P‐88 Endocrine dermatosis and granulosa cell tumour in a red panda
Identifieur interne : 002A54 ( Istex/Corpus ); précédent : 002A53; suivant : 002A55P‐88 Endocrine dermatosis and granulosa cell tumour in a red panda
Auteurs : K. Alton ; H. Vielgrader ; T. Voracek ; W. ZenkerSource :
- Veterinary Dermatology [ 0959-4493 ] ; 2004-08.
Abstract
A 9‐year‐old red panda from the Vienna Zoo showed progressive hair loss of 2 years duration beginning at the tip of the tail and slowly spreading to the lower back, abdomen and thorax. Severe pruritus and mild automutilation was present only at the tail. Antifungal and antibiotic therapy showed little effect. Skin biopsies showed a thin hyperkeratotic epidermis, moderate superficial dermal sclerosis, mild superficial pyoderma, and complete atrophy of hair follicles and adnexae. Ultrasonography revealed an anechogenic circular mass 3 cm in diameter limited by echogenic trabeculae. The animal was euthanized. Necropsy revealed two smooth red‐brown soft solid nodules (3×3×2 cm) situated bilaterally at the caudal pole of the kidneys. Viscera, thyroid and adrenal glands as well as the uterus showed normal macroscopic and histologic appearance. Histologically, the pararenal nodules were recognized as enlarged ovaries with a small number of follicles and a large solid mass of slightly atypical vacuolated polygonal cells of Leydig‐cell character, which partly invaded the adjacent adipose tissue and were accompanied by discrete and strongly vascular stroma. Diagnosis of bilateral granulosa cell tumour was made. We concluded that the progressive hypotrichotic dermatosis was due to an endocrine abnormality. Funding: Self‐funded.
Url:
DOI: 10.1111/j.1365-3164.2004.00414_88.x
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Endocrine dermatosis and granulosa cell tumour in a red panda</title>
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<front><div type="abstract" xml:lang="en">A 9‐year‐old red panda from the Vienna Zoo showed progressive hair loss of 2 years duration beginning at the tip of the tail and slowly spreading to the lower back, abdomen and thorax. Severe pruritus and mild automutilation was present only at the tail. Antifungal and antibiotic therapy showed little effect. Skin biopsies showed a thin hyperkeratotic epidermis, moderate superficial dermal sclerosis, mild superficial pyoderma, and complete atrophy of hair follicles and adnexae. Ultrasonography revealed an anechogenic circular mass 3 cm in diameter limited by echogenic trabeculae. The animal was euthanized. Necropsy revealed two smooth red‐brown soft solid nodules (3×3×2 cm) situated bilaterally at the caudal pole of the kidneys. Viscera, thyroid and adrenal glands as well as the uterus showed normal macroscopic and histologic appearance. Histologically, the pararenal nodules were recognized as enlarged ovaries with a small number of follicles and a large solid mass of slightly atypical vacuolated polygonal cells of Leydig‐cell character, which partly invaded the adjacent adipose tissue and were accompanied by discrete and strongly vascular stroma. Diagnosis of bilateral granulosa cell tumour was made. We concluded that the progressive hypotrichotic dermatosis was due to an endocrine abnormality. Funding: Self‐funded.</div>
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<abstract>A 9‐year‐old red panda from the Vienna Zoo showed progressive hair loss of 2 years duration beginning at the tip of the tail and slowly spreading to the lower back, abdomen and thorax. Severe pruritus and mild automutilation was present only at the tail. Antifungal and antibiotic therapy showed little effect. Skin biopsies showed a thin hyperkeratotic epidermis, moderate superficial dermal sclerosis, mild superficial pyoderma, and complete atrophy of hair follicles and adnexae. Ultrasonography revealed an anechogenic circular mass 3 cm in diameter limited by echogenic trabeculae. The animal was euthanized. Necropsy revealed two smooth red‐brown soft solid nodules (3×3×2 cm) situated bilaterally at the caudal pole of the kidneys. Viscera, thyroid and adrenal glands as well as the uterus showed normal macroscopic and histologic appearance. Histologically, the pararenal nodules were recognized as enlarged ovaries with a small number of follicles and a large solid mass of slightly atypical vacuolated polygonal cells of Leydig‐cell character, which partly invaded the adjacent adipose tissue and were accompanied by discrete and strongly vascular stroma. Diagnosis of bilateral granulosa cell tumour was made. We concluded that the progressive hypotrichotic dermatosis was due to an endocrine abnormality. Funding: Self‐funded.</abstract>
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