Mutation identification of Fabry disease in families with other lysosomal storage disorders
Identifieur interne : 001003 ( Istex/Corpus ); précédent : 001002; suivant : 001004Mutation identification of Fabry disease in families with other lysosomal storage disorders
Auteurs : A. Zampetti ; L. Fania ; D. Antuzzi ; F. Giurdanella ; M. Gnarra ; F. Bertola ; S. Lualdi ; M. Filocamo ; A. Morrone ; C. FelicianiSource :
- Clinical Genetics [ 0009-9163 ] ; 2013-09.
Abstract
Fabry disease (FD) is an X‐linked lysosomal storage disorder (LSD) caused by the deficiency of the enzyme α‐galactosidase. It exhibits a wide clinical spectrum that may lead to a delayed or even missed diagnosis and the real incidence can be underestimated. We report the cases of two unrelated Italian families in whom FD was incidentally diagnosed in two females. In both families, the risk for other lysosomal disorders was known from other members affected by fucosidosis or mucopolysaccharidosis I Hurler/Scheie. Some subjects were simultaneously heterozygous for Fabry and the other lysosomal deficiency. Our study shows that the risk for more than one LSDs can occur in a family pedigree. The diagnosis of Fabry in female probands represents a diagnostic challenge, as symptoms and signs can be variably present because of the random X‐chromosome inactivation.
Url:
DOI: 10.1111/cge.12071
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ISTEX:228E45019F19780E29673068F8E525F7106B8C5ELe document en format XML
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Zampetti</name><affiliation><mods:affiliation>Department of Dermatology</mods:affiliation></affiliation><affiliation><mods:affiliation>Corresponding author: Anna Zampetti, MD, PhD, Department of Dermatology, Policlinico A. Gemelli, Università Cattolica del Sacro Cuore, Largo Gemelli 8, 00168 Rome, Italy.Tel.: +39 06 30154227;fax: +39 06 3016293;e‐mail:</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: anna.zampetti@gmail.com</mods:affiliation></affiliation></author><author><name sortKey="Fania, L" sort="Fania, L" uniqKey="Fania L" first="L" last="Fania">L. Fania</name><affiliation><mods:affiliation>Department of Dermatology</mods:affiliation></affiliation></author><author><name sortKey="Antuzzi, D" sort="Antuzzi, D" uniqKey="Antuzzi D" first="D" last="Antuzzi">D. Antuzzi</name><affiliation><mods:affiliation>Department of Pediatric Sciences, Policlinico “A. Gemelli”, Università Cattolica del Sacro Cuore, Rome, Italy</mods:affiliation></affiliation></author><author><name sortKey="Giurdanella, F" sort="Giurdanella, F" uniqKey="Giurdanella F" first="F" last="Giurdanella">F. Giurdanella</name><affiliation><mods:affiliation>Department of Dermatology</mods:affiliation></affiliation></author><author><name sortKey="Gnarra, M" sort="Gnarra, M" uniqKey="Gnarra M" first="M" last="Gnarra">M. Gnarra</name><affiliation><mods:affiliation>Department of Dermatology</mods:affiliation></affiliation></author><author><name sortKey="Bertola, F" sort="Bertola, F" uniqKey="Bertola F" first="F" last="Bertola">F. Bertola</name><affiliation><mods:affiliation>Consortium for Human Molecular Genetics, University of Milano‐Bicocca, Monza, Italy</mods:affiliation></affiliation></author><author><name sortKey="Lualdi, S" sort="Lualdi, S" uniqKey="Lualdi S" first="S" last="Lualdi">S. 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Morrone</name><affiliation><mods:affiliation>Laboratory for Molecular and Cell Biology of Neurologic and Metabolic Disorders, Paediatric Neurology Unit, Meyer Children's Hospital, Florence, Italy</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Sciences for Woman and Child's Health, University of Florence, Florence, Italy</mods:affiliation></affiliation></author><author><name sortKey="Feliciani, C" sort="Feliciani, C" uniqKey="Feliciani C" first="C" last="Feliciani">C. Feliciani</name><affiliation><mods:affiliation>Department of Dermatology</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Clinical Genetics</title><title level="j" type="alt">CLINICAL GENETICS</title><idno type="ISSN">0009-9163</idno><idno type="eISSN">1399-0004</idno><imprint><biblScope unit="vol">84</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="281">281</biblScope><biblScope unit="page" to="285">285</biblScope><biblScope unit="page-count">5</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2013-09">2013-09</date></imprint><idno type="ISSN">0009-9163</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0009-9163</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">Fabry disease (FD) is an X‐linked lysosomal storage disorder (LSD) caused by the deficiency of the enzyme α‐galactosidase. It exhibits a wide clinical spectrum that may lead to a delayed or even missed diagnosis and the real incidence can be underestimated. We report the cases of two unrelated Italian families in whom FD was incidentally diagnosed in two females. In both families, the risk for other lysosomal disorders was known from other members affected by fucosidosis or mucopolysaccharidosis I Hurler/Scheie. Some subjects were simultaneously heterozygous for Fabry and the other lysosomal deficiency. Our study shows that the risk for more than one LSDs can occur in a family pedigree. 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Gemelli”, Università Cattolica del Sacro Cuore, Rome, Italy</json:string></affiliations></json:item><json:item><name>F Giurdanella</name><affiliations><json:string>Department of Dermatology</json:string></affiliations></json:item><json:item><name>M Gnarra</name><affiliations><json:string>Department of Dermatology</json:string></affiliations></json:item><json:item><name>F Bertola</name><affiliations><json:string>Consortium for Human Molecular Genetics, University of Milano‐Bicocca, Monza, Italy</json:string></affiliations></json:item><json:item><name>S Lualdi</name><affiliations><json:string>Centro di Diagnostica Genetica e Biochimica delle Malattie Metaboliche, Istituto G. Gaslini, Genova, Italy</json:string></affiliations></json:item><json:item><name>M Filocamo</name><affiliations><json:string>Centro di Diagnostica Genetica e Biochimica delle Malattie Metaboliche, Istituto G. Gaslini, Genova, Italy</json:string></affiliations></json:item><json:item><name>A Morrone</name><affiliations><json:string>Laboratory for Molecular and Cell Biology of Neurologic and Metabolic Disorders, Paediatric Neurology Unit, Meyer Children's Hospital, Florence, Italy</json:string><json:string>Department of Sciences for Woman and Child's Health, University of Florence, Florence, Italy</json:string></affiliations></json:item><json:item><name>C Feliciani</name><affiliations><json:string>Department of Dermatology</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Fabry</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>fucosidosis</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>GLA mutation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>mucopolysaccharidosis</value></json:item></subject><articleId><json:string>CGE12071</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>shortCommunication</json:string></originalGenre><abstract>Fabry disease (FD) is an X‐linked lysosomal storage disorder (LSD) caused by the deficiency of the enzyme α‐galactosidase. 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Gemelli, Università Cattolica del Sacro Cuore, Largo Gemelli 8, 00168 Rome, Italy. Tel.: +39 06 30154227; fax: +39 06 3016293; e‐mail: anna.zampetti@gmail.com</affiliation></author><author xml:id="author-0001"><persName><forename type="first">L</forename><surname>Fania</surname></persName><affiliation>Department of Dermatology</affiliation></author><author xml:id="author-0002"><persName><forename type="first">D</forename><surname>Antuzzi</surname></persName><affiliation><orgName>Department of Pediatric Sciences</orgName><orgName>Policlinico “A. 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It exhibits a wide clinical spectrum that may lead to a delayed or even missed diagnosis and the real incidence can be underestimated. We report the cases of two unrelated Italian families in whom FD was incidentally diagnosed in two females. In both families, the risk for other lysosomal disorders was known from other members affected by fucosidosis or mucopolysaccharidosis I Hurler/Scheie. Some subjects were simultaneously heterozygous for Fabry and the other lysosomal deficiency. Our study shows that the risk for more than one LSDs can occur in a family pedigree. The diagnosis of Fabry in female probands represents a diagnostic challenge, as symptoms and signs can be variably present because of the random X‐chromosome inactivation.</p></abstract><textClass><keywords><term xml:id="cge12071-kwd-0001">Fabry</term><term xml:id="cge12071-kwd-0002">fucosidosis</term><term xml:id="cge12071-kwd-0003"><hi rend="fc">GLA</hi> mutation</term><term xml:id="cge12071-kwd-0004">mucopolysaccharidosis</term></keywords><classCode scheme="articleCategory">SHORT REPORT</classCode><classCode scheme="tocHeading1">SHORT REPORTS</classCode></textClass><langUsage><language ident="EN"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/228E45019F19780E29673068F8E525F7106B8C5E/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en" xml:id="cge12071"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi>10.1111/(ISSN)1399-0004</doi><issn type="print">0009-9163</issn><issn type="electronic">1399-0004</issn><idGroup><id type="product" value="CGE"></id></idGroup><titleGroup><title type="main" sort="CLINICAL GENETICS">Clinical Genetics</title><title type="short">Clin Genet</title></titleGroup></publicationMeta><publicationMeta level="part" position="30"><doi origin="wiley">10.1111/cge.2013.84.issue-3</doi><copyright ownership="publisher">© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd</copyright><numberingGroup><numbering type="journalVolume" number="84">84</numbering><numbering type="journalIssue">3</numbering></numberingGroup><coverDate startDate="2013-09">September 2013</coverDate></publicationMeta><publicationMeta level="unit" position="160" type="shortCommunication" status="forIssue"><doi>10.1111/cge.12071</doi><idGroup><id type="unit" value="CGE12071"></id></idGroup><countGroup><count type="pageTotal" number="5"></count></countGroup><titleGroup><title type="articleCategory">SHORT REPORT</title><title type="tocHeading1">SHORT REPORTS</title></titleGroup><copyright ownership="publisher">© 2012 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd</copyright><eventGroup><event type="manuscriptReceived" date="2012-07-04"></event><event type="manuscriptRevised" date="2012-11-29"></event><event type="manuscriptAccepted" date="2012-11-29"></event><event type="xmlCreated" agent="Laserwords Private Ltd." date="2012-12-10"></event><event type="publishedOnlineAccepted" date="2012-12-04"></event><event type="publishedOnlineEarlyUnpaginated" date="2012-12-28"></event><event type="firstOnline" date="2012-12-28"></event><event type="publishedOnlineFinalForm" date="2013-08-12"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-09"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.6.4 mode:FullText" date="2015-10-03"></event></eventGroup><numberingGroup><numbering type="pageFirst">281</numbering><numbering type="pageLast">285</numbering></numberingGroup><correspondenceTo><lineatedText><line>Corresponding author: Anna Zampetti, MD, PhD, Department of Dermatology, Policlinico A. Gemelli, Università Cattolica del Sacro Cuore, Largo Gemelli 8, 00168 Rome, Italy.</line><line>Tel.: +39 06 30154227;</line><line>fax: +39 06 3016293;</line><line>e‐mail: <email>anna.zampetti@gmail.com</email></line></lineatedText></correspondenceTo><selfCitationGroup><citation type="self" xml:id="cge12071-cit-0000"><author><familyName>Zampetti</familyName>
<givenNames>A</givenNames></author>, <author><familyName>Fania</familyName>
<givenNames>L</givenNames></author>, <author><familyName>Antuzzi</familyName>
<givenNames>D</givenNames></author>, <author><familyName>Giurdanella</familyName>
<givenNames>F</givenNames></author>, <author><familyName>Gnarra</familyName>
<givenNames>M</givenNames></author>, <author><familyName>Bertola</familyName>
<givenNames>F</givenNames></author>, <author><familyName>Lualdi</familyName>
<givenNames>S</givenNames></author>, <author><familyName>Filocamo</familyName>
<givenNames>M</givenNames></author>, <author><familyName>Morrone</familyName>
<givenNames>A</givenNames></author>, <author><familyName>Feliciani</familyName>
<givenNames>C</givenNames></author>. <articleTitle>Mutation identification of Fabry disease in families with other lysosomal storage disorders</articleTitle>.</citation></selfCitationGroup><linkGroup><link type="toTypesetVersion" href="file:CGE.CGE12071.pdf"></link></linkGroup></publicationMeta><contentMeta><titleGroup><title type="main">Mutation identification of Fabry disease in families with other lysosomal storage disorders</title><title type="short">Fabry disease and other LSDs</title><title type="shortAuthors">Zampetti et al.</title></titleGroup><creators><creator creatorRole="author" xml:id="cge12071-cr-0001" affiliationRef="#cge12071-aff-0001" corresponding="yes"><personName><givenNames>A</givenNames>
<familyName>Zampetti</familyName></personName></creator><creator creatorRole="author" xml:id="cge12071-cr-0002" affiliationRef="#cge12071-aff-0001"><personName><givenNames>L</givenNames>
<familyName>Fania</familyName></personName></creator><creator creatorRole="author" xml:id="cge12071-cr-0003" affiliationRef="#cge12071-aff-0002"><personName><givenNames>D</givenNames>
<familyName>Antuzzi</familyName></personName></creator><creator creatorRole="author" xml:id="cge12071-cr-0004" affiliationRef="#cge12071-aff-0001"><personName><givenNames>F</givenNames>
<familyName>Giurdanella</familyName></personName></creator><creator creatorRole="author" xml:id="cge12071-cr-0005" affiliationRef="#cge12071-aff-0001"><personName><givenNames>M</givenNames>
<familyName>Gnarra</familyName></personName></creator><creator creatorRole="author" xml:id="cge12071-cr-0006" affiliationRef="#cge12071-aff-0003"><personName><givenNames>F</givenNames>
<familyName>Bertola</familyName></personName></creator><creator creatorRole="author" xml:id="cge12071-cr-0007" affiliationRef="#cge12071-aff-0004"><personName><givenNames>S</givenNames>
<familyName>Lualdi</familyName></personName></creator><creator creatorRole="author" xml:id="cge12071-cr-0008" affiliationRef="#cge12071-aff-0004"><personName><givenNames>M</givenNames>
<familyName>Filocamo</familyName></personName></creator><creator creatorRole="author" xml:id="cge12071-cr-0009" affiliationRef="#cge12071-aff-0005 #cge12071-aff-0006"><personName><givenNames>A</givenNames>
<familyName>Morrone</familyName></personName></creator><creator creatorRole="author" xml:id="cge12071-cr-0010" affiliationRef="#cge12071-aff-0001"><personName><givenNames>C</givenNames>
<familyName>Feliciani</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="cge12071-aff-0001"><unparsedAffiliation>Department of Dermatology</unparsedAffiliation></affiliation><affiliation countryCode="IT" type="organization" xml:id="cge12071-aff-0002"><orgDiv>Department of Pediatric Sciences</orgDiv><orgName>Policlinico “A. Gemelli”, Università Cattolica del Sacro Cuore</orgName><address><city>Rome</city><country>Italy</country></address></affiliation><affiliation countryCode="IT" type="organization" xml:id="cge12071-aff-0003"><orgDiv>Consortium for Human Molecular Genetics</orgDiv><orgName>University of Milano‐Bicocca</orgName><address><city>Monza</city><country>Italy</country></address></affiliation><affiliation countryCode="IT" type="organization" xml:id="cge12071-aff-0004"><orgDiv>Centro di Diagnostica Genetica e Biochimica delle Malattie Metaboliche</orgDiv><orgName>Istituto G. Gaslini</orgName><address><city>Genova</city><country>Italy</country></address></affiliation><affiliation countryCode="IT" type="organization" xml:id="cge12071-aff-0005"><orgDiv>Laboratory for Molecular and Cell Biology of Neurologic and Metabolic Disorders, Paediatric Neurology Unit</orgDiv><orgName>Meyer Children's Hospital</orgName><address><city>Florence</city><country>Italy</country></address></affiliation><affiliation countryCode="IT" type="organization" xml:id="cge12071-aff-0006"><orgDiv>Department of Sciences for Woman and Child's Health</orgDiv><orgName>University of Florence</orgName><address><city>Florence</city><country>Italy</country></address></affiliation></affiliationGroup><keywordGroup type="author"><keyword xml:id="cge12071-kwd-0001">Fabry</keyword><keyword xml:id="cge12071-kwd-0002">fucosidosis</keyword><keyword xml:id="cge12071-kwd-0003"><fc>GLA</fc> mutation</keyword><keyword xml:id="cge12071-kwd-0004">mucopolysaccharidosis</keyword></keywordGroup><abstractGroup><abstract type="main"><p>Fabry disease (<fc>FD</fc>) is an X‐linked lysosomal storage disorder (LSD) caused by the deficiency of the enzyme α‐galactosidase. It exhibits a wide clinical spectrum that may lead to a delayed or even missed diagnosis and the real incidence can be underestimated. We report the cases of two unrelated Italian families in whom FD was incidentally diagnosed in two females. In both families, the risk for other lysosomal disorders was known from other members affected by fucosidosis or mucopolysaccharidosis I Hurler/Scheie. Some subjects were simultaneously heterozygous for Fabry and the other lysosomal deficiency. Our study shows that the risk for more than one LSDs can occur in a family pedigree. The diagnosis of Fabry in female probands represents a diagnostic challenge, as symptoms and signs can be variably present because of the random X‐chromosome inactivation.</p></abstract></abstractGroup></contentMeta><noteGroup><title type="main">Conflict of interest</title><note xml:id="cge12071-note-0001" numbered="no"><p>The authors declare that they have no conflict of interest.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Mutation identification of Fabry disease in families with other lysosomal storage disorders</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Fabry disease and other LSDs</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Mutation identification of Fabry disease in families with other lysosomal storage disorders</title></titleInfo><name type="personal"><namePart type="given">A</namePart><namePart type="family">Zampetti</namePart><affiliation>Department of Dermatology</affiliation><affiliation>Corresponding author: Anna Zampetti, MD, PhD, Department of Dermatology, Policlinico A. Gemelli, Università Cattolica del Sacro Cuore, Largo Gemelli 8, 00168 Rome, Italy.Tel.: +39 06 30154227;fax: +39 06 3016293;e‐mail:</affiliation><affiliation>E-mail: anna.zampetti@gmail.com</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Fania</namePart><affiliation>Department of Dermatology</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Antuzzi</namePart><affiliation>Department of Pediatric Sciences, Policlinico “A. Gemelli”, Università Cattolica del Sacro Cuore, Rome, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Giurdanella</namePart><affiliation>Department of Dermatology</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Gnarra</namePart><affiliation>Department of Dermatology</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Bertola</namePart><affiliation>Consortium for Human Molecular Genetics, University of Milano‐Bicocca, Monza, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Lualdi</namePart><affiliation>Centro di Diagnostica Genetica e Biochimica delle Malattie Metaboliche, Istituto G. Gaslini, Genova, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Filocamo</namePart><affiliation>Centro di Diagnostica Genetica e Biochimica delle Malattie Metaboliche, Istituto G. Gaslini, Genova, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Morrone</namePart><affiliation>Laboratory for Molecular and Cell Biology of Neurologic and Metabolic Disorders, Paediatric Neurology Unit, Meyer Children's Hospital, Florence, Italy</affiliation><affiliation>Department of Sciences for Woman and Child's Health, University of Florence, Florence, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Feliciani</namePart><affiliation>Department of Dermatology</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="brief-communication" displayLabel="shortCommunication"></genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2013-09</dateIssued><dateCreated encoding="w3cdtf">2012-12-10</dateCreated><dateCaptured encoding="w3cdtf">2012-07-04</dateCaptured><dateValid encoding="w3cdtf">2012-11-29</dateValid><edition>Zampetti A, Fania L, Antuzzi D, Giurdanella F, Gnarra M, Bertola F, Lualdi S, Filocamo M, Morrone A, Feliciani C. Mutation identification of Fabry disease in families with other lysosomal storage disorders.</edition><copyrightDate encoding="w3cdtf">2013</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract>Fabry disease (FD) is an X‐linked lysosomal storage disorder (LSD) caused by the deficiency of the enzyme α‐galactosidase. It exhibits a wide clinical spectrum that may lead to a delayed or even missed diagnosis and the real incidence can be underestimated. We report the cases of two unrelated Italian families in whom FD was incidentally diagnosed in two females. In both families, the risk for other lysosomal disorders was known from other members affected by fucosidosis or mucopolysaccharidosis I Hurler/Scheie. Some subjects were simultaneously heterozygous for Fabry and the other lysosomal deficiency. Our study shows that the risk for more than one LSDs can occur in a family pedigree. The diagnosis of Fabry in female probands represents a diagnostic challenge, as symptoms and signs can be variably present because of the random X‐chromosome inactivation.</abstract><subject><genre>keywords</genre><topic>Fabry</topic><topic>fucosidosis</topic><topic>GLA mutation</topic><topic>mucopolysaccharidosis</topic></subject><relatedItem type="host"><titleInfo><title>Clinical Genetics</title></titleInfo><titleInfo type="abbreviated"><title>Clin Genet</title></titleInfo><genre type="journal">journal</genre><subject><genre>article-category</genre><topic>SHORT REPORT</topic></subject><identifier type="ISSN">0009-9163</identifier><identifier type="eISSN">1399-0004</identifier><identifier type="DOI">10.1111/(ISSN)1399-0004</identifier><identifier type="PublisherID">CGE</identifier><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>84</number></detail><detail type="issue"><caption>no.</caption><number>3</number></detail><extent unit="pages"><start>281</start><end>285</end><total>5</total></extent></part></relatedItem><identifier type="istex">228E45019F19780E29673068F8E525F7106B8C5E</identifier><identifier type="DOI">10.1111/cge.12071</identifier><identifier type="ArticleID">CGE12071</identifier><accessCondition type="use and reproduction" contentType="copyright">© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd© 2012 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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