Chronic eyelid lymphedema and acne rosacea
Identifieur interne : 002397 ( Istex/Corpus ); précédent : 002396; suivant : 002398Chronic eyelid lymphedema and acne rosacea
Auteurs : Francesco P. Bernardini ; Robert C. Kersten ; Lucie M. Khouri ; Muhammad Moin ; Dwight R. Kulwin ; Diya F. MutasimSource :
- Ophthalmology [ 0161-6420 ] ; 2000.
Abstract
Objective The authors describe the clinical findings and surgical treatment of two patients affected by chronic eyelid lymphedema associated with facial acne rosacea.Design Two interventional case reports.Methods and intervention The clinical diagnosis of acne rosacea was based on the physical examination and confirmed by the histopathologic findings obtained from biopsy of the involved tissue. Surgical treatment was required to address the disfiguring chronic eyelid lymphedema and to correct the resultant mechanical lower eyelid ectropion in both patients.Results Surgical debulking of the affected soft tissue resulted in very satisfactory cosmetic and functional improvement in both patients.Conclusions To our knowledge, this is the first series of cases of chronic eyelid lymphedema secondary to acne rosacea reported in the ophthalmic literature. Six similar cases have been described previously in the dermatologic literature; all of which had been treated medically without satisfactory results. Surgical debulking of the involved eyelids should be considered in patients affected by persistent symptomatic rosacea lymphedema.
Url:
DOI: 10.1016/S0161-6420(00)00429-2
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ISTEX:4E4972AC96A9721D78234B5429F26575F1B99CADLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Chronic eyelid lymphedema and acne rosacea</title><author><name sortKey="Bernardini, Francesco P" sort="Bernardini, Francesco P" uniqKey="Bernardini F" first="Francesco P" last="Bernardini">Francesco P. Bernardini</name><affiliation><mods:affiliation>Ophthalmology Clinic, S. Martino Hospital, University of Genova School of Medicine, Genova, Italy</mods:affiliation></affiliation></author><author><name sortKey="Kersten, Robert C" sort="Kersten, Robert C" uniqKey="Kersten R" first="Robert C" last="Kersten">Robert C. Kersten</name><affiliation><mods:affiliation>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</mods:affiliation></affiliation></author><author><name sortKey="Khouri, Lucie M" sort="Khouri, Lucie M" uniqKey="Khouri L" first="Lucie M" last="Khouri">Lucie M. Khouri</name><affiliation><mods:affiliation>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</mods:affiliation></affiliation></author><author><name sortKey="Moin, Muhammad" sort="Moin, Muhammad" uniqKey="Moin M" first="Muhammad" last="Moin">Muhammad Moin</name><affiliation><mods:affiliation>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</mods:affiliation></affiliation></author><author><name sortKey="Kulwin, Dwight R" sort="Kulwin, Dwight R" uniqKey="Kulwin D" first="Dwight R" last="Kulwin">Dwight R. Kulwin</name><affiliation><mods:affiliation>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</mods:affiliation></affiliation></author><author><name sortKey="Mutasim, Diya F" sort="Mutasim, Diya F" uniqKey="Mutasim D" first="Diya F" last="Mutasim">Diya F. Mutasim</name><affiliation><mods:affiliation>Department of Dermatology, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:4E4972AC96A9721D78234B5429F26575F1B99CAD</idno><date when="2000" year="2000">2000</date><idno type="doi">10.1016/S0161-6420(00)00429-2</idno><idno type="url">https://api.istex.fr/document/4E4972AC96A9721D78234B5429F26575F1B99CAD/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002397</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002397</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Chronic eyelid lymphedema and acne rosacea</title><author><name sortKey="Bernardini, Francesco P" sort="Bernardini, Francesco P" uniqKey="Bernardini F" first="Francesco P" last="Bernardini">Francesco P. Bernardini</name><affiliation><mods:affiliation>Ophthalmology Clinic, S. Martino Hospital, University of Genova School of Medicine, Genova, Italy</mods:affiliation></affiliation></author><author><name sortKey="Kersten, Robert C" sort="Kersten, Robert C" uniqKey="Kersten R" first="Robert C" last="Kersten">Robert C. Kersten</name><affiliation><mods:affiliation>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</mods:affiliation></affiliation></author><author><name sortKey="Khouri, Lucie M" sort="Khouri, Lucie M" uniqKey="Khouri L" first="Lucie M" last="Khouri">Lucie M. Khouri</name><affiliation><mods:affiliation>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</mods:affiliation></affiliation></author><author><name sortKey="Moin, Muhammad" sort="Moin, Muhammad" uniqKey="Moin M" first="Muhammad" last="Moin">Muhammad Moin</name><affiliation><mods:affiliation>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</mods:affiliation></affiliation></author><author><name sortKey="Kulwin, Dwight R" sort="Kulwin, Dwight R" uniqKey="Kulwin D" first="Dwight R" last="Kulwin">Dwight R. Kulwin</name><affiliation><mods:affiliation>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</mods:affiliation></affiliation></author><author><name sortKey="Mutasim, Diya F" sort="Mutasim, Diya F" uniqKey="Mutasim D" first="Diya F" last="Mutasim">Diya F. Mutasim</name><affiliation><mods:affiliation>Department of Dermatology, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Ophthalmology</title><title level="j" type="abbrev">OPHTHA</title><idno type="ISSN">0161-6420</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="2000">2000</date><biblScope unit="volume">107</biblScope><biblScope unit="issue">12</biblScope><biblScope unit="page" from="2220">2220</biblScope><biblScope unit="page" to="2223">2223</biblScope></imprint><idno type="ISSN">0161-6420</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0161-6420</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objective The authors describe the clinical findings and surgical treatment of two patients affected by chronic eyelid lymphedema associated with facial acne rosacea.Design Two interventional case reports.Methods and intervention The clinical diagnosis of acne rosacea was based on the physical examination and confirmed by the histopathologic findings obtained from biopsy of the involved tissue. Surgical treatment was required to address the disfiguring chronic eyelid lymphedema and to correct the resultant mechanical lower eyelid ectropion in both patients.Results Surgical debulking of the affected soft tissue resulted in very satisfactory cosmetic and functional improvement in both patients.Conclusions To our knowledge, this is the first series of cases of chronic eyelid lymphedema secondary to acne rosacea reported in the ophthalmic literature. Six similar cases have been described previously in the dermatologic literature; all of which had been treated medically without satisfactory results. Surgical debulking of the involved eyelids should be considered in patients affected by persistent symptomatic rosacea lymphedema.</div></front></TEI><istex><corpusName>elsevier</corpusName><keywords><teeft><json:string>rosacea</json:string><json:string>lymphedema</json:string><json:string>acne</json:string><json:string>eyelid</json:string><json:string>acne rosacea</json:string><json:string>chronic eyelid lymphedema</json:string><json:string>erythema</json:string><json:string>chronic lymphedema</json:string><json:string>dermatol</json:string><json:string>debulking</json:string><json:string>upper cheeks</json:string><json:string>ophthalmology</json:string><json:string>rosaceous</json:string><json:string>rosaceous lymphedema</json:string><json:string>ndings</json:string><json:string>lower eyelids</json:string><json:string>surgical debulking</json:string><json:string>lower eyelid</json:string><json:string>case report</json:string><json:string>arch dermatol</json:string><json:string>dermatologic literature</json:string><json:string>surgical</json:string><json:string>edema</json:string><json:string>hormone levels</json:string><json:string>ophthalmic literature</json:string><json:string>functional improvement</json:string><json:string>barrett center</json:string><json:string>upper eyelid</json:string><json:string>visual acuity</json:string><json:string>laboratory studies</json:string><json:string>complete blood count</json:string><json:string>blood cell count</json:string><json:string>eosinophil level</json:string><json:string>erythrocyte sedimentation rate</json:string><json:string>liver function tests</json:string><json:string>cincinnati school</json:string><json:string>serum creatinine levels</json:string><json:string>chest radiograph</json:string><json:string>soft tissue</json:string><json:string>punch biopsy</json:string><json:string>dermal edema</json:string><json:string>facial acne rosacea</json:string><json:string>mechanical ectropion</json:string><json:string>orbicularis muscle</json:string><json:string>orbital septum</json:string><json:string>rare variant</json:string><json:string>common disorder</json:string><json:string>surgical treatment</json:string><json:string>american academy</json:string><json:string>oral macrolide antibiotics</json:string></teeft></keywords><author><json:item><name>Francesco P Bernardini MD</name><affiliations><json:string>Ophthalmology Clinic, S. Martino Hospital, University of Genova School of Medicine, Genova, Italy</json:string></affiliations></json:item><json:item><name>Robert C Kersten MD</name><affiliations><json:string>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</json:string></affiliations></json:item><json:item><name>Lucie M Khouri MD</name><affiliations><json:string>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</json:string></affiliations></json:item><json:item><name>Muhammad Moin</name><affiliations><json:string>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</json:string></affiliations></json:item><json:item><name>Dwight R Kulwin MD</name><affiliations><json:string>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</json:string></affiliations></json:item><json:item><name>Diya F Mutasim MD</name><affiliations><json:string>Department of Dermatology, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</json:string></affiliations></json:item></author><language><json:string>eng</json:string></language><originalGenre><json:string>Full-length article</json:string></originalGenre><abstract>Objective The authors describe the clinical findings and surgical treatment of two patients affected by chronic eyelid lymphedema associated with facial acne rosacea.Design Two interventional case reports.Methods and intervention The clinical diagnosis of acne rosacea was based on the physical examination and confirmed by the histopathologic findings obtained from biopsy of the involved tissue. Surgical treatment was required to address the disfiguring chronic eyelid lymphedema and to correct the resultant mechanical lower eyelid ectropion in both patients.Results Surgical debulking of the affected soft tissue resulted in very satisfactory cosmetic and functional improvement in both patients.Conclusions To our knowledge, this is the first series of cases of chronic eyelid lymphedema secondary to acne rosacea reported in the ophthalmic literature. Six similar cases have been described previously in the dermatologic literature; all of which had been treated medically without satisfactory results. Surgical debulking of the involved eyelids should be considered in patients affected by persistent symptomatic rosacea lymphedema.</abstract><qualityIndicators><score>3.368</score><pdfVersion>1.2</pdfVersion><pdfPageSize>586 x 786 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>0</keywordCount><abstractCharCount>1140</abstractCharCount><pdfWordCount>1496</pdfWordCount><pdfCharCount>10473</pdfCharCount><pdfPageCount>4</pdfPageCount><abstractWordCount>156</abstractWordCount></qualityIndicators><title>Chronic eyelid lymphedema and acne rosacea</title><pii><json:string>S0161-6420(00)00429-2</json:string></pii><genre><json:string>research-article</json:string></genre><host><title>Ophthalmology</title><language><json:string>unknown</json:string></language><publicationDate>2000</publicationDate><issn><json:string>0161-6420</json:string></issn><pii><json:string>S0161-6420(00)X0013-9</json:string></pii><volume>107</volume><issue>12</issue><pages><first>2220</first><last>2223</last></pages><genre><json:string>journal</json:string></genre></host><categories><wos><json:string>science</json:string><json:string>ophthalmology</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>clinical medicine</json:string><json:string>ophthalmology & optometry</json:string></scienceMetrix><inist><json:string>sciences appliquees, technologies et medecines</json:string><json:string>sciences biologiques et medicales</json:string><json:string>sciences medicales</json:string></inist></categories><publicationDate>2000</publicationDate><copyrightDate>2000</copyrightDate><doi><json:string>10.1016/S0161-6420(00)00429-2</json:string></doi><id>4E4972AC96A9721D78234B5429F26575F1B99CAD</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/4E4972AC96A9721D78234B5429F26575F1B99CAD/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/4E4972AC96A9721D78234B5429F26575F1B99CAD/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/4E4972AC96A9721D78234B5429F26575F1B99CAD/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Chronic eyelid lymphedema and acne rosacea</title><title level="a" type="sub" xml:lang="en">Report of two cases</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>ELSEVIER</publisher><availability><p>©2000 American Academy of Ophthalmology, Inc.</p></availability><date>2000</date></publicationStmt><notesStmt><note>Manuscript no. 99748.</note><note type="content">Figure 1: Chronic lymphedema affecting both lower eyelids and left upper eyelid. The figure shows marked erythema of the involved eyelids and scattered teleangectasias of upper cheeks.</note><note type="content">Figure 2: Histologic examination of the excision specimen from patient 1 reveals dilated lymphatic channels and lymphocytic infiltrate (arrow; stain, hematoxylin–eosin; original magnification ×100).</note><note type="content">Figure 3: Chronic lymphedema affecting the right lower eyelid. The figure shows marked erythema and teleangectasias of the skin overlying eyelids and upper cheeks.</note><note type="content">Figure 4: Patient 1 after debulking and horizontal tightening (3 weeks after surgery).</note><note type="content">Figure 5: Patient 2 after debulking and horizontal tightening (2 weeks after surgery).</note><note type="content">Table 1: Differential Diagnosis of Chronic Facial Edema legend</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Chronic eyelid lymphedema and acne rosacea</title><title level="a" type="sub" xml:lang="en">Report of two cases</title><author xml:id="author-0000"><persName><forename type="first">Francesco P</forename><surname>Bernardini</surname></persName><roleName type="degree">MD</roleName><affiliation>Ophthalmology Clinic, S. Martino Hospital, University of Genova School of Medicine, Genova, Italy</affiliation></author><author xml:id="author-0001"><persName><forename type="first">Robert C</forename><surname>Kersten</surname></persName><roleName type="degree">MD</roleName><note type="biography">Reprints requests to Robert C. Kersten, MD, The University of Cincinnati Medical Center, The Barrett Center, P.O. Box 670670, Cincinnati, OH 45267-0670</note><affiliation>Reprints requests to Robert C. Kersten, MD, The University of Cincinnati Medical Center, The Barrett Center, P.O. Box 670670, Cincinnati, OH 45267-0670</affiliation><affiliation>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</affiliation></author><author xml:id="author-0002"><persName><forename type="first">Lucie M</forename><surname>Khouri</surname></persName><roleName type="degree">MD</roleName><affiliation>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</affiliation></author><author xml:id="author-0003"><persName><forename type="first">Muhammad</forename><surname>Moin</surname></persName><note type="biography">FRCOphth</note><affiliation>FRCOphth</affiliation><affiliation>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</affiliation></author><author xml:id="author-0004"><persName><forename type="first">Dwight R</forename><surname>Kulwin</surname></persName><roleName type="degree">MD</roleName><affiliation>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</affiliation></author><author xml:id="author-0005"><persName><forename type="first">Diya F</forename><surname>Mutasim</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Dermatology, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</affiliation></author><idno type="istex">4E4972AC96A9721D78234B5429F26575F1B99CAD</idno><idno type="DOI">10.1016/S0161-6420(00)00429-2</idno><idno type="PII">S0161-6420(00)00429-2</idno></analytic><monogr><title level="j">Ophthalmology</title><title level="j" type="abbrev">OPHTHA</title><idno type="pISSN">0161-6420</idno><idno type="PII">S0161-6420(00)X0013-9</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="2000"></date><biblScope unit="volume">107</biblScope><biblScope unit="issue">12</biblScope><biblScope unit="page" from="2220">2220</biblScope><biblScope unit="page" to="2223">2223</biblScope></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2000</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Objective The authors describe the clinical findings and surgical treatment of two patients affected by chronic eyelid lymphedema associated with facial acne rosacea.Design Two interventional case reports.Methods and intervention The clinical diagnosis of acne rosacea was based on the physical examination and confirmed by the histopathologic findings obtained from biopsy of the involved tissue. Surgical treatment was required to address the disfiguring chronic eyelid lymphedema and to correct the resultant mechanical lower eyelid ectropion in both patients.Results Surgical debulking of the affected soft tissue resulted in very satisfactory cosmetic and functional improvement in both patients.Conclusions To our knowledge, this is the first series of cases of chronic eyelid lymphedema secondary to acne rosacea reported in the ophthalmic literature. Six similar cases have been described previously in the dermatologic literature; all of which had been treated medically without satisfactory results. Surgical debulking of the involved eyelids should be considered in patients affected by persistent symptomatic rosacea lymphedema.</p></abstract></profileDesc><revisionDesc><change when="2000">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/4E4972AC96A9721D78234B5429F26575F1B99CAD/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: ce:floats; body; tail"><istex:xmlDeclaration>version="1.0" encoding="utf-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"><istex:entity SYSTEM="gr1" NDATA="IMAGE" name="GR1"></istex:entity><istex:entity SYSTEM="gr2" NDATA="IMAGE" name="GR2"></istex:entity><istex:entity SYSTEM="gr3" NDATA="IMAGE" name="GR3"></istex:entity><istex:entity SYSTEM="gr4" NDATA="IMAGE" name="GR4"></istex:entity><istex:entity SYSTEM="gr5" NDATA="IMAGE" name="GR5"></istex:entity></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="fla" xml:lang="en"><item-info><jid>OPHTHA</jid><aid>611</aid><ce:pii>S0161-6420(00)00429-2</ce:pii><ce:doi>10.1016/S0161-6420(00)00429-2</ce:doi><ce:copyright type="society" year="2000">American Academy of Ophthalmology, Inc.</ce:copyright></item-info><head><ce:title>Chronic eyelid lymphedema and acne rosacea</ce:title><ce:subtitle>Report of two cases</ce:subtitle><ce:author-group><ce:author><ce:given-name>Francesco P</ce:given-name><ce:surname>Bernardini</ce:surname><ce:degrees>MD</ce:degrees><ce:cross-ref refid="AFF1"><ce:sup>1</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Robert C</ce:given-name><ce:surname>Kersten</ce:surname><ce:degrees>MD</ce:degrees><ce:cross-ref refid="AFF2"><ce:sup>2</ce:sup></ce:cross-ref><ce:cross-ref refid="CORR1">*</ce:cross-ref></ce:author><ce:author><ce:given-name>Lucie M</ce:given-name><ce:surname>Khouri</ce:surname><ce:degrees>MD</ce:degrees><ce:cross-ref refid="AFF2"><ce:sup>2</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Muhammad</ce:given-name><ce:surname>Moin</ce:surname><ce:roles>FRCOphth</ce:roles><ce:cross-ref refid="AFF2"><ce:sup>2</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Dwight R</ce:given-name><ce:surname>Kulwin</ce:surname><ce:degrees>MD</ce:degrees><ce:cross-ref refid="AFF2"><ce:sup>2</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Diya F</ce:given-name><ce:surname>Mutasim</ce:surname><ce:degrees>MD</ce:degrees><ce:cross-ref refid="AFF3"><ce:sup>3</ce:sup></ce:cross-ref></ce:author><ce:affiliation id="AFF1"><ce:label>1</ce:label><ce:textfn>Ophthalmology Clinic, S. Martino Hospital, University of Genova School of Medicine, Genova, Italy</ce:textfn></ce:affiliation><ce:affiliation id="AFF2"><ce:label>2</ce:label><ce:textfn>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</ce:textfn></ce:affiliation><ce:affiliation id="AFF3"><ce:label>3</ce:label><ce:textfn>Department of Dermatology, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</ce:textfn></ce:affiliation><ce:correspondence id="CORR1"><ce:label>*</ce:label><ce:text>Reprints requests to Robert C. Kersten, MD, The University of Cincinnati Medical Center, The Barrett Center, P.O. Box 670670, Cincinnati, OH 45267-0670</ce:text></ce:correspondence></ce:author-group><ce:date-received day="10" month="11" year="1999"></ce:date-received><ce:date-accepted day="19" month="7" year="2000"></ce:date-accepted><ce:miscellaneous>Manuscript no. 99748.</ce:miscellaneous><ce:abstract><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:section-title>Objective</ce:section-title><ce:simple-para>The authors describe the clinical findings and surgical treatment of two patients affected by chronic eyelid lymphedema associated with facial acne rosacea.</ce:simple-para></ce:abstract-sec><ce:abstract-sec><ce:section-title>Design</ce:section-title><ce:simple-para>Two interventional case reports.</ce:simple-para></ce:abstract-sec><ce:abstract-sec><ce:section-title>Methods and intervention</ce:section-title><ce:simple-para>The clinical diagnosis of acne rosacea was based on the physical examination and confirmed by the histopathologic findings obtained from biopsy of the involved tissue. Surgical treatment was required to address the disfiguring chronic eyelid lymphedema and to correct the resultant mechanical lower eyelid ectropion in both patients.</ce:simple-para></ce:abstract-sec><ce:abstract-sec><ce:section-title>Results</ce:section-title><ce:simple-para>Surgical debulking of the affected soft tissue resulted in very satisfactory cosmetic and functional improvement in both patients.</ce:simple-para></ce:abstract-sec><ce:abstract-sec><ce:section-title>Conclusions</ce:section-title><ce:simple-para>To our knowledge, this is the first series of cases of chronic eyelid lymphedema secondary to acne rosacea reported in the ophthalmic literature. Six similar cases have been described previously in the dermatologic literature; all of which had been treated medically without satisfactory results. Surgical debulking of the involved eyelids should be considered in patients affected by persistent symptomatic rosacea lymphedema.</ce:simple-para></ce:abstract-sec></ce:abstract></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Chronic eyelid lymphedema and acne rosacea</title><subTitle>Report of two cases</subTitle></titleInfo><titleInfo type="alternative" lang="en" contentType="CDATA"><title>Chronic eyelid lymphedema and acne rosacea</title><subTitle>Report of two cases</subTitle></titleInfo><name type="personal"><namePart type="given">Francesco P</namePart><namePart type="family">Bernardini</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Ophthalmology Clinic, S. Martino Hospital, University of Genova School of Medicine, Genova, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Robert C</namePart><namePart type="family">Kersten</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</affiliation><description>Reprints requests to Robert C. Kersten, MD, The University of Cincinnati Medical Center, The Barrett Center, P.O. Box 670670, Cincinnati, OH 45267-0670</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Lucie M</namePart><namePart type="family">Khouri</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Muhammad</namePart><namePart type="family">Moin</namePart><description>FRCOphth</description><affiliation>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Dwight R</namePart><namePart type="family">Kulwin</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>The Barrett Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Diya F</namePart><namePart type="family">Mutasim</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Dermatology, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article"></genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">2000</dateIssued><copyrightDate encoding="w3cdtf">2000</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">Objective The authors describe the clinical findings and surgical treatment of two patients affected by chronic eyelid lymphedema associated with facial acne rosacea.Design Two interventional case reports.Methods and intervention The clinical diagnosis of acne rosacea was based on the physical examination and confirmed by the histopathologic findings obtained from biopsy of the involved tissue. Surgical treatment was required to address the disfiguring chronic eyelid lymphedema and to correct the resultant mechanical lower eyelid ectropion in both patients.Results Surgical debulking of the affected soft tissue resulted in very satisfactory cosmetic and functional improvement in both patients.Conclusions To our knowledge, this is the first series of cases of chronic eyelid lymphedema secondary to acne rosacea reported in the ophthalmic literature. Six similar cases have been described previously in the dermatologic literature; all of which had been treated medically without satisfactory results. Surgical debulking of the involved eyelids should be considered in patients affected by persistent symptomatic rosacea lymphedema.</abstract><note>Manuscript no. 99748.</note><note type="content">Figure 1: Chronic lymphedema affecting both lower eyelids and left upper eyelid. The figure shows marked erythema of the involved eyelids and scattered teleangectasias of upper cheeks.</note><note type="content">Figure 2: Histologic examination of the excision specimen from patient 1 reveals dilated lymphatic channels and lymphocytic infiltrate (arrow; stain, hematoxylin–eosin; original magnification ×100).</note><note type="content">Figure 3: Chronic lymphedema affecting the right lower eyelid. The figure shows marked erythema and teleangectasias of the skin overlying eyelids and upper cheeks.</note><note type="content">Figure 4: Patient 1 after debulking and horizontal tightening (3 weeks after surgery).</note><note type="content">Figure 5: Patient 2 after debulking and horizontal tightening (2 weeks after surgery).</note><note type="content">Table 1: Differential Diagnosis of Chronic Facial Edema legend</note><relatedItem type="host"><titleInfo><title>Ophthalmology</title></titleInfo><titleInfo type="abbreviated"><title>OPHTHA</title></titleInfo><genre type="journal">journal</genre><originInfo><dateIssued encoding="w3cdtf">200012</dateIssued></originInfo><identifier type="ISSN">0161-6420</identifier><identifier type="PII">S0161-6420(00)X0013-9</identifier><part><date>200012</date><detail type="volume"><number>107</number><caption>vol.</caption></detail><detail type="issue"><number>12</number><caption>no.</caption></detail><extent unit="issue pages"><start>A1</start><end>A34</end></extent><extent unit="issue pages"><start>2115</start><end>2432</end></extent><extent unit="pages"><start>2220</start><end>2223</end></extent></part></relatedItem><identifier type="istex">4E4972AC96A9721D78234B5429F26575F1B99CAD</identifier><identifier type="DOI">10.1016/S0161-6420(00)00429-2</identifier><identifier type="PII">S0161-6420(00)00429-2</identifier><accessCondition type="use and reproduction" contentType="copyright">©2000 American Academy of Ophthalmology, Inc.</accessCondition><recordInfo><recordContentSource>ELSEVIER</recordContentSource><recordOrigin>American Academy of Ophthalmology, Inc., ©2000</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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