P‐7 Treatment of canine acne with doxycycline: an open trial
Identifieur interne : 001E81 ( Istex/Checkpoint ); précédent : 001E80; suivant : 001E82P‐7 Treatment of canine acne with doxycycline: an open trial
Auteurs : E. Bensignor [France] ; E. Guaguere [France]Source :
- Veterinary Dermatology [ 0959-4493 ] ; 2004-08.
Abstract
The purpose of this study was to determine whether doxycycline (Ronaxan) decreased the severity of localized lesions of canine acne. Dogs were enrolled if they exhibited skin lesions localized to the chin compatible with canine acne, and if cytological smears showed a bacterial invasion and bacteriological samples grew Staphylococcus intermedius colonies. Demodicosis and dermatophytosis were excluded by skin scrapings and fungal culture, respectively. Lesions (erythema, lichenification, papules, pustules and excoriations) were graded with a quantitative 4‐point scale (maximal total score 15). Extent of lesion was also estimated. Pruritus was graded on a 4‐point scale. Scores were given at the time of inclusion and at day 30 after treatment with doxycycline 10 mg/kg once daily. Twelve dogs (10 males and two females) representing seven breeds were included. Good improvement of both lesional (9.4 before treatment and 2.3 after treatment) and extent scores (43% before treatment and 8% after treatment) was achieved. Pruritus was also markedly improved from 2.08 before treatment to 0.42 after treatment. One dog was not significantly improved after 1 month. Results of this trial suggest that doxycyline is useful for reducing the severity of localized skin lesions of canine acne. Funding: Self‐funded.
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DOI: 10.1111/j.1365-3164.2004.00414_7.x
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Treatment of canine acne with doxycycline: an open trial</title><author><name sortKey="Bensignor, E" sort="Bensignor, E" uniqKey="Bensignor E" first="E." last="Bensignor">E. Bensignor</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Veterinary Dermatology Referral Service, Paris, France; Veterinary Dermatology Referral Service, Lomme</wicri:regionArea><wicri:noRegion>Lomme</wicri:noRegion><wicri:noRegion>Lomme</wicri:noRegion></affiliation></author><author><name sortKey="Guaguere, E" sort="Guaguere, E" uniqKey="Guaguere E" first="E." last="Guaguere">E. Guaguere</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Veterinary Dermatology Referral Service, Paris, France; Veterinary Dermatology Referral Service, Lomme</wicri:regionArea><wicri:noRegion>Lomme</wicri:noRegion><wicri:noRegion>Lomme</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Veterinary Dermatology</title><title level="j" type="alt">VETERINARY DERMATOLOGY</title><idno type="ISSN">0959-4493</idno><idno type="eISSN">1365-3164</idno><imprint><biblScope unit="vol">15</biblScope><biblScope unit="page" from="43">43</biblScope><biblScope unit="page" to="43">43</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2004-08">2004-08</date></imprint><idno type="ISSN">0959-4493</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0959-4493</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The purpose of this study was to determine whether doxycycline (Ronaxan) decreased the severity of localized lesions of canine acne. Dogs were enrolled if they exhibited skin lesions localized to the chin compatible with canine acne, and if cytological smears showed a bacterial invasion and bacteriological samples grew Staphylococcus intermedius colonies. Demodicosis and dermatophytosis were excluded by skin scrapings and fungal culture, respectively. Lesions (erythema, lichenification, papules, pustules and excoriations) were graded with a quantitative 4‐point scale (maximal total score 15). Extent of lesion was also estimated. Pruritus was graded on a 4‐point scale. Scores were given at the time of inclusion and at day 30 after treatment with doxycycline 10 mg/kg once daily. Twelve dogs (10 males and two females) representing seven breeds were included. Good improvement of both lesional (9.4 before treatment and 2.3 after treatment) and extent scores (43% before treatment and 8% after treatment) was achieved. Pruritus was also markedly improved from 2.08 before treatment to 0.42 after treatment. One dog was not significantly improved after 1 month. Results of this trial suggest that doxycyline is useful for reducing the severity of localized skin lesions of canine acne. Funding: Self‐funded.</div></front></TEI><affiliations><list><country><li>France</li></country></list><tree><country name="France"><noRegion><name sortKey="Bensignor, E" sort="Bensignor, E" uniqKey="Bensignor E" first="E." last="Bensignor">E. Bensignor</name></noRegion><name sortKey="Guaguere, E" sort="Guaguere, E" uniqKey="Guaguere E" first="E." last="Guaguere">E. Guaguere</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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