Management of leg ulcers in patients with chronic venous insufficiency: the experience of a Dermatology Clinic in Bucharest, Romania
Identifieur interne : 001B27 ( Istex/Corpus ); précédent : 001B26; suivant : 001B28Management of leg ulcers in patients with chronic venous insufficiency: the experience of a Dermatology Clinic in Bucharest, Romania
Auteurs : C. M. Salavastru ; L. E. Nedelcu ; G-S. IplicaSource :
- Dermatologic Therapy [ 1396-0296 ] ; 2012-07.
Abstract
Venous ulcers are the most severe skin manifestation of chronic venous insufficiency. Treatment is complex and it is performed according to the stage of the disease. It includes changes of lifestyle, compressive therapy, phlebotropic medication, topical therapy of the ulcer, antibiotic therapy (topical and systemic), sclerotherapy, and surgical treatment. Patients with venous leg ulcers that attend the Second Dermatology Clinic of Colentina Clinical Hospital, are treated both as inpatients and as outpatients. They benefit from topical treatment and bandaging performed by specialized medical personnel in separate treatment room with strictly monitored conditions of asepsis and antisepsis. A follow‐up study of these patients was made from January 1, 2009 to December 31, 2011. The average age of patients was 65.9 years (± 14.2), most of them being in the eight decade of life (31.9%). In almost half of the cases (44.2%), the patients spent more than 1 week in the hospital. Bacteriological investigations from the ulcers were performed in 55.1% of patients and the most frequent infectious agents were found to be Staphylococcus aureus (26.3%) and Enterobacter spp. (17.2%). Treatment of leg ulcer patients proves to be a long and complex one, a systematic and organized approach being needed in order to obtain healing of the wound.
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DOI: 10.1111/j.1529-8019.2012.01513.x
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Iplica</name><affiliation><mods:affiliation>2nd Clinic of Dermatology, Colentina Clinical Hospital, Bucharest, Romania</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: tiplica@upcmail.ro</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:3BD5E097A2817706138F0801DAEF9037A9070B46</idno><date when="2012" year="2012">2012</date><idno type="doi">10.1111/j.1529-8019.2012.01513.x</idno><idno type="url">https://api.istex.fr/document/3BD5E097A2817706138F0801DAEF9037A9070B46/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001B27</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001B27</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Management of leg ulcers in patients with chronic venous insufficiency: the experience of a <hi rend="fc">D</hi>ermatology <hi rend="fc">C</hi>linic in <hi rend="fc">B</hi>ucharest, <hi rend="fc">R</hi>omania</title><author><name sortKey="Salavastru, C M" sort="Salavastru, C M" uniqKey="Salavastru C" first="C. M." last="Salavastru">C. M. Salavastru</name><affiliation><mods:affiliation>2nd Clinic of Dermatology, Colentina Clinical Hospital, Bucharest, Romania</mods:affiliation></affiliation></author><author><name sortKey="Nedelcu, L E" sort="Nedelcu, L E" uniqKey="Nedelcu L" first="L. E." last="Nedelcu">L. E. Nedelcu</name><affiliation><mods:affiliation>2nd Clinic of Dermatology, Colentina Clinical Hospital, Bucharest, Romania</mods:affiliation></affiliation></author><author><name sortKey=" Iplica, G" sort=" Iplica, G" uniqKey=" Iplica G" first="G-S." last=" Iplica">G-S. Iplica</name><affiliation><mods:affiliation>2nd Clinic of Dermatology, Colentina Clinical Hospital, Bucharest, Romania</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: tiplica@upcmail.ro</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Dermatologic Therapy</title><title level="j" type="sub">Evaluation and Treatment of Vascular Disorders</title><title level="j" type="alt">DERMATOLOGIC THERAPY</title><idno type="ISSN">1396-0296</idno><idno type="eISSN">1529-8019</idno><imprint><biblScope unit="vol">25</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="304">304</biblScope><biblScope unit="page" to="313">313</biblScope><biblScope unit="page-count">10</biblScope><date type="published" when="2012-07">2012-07</date></imprint><idno type="ISSN">1396-0296</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1396-0296</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">Venous ulcers are the most severe skin manifestation of chronic venous insufficiency. Treatment is complex and it is performed according to the stage of the disease. It includes changes of lifestyle, compressive therapy, phlebotropic medication, topical therapy of the ulcer, antibiotic therapy (topical and systemic), sclerotherapy, and surgical treatment. Patients with venous leg ulcers that attend the Second Dermatology Clinic of Colentina Clinical Hospital, are treated both as inpatients and as outpatients. They benefit from topical treatment and bandaging performed by specialized medical personnel in separate treatment room with strictly monitored conditions of asepsis and antisepsis. A follow‐up study of these patients was made from January 1, 2009 to December 31, 2011. The average age of patients was 65.9 years (± 14.2), most of them being in the eight decade of life (31.9%). In almost half of the cases (44.2%), the patients spent more than 1 week in the hospital. Bacteriological investigations from the ulcers were performed in 55.1% of patients and the most frequent infectious agents were found to be Staphylococcus aureus (26.3%) and Enterobacter spp. (17.2%). Treatment of leg ulcer patients proves to be a long and complex one, a systematic and organized approach being needed in order to obtain healing of the wound.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>venous</json:string><json:string>dermatitis</json:string><json:string>venous ulcers</json:string><json:string>chronic venous</json:string><json:string>antibiotic</json:string><json:string>dermatologist</json:string><json:string>romania</json:string><json:string>debridement</json:string><json:string>ulcer</json:string><json:string>antiinfectious</json:string><json:string>dermatology</json:string><json:string>hydrocolloid</json:string><json:string>vaseline</json:string><json:string>topical treatment</json:string><json:string>bacteriological</json:string><json:string>salavastru</json:string><json:string>phlebotropic</json:string><json:string>bucharest</json:string><json:string>lower limbs</json:string><json:string>phlebotropic medication</json:string><json:string>surgical treatment</json:string><json:string>clinic</json:string><json:string>surgical</json:string><json:string>ulcer patients</json:string><json:string>venous system</json:string><json:string>boric acid</json:string><json:string>lesion</json:string><json:string>topical</json:string><json:string>healing process</json:string><json:string>diabetes mellitus</json:string><json:string>brin deposits</json:string><json:string>perilesional dermatitis</json:string><json:string>clinical aspect</json:string><json:string>venous disease</json:string><json:string>study period</json:string><json:string>local therapy</json:string><json:string>ulcer development</json:string><json:string>hospital pharmacy</json:string><json:string>venous ulcer</json:string><json:string>medication</json:string><json:string>adverse reactions</json:string><json:string>antibiotic therapy</json:string><json:string>second clinic</json:string><json:string>staphylococcus aureus</json:string><json:string>hydrocolloid dressings</json:string><json:string>pain management</json:string><json:string>nonsteroidal drugs</json:string><json:string>topical anesthetics</json:string><json:string>surgery clinics</json:string><json:string>compressive therapy</json:string><json:string>statistical analysis</json:string><json:string>contact dermatitis</json:string><json:string>blood tests</json:string><json:string>total number</json:string><json:string>therapy methods</json:string><json:string>antiinfectious therapy</json:string><json:string>study group</json:string><json:string>irritant contact dermatitis</json:string><json:string>gentian violet</json:string><json:string>silver nitrate</json:string><json:string>diabetic patients</json:string><json:string>varicose veins</json:string><json:string>trophic changes</json:string><json:string>boric acid solution</json:string><json:string>hydrogen peroxide</json:string><json:string>necrotic tissues</json:string><json:string>immunological conditions</json:string><json:string>topical antibiotics</json:string><json:string>ulcer healing</json:string><json:string>fusidic acid</json:string><json:string>topical therapy</json:string><json:string>zinc oxide</json:string><json:string>heart failure</json:string><json:string>topical corticoids</json:string><json:string>hydrocortisone acetate</json:string><json:string>venous blood</json:string><json:string>venous stasis</json:string><json:string>elastic contention</json:string><json:string>chronic venous disease</json:string><json:string>american college</json:string><json:string>side effects</json:string><json:string>therapy</json:string><json:string>systemic</json:string></teeft></keywords><author><json:item><name>C. 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It includes changes of lifestyle, compressive therapy, phlebotropic medication, topical therapy of the ulcer, antibiotic therapy (topical and systemic), sclerotherapy, and surgical treatment. Patients with venous leg ulcers that attend the Second Dermatology Clinic of Colentina Clinical Hospital, are treated both as inpatients and as outpatients. They benefit from topical treatment and bandaging performed by specialized medical personnel in separate treatment room with strictly monitored conditions of asepsis and antisepsis. A follow‐up study of these patients was made from January 1, 2009 to December 31, 2011. The average age of patients was 65.9 years (± 14.2), most of them being in the eight decade of life (31.9%). In almost half of the cases (44.2%), the patients spent more than 1 week in the hospital. Bacteriological investigations from the ulcers were performed in 55.1% of patients and the most frequent infectious agents were found to be Staphylococcus aureus (26.3%) and Enterobacter spp. (17.2%). Treatment of leg ulcer patients proves to be a long and complex one, a systematic and organized approach being needed in order to obtain healing of the wound.</abstract><qualityIndicators><score>7.472</score><pdfVersion>1.3</pdfVersion><pdfPageSize>595.276 x 782.362 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>1343</abstractCharCount><pdfWordCount>5296</pdfWordCount><pdfCharCount>34560</pdfCharCount><pdfPageCount>10</pdfPageCount><abstractWordCount>206</abstractWordCount></qualityIndicators><title>Management of leg ulcers in patients with chronic venous insufficiency: the experience of a Dermatology Clinic in Bucharest, Romania</title><genre><json:string>article</json:string></genre><host><title>Dermatologic Therapy</title><language><json:string>unknown</json:string></language><doi><json:string>10.1111/(ISSN)1529-8019</json:string></doi><issn><json:string>1396-0296</json:string></issn><eissn><json:string>1529-8019</json:string></eissn><publisherId><json:string>DTH</json:string></publisherId><volume>25</volume><issue>4</issue><pages><first>304</first><last>313</last><total>10</total></pages><genre><json:string>journal</json:string></genre><subject><json:item><value>Original Article</value></json:item></subject></host><categories><wos><json:string>science</json:string><json:string>dermatology</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>clinical medicine</json:string><json:string>dermatology & venereal diseases</json:string></scienceMetrix></categories><publicationDate>2012</publicationDate><copyrightDate>2012</copyrightDate><doi><json:string>10.1111/j.1529-8019.2012.01513.x</json:string></doi><id>3BD5E097A2817706138F0801DAEF9037A9070B46</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/3BD5E097A2817706138F0801DAEF9037A9070B46/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/3BD5E097A2817706138F0801DAEF9037A9070B46/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/3BD5E097A2817706138F0801DAEF9037A9070B46/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main">Management of leg ulcers in patients with chronic venous insufficiency: the experience of a <hi rend="fc">D</hi>ermatology <hi rend="fc">C</hi>linic in <hi rend="fc">B</hi>ucharest, <hi rend="fc">R</hi>omania</title></titleStmt><publicationStmt><publisher>Blackwell Publishing Ltd</publisher><availability><licence>© 2012 Wiley Periodicals, Inc.</licence></availability><date type="published" when="2012-07"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main">Management of leg ulcers in patients with chronic venous insufficiency: the experience of a <hi rend="fc">D</hi>ermatology <hi rend="fc">C</hi>linic in <hi rend="fc">B</hi>ucharest, <hi rend="fc">R</hi>omania</title><title level="a" type="short">Management of leg ulcers in Bucharest, Romania</title><author xml:id="author-0000"><persName><forename type="first">C. M.</forename><surname>Salavastru</surname></persName><affiliation><orgName>2nd Clinic of Dermatology</orgName><orgName>Colentina Clinical Hospital</orgName><address><settlement type="city">Bucharest</settlement><country key="RO">Romania</country></address></affiliation></author><author xml:id="author-0001"><persName><forename type="first">L. E.</forename><surname>Nedelcu</surname></persName><affiliation><orgName>2nd Clinic of Dermatology</orgName><orgName>Colentina Clinical Hospital</orgName><address><settlement type="city">Bucharest</settlement><country key="RO">Romania</country></address></affiliation></author><author xml:id="author-0002" role="corresp"><persName><forename type="first">G‐S.</forename><surname>Ţiplica</surname></persName><affiliation><orgName>2nd Clinic of Dermatology</orgName><orgName>Colentina Clinical Hospital</orgName><address><settlement type="city">Bucharest</settlement><country key="RO">Romania</country></address></affiliation><affiliation>Address correspondence and reprint requests to: George‐Sorin Ţiplica, MD, PhD, Professor, Head of Clinic, 2nd Clinic of Dermatology, Colentina Clinical Hospital, 19‐21 Stefan cel Mare Street, sector 2, Bucharest 020125, Romania, or email: tiplica@upcmail.ro.</affiliation></author><idno type="istex">3BD5E097A2817706138F0801DAEF9037A9070B46</idno><idno type="DOI">10.1111/j.1529-8019.2012.01513.x</idno><idno type="unit">DTH1513</idno><idno type="toTypesetVersion">file:DTH.DTH1513.pdf</idno></analytic><monogr><title level="j" type="main">Dermatologic Therapy</title><title level="j" type="sub">Evaluation and Treatment of Vascular Disorders</title><title level="j" type="alt">DERMATOLOGIC THERAPY</title><idno type="pISSN">1396-0296</idno><idno type="eISSN">1529-8019</idno><idno type="book-DOI">10.1111/(ISSN)1529-8019</idno><idno type="book-part-DOI">10.1111/dth.2012.25.issue-4</idno><idno type="product">DTH</idno><imprint><biblScope unit="vol">25</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="304">304</biblScope><biblScope unit="page" to="313">313</biblScope><biblScope unit="page-count">10</biblScope><date type="published" when="2012-07"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract style="main"><head>Abstract</head><p>Venous ulcers are the most severe skin manifestation of chronic venous insufficiency. Treatment is complex and it is performed according to the stage of the disease. It includes changes of lifestyle, compressive therapy, phlebotropic medication, topical therapy of the ulcer, antibiotic therapy (topical and systemic), sclerotherapy, and surgical treatment. Patients with venous leg ulcers that attend the <hi rend="fc">S</hi>econd <hi rend="fc">D</hi>ermatology <hi rend="fc">C</hi>linic of <hi rend="fc">C</hi>olentina <hi rend="fc">C</hi>linical <hi rend="fc">H</hi>ospital, are treated both as inpatients and as outpatients. They benefit from topical treatment and bandaging performed by specialized medical personnel in separate treatment room with strictly monitored conditions of asepsis and antisepsis. A follow‐up study of these patients was made from <hi rend="fc">J</hi>anuary 1, 2009 to <hi rend="fc">D</hi>ecember 31, 2011. The average age of patients was 65.9 years (± 14.2), most of them being in the eight decade of life (31.9%). In almost half of the cases (44.2%), the patients spent more than 1 week in the hospital. Bacteriological investigations from the ulcers were performed in 55.1% of patients and the most frequent infectious agents were found to be <hi rend="italic"><hi rend="fc">S</hi>taphylococcus aureus</hi> (26.3%) and <hi rend="italic"><hi rend="fc">E</hi>nterobacter spp</hi>. (17.2%). Treatment of leg ulcer patients proves to be a long and complex one, a systematic and organized approach being needed in order to obtain healing of the wound.</p></abstract><textClass><keywords><term xml:id="dth1513-kwd-0001">chronic venous insufficiency</term><term xml:id="dth1513-kwd-0002">debridement</term><term xml:id="dth1513-kwd-0003">leg ulcer</term></keywords><classCode scheme="tocHeading1">Original Articles</classCode><classCode scheme="articleCategory">Original Article</classCode></textClass><langUsage><language ident="EN"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/3BD5E097A2817706138F0801DAEF9037A9070B46/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body" wicri:toSee="Element #text"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component type="serialArticle" version="2.0" xml:id="dth1513" xml:lang="en"><header><publicationMeta level="product"><doi origin="wiley">10.1111/(ISSN)1529-8019</doi><issn type="print">1396-0296</issn><issn type="electronic">1529-8019</issn><idGroup><id type="product" value="DTH"></id></idGroup><titleGroup><title sort="DERMATOLOGIC THERAPY" type="main">Dermatologic Therapy</title><title type="short">Dermatol Ther</title></titleGroup></publicationMeta><publicationMeta level="part" position="07104"><doi origin="wiley">10.1111/dth.2012.25.issue-4</doi><titleGroup><title type="specialIssueTitle">Evaluation and Treatment of Vascular Disorders</title></titleGroup><copyright ownership="publisher">© 2012 Wiley Periodicals, Inc.</copyright><numberingGroup><numbering number="25" type="journalVolume">25</numbering><numbering type="journalIssue">4</numbering></numberingGroup><coverDate startDate="2012-07">July/August 2012</coverDate></publicationMeta><publicationMeta level="unit" position="40" status="forIssue" type="article"><doi>10.1111/j.1529-8019.2012.01513.x</doi><idGroup><id type="unit" value="DTH1513"></id></idGroup><countGroup><count number="10" type="pageTotal"></count></countGroup><titleGroup><title type="tocHeading1">Original Articles</title><title type="articleCategory">Original Article</title></titleGroup><copyright ownership="publisher">© 2012 Wiley Periodicals, Inc.</copyright><eventGroup><event agent="bestset" date="2012-07-17" type="xmlCreated"></event><event type="firstOnline" date="2012-09-05"></event><event type="publishedOnlineFinalForm" date="2012-09-05"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-17"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.3.4 mode:FullText" date="2015-02-25"></event></eventGroup><numberingGroup><numbering type="pageFirst">304</numbering><numbering type="pageLast">313</numbering></numberingGroup><correspondenceTo>Address correspondence and reprint requests to: George‐Sorin Ţiplica, MD, PhD, Professor, Head of Clinic, 2nd Clinic of Dermatology, Colentina Clinical Hospital, 19‐21 Stefan cel Mare Street, sector 2, Bucharest 020125, Romania, or email: <email>tiplica@upcmail.ro</email>.</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:DTH.DTH1513.pdf"></link></linkGroup></publicationMeta><contentMeta><titleGroup><title type="short">Management of leg ulcers in Bucharest, <fc>R</fc>omania</title><title type="shortAuthors"><fc>S</fc>alavastru et al.</title><title type="main">Management of leg ulcers in patients with chronic venous insufficiency: the experience of a <fc>D</fc>ermatology <fc>C</fc>linic in <fc>B</fc>ucharest, <fc>R</fc>omania</title></titleGroup><creators><creator affiliationRef="#dth1513-aff-0001" creatorRole="author" xml:id="dth1513-cr-0001"><personName><givenNames>C. M.</givenNames><familyName>Salavastru</familyName></personName></creator><creator affiliationRef="#dth1513-aff-0001" creatorRole="author" xml:id="dth1513-cr-0002"><personName><givenNames>L. E.</givenNames><familyName>Nedelcu</familyName></personName></creator><creator affiliationRef="#dth1513-aff-0001" corresponding="yes" creatorRole="author" xml:id="dth1513-cr-0003"><personName><givenNames>G‐S.</givenNames><familyName>Ţiplica</familyName></personName></creator></creators><affiliationGroup><affiliation countryCode="RO" xml:id="dth1513-aff-0001"><orgDiv>2nd Clinic of Dermatology</orgDiv><orgName>Colentina Clinical Hospital</orgName><address><city>Bucharest</city><country>Romania</country></address></affiliation></affiliationGroup><keywordGroup type="author"><keyword xml:id="dth1513-kwd-0001">chronic venous insufficiency</keyword><keyword xml:id="dth1513-kwd-0002">debridement</keyword><keyword xml:id="dth1513-kwd-0003">leg ulcer</keyword></keywordGroup><abstractGroup><abstract type="main"><title type="main">Abstract</title><p>Venous ulcers are the most severe skin manifestation of chronic venous insufficiency. Treatment is complex and it is performed according to the stage of the disease. It includes changes of lifestyle, compressive therapy, phlebotropic medication, topical therapy of the ulcer, antibiotic therapy (topical and systemic), sclerotherapy, and surgical treatment. Patients with venous leg ulcers that attend the <fc>S</fc>econd <fc>D</fc>ermatology <fc>C</fc>linic of <fc>C</fc>olentina <fc>C</fc>linical <fc>H</fc>ospital, are treated both as inpatients and as outpatients. They benefit from topical treatment and bandaging performed by specialized medical personnel in separate treatment room with strictly monitored conditions of asepsis and antisepsis. A follow‐up study of these patients was made from <fc>J</fc>anuary 1, 2009 to <fc>D</fc>ecember 31, 2011. The average age of patients was 65.9 years (± 14.2), most of them being in the eight decade of life (31.9%). In almost half of the cases (44.2%), the patients spent more than 1 week in the hospital. Bacteriological investigations from the ulcers were performed in 55.1% of patients and the most frequent infectious agents were found to be <i><fc>S</fc>taphylococcus aureus</i> (26.3%) and <i><fc>E</fc>nterobacter spp</i>. (17.2%). Treatment of leg ulcer patients proves to be a long and complex one, a systematic and organized approach being needed in order to obtain healing of the wound.</p></abstract></abstractGroup></contentMeta></header> </component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Management of leg ulcers in patients with chronic venous insufficiency: the experience of a Dermatology Clinic in Bucharest, Romania</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Management of leg ulcers in Bucharest, Romania</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Management of leg ulcers in patients with chronic venous insufficiency: the experience of a Dermatology Clinic in Bucharest, Romania</title></titleInfo><name type="personal"><namePart type="given">C. M.</namePart><namePart type="family">Salavastru</namePart><affiliation>2nd Clinic of Dermatology, Colentina Clinical Hospital, Bucharest, Romania</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L. E.</namePart><namePart type="family">Nedelcu</namePart><affiliation>2nd Clinic of Dermatology, Colentina Clinical Hospital, Bucharest, Romania</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G‐S.</namePart><namePart type="family">Ţiplica</namePart><affiliation>2nd Clinic of Dermatology, Colentina Clinical Hospital, Bucharest, Romania</affiliation><affiliation>E-mail: tiplica@upcmail.ro</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><dateIssued encoding="w3cdtf">2012-07</dateIssued><dateCreated encoding="w3cdtf">2012-07-17</dateCreated><copyrightDate encoding="w3cdtf">2012</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract>Venous ulcers are the most severe skin manifestation of chronic venous insufficiency. Treatment is complex and it is performed according to the stage of the disease. It includes changes of lifestyle, compressive therapy, phlebotropic medication, topical therapy of the ulcer, antibiotic therapy (topical and systemic), sclerotherapy, and surgical treatment. Patients with venous leg ulcers that attend the Second Dermatology Clinic of Colentina Clinical Hospital, are treated both as inpatients and as outpatients. They benefit from topical treatment and bandaging performed by specialized medical personnel in separate treatment room with strictly monitored conditions of asepsis and antisepsis. A follow‐up study of these patients was made from January 1, 2009 to December 31, 2011. The average age of patients was 65.9 years (± 14.2), most of them being in the eight decade of life (31.9%). In almost half of the cases (44.2%), the patients spent more than 1 week in the hospital. Bacteriological investigations from the ulcers were performed in 55.1% of patients and the most frequent infectious agents were found to be Staphylococcus aureus (26.3%) and Enterobacter spp. (17.2%). Treatment of leg ulcer patients proves to be a long and complex one, a systematic and organized approach being needed in order to obtain healing of the wound.</abstract><subject><genre>keywords</genre><topic>chronic venous insufficiency</topic><topic>debridement</topic><topic>leg ulcer</topic></subject><relatedItem type="host"><titleInfo><title>Dermatologic Therapy</title></titleInfo><titleInfo type="abbreviated"><title>Dermatol Ther</title></titleInfo><genre type="journal">journal</genre><subject><genre>article-category</genre><topic>Original Article</topic></subject><identifier type="ISSN">1396-0296</identifier><identifier type="eISSN">1529-8019</identifier><identifier type="DOI">10.1111/(ISSN)1529-8019</identifier><identifier type="PublisherID">DTH</identifier><part><date>2012</date><detail type="title"><title>Evaluation and Treatment of Vascular Disorders</title></detail><detail type="volume"><caption>vol.</caption><number>25</number></detail><detail type="issue"><caption>no.</caption><number>4</number></detail><extent unit="pages"><start>304</start><end>313</end><total>10</total></extent></part></relatedItem><identifier type="istex">3BD5E097A2817706138F0801DAEF9037A9070B46</identifier><identifier type="DOI">10.1111/j.1529-8019.2012.01513.x</identifier><identifier type="ArticleID">DTH1513</identifier><accessCondition type="use and reproduction" contentType="copyright">© 2012 Wiley Periodicals, Inc.© 2012 Wiley Periodicals, Inc.</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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