P‐34 A case of exfoliative erythema multiforme associated with herpes virus 1 infection in a European cat
Identifieur interne : 001364 ( Istex/Corpus ); précédent : 001363; suivant : 001365P‐34 A case of exfoliative erythema multiforme associated with herpes virus 1 infection in a European cat
Auteurs : C. ProstSource :
- Veterinary Dermatology [ 0959-4493 ] ; 2004-08.
Abstract
A 2‐year‐old female domestic short‐haired cat was referred with a 1‐month history of extensive scaling and alopecic dermatitis. Clinical signs appeared suddenly 2 weeks after ocular and upper respiratory tract signs that were treated with amoxicillin and marbofloxacin. Physical examination revealed widespread scaling and alopecic dermatitis. The skin was firm with a cardboard‐like texture. The ocular and nasal mucous membranes were inflamed. The cat was lethargic and reluctant to move. FeLV and FIV tests were negative. Skin scrapings failed to reveal any evidence of ectoparasites and dermatophytes. Thoracic radiographs showed no abnormalities. Skin biopsy specimens were collected from the face and the trunk under general anaesthesia. Histopathologic examination revealed a lymphocytic interface dermatitis with many mast cells, severe hydropic degeneration of basal cells, and numerous apoptotic keratinocytes (with satellitosis) at all levels of the epidermis. The epidermis was hyperplastic with orthokeratotic hyperkeratosis and some foci of parakeratosis. Hair follicles were atrophic and a diffuse fibrosis was noted within the dermis. Ultrasonographic examination of the thorax and abdomen failed to reveal any abnormalities. PCR evaluation of skin specimens, as well as nasal and ocular discharges, confirmed the presence of feline herpes virus type 1. Antiviral treatments were implemented (aciclovir dosed at 50–100 mg/kg twice daily and ocular idoxuridine) with spectacular improvement. Unfortunately, the drugs had to be discontinued due to hepatic toxicity. Omega interferon was also used, but without success. A few months later, spontaneous recovery was observed. Funding: Self‐funded.
Url:
DOI: 10.1111/j.1365-3164.2004.00414_34.x
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ISTEX:2A6FBD2FB868DFF6F488A3325A5E26628EB88C4ALe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">P‐34 A case of exfoliative erythema multiforme associated with herpes virus 1 infection in a European cat</title><author><name sortKey="Prost, C" sort="Prost, C" uniqKey="Prost C" first="C." last="Prost">C. Prost</name><affiliation><mods:affiliation>26 rue Des Tilleuls, Pusignan France</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:2A6FBD2FB868DFF6F488A3325A5E26628EB88C4A</idno><date when="2004" year="2004">2004</date><idno type="doi">10.1111/j.1365-3164.2004.00414_34.x</idno><idno type="url">https://api.istex.fr/document/2A6FBD2FB868DFF6F488A3325A5E26628EB88C4A/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001364</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001364</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">P‐34
A case of exfoliative erythema multiforme associated with herpes virus 1 infection in a European cat</title><author><name sortKey="Prost, C" sort="Prost, C" uniqKey="Prost C" first="C." last="Prost">C. Prost</name><affiliation><mods:affiliation>26 rue Des Tilleuls, Pusignan France</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Veterinary Dermatology</title><title level="j" type="alt">VETERINARY DERMATOLOGY</title><idno type="ISSN">0959-4493</idno><idno type="eISSN">1365-3164</idno><imprint><biblScope unit="vol">15</biblScope><biblScope unit="page" from="51">51</biblScope><biblScope unit="page" to="51">51</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2004-08">2004-08</date></imprint><idno type="ISSN">0959-4493</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0959-4493</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A 2‐year‐old female domestic short‐haired cat was referred with a 1‐month history of extensive scaling and alopecic dermatitis. Clinical signs appeared suddenly 2 weeks after ocular and upper respiratory tract signs that were treated with amoxicillin and marbofloxacin. Physical examination revealed widespread scaling and alopecic dermatitis. The skin was firm with a cardboard‐like texture. The ocular and nasal mucous membranes were inflamed. The cat was lethargic and reluctant to move. FeLV and FIV tests were negative. Skin scrapings failed to reveal any evidence of ectoparasites and dermatophytes. Thoracic radiographs showed no abnormalities. Skin biopsy specimens were collected from the face and the trunk under general anaesthesia. Histopathologic examination revealed a lymphocytic interface dermatitis with many mast cells, severe hydropic degeneration of basal cells, and numerous apoptotic keratinocytes (with satellitosis) at all levels of the epidermis. The epidermis was hyperplastic with orthokeratotic hyperkeratosis and some foci of parakeratosis. Hair follicles were atrophic and a diffuse fibrosis was noted within the dermis. Ultrasonographic examination of the thorax and abdomen failed to reveal any abnormalities. PCR evaluation of skin specimens, as well as nasal and ocular discharges, confirmed the presence of feline herpes virus type 1. Antiviral treatments were implemented (aciclovir dosed at 50–100 mg/kg twice daily and ocular idoxuridine) with spectacular improvement. Unfortunately, the drugs had to be discontinued due to hepatic toxicity. Omega interferon was also used, but without success. A few months later, spontaneous recovery was observed. 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Prost</name><affiliations><json:string>26 rue Des Tilleuls, Pusignan France</json:string></affiliations></json:item></author><articleId><json:string>VDE414_34_34</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>abstract</json:string></originalGenre><abstract>A 2‐year‐old female domestic short‐haired cat was referred with a 1‐month history of extensive scaling and alopecic dermatitis. Clinical signs appeared suddenly 2 weeks after ocular and upper respiratory tract signs that were treated with amoxicillin and marbofloxacin. Physical examination revealed widespread scaling and alopecic dermatitis. The skin was firm with a cardboard‐like texture. The ocular and nasal mucous membranes were inflamed. The cat was lethargic and reluctant to move. FeLV and FIV tests were negative. Skin scrapings failed to reveal any evidence of ectoparasites and dermatophytes. Thoracic radiographs showed no abnormalities. Skin biopsy specimens were collected from the face and the trunk under general anaesthesia. Histopathologic examination revealed a lymphocytic interface dermatitis with many mast cells, severe hydropic degeneration of basal cells, and numerous apoptotic keratinocytes (with satellitosis) at all levels of the epidermis. The epidermis was hyperplastic with orthokeratotic hyperkeratosis and some foci of parakeratosis. Hair follicles were atrophic and a diffuse fibrosis was noted within the dermis. Ultrasonographic examination of the thorax and abdomen failed to reveal any abnormalities. PCR evaluation of skin specimens, as well as nasal and ocular discharges, confirmed the presence of feline herpes virus type 1. Antiviral treatments were implemented (aciclovir dosed at 50–100 mg/kg twice daily and ocular idoxuridine) with spectacular improvement. Unfortunately, the drugs had to be discontinued due to hepatic toxicity. Omega interferon was also used, but without success. A few months later, spontaneous recovery was observed. Funding: Self‐funded.</abstract><qualityIndicators><score>8.344</score><pdfVersion>1.4</pdfVersion><pdfPageSize>595 x 842 pts (A4)</pdfPageSize><refBibsNative>false</refBibsNative><abstractCharCount>1709</abstractCharCount><pdfWordCount>20170</pdfWordCount><pdfCharCount>133096</pdfCharCount><pdfPageCount>29</pdfPageCount><abstractWordCount>237</abstractWordCount></qualityIndicators><title>P‐34 A case of exfoliative erythema multiforme associated with herpes virus 1 infection in a European cat</title><genre><json:string>abstract</json:string></genre><host><title>Veterinary Dermatology</title><language><json:string>unknown</json:string></language><doi><json:string>10.1111/(ISSN)1365-3164</json:string></doi><issn><json:string>0959-4493</json:string></issn><eissn><json:string>1365-3164</json:string></eissn><publisherId><json:string>VDE</json:string></publisherId><volume>15</volume><pages><first>51</first><last>51</last></pages><genre><json:string>journal</json:string></genre></host><categories><wos><json:string>science</json:string><json:string>veterinary sciences</json:string><json:string>dermatology</json:string></wos><scienceMetrix><json:string>applied sciences</json:string><json:string>agriculture, fisheries & forestry</json:string><json:string>veterinary sciences</json:string></scienceMetrix><inist><json:string>sciences appliquees, technologies et medecines</json:string><json:string>sciences biologiques et medicales</json:string><json:string>sciences medicales</json:string><json:string>dermatologie</json:string></inist></categories><publicationDate>2004</publicationDate><copyrightDate>2004</copyrightDate><doi><json:string>10.1111/j.1365-3164.2004.00414_34.x</json:string></doi><id>2A6FBD2FB868DFF6F488A3325A5E26628EB88C4A</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/2A6FBD2FB868DFF6F488A3325A5E26628EB88C4A/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/2A6FBD2FB868DFF6F488A3325A5E26628EB88C4A/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/2A6FBD2FB868DFF6F488A3325A5E26628EB88C4A/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main">P‐34
A case of exfoliative erythema multiforme associated with herpes virus 1 infection in a European cat</title></titleStmt><publicationStmt><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2004-08"></date></publicationStmt><notesStmt><note type="content-type" subtype="abstract" source="abstract" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-HPN7T1Q2-R">abstract</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="abstract"><analytic><title level="a" type="main">P‐34
A case of exfoliative erythema multiforme associated with herpes virus 1 infection in a European cat</title><title level="a" type="short">Poster Abstracts</title><author xml:id="author-0000"><persName><forename type="first">C.</forename><surname>Prost</surname></persName><affiliation>26 rue Des Tilleuls, Pusignan France<address><country key="FR"></country></address></affiliation></author><idno type="istex">2A6FBD2FB868DFF6F488A3325A5E26628EB88C4A</idno><idno type="DOI">10.1111/j.1365-3164.2004.00414_34.x</idno><idno type="unit">VDE414_34_34</idno><idno type="toTypesetVersion">file:VDE.VDE414_34_34.pdf</idno></analytic><monogr><title level="j" type="main">Veterinary Dermatology</title><title level="j" type="alt">VETERINARY DERMATOLOGY</title><idno type="pISSN">0959-4493</idno><idno type="eISSN">1365-3164</idno><idno type="book-DOI">10.1111/(ISSN)1365-3164</idno><idno type="book-part-DOI">10.1111/vde.2004.15.issue-s1</idno><idno type="product">VDE</idno><idno type="publisherDivision">ST</idno><imprint><biblScope unit="vol">15</biblScope><biblScope unit="page" from="51">51</biblScope><biblScope unit="page" to="51">51</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2004-08"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main"><p>A 2‐year‐old female domestic short‐haired cat was referred with a 1‐month history of extensive scaling and alopecic dermatitis. Clinical signs appeared suddenly 2 weeks after ocular and upper respiratory tract signs that were treated with amoxicillin and marbofloxacin. Physical examination revealed widespread scaling and alopecic dermatitis. The skin was firm with a cardboard‐like texture. The ocular and nasal mucous membranes were inflamed. The cat was lethargic and reluctant to move. FeLV and FIV tests were negative. Skin scrapings failed to reveal any evidence of ectoparasites and dermatophytes. Thoracic radiographs showed no abnormalities. Skin biopsy specimens were collected from the face and the trunk under general anaesthesia. Histopathologic examination revealed a lymphocytic interface dermatitis with many mast cells, severe hydropic degeneration of basal cells, and numerous apoptotic keratinocytes (with satellitosis) at all levels of the epidermis. The epidermis was hyperplastic with orthokeratotic hyperkeratosis and some foci of parakeratosis. Hair follicles were atrophic and a diffuse fibrosis was noted within the dermis. Ultrasonographic examination of the thorax and abdomen failed to reveal any abnormalities. PCR evaluation of skin specimens, as well as nasal and ocular discharges, confirmed the presence of feline herpes virus type 1. Antiviral treatments were implemented (aciclovir dosed at 50–100 mg/kg twice daily and ocular idoxuridine) with spectacular improvement. Unfortunately, the drugs had to be discontinued due to hepatic toxicity. Omega interferon was also used, but without success. A few months later, spontaneous recovery was observed.</p><p>
<hi rend="italic">Funding: Self‐funded.</hi>
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A case of exfoliative erythema multiforme associated with herpes virus 1 infection in a European cat</title><title type="short">Poster Abstracts</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#aff-1-1"><personName><givenNames>C.</givenNames><familyName>Prost</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="aff-1-1" countryCode="FR"><unparsedAffiliation>26 rue Des Tilleuls, Pusignan France</unparsedAffiliation></affiliation></affiliationGroup><abstractGroup><abstract type="main" xml:lang="en"><p>A 2‐year‐old female domestic short‐haired cat was referred with a 1‐month history of extensive scaling and alopecic dermatitis. Clinical signs appeared suddenly 2 weeks after ocular and upper respiratory tract signs that were treated with amoxicillin and marbofloxacin. Physical examination revealed widespread scaling and alopecic dermatitis. The skin was firm with a cardboard‐like texture. The ocular and nasal mucous membranes were inflamed. The cat was lethargic and reluctant to move. FeLV and FIV tests were negative. Skin scrapings failed to reveal any evidence of ectoparasites and dermatophytes. Thoracic radiographs showed no abnormalities. Skin biopsy specimens were collected from the face and the trunk under general anaesthesia. Histopathologic examination revealed a lymphocytic interface dermatitis with many mast cells, severe hydropic degeneration of basal cells, and numerous apoptotic keratinocytes (with satellitosis) at all levels of the epidermis. The epidermis was hyperplastic with orthokeratotic hyperkeratosis and some foci of parakeratosis. Hair follicles were atrophic and a diffuse fibrosis was noted within the dermis. Ultrasonographic examination of the thorax and abdomen failed to reveal any abnormalities. PCR evaluation of skin specimens, as well as nasal and ocular discharges, confirmed the presence of feline herpes virus type 1. Antiviral treatments were implemented (aciclovir dosed at 50–100 mg/kg twice daily and ocular idoxuridine) with spectacular improvement. Unfortunately, the drugs had to be discontinued due to hepatic toxicity. Omega interferon was also used, but without success. A few months later, spontaneous recovery was observed.</p><p> <i>Funding: Self‐funded.</i> </p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>P‐34 A case of exfoliative erythema multiforme associated with herpes virus 1 infection in a European cat</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Poster Abstracts</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>P‐34
A case of exfoliative erythema multiforme associated with herpes virus 1 infection in a European cat</title></titleInfo><name type="personal"><namePart type="given">C.</namePart><namePart type="family">Prost</namePart><affiliation>26 rue Des Tilleuls, Pusignan France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="abstract" displayLabel="abstract"></genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2004-08</dateIssued><copyrightDate encoding="w3cdtf">2004</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">A 2‐year‐old female domestic short‐haired cat was referred with a 1‐month history of extensive scaling and alopecic dermatitis. Clinical signs appeared suddenly 2 weeks after ocular and upper respiratory tract signs that were treated with amoxicillin and marbofloxacin. Physical examination revealed widespread scaling and alopecic dermatitis. The skin was firm with a cardboard‐like texture. The ocular and nasal mucous membranes were inflamed. The cat was lethargic and reluctant to move. FeLV and FIV tests were negative. Skin scrapings failed to reveal any evidence of ectoparasites and dermatophytes. Thoracic radiographs showed no abnormalities. Skin biopsy specimens were collected from the face and the trunk under general anaesthesia. Histopathologic examination revealed a lymphocytic interface dermatitis with many mast cells, severe hydropic degeneration of basal cells, and numerous apoptotic keratinocytes (with satellitosis) at all levels of the epidermis. The epidermis was hyperplastic with orthokeratotic hyperkeratosis and some foci of parakeratosis. Hair follicles were atrophic and a diffuse fibrosis was noted within the dermis. Ultrasonographic examination of the thorax and abdomen failed to reveal any abnormalities. PCR evaluation of skin specimens, as well as nasal and ocular discharges, confirmed the presence of feline herpes virus type 1. Antiviral treatments were implemented (aciclovir dosed at 50–100 mg/kg twice daily and ocular idoxuridine) with spectacular improvement. Unfortunately, the drugs had to be discontinued due to hepatic toxicity. Omega interferon was also used, but without success. A few months later, spontaneous recovery was observed. Funding: Self‐funded.</abstract><relatedItem type="host"><titleInfo><title>Veterinary Dermatology</title></titleInfo><genre type="journal">journal</genre><identifier type="ISSN">0959-4493</identifier><identifier type="eISSN">1365-3164</identifier><identifier type="DOI">10.1111/(ISSN)1365-3164</identifier><identifier type="PublisherID">VDE</identifier><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>15</number></detail><detail type="supplement"><caption>Suppl. no.</caption><number>s1</number></detail><extent unit="pages"><start>51</start><end>51</end></extent></part></relatedItem><identifier type="istex">2A6FBD2FB868DFF6F488A3325A5E26628EB88C4A</identifier><identifier type="DOI">10.1111/j.1365-3164.2004.00414_34.x</identifier><identifier type="ArticleID">VDE414_34_34</identifier><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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