ito</name><affiliation><mods:affiliation>Department of Surgery, Aichi Cancer Centre, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Nashimoto, A" sort="Nashimoto, A" uniqKey="Nashimoto A" first="A." last="Nashimoto">A. Nashimoto</name><affiliation><mods:affiliation>Department of Surgery, Niigata Cancer Centre Hospital, Niigata, Japan</mods:affiliation></affiliation></author><author><name sortKey="Kurita, A" sort="Kurita, A" uniqKey="Kurita A" first="A." last="Kurita">A. Kurita</name><affiliation><mods:affiliation>Department of Surgery, National Shikoku Cancer Centre, Matsuyama, Japan</mods:affiliation></affiliation></author><author><name sortKey="Kinoshita, T" sort="Kinoshita, T" uniqKey="Kinoshita T" first="T." last="Kinoshita">T. Kinoshita</name><affiliation><mods:affiliation>Department of Surgery, National Cancer Centre Hospital East, Kashiwa, Japan</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:B28D71C251419EF7A29E7DB78D9C09AEF94CD9D4</idno><date when="2011" year="2011">2011</date><idno type="doi">10.1002/bjs.7297</idno><idno type="url">https://api.istex.fr/document/B28D71C251419EF7A29E7DB78D9C09AEF94CD9D4/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">005391</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">005391</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Functional outcomes after extended surgery for gastric cancer</title><author><name sortKey="Kurokawa, Y" sort="Kurokawa, Y" uniqKey="Kurokawa Y" first="Y." last="Kurokawa">Y. Kurokawa</name><affiliation><mods:affiliation>Department of Surgery, Osaka National Hospital, Osaka, Japan</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, 2‐2‐E2, Yamadaoka, Suita, Osaka 565‐0871, Japan</mods:affiliation></affiliation></author><author><name sortKey="Sasako, M" sort="Sasako, M" uniqKey="Sasako M" first="M." last="Sasako">M. Sasako</name><affiliation><mods:affiliation>Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Sano, T" sort="Sano, T" uniqKey="Sano T" first="T." last="Sano">T. Sano</name><affiliation><mods:affiliation>Department of Surgery, Cancer Institute Ariake Hospital, Tokyo, Japan</mods:affiliation></affiliation></author><author><name sortKey="Shibata, T" sort="Shibata, T" uniqKey="Shibata T" first="T." last="Shibata">T. Shibata</name><affiliation><mods:affiliation>Department of Surgery, Japan Clinical Oncology Group Data Centre, Centre for Cancer Control and Information Services, National Cancer Centre, Tokyo, Japan</mods:affiliation></affiliation></author><author><name sortKey="Ito, S" sort="Ito, S" uniqKey="Ito S" first="S." last="Ito">S. Ito</name><affiliation><mods:affiliation>Department of Surgery, Aichi Cancer Centre, Nagoya, Japan</mods:affiliation></affiliation></author><author><name sortKey="Nashimoto, A" sort="Nashimoto, A" uniqKey="Nashimoto A" first="A." last="Nashimoto">A. Nashimoto</name><affiliation><mods:affiliation>Department of Surgery, Niigata Cancer Centre Hospital, Niigata, Japan</mods:affiliation></affiliation></author><author><name sortKey="Kurita, A" sort="Kurita, A" uniqKey="Kurita A" first="A." last="Kurita">A. Kurita</name><affiliation><mods:affiliation>Department of Surgery, National Shikoku Cancer Centre, Matsuyama, Japan</mods:affiliation></affiliation></author><author><name sortKey="Kinoshita, T" sort="Kinoshita, T" uniqKey="Kinoshita T" first="T." last="Kinoshita">T. Kinoshita</name><affiliation><mods:affiliation>Department of Surgery, National Cancer Centre Hospital East, Kashiwa, Japan</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">British Journal of Surgery</title><title level="j" type="alt">BRITISH JOURNAL OF SURGERY</title><idno type="ISSN">0007-1323</idno><idno type="eISSN">1365-2168</idno><imprint><biblScope unit="vol">98</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="239">239</biblScope><biblScope unit="page" to="245">245</biblScope><biblScope unit="page-count">7</biblScope><publisher>John Wiley & Sons, Ltd.</publisher><pubPlace>Chichester, UK</pubPlace><date type="published" when="2011-02">2011-02</date></imprint><idno type="ISSN">0007-1323</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0007-1323</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">Extended gastrectomy with para‐aortic nodal dissection (PAND) or thorough dissection of mediastinal nodes using a left thoracoabdominal (LTA) approach is an alternative to D2 lymphadenectomy, with variable postoperative results.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>pand</json:string><json:string>gastric</json:string><json:string>favourable</json:string><json:string>lymphadenectomy</json:string><json:string>british journal</json:string><json:string>gastric cancer</json:string><json:string>node</json:string><json:string>oncology</json:string><json:string>gastrectomy</json:string><json:string>postoperative</json:string><json:string>randomized</json:string><json:string>thoracoabdominal</json:string><json:string>resection</json:string><json:string>kurokawa</json:string><json:string>john wiley sons</json:string><json:string>oncology group</json:string><json:string>bodyweight</json:string><json:string>favourable response</json:string><json:string>sano</json:string><json:string>respiratory function</json:string><json:string>sasako</json:string><json:string>nodal</json:string><json:string>jcog</json:string><json:string>tumour</json:string><json:string>favourable response proportion</json:string><json:string>surgery society</json:string><json:string>bowel</json:string><json:string>adenocarcinoma</json:string><json:string>surg</json:string><json:string>nodal dissection</json:string><json:string>dyspnoea</json:string><json:string>pand group</json:string><json:string>meal volume</json:string><json:string>bowel habit</json:string><json:string>vital capacity</json:string><json:string>incisional pain</json:string><json:string>surgery</json:string><json:string>present study</json:string><json:string>total gastrectomy</json:string><json:string>functional outcomes</json:string><json:string>cent intervals</json:string><json:string>symptom scores</json:string><json:string>clin oncol</json:string><json:string>symptom</json:string><json:string>dissection</json:string><json:string>centre</json:string></teeft></keywords><author><json:item><name>Y. Kurokawa</name><affiliations><json:string>Department of Surgery, Osaka National Hospital, Osaka, Japan</json:string><json:string>Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, 2‐2‐E2, Yamadaoka, Suita, Osaka 565‐0871, Japan</json:string></affiliations></json:item><json:item><name>M. Sasako</name><affiliations><json:string>Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan</json:string></affiliations></json:item><json:item><name>T. Sano</name><affiliations><json:string>Department of Surgery, Cancer Institute Ariake Hospital, Tokyo, Japan</json:string></affiliations></json:item><json:item><name>T. Shibata</name><affiliations><json:string>Department of Surgery, Japan Clinical Oncology Group Data Centre, Centre for Cancer Control and Information Services, National Cancer Centre, Tokyo, Japan</json:string></affiliations></json:item><json:item><name>S. Ito</name><affiliations><json:string>Department of Surgery, Aichi Cancer Centre, Nagoya, Japan</json:string></affiliations></json:item><json:item><name>A. Nashimoto</name><affiliations><json:string>Department of Surgery, Niigata Cancer Centre Hospital, Niigata, Japan</json:string></affiliations></json:item><json:item><name>A. Kurita</name><affiliations><json:string>Department of Surgery, National Shikoku Cancer Centre, Matsuyama, Japan</json:string></affiliations></json:item><json:item><name>T. Kinoshita</name><affiliations><json:string>Department of Surgery, National Cancer Centre Hospital East, Kashiwa, Japan</json:string></affiliations></json:item></author><articleId><json:string>BJS7297</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>Avoid left thoracoabdominal approach</abstract><qualityIndicators><score>4.384</score><pdfVersion>1.3</pdfVersion><pdfPageSize>595 x 782 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>228</abstractCharCount><pdfWordCount>4036</pdfWordCount><pdfCharCount>26603</pdfCharCount><pdfPageCount>8</pdfPageCount><abstractWordCount>29</abstractWordCount></qualityIndicators><title>Functional outcomes after extended surgery for gastric cancer</title><corporate><json:item><name>for the Japan Clinical Oncology Group</name></json:item></corporate><genre><json:string>article</json:string></genre><host><title>British Journal of Surgery</title><language><json:string>unknown</json:string></language><doi><json:string>10.1002/(ISSN)1365-2168</json:string></doi><issn><json:string>0007-1323</json:string></issn><eissn><json:string>1365-2168</json:string></eissn><publisherId><json:string>BJS</json:string></publisherId><volume>98</volume><issue>2</issue><pages><first>239</first><last>245</last><total>7</total></pages><genre><json:string>journal</json:string></genre><subject><json:item><value>Original Article</value></json:item></subject></host><categories><wos><json:string>science</json:string><json:string>surgery</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>clinical medicine</json:string><json:string>surgery</json:string></scienceMetrix><inist><json:string>sciences appliquees, technologies et medecines</json:string><json:string>sciences biologiques et medicales</json:string><json:string>sciences medicales</json:string></inist></categories><publicationDate>2011</publicationDate><copyrightDate>2011</copyrightDate><doi><json:string>10.1002/bjs.7297</json:string></doi><id>B28D71C251419EF7A29E7DB78D9C09AEF94CD9D4</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/B28D71C251419EF7A29E7DB78D9C09AEF94CD9D4/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/B28D71C251419EF7A29E7DB78D9C09AEF94CD9D4/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/B28D71C251419EF7A29E7DB78D9C09AEF94CD9D4/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Functional outcomes after extended surgery for gastric cancer</title></titleStmt><publicationStmt><publisher>John Wiley & Sons, Ltd.</publisher><pubPlace>Chichester, UK</pubPlace><availability><licence>Copyright © 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.</licence></availability><date type="published" when="2011-02"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main" xml:lang="en">Functional outcomes after extended surgery for gastric cancer</title><title level="a" type="short" xml:lang="en">Functional outcomes after extended surgery for gastric cancer</title><author xml:id="author-0000" role="corresp"><persName><forename type="first">Y.</forename><surname>Kurokawa</surname></persName><email>ykurokawa@gesurg.med.osaka‐u.ac.jp</email><affiliation>Department of Surgery, Osaka National Hospital, Osaka, Japan<address><country key="JP"></country></address></affiliation><affiliation>Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, 2‐2‐E2, Yamadaoka, Suita, Osaka 565‐0871, Japan</affiliation></author><author xml:id="author-0001"><persName><forename type="first">M.</forename><surname>Sasako</surname></persName><affiliation>Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan<address><country key="JP"></country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">T.</forename><surname>Sano</surname></persName><affiliation>Department of Surgery, Cancer Institute Ariake Hospital, Tokyo, Japan<address><country key="JP"></country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">T.</forename><surname>Shibata</surname></persName><affiliation>Department of Surgery, Japan Clinical Oncology Group Data Centre, Centre for Cancer Control and Information Services, National Cancer Centre, Tokyo, Japan<address><country key="JP"></country></address></affiliation></author><author xml:id="author-0004"><persName><forename type="first">S.</forename><surname>Ito</surname></persName><affiliation>Department of Surgery, Aichi Cancer Centre, Nagoya, Japan<address><country key="JP"></country></address></affiliation></author><author xml:id="author-0005"><persName><forename type="first">A.</forename><surname>Nashimoto</surname></persName><affiliation>Department of Surgery, Niigata Cancer Centre Hospital, Niigata, Japan<address><country key="JP"></country></address></affiliation></author><author xml:id="author-0006"><persName><forename type="first">A.</forename><surname>Kurita</surname></persName><affiliation>Department of Surgery, National Shikoku Cancer Centre, Matsuyama, Japan<address><country key="JP"></country></address></affiliation></author><author xml:id="author-0007"><persName><forename type="first">T.</forename><surname>Kinoshita</surname></persName><affiliation>Department of Surgery, National Cancer Centre Hospital East, Kashiwa, Japan<address><country key="JP"></country></address></affiliation></author><author xml:id="author-0008"><author><orgName>for the Japan Clinical Oncology Group</orgName></author></author><idno type="istex">B28D71C251419EF7A29E7DB78D9C09AEF94CD9D4</idno><idno type="DOI">10.1002/bjs.7297</idno><idno type="unit">BJS7297</idno><idno type="toTypesetVersion">file:BJS.BJS7297.pdf</idno></analytic><monogr><title level="j" type="main">British Journal of Surgery</title><title level="j" type="alt">BRITISH JOURNAL OF SURGERY</title><idno type="pISSN">0007-1323</idno><idno type="eISSN">1365-2168</idno><idno type="book-DOI">10.1002/(ISSN)1365-2168</idno><idno type="book-part-DOI">10.1002/bjs.v98.2</idno><idno type="product">BJS</idno><imprint><biblScope unit="vol">98</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="239">239</biblScope><biblScope unit="page" to="245">245</biblScope><biblScope unit="page-count">7</biblScope><publisher>John Wiley & Sons, Ltd.</publisher><pubPlace>Chichester, UK</pubPlace><date type="published" when="2011-02"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main"><head>Abstract</head>
Background:
<p>Extended gastrectomy with para‐aortic nodal dissection (PAND) or thorough dissection of mediastinal nodes using a left thoracoabdominal (LTA) approach is an alternative to D2 lymphadenectomy, with variable postoperative results.</p>
Methods:
<p>Two randomized controlled trials have been conducted to compare D2 lymphadenectomy alone (263 patients) <hi rend="italic">versus</hi> D2 lymphadenectomy plus PAND (260), and the abdominal–transhiatal (TH) approach (82) <hi rend="italic">versus</hi> the LTA approach (85), in patients with gastric cancer. Prospectively registered secondary endpoints bodyweight, symptom scores and respiratory function were evaluated in the present study.</p>
Results:
<p>Bodyweight was comparable after D2 and D2 plus PAND, but higher after TH than after LTA procedures at 1 and 3 years. At 1‐ and 3‐year follow‐up symptom scores were comparable between D2 and D2 plus PAND. A LTA approach resulted in significantly worse scores than a TH approach in terms of meal volume, return to work, incisional pain and dyspnoea up to 1 year. The decrease in vital capacity was significantly greater after LTA than TH procedures up to 6 months.</p>
Conclusion:
<p>Bodyweight and postoperative symptoms were not affected by adding PAND to a D2 procedure. A LTA approach aggravated weight loss, symptoms and respiratory functions compared with a TH approach. Registration numbers: NCT00149279, NCT00149266 (<ref type="url">http://www.clinicaltrials.gov</ref>). Copyright © 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.</p></abstract><abstract xml:lang="en" style="short"><p>Avoid left thoracoabdominal approach</p></abstract><textClass><classCode scheme="articleCategory">Original Article</classCode><classCode scheme="tocHeading1">Original Articles</classCode></textClass><langUsage><language ident="EN"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/B28D71C251419EF7A29E7DB78D9C09AEF94CD9D4/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>John Wiley & Sons, Ltd.</publisherName><publisherLoc>Chichester, UK</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1365-2168</doi><issn type="print">0007-1323</issn><issn type="electronic">1365-2168</issn><idGroup><id type="product" value="BJS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="BRITISH JOURNAL OF SURGERY">British Journal of Surgery</title><title type="short">Br J Surg</title></titleGroup></publicationMeta><publicationMeta level="part" position="20"><doi origin="wiley" registered="yes">10.1002/bjs.v98.2</doi><numberingGroup><numbering type="journalVolume" number="98">98</numbering><numbering type="journalIssue">2</numbering></numberingGroup><coverDate startDate="2011-02">February 2011</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="120" status="forIssue"><doi origin="wiley" registered="yes">10.1002/bjs.7297</doi><idGroup><id type="unit" value="BJS7297"></id></idGroup><countGroup><count type="pageTotal" number="7"></count></countGroup><titleGroup><title type="articleCategory">Original Article</title><title type="tocHeading1">Original Articles</title></titleGroup><copyright ownership="thirdParty">Copyright © 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.</copyright><eventGroup><event type="manuscriptAccepted" date="2010-08-26"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.4.2 mode:FullText mathml2tex" date="2010-12-22"></event><event type="publishedOnlineEarlyUnpaginated" date="2010-11-22"></event><event type="firstOnline" date="2010-11-22"></event><event type="publishedOnlineFinalForm" date="2010-12-22"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-07"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-15"></event></eventGroup><numberingGroup><numbering type="pageFirst">239</numbering><numbering type="pageLast">245</numbering></numberingGroup><correspondenceTo>Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, 2‐2‐E2, Yamadaoka, Suita, Osaka 565‐0871, Japan</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:BJS.BJS7297.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="2"></count><count type="tableTotal" number="3"></count><count type="referenceTotal" number="15"></count></countGroup><titleGroup><title type="main" xml:lang="en">Functional outcomes after extended surgery for gastric cancer</title><title type="short" xml:lang="en">Functional outcomes after extended surgery for gastric cancer</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Y.</givenNames><familyName>Kurokawa</familyName></personName><contactDetails><email normalForm="ykurokawa@gesurg.med.osaka-u.ac.jp">ykurokawa@gesurg.med.osaka‐u.ac.jp</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af2"><personName><givenNames>M.</givenNames><familyName>Sasako</familyName></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af3"><personName><givenNames>T.</givenNames><familyName>Sano</familyName></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af8"><personName><givenNames>T.</givenNames><familyName>Shibata</familyName></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af4"><personName><givenNames>S.</givenNames><familyName>Ito</familyName></personName></creator><creator xml:id="au6" creatorRole="author" affiliationRef="#af5"><personName><givenNames>A.</givenNames><familyName>Nashimoto</familyName></personName></creator><creator xml:id="au7" creatorRole="author" affiliationRef="#af6"><personName><givenNames>A.</givenNames><familyName>Kurita</familyName></personName></creator><creator xml:id="au8" creatorRole="author" affiliationRef="#af7"><personName><givenNames>T.</givenNames><familyName>Kinoshita</familyName></personName></creator><creator xml:id="au9" creatorRole="author"><groupName>for the Japan Clinical Oncology Group</groupName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="JP" type="organization"><unparsedAffiliation>Department of Surgery, Osaka National Hospital, Osaka, Japan</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="JP" type="organization"><unparsedAffiliation>Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="JP" type="organization"><unparsedAffiliation>Department of Surgery, Cancer Institute Ariake Hospital, Tokyo, Japan</unparsedAffiliation></affiliation><affiliation xml:id="af4" countryCode="JP" type="organization"><unparsedAffiliation>Department of Surgery, Aichi Cancer Centre, Nagoya, Japan</unparsedAffiliation></affiliation><affiliation xml:id="af5" countryCode="JP" type="organization"><unparsedAffiliation>Department of Surgery, Niigata Cancer Centre Hospital, Niigata, Japan</unparsedAffiliation></affiliation><affiliation xml:id="af6" countryCode="JP" type="organization"><unparsedAffiliation>Department of Surgery, National Shikoku Cancer Centre, Matsuyama, Japan</unparsedAffiliation></affiliation><affiliation xml:id="af7" countryCode="JP" type="organization"><unparsedAffiliation>Department of Surgery, National Cancer Centre Hospital East, Kashiwa, Japan</unparsedAffiliation></affiliation><affiliation xml:id="af8" countryCode="JP" type="organization"><unparsedAffiliation>Department of Surgery, Japan Clinical Oncology Group Data Centre, Centre for Cancer Control and Information Services, National Cancer Centre, Tokyo, Japan</unparsedAffiliation></affiliation></affiliationGroup><supportingInformation><supportingInfoItem><mediaResource alt="supporting information" href="urn-x:wiley:00071323:media:bjs7297:bjs_7297_suppinfo"></mediaResource><caption>Supporting Information</caption></supportingInfoItem></supportingInformation><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><section xml:id="abs1-1"><title type="main">Background:</title><p>Extended gastrectomy with para‐aortic nodal dissection (PAND) or thorough dissection of mediastinal nodes using a left thoracoabdominal (LTA) approach is an alternative to D2 lymphadenectomy, with variable postoperative results.</p></section><section xml:id="abs1-2"><title type="main">Methods:</title><p>Two randomized controlled trials have been conducted to compare D2 lymphadenectomy alone (263 patients) <i>versus</i> D2 lymphadenectomy plus PAND (260), and the abdominal–transhiatal (TH) approach (82) <i>versus</i> the LTA approach (85), in patients with gastric cancer. Prospectively registered secondary endpoints bodyweight, symptom scores and respiratory function were evaluated in the present study.</p></section><section xml:id="abs1-3"><title type="main">Results:</title><p>Bodyweight was comparable after D2 and D2 plus PAND, but higher after TH than after LTA procedures at 1 and 3 years. At 1‐ and 3‐year follow‐up symptom scores were comparable between D2 and D2 plus PAND. A LTA approach resulted in significantly worse scores than a TH approach in terms of meal volume, return to work, incisional pain and dyspnoea up to 1 year. The decrease in vital capacity was significantly greater after LTA than TH procedures up to 6 months.</p></section><section xml:id="abs1-4"><title type="main">Conclusion:</title><p>Bodyweight and postoperative symptoms were not affected by adding PAND to a D2 procedure. A LTA approach aggravated weight loss, symptoms and respiratory functions compared with a TH approach. Registration numbers: NCT00149279, NCT00149266 (<url href="http://www.clinicaltrials.gov">http://www.clinicaltrials.gov</url>). Copyright © 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.</p></section></abstract><abstract type="short" xml:lang="en"><p>Avoid left thoracoabdominal approach</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Functional outcomes after extended surgery for gastric cancer</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Functional outcomes after extended surgery for gastric cancer</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Functional outcomes after extended surgery for gastric cancer</title></titleInfo><name type="personal"><namePart type="given">Y.</namePart><namePart type="family">Kurokawa</namePart><affiliation>Department of Surgery, Osaka National Hospital, Osaka, Japan</affiliation><affiliation>Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, 2‐2‐E2, Yamadaoka, Suita, Osaka 565‐0871, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Sasako</namePart><affiliation>Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T.</namePart><namePart type="family">Sano</namePart><affiliation>Department of Surgery, Cancer Institute Ariake Hospital, Tokyo, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T.</namePart><namePart type="family">Shibata</namePart><affiliation>Department of Surgery, Japan Clinical Oncology Group Data Centre, Centre for Cancer Control and Information Services, National Cancer Centre, Tokyo, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S.</namePart><namePart type="family">Ito</namePart><affiliation>Department of Surgery, Aichi Cancer Centre, Nagoya, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A.</namePart><namePart type="family">Nashimoto</namePart><affiliation>Department of Surgery, Niigata Cancer Centre Hospital, Niigata, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A.</namePart><namePart type="family">Kurita</namePart><affiliation>Department of Surgery, National Shikoku Cancer Centre, Matsuyama, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T.</namePart><namePart type="family">Kinoshita</namePart><affiliation>Department of Surgery, National Cancer Centre Hospital East, Kashiwa, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="corporate"><namePart>for the Japan Clinical Oncology Group</namePart><description>Department of Surgery, Osaka National Hospital, Osaka, JapanDepartment of Surgery, Hyogo College of Medicine, Nishinomiya, JapanDepartment of Surgery, Cancer Institute Ariake Hospital, Tokyo, JapanDepartment of Surgery, Aichi Cancer Centre, Nagoya, JapanDepartment of Surgery, Niigata Cancer Centre Hospital, Niigata, JapanDepartment of Surgery, National Shikoku Cancer Centre, Matsuyama, JapanDepartment of Surgery, National Cancer Centre Hospital East, Kashiwa, JapanDepartment of Surgery, Japan Clinical Oncology Group Data Centre, Centre for Cancer Control and Information Services, National Cancer Centre, Tokyo, Japan</description></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>John Wiley & Sons, Ltd.</publisher><place><placeTerm type="text">Chichester, UK</placeTerm></place><dateIssued encoding="w3cdtf">2011-02</dateIssued><dateValid encoding="w3cdtf">2010-08-26</dateValid><copyrightDate encoding="w3cdtf">2011</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">2</extent><extent unit="tables">3</extent><extent unit="references">15</extent></physicalDescription><abstract>Extended gastrectomy with para‐aortic nodal dissection (PAND) or thorough dissection of mediastinal nodes using a left thoracoabdominal (LTA) approach is an alternative to D2 lymphadenectomy, with variable postoperative results.</abstract><abstract>Two randomized controlled trials have been conducted to compare D2 lymphadenectomy alone (263 patients) versus D2 lymphadenectomy plus PAND (260), and the abdominal–transhiatal (TH) approach (82) versus the LTA approach (85), in patients with gastric cancer. Prospectively registered secondary endpoints bodyweight, symptom scores and respiratory function were evaluated in the present study.</abstract><abstract>Bodyweight was comparable after D2 and D2 plus PAND, but higher after TH than after LTA procedures at 1 and 3 years. At 1‐ and 3‐year follow‐up symptom scores were comparable between D2 and D2 plus PAND. A LTA approach resulted in significantly worse scores than a TH approach in terms of meal volume, return to work, incisional pain and dyspnoea up to 1 year. The decrease in vital capacity was significantly greater after LTA than TH procedures up to 6 months.</abstract><abstract>Bodyweight and postoperative symptoms were not affected by adding PAND to a D2 procedure. A LTA approach aggravated weight loss, symptoms and respiratory functions compared with a TH approach. Registration numbers: NCT00149279, NCT00149266 (http://www.clinicaltrials.gov). Copyright © 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.</abstract><abstract type="short" lang="en">Avoid left thoracoabdominal approach</abstract><note type="additional physical form">Supporting Information</note><relatedItem type="host"><titleInfo><title>British Journal of Surgery</title></titleInfo><titleInfo type="abbreviated"><title>Br J Surg</title></titleInfo><genre type="journal">journal</genre><subject><genre>article-category</genre><topic>Original Article</topic></subject><identifier type="ISSN">0007-1323</identifier><identifier type="eISSN">1365-2168</identifier><identifier type="DOI">10.1002/(ISSN)1365-2168</identifier><identifier type="PublisherID">BJS</identifier><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>98</number></detail><detail type="issue"><caption>no.</caption><number>2</number></detail><extent unit="pages"><start>239</start><end>245</end><total>7</total></extent></part></relatedItem><identifier type="istex">B28D71C251419EF7A29E7DB78D9C09AEF94CD9D4</identifier><identifier type="DOI">10.1002/bjs.7297</identifier><identifier type="ArticleID">BJS7297</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>John Wiley & Sons, Ltd.</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005391 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 005391 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:B28D71C251419EF7A29E7DB78D9C09AEF94CD9D4
|texte= Functional outcomes after extended surgery for gastric cancer
}}
| This area was generated with Dilib version V0.6.31. |  |