Topical antibiotics in chronic sickle cell leg ulcers
Identifieur interne : 005A61 ( Istex/Checkpoint ); précédent : 005A60; suivant : 005A62Topical antibiotics in chronic sickle cell leg ulcers
Auteurs : K. F. Baum [Jamaïque] ; D. E. Macfarlane [Jamaïque] ; G. H. Maude [Jamaïque] ; G. R. Serjeant [Jamaïque]Source :
- Transactions of the Royal Society of Tropical Medicine and Hygiene [ 0035-9203 ] ; 1987.
Abstract
A randomized, controlled, trial of a topical antibiotic preparation (neomycin, bacitracin, and polymyxin B) was performed in 30 patients with homozygous sickle cell (SS) disease and chronic leg ulceration. Over a period of 8 weeks, the reduction in ulcer size was significantly (P < 0·05) greater in the treatment group than in the control group. The results suggest that these topical antibiotics may contribute to the therapy of chronic leg ulceration associated with sickle cell disease.
Url:
DOI: 10.1016/0035-9203(87)90049-6
Affiliations:
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<front><div type="abstract" xml:lang="en">A randomized, controlled, trial of a topical antibiotic preparation (neomycin, bacitracin, and polymyxin B) was performed in 30 patients with homozygous sickle cell (SS) disease and chronic leg ulceration. Over a period of 8 weeks, the reduction in ulcer size was significantly (P < 0·05) greater in the treatment group than in the control group. The results suggest that these topical antibiotics may contribute to the therapy of chronic leg ulceration associated with sickle cell disease.</div>
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