Eccrine porocarcinoma
Identifieur interne : 001124 ( Istex/Checkpoint ); précédent : 001123; suivant : 001125Eccrine porocarcinoma
Auteurs : Clarence William Brown Jr [États-Unis] ; Lady Christine Dy [États-Unis]Source :
- Dermatologic Therapy [ 1396-0296 ] ; 2008-11.
Abstract
ABSTRACT: Eccrine porocarcinoma (EPC) is a rare cutaneous neoplasm that grows slowly over a long period of time but often experiences an accelerated growth phase. This malignant tumor may arise denovo or evolve from a pre‐existing benign eccrine poroma. Histologic evaluation demonstrates anaplastic cells involving the epidermis and infiltrating the dermis. Metastasis to regional lymph nodes distally occurs in a significant number of cases. Treatment modalities have included standard excision, Mohs micrographic surgery (MMS), chemotherapy, and radiation therapy. Recently sentinel lymph node biopsy has begun to be investigated as a staging tool. The literature on EPC is reviewed with attention paid to which of the various therapeutic options offers a clear advantage over the others. MMS affords the greatest likelihood of clear margins and cure in absence of regional and distant metastases.
Url:
DOI: 10.1111/j.1529-8019.2008.00243.x
Affiliations:
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