Estimation of body water compartments in cirrhosis by multiple-frequency bioelectrical-impedance analysis
Identifieur interne : 001772 ( Istex/Corpus ); précédent : 001771; suivant : 001773Estimation of body water compartments in cirrhosis by multiple-frequency bioelectrical-impedance analysis
Auteurs : Megan E. Lehnert ; David D. Clarke ; John G. Gibbons ; Leigh C. Ward ; Sue M. Golding ; Ross W. Shepherd ; Bruce H. Cornish ; Darrell H. G CrawfordSource :
- Nutrition [ 0899-9007 ] ; 2001.
English descriptors
Abstract
Estimation of total body water by measuring bioelectrical impedance at a fixed frequency of 50 kHz is useful in assessing body composition in healthy populations. However, in cirrhosis, the distribution of total body water between the extracellular and intracellular compartments is of greater clinical importance. We report an evaluation of a new multiple-frequency bioelectrical-impedance analysis technique (MFBIA) that may quantify the distribution of total body water in cirrhosis. In 21 cirrhotic patients and 21 healthy control subjects, impedance to the flow of current was measured at frequencies ranging from 4 to 1012 kHz. These measurements were used to estimate body water compartments and then compared with total body water and extracellular water determined by isotope methodology. In cirrhotic patients, extracellular water and total body water (as determined by isotope methods) were well predicted by MFBIA (r = 0.73 and 0.89, respectively). However, the 95% confidence intervals of the limits of agreement between MFBIA and the isotope methods were ±14% and ±9% for cirrhotics (extracellular water and total body water, respectively) and ±9% and ±9% for cirrhotics without ascites. The 95% confidence intervals estimated from the control group were ±10% and ±5% for extracellular water and total body water, respectively. Thus, despite strong correlations between MFBIA and isotope measurements, the relatively large limits of agreement with accepted techniques suggest that the MFBIA technique requires further refinement before it can be routinely used to determine the nutritional assessment of individual cirrhotic patients.
Url:
DOI: 10.1016/S0899-9007(00)00473-1
Links to Exploration step
ISTEX:337CBBCDCCF76CEA6956402C42148BB26393E629Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Estimation of body water compartments in cirrhosis by multiple-frequency bioelectrical-impedance analysis</title><author><name sortKey="Lehnert, Megan E" sort="Lehnert, Megan E" uniqKey="Lehnert M" first="Megan E" last="Lehnert">Megan E. Lehnert</name><affiliation><mods:affiliation>Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia</mods:affiliation></affiliation></author><author><name sortKey="Clarke, David D" sort="Clarke, David D" uniqKey="Clarke D" first="David D" last="Clarke">David D. Clarke</name><affiliation><mods:affiliation>Department of Child Health, University of Queensland, Brisbane, Queensland, Australia</mods:affiliation></affiliation></author><author><name sortKey="Gibbons, John G" sort="Gibbons, John G" uniqKey="Gibbons J" first="John G" last="Gibbons">John G. Gibbons</name><affiliation><mods:affiliation>Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia</mods:affiliation></affiliation></author><author><name sortKey="Ward, Leigh C" sort="Ward, Leigh C" uniqKey="Ward L" first="Leigh C" last="Ward">Leigh C. Ward</name><affiliation><mods:affiliation>Department of Biochemistry, University of Queensland, Brisbane, Queensland, Australia</mods:affiliation></affiliation></author><author><name sortKey="Golding, Sue M" sort="Golding, Sue M" uniqKey="Golding S" first="Sue M" last="Golding">Sue M. Golding</name><affiliation><mods:affiliation>Department of Earth Sciences, University of Queensland, Brisbane, Queensland, Australia</mods:affiliation></affiliation></author><author><name sortKey="Shepherd, Ross W" sort="Shepherd, Ross W" uniqKey="Shepherd R" first="Ross W" last="Shepherd">Ross W. Shepherd</name><affiliation><mods:affiliation>Department of Child Health, University of Queensland, Brisbane, Queensland, Australia</mods:affiliation></affiliation></author><author><name sortKey="Cornish, Bruce H" sort="Cornish, Bruce H" uniqKey="Cornish B" first="Bruce H" last="Cornish">Bruce H. Cornish</name><affiliation><mods:affiliation>School of Physics, Queensland University of Technology, Brisbane, Queensland, Australia</mods:affiliation></affiliation></author><author><name sortKey="Crawford, Darrell H G" sort="Crawford, Darrell H G" uniqKey="Crawford D" first="Darrell H. G" last="Crawford">Darrell H. G Crawford</name><affiliation><mods:affiliation>Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:337CBBCDCCF76CEA6956402C42148BB26393E629</idno><date when="2001" year="2001">2001</date><idno type="doi">10.1016/S0899-9007(00)00473-1</idno><idno type="url">https://api.istex.fr/document/337CBBCDCCF76CEA6956402C42148BB26393E629/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001772</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001772</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Estimation of body water compartments in cirrhosis by multiple-frequency bioelectrical-impedance analysis</title><author><name sortKey="Lehnert, Megan E" sort="Lehnert, Megan E" uniqKey="Lehnert M" first="Megan E" last="Lehnert">Megan E. Lehnert</name><affiliation><mods:affiliation>Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia</mods:affiliation></affiliation></author><author><name sortKey="Clarke, David D" sort="Clarke, David D" uniqKey="Clarke D" first="David D" last="Clarke">David D. Clarke</name><affiliation><mods:affiliation>Department of Child Health, University of Queensland, Brisbane, Queensland, Australia</mods:affiliation></affiliation></author><author><name sortKey="Gibbons, John G" sort="Gibbons, John G" uniqKey="Gibbons J" first="John G" last="Gibbons">John G. Gibbons</name><affiliation><mods:affiliation>Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia</mods:affiliation></affiliation></author><author><name sortKey="Ward, Leigh C" sort="Ward, Leigh C" uniqKey="Ward L" first="Leigh C" last="Ward">Leigh C. Ward</name><affiliation><mods:affiliation>Department of Biochemistry, University of Queensland, Brisbane, Queensland, Australia</mods:affiliation></affiliation></author><author><name sortKey="Golding, Sue M" sort="Golding, Sue M" uniqKey="Golding S" first="Sue M" last="Golding">Sue M. Golding</name><affiliation><mods:affiliation>Department of Earth Sciences, University of Queensland, Brisbane, Queensland, Australia</mods:affiliation></affiliation></author><author><name sortKey="Shepherd, Ross W" sort="Shepherd, Ross W" uniqKey="Shepherd R" first="Ross W" last="Shepherd">Ross W. Shepherd</name><affiliation><mods:affiliation>Department of Child Health, University of Queensland, Brisbane, Queensland, Australia</mods:affiliation></affiliation></author><author><name sortKey="Cornish, Bruce H" sort="Cornish, Bruce H" uniqKey="Cornish B" first="Bruce H" last="Cornish">Bruce H. Cornish</name><affiliation><mods:affiliation>School of Physics, Queensland University of Technology, Brisbane, Queensland, Australia</mods:affiliation></affiliation></author><author><name sortKey="Crawford, Darrell H G" sort="Crawford, Darrell H G" uniqKey="Crawford D" first="Darrell H. G" last="Crawford">Darrell H. G Crawford</name><affiliation><mods:affiliation>Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Nutrition</title><title level="j" type="abbrev">NUT</title><idno type="ISSN">0899-9007</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="2001">2001</date><biblScope unit="volume">17</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="31">31</biblScope><biblScope unit="page" to="34">34</biblScope></imprint><idno type="ISSN">0899-9007</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0899-9007</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>ascites</term><term>cirrhosis</term><term>liver</term><term>multiple-frequency bioelectrical impedance</term><term>total body water</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Estimation of total body water by measuring bioelectrical impedance at a fixed frequency of 50 kHz is useful in assessing body composition in healthy populations. However, in cirrhosis, the distribution of total body water between the extracellular and intracellular compartments is of greater clinical importance. We report an evaluation of a new multiple-frequency bioelectrical-impedance analysis technique (MFBIA) that may quantify the distribution of total body water in cirrhosis. In 21 cirrhotic patients and 21 healthy control subjects, impedance to the flow of current was measured at frequencies ranging from 4 to 1012 kHz. These measurements were used to estimate body water compartments and then compared with total body water and extracellular water determined by isotope methodology. In cirrhotic patients, extracellular water and total body water (as determined by isotope methods) were well predicted by MFBIA (r = 0.73 and 0.89, respectively). However, the 95% confidence intervals of the limits of agreement between MFBIA and the isotope methods were ±14% and ±9% for cirrhotics (extracellular water and total body water, respectively) and ±9% and ±9% for cirrhotics without ascites. The 95% confidence intervals estimated from the control group were ±10% and ±5% for extracellular water and total body water, respectively. Thus, despite strong correlations between MFBIA and isotope measurements, the relatively large limits of agreement with accepted techniques suggest that the MFBIA technique requires further refinement before it can be routinely used to determine the nutritional assessment of individual cirrhotic patients.</div></front></TEI><istex><corpusName>elsevier</corpusName><keywords><teeft><json:string>mfbia</json:string><json:string>cirrhotic</json:string><json:string>cirrhosis</json:string><json:string>impedance</json:string><json:string>ascites</json:string><json:string>extracellular</json:string><json:string>total body water</json:string><json:string>cirrhotic patients</json:string><json:string>cirrhotics</json:string><json:string>control subjects</json:string><json:string>isotope</json:string><json:string>extracellular water</json:string><json:string>body water</json:string><json:string>isotope methodology</json:string><json:string>deuterium</json:string><json:string>cirrhotic subjects</json:string><json:string>clin</json:string><json:string>bioelectrical</json:string><json:string>liver disease</json:string><json:string>body water compartments</json:string><json:string>characteristic frequency</json:string><json:string>clin nutr</json:string><json:string>controls cirrhotics cirrhotics</json:string><json:string>isotope methods</json:string><json:string>methodology</json:string><json:string>control group</json:string><json:string>nutrition volume</json:string><json:string>mfbia technique</json:string><json:string>total body potassium</json:string><json:string>body composition</json:string><json:string>chronic liver disease</json:string></teeft></keywords><author><json:item><name>Megan E Lehnert BSc</name><affiliations><json:string>Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia</json:string></affiliations></json:item><json:item><name>David D Clarke MD</name><affiliations><json:string>Department of Child Health, University of Queensland, Brisbane, Queensland, Australia</json:string></affiliations></json:item><json:item><name>John G Gibbons</name><affiliations><json:string>Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia</json:string></affiliations></json:item><json:item><name>Leigh C Ward PhD</name><affiliations><json:string>Department of Biochemistry, University of Queensland, Brisbane, Queensland, Australia</json:string></affiliations></json:item><json:item><name>Sue M Golding PhD</name><affiliations><json:string>Department of Earth Sciences, University of Queensland, Brisbane, Queensland, Australia</json:string></affiliations></json:item><json:item><name>Ross W Shepherd MD</name><affiliations><json:string>Department of Child Health, University of Queensland, Brisbane, Queensland, Australia</json:string></affiliations></json:item><json:item><name>Bruce H Cornish PhD</name><affiliations><json:string>School of Physics, Queensland University of Technology, Brisbane, Queensland, Australia</json:string></affiliations></json:item><json:item><name>Darrell H.G Crawford MD</name><affiliations><json:string>Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Applied nutritional investigation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>multiple-frequency bioelectrical impedance</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>cirrhosis</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>ascites</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>total body water</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>liver</value></json:item></subject><language><json:string>eng</json:string></language><originalGenre><json:string>Full-length article</json:string></originalGenre><abstract>Estimation of total body water by measuring bioelectrical impedance at a fixed frequency of 50 kHz is useful in assessing body composition in healthy populations. However, in cirrhosis, the distribution of total body water between the extracellular and intracellular compartments is of greater clinical importance. We report an evaluation of a new multiple-frequency bioelectrical-impedance analysis technique (MFBIA) that may quantify the distribution of total body water in cirrhosis. In 21 cirrhotic patients and 21 healthy control subjects, impedance to the flow of current was measured at frequencies ranging from 4 to 1012 kHz. These measurements were used to estimate body water compartments and then compared with total body water and extracellular water determined by isotope methodology. In cirrhotic patients, extracellular water and total body water (as determined by isotope methods) were well predicted by MFBIA (r = 0.73 and 0.89, respectively). However, the 95% confidence intervals of the limits of agreement between MFBIA and the isotope methods were ±14% and ±9% for cirrhotics (extracellular water and total body water, respectively) and ±9% and ±9% for cirrhotics without ascites. The 95% confidence intervals estimated from the control group were ±10% and ±5% for extracellular water and total body water, respectively. Thus, despite strong correlations between MFBIA and isotope measurements, the relatively large limits of agreement with accepted techniques suggest that the MFBIA technique requires further refinement before it can be routinely used to determine the nutritional assessment of individual cirrhotic patients.</abstract><qualityIndicators><score>6.206</score><pdfVersion>1.2</pdfVersion><pdfPageSize>586 x 785 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>6</keywordCount><abstractCharCount>1648</abstractCharCount><pdfWordCount>3326</pdfWordCount><pdfCharCount>21180</pdfCharCount><pdfPageCount>4</pdfPageCount><abstractWordCount>240</abstractWordCount></qualityIndicators><title>Estimation of body water compartments in cirrhosis by multiple-frequency bioelectrical-impedance analysis</title><pii><json:string>S0899-9007(00)00473-1</json:string></pii><genre><json:string>research-article</json:string></genre><host><title>Nutrition</title><language><json:string>unknown</json:string></language><publicationDate>2001</publicationDate><issn><json:string>0899-9007</json:string></issn><pii><json:string>S0899-9007(00)X0048-2</json:string></pii><volume>17</volume><issue>1</issue><pages><first>31</first><last>34</last></pages><genre><json:string>journal</json:string></genre></host><categories><wos><json:string>science</json:string><json:string>nutrition & dietetics</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>biomedical research</json:string><json:string>nutrition & dietetics</json:string></scienceMetrix><inist><json:string>sciences appliquees, technologies et medecines</json:string><json:string>sciences biologiques et medicales</json:string><json:string>sciences medicales</json:string><json:string>anesthesie. reanimation. transfusion. therapie cellulaire et therapie genique</json:string></inist></categories><publicationDate>2001</publicationDate><copyrightDate>2001</copyrightDate><doi><json:string>10.1016/S0899-9007(00)00473-1</json:string></doi><id>337CBBCDCCF76CEA6956402C42148BB26393E629</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/337CBBCDCCF76CEA6956402C42148BB26393E629/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/337CBBCDCCF76CEA6956402C42148BB26393E629/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/337CBBCDCCF76CEA6956402C42148BB26393E629/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Estimation of body water compartments in cirrhosis by multiple-frequency bioelectrical-impedance analysis</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>ELSEVIER</publisher><availability><p>©2001 Elsevier Science Inc.</p></availability><date>2001</date></publicationStmt><notesStmt><note>This study was supported by the Reginald Ferguson Foundation, Greenslopes Hospital, Brisbane, Australia.</note><note type="content">Section title: Applied nutritional investigation</note><note type="content">Table I: Characteristics of study groupslegend</note><note type="content">TABLE II: Regression Analysis of MFBIA versus Body Water (measured by isotope methodology)legend</note><note type="content">TABLE III: Limits of agreement for MFBIA Versus Body Water (measured by isotope methodology)legend</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Estimation of body water compartments in cirrhosis by multiple-frequency bioelectrical-impedance analysis</title><author xml:id="author-0000"><persName><forename type="first">Megan E</forename><surname>Lehnert</surname></persName><roleName type="degree">BSc</roleName><affiliation>Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia</affiliation></author><author xml:id="author-0001"><persName><forename type="first">David D</forename><surname>Clarke</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Child Health, University of Queensland, Brisbane, Queensland, Australia</affiliation></author><author xml:id="author-0002"><persName><forename type="first">John G</forename><surname>Gibbons</surname></persName><note type="biography">FRACP</note><affiliation>FRACP</affiliation><affiliation>Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia</affiliation></author><author xml:id="author-0003"><persName><forename type="first">Leigh C</forename><surname>Ward</surname></persName><roleName type="degree">PhD</roleName><affiliation>Department of Biochemistry, University of Queensland, Brisbane, Queensland, Australia</affiliation></author><author xml:id="author-0004"><persName><forename type="first">Sue M</forename><surname>Golding</surname></persName><roleName type="degree">PhD</roleName><affiliation>Department of Earth Sciences, University of Queensland, Brisbane, Queensland, Australia</affiliation></author><author xml:id="author-0005"><persName><forename type="first">Ross W</forename><surname>Shepherd</surname></persName><roleName type="degree">MD</roleName><note type="biography">FRACP</note><affiliation>FRACP</affiliation><affiliation>Department of Child Health, University of Queensland, Brisbane, Queensland, Australia</affiliation></author><author xml:id="author-0006"><persName><forename type="first">Bruce H</forename><surname>Cornish</surname></persName><roleName type="degree">PhD</roleName><affiliation>School of Physics, Queensland University of Technology, Brisbane, Queensland, Australia</affiliation></author><author xml:id="author-0007"><persName><forename type="first">Darrell H.G</forename><surname>Crawford</surname></persName><roleName type="degree">MD</roleName><note type="biography">FRACP</note><affiliation>FRACP</affiliation><note type="correspondence"><p>Correspondence to: Darrell H. G. Crawford, MD, FRACP, Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Queensland 4102, Australia</p></note><affiliation>Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia</affiliation></author><idno type="istex">337CBBCDCCF76CEA6956402C42148BB26393E629</idno><idno type="DOI">10.1016/S0899-9007(00)00473-1</idno><idno type="PII">S0899-9007(00)00473-1</idno></analytic><monogr><title level="j">Nutrition</title><title level="j" type="abbrev">NUT</title><idno type="pISSN">0899-9007</idno><idno type="PII">S0899-9007(00)X0048-2</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="2001"></date><biblScope unit="volume">17</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="31">31</biblScope><biblScope unit="page" to="34">34</biblScope></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2001</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Estimation of total body water by measuring bioelectrical impedance at a fixed frequency of 50 kHz is useful in assessing body composition in healthy populations. However, in cirrhosis, the distribution of total body water between the extracellular and intracellular compartments is of greater clinical importance. We report an evaluation of a new multiple-frequency bioelectrical-impedance analysis technique (MFBIA) that may quantify the distribution of total body water in cirrhosis. In 21 cirrhotic patients and 21 healthy control subjects, impedance to the flow of current was measured at frequencies ranging from 4 to 1012 kHz. These measurements were used to estimate body water compartments and then compared with total body water and extracellular water determined by isotope methodology. In cirrhotic patients, extracellular water and total body water (as determined by isotope methods) were well predicted by MFBIA (r = 0.73 and 0.89, respectively). However, the 95% confidence intervals of the limits of agreement between MFBIA and the isotope methods were ±14% and ±9% for cirrhotics (extracellular water and total body water, respectively) and ±9% and ±9% for cirrhotics without ascites. The 95% confidence intervals estimated from the control group were ±10% and ±5% for extracellular water and total body water, respectively. Thus, despite strong correlations between MFBIA and isotope measurements, the relatively large limits of agreement with accepted techniques suggest that the MFBIA technique requires further refinement before it can be routinely used to determine the nutritional assessment of individual cirrhotic patients.</p></abstract><textClass><keywords scheme="keyword"><list><head>article-category</head><item><term>Applied nutritional investigation</term></item></list></keywords></textClass><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>multiple-frequency bioelectrical impedance</term></item><item><term>cirrhosis</term></item><item><term>ascites</term></item><item><term>total body water</term></item><item><term>liver</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2001">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/337CBBCDCCF76CEA6956402C42148BB26393E629/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: ce:floats; body; tail"><istex:xmlDeclaration>version="1.0" encoding="utf-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="fla" xml:lang="en"><item-info><jid>NUT</jid><aid>6267</aid><ce:pii>S0899-9007(00)00473-1</ce:pii><ce:doi>10.1016/S0899-9007(00)00473-1</ce:doi><ce:copyright type="full-transfer" year="2001">Elsevier Science Inc.</ce:copyright><ce:doctopics><ce:doctopic><ce:text>Applied nutritional investigation</ce:text></ce:doctopic></ce:doctopics></item-info><head><ce:article-footnote><ce:label>☆</ce:label><ce:note-para>This study was supported by the Reginald Ferguson Foundation, Greenslopes Hospital, Brisbane, Australia.</ce:note-para></ce:article-footnote><ce:dochead><ce:textfn>Applied nutritional investigation</ce:textfn></ce:dochead><ce:title>Estimation of body water compartments in cirrhosis by multiple-frequency bioelectrical-impedance analysis</ce:title><ce:author-group><ce:author><ce:given-name>Megan E</ce:given-name><ce:surname>Lehnert</ce:surname><ce:degrees>BSc</ce:degrees><ce:cross-ref refid="AFF1"><ce:sup>a</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>David D</ce:given-name><ce:surname>Clarke</ce:surname><ce:degrees>MD</ce:degrees><ce:cross-ref refid="AFF2"><ce:sup>d</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>John G</ce:given-name><ce:surname>Gibbons</ce:surname><ce:roles>FRACP</ce:roles><ce:cross-ref refid="AFF1"><ce:sup>a</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Leigh C</ce:given-name><ce:surname>Ward</ce:surname><ce:degrees>PhD</ce:degrees><ce:cross-ref refid="AFF3"><ce:sup>e</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Sue M</ce:given-name><ce:surname>Golding</ce:surname><ce:degrees>PhD</ce:degrees><ce:cross-ref refid="AFF4"><ce:sup>f</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Ross W</ce:given-name><ce:surname>Shepherd</ce:surname><ce:degrees>MD</ce:degrees><ce:roles>FRACP</ce:roles><ce:cross-ref refid="AFF2"><ce:sup>d</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Bruce H</ce:given-name><ce:surname>Cornish</ce:surname><ce:degrees>PhD</ce:degrees><ce:cross-ref refid="AFF5"><ce:sup>b</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Darrell H.G</ce:given-name><ce:surname>Crawford</ce:surname><ce:degrees>MD</ce:degrees><ce:roles>FRACP</ce:roles><ce:cross-ref refid="AFF1"><ce:sup>a</ce:sup></ce:cross-ref><ce:cross-ref refid="AFF6"><ce:sup>c</ce:sup></ce:cross-ref><ce:cross-ref refid="CORR1">*</ce:cross-ref></ce:author><ce:affiliation id="AFF1"><ce:label>a</ce:label><ce:textfn>Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia</ce:textfn></ce:affiliation><ce:affiliation id="AFF5"><ce:label>b</ce:label><ce:textfn>School of Physics, Queensland University of Technology, Brisbane, Queensland, Australia</ce:textfn></ce:affiliation><ce:affiliation id="AFF6"><ce:label>c</ce:label><ce:textfn>Department of Medicine, University of Queensland, Brisbane, Queensland, Australia</ce:textfn></ce:affiliation><ce:affiliation id="AFF2"><ce:label>d</ce:label><ce:textfn>Department of Child Health, University of Queensland, Brisbane, Queensland, Australia</ce:textfn></ce:affiliation><ce:affiliation id="AFF3"><ce:label>e</ce:label><ce:textfn>Department of Biochemistry, University of Queensland, Brisbane, Queensland, Australia</ce:textfn></ce:affiliation><ce:affiliation id="AFF4"><ce:label>f</ce:label><ce:textfn>Department of Earth Sciences, University of Queensland, Brisbane, Queensland, Australia</ce:textfn></ce:affiliation><ce:correspondence id="CORR1"><ce:label>*</ce:label><ce:text>Correspondence to: Darrell H. G. Crawford, MD, FRACP, Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Queensland 4102, Australia</ce:text></ce:correspondence></ce:author-group><ce:abstract><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para>Estimation of total body water by measuring bioelectrical impedance at a fixed frequency of 50 kHz is useful in assessing body composition in healthy populations. However, in cirrhosis, the distribution of total body water between the extracellular and intracellular compartments is of greater clinical importance. We report an evaluation of a new multiple-frequency bioelectrical-impedance analysis technique (MFBIA) that may quantify the distribution of total body water in cirrhosis. In 21 cirrhotic patients and 21 healthy control subjects, impedance to the flow of current was measured at frequencies ranging from 4 to 1012 kHz. These measurements were used to estimate body water compartments and then compared with total body water and extracellular water determined by isotope methodology. In cirrhotic patients, extracellular water and total body water (as determined by isotope methods) were well predicted by MFBIA (<ce:italic>r</ce:italic> = 0.73 and 0.89, respectively). However, the 95% confidence intervals of the limits of agreement between MFBIA and the isotope methods were ±14% and ±9% for cirrhotics (extracellular water and total body water, respectively) and ±9% and ±9% for cirrhotics without ascites. The 95% confidence intervals estimated from the control group were ±10% and ±5% for extracellular water and total body water, respectively. Thus, despite strong correlations between MFBIA and isotope measurements, the relatively large limits of agreement with accepted techniques suggest that the MFBIA technique requires further refinement before it can be routinely used to determine the nutritional assessment of individual cirrhotic patients.</ce:simple-para></ce:abstract-sec></ce:abstract><ce:keywords class="keyword"><ce:section-title>Keywords</ce:section-title><ce:keyword><ce:text>multiple-frequency bioelectrical impedance</ce:text></ce:keyword><ce:keyword><ce:text>cirrhosis</ce:text></ce:keyword><ce:keyword><ce:text>ascites</ce:text></ce:keyword><ce:keyword><ce:text>total body water</ce:text></ce:keyword><ce:keyword><ce:text>liver</ce:text></ce:keyword></ce:keywords></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Estimation of body water compartments in cirrhosis by multiple-frequency bioelectrical-impedance analysis</title></titleInfo><titleInfo type="alternative" lang="en" contentType="CDATA"><title>Estimation of body water compartments in cirrhosis by multiple-frequency bioelectrical-impedance analysis</title></titleInfo><name type="personal"><namePart type="given">Megan E</namePart><namePart type="family">Lehnert</namePart><namePart type="termsOfAddress">BSc</namePart><affiliation>Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">David D</namePart><namePart type="family">Clarke</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Child Health, University of Queensland, Brisbane, Queensland, Australia</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">John G</namePart><namePart type="family">Gibbons</namePart><description>FRACP</description><affiliation>Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Leigh C</namePart><namePart type="family">Ward</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Biochemistry, University of Queensland, Brisbane, Queensland, Australia</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Sue M</namePart><namePart type="family">Golding</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Earth Sciences, University of Queensland, Brisbane, Queensland, Australia</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ross W</namePart><namePart type="family">Shepherd</namePart><namePart type="termsOfAddress">MD</namePart><description>FRACP</description><affiliation>Department of Child Health, University of Queensland, Brisbane, Queensland, Australia</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Bruce H</namePart><namePart type="family">Cornish</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>School of Physics, Queensland University of Technology, Brisbane, Queensland, Australia</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Darrell H.G</namePart><namePart type="family">Crawford</namePart><namePart type="termsOfAddress">MD</namePart><description>FRACP</description><affiliation>Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia</affiliation><description>Correspondence to: Darrell H. G. Crawford, MD, FRACP, Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Queensland 4102, Australia</description><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article"></genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">2001</dateIssued><copyrightDate encoding="w3cdtf">2001</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">Estimation of total body water by measuring bioelectrical impedance at a fixed frequency of 50 kHz is useful in assessing body composition in healthy populations. However, in cirrhosis, the distribution of total body water between the extracellular and intracellular compartments is of greater clinical importance. We report an evaluation of a new multiple-frequency bioelectrical-impedance analysis technique (MFBIA) that may quantify the distribution of total body water in cirrhosis. In 21 cirrhotic patients and 21 healthy control subjects, impedance to the flow of current was measured at frequencies ranging from 4 to 1012 kHz. These measurements were used to estimate body water compartments and then compared with total body water and extracellular water determined by isotope methodology. In cirrhotic patients, extracellular water and total body water (as determined by isotope methods) were well predicted by MFBIA (r = 0.73 and 0.89, respectively). However, the 95% confidence intervals of the limits of agreement between MFBIA and the isotope methods were ±14% and ±9% for cirrhotics (extracellular water and total body water, respectively) and ±9% and ±9% for cirrhotics without ascites. The 95% confidence intervals estimated from the control group were ±10% and ±5% for extracellular water and total body water, respectively. Thus, despite strong correlations between MFBIA and isotope measurements, the relatively large limits of agreement with accepted techniques suggest that the MFBIA technique requires further refinement before it can be routinely used to determine the nutritional assessment of individual cirrhotic patients.</abstract><note>This study was supported by the Reginald Ferguson Foundation, Greenslopes Hospital, Brisbane, Australia.</note><note type="content">Section title: Applied nutritional investigation</note><note type="content">Table I: Characteristics of study groupslegend</note><note type="content">TABLE II: Regression Analysis of MFBIA versus Body Water (measured by isotope methodology)legend</note><note type="content">TABLE III: Limits of agreement for MFBIA Versus Body Water (measured by isotope methodology)legend</note><subject><genre>article-category</genre><topic>Applied nutritional investigation</topic></subject><subject lang="en"><genre>Keywords</genre><topic>multiple-frequency bioelectrical impedance</topic><topic>cirrhosis</topic><topic>ascites</topic><topic>total body water</topic><topic>liver</topic></subject><relatedItem type="host"><titleInfo><title>Nutrition</title></titleInfo><titleInfo type="abbreviated"><title>NUT</title></titleInfo><genre type="journal">journal</genre><originInfo><dateIssued encoding="w3cdtf">200101</dateIssued></originInfo><identifier type="ISSN">0899-9007</identifier><identifier type="PII">S0899-9007(00)X0048-2</identifier><part><date>200101</date><detail type="volume"><number>17</number><caption>vol.</caption></detail><detail type="issue"><number>1</number><caption>no.</caption></detail><extent unit="issue pages"><start>1</start><end>84</end></extent><extent unit="pages"><start>31</start><end>34</end></extent></part></relatedItem><identifier type="istex">337CBBCDCCF76CEA6956402C42148BB26393E629</identifier><identifier type="DOI">10.1016/S0899-9007(00)00473-1</identifier><identifier type="PII">S0899-9007(00)00473-1</identifier><accessCondition type="use and reproduction" contentType="copyright">©2001 Elsevier Science Inc.</accessCondition><recordInfo><recordContentSource>ELSEVIER</recordContentSource><recordOrigin>Elsevier Science Inc., ©2001</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001772 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 001772 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:337CBBCDCCF76CEA6956402C42148BB26393E629
|texte= Estimation of body water compartments in cirrhosis by multiple-frequency bioelectrical-impedance analysis
}}
| This area was generated with Dilib version V0.6.31. |  |