Childhood and adolescent orofacial granulomatosis is strongly associated with Crohn's disease and responds to intralesional corticosteroids
Identifieur interne : 000B11 ( Istex/Checkpoint ); précédent : 000B10; suivant : 000B12Childhood and adolescent orofacial granulomatosis is strongly associated with Crohn's disease and responds to intralesional corticosteroids
Auteurs : Alana J. Tuxen [Australie] ; David Orchard [Australie]Source :
- Australasian Journal of Dermatology [ 0004-8380 ] ; 2010-05.
Abstract
We present seven cases of orofacial granulomatosis occurring in paediatric patients aged 6–16 years. All patients were investigated for Crohn's disease and a strong association was found. All patients were treated with intralesional corticosteroid injections with excellent clinical responses. We review the literature and discuss the epidemiological association between childhood orofacial granulomatosis and Crohn's disease, as well as various treatment options, and propose a treatment protocol that was efficacious and well tolerated in all our patients.
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DOI: 10.1111/j.1440-0960.2010.00627.x
Affiliations:
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<front><div type="abstract" xml:lang="en">We present seven cases of orofacial granulomatosis occurring in paediatric patients aged 6–16 years. All patients were investigated for Crohn's disease and a strong association was found. All patients were treated with intralesional corticosteroid injections with excellent clinical responses. We review the literature and discuss the epidemiological association between childhood orofacial granulomatosis and Crohn's disease, as well as various treatment options, and propose a treatment protocol that was efficacious and well tolerated in all our patients.</div>
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