LymphedemaV1, France, Analysis, bibRecord, 000A03

[Conservative surgery after radiotherapy with preoperative doses in the treatment of breast cancer].

Identifieur interne : 000A03 ( France/Analysis ); précédent : 000A02; suivant : 000A04

[Conservative surgery after radiotherapy with preoperative doses in the treatment of breast cancer].

Auteurs : E. Darai [France] ; V. Mosseri ; J P Hamelin ; R J Salmon ; I. Karaitianos ; P. Bataini ; G. Mathieu ; R J Vilcoq ; J C Durand

Source :

Presse medicale (Paris, France : 1983) [ 0755-4982 ] ; 1991.

RBID : pubmed:1837363

Descripteurs français

KwdFr :
- Adulte, Adulte d'âge moyen, Association thérapeutique, Facteurs temps, Femelle, Humains, Lymphadénectomie, Mastectomie partielle (), Mastectomie partielle (effets indésirables), Récidive tumorale locale, Soins préopératoires, Sujet âgé, Sujet âgé de 80 ans ou plus, Tumeurs du sein (), Tumeurs du sein (anatomopathologie), Tumeurs du sein (radiothérapie), Études de suivi.
MESH :
- anatomopathologie : Tumeurs du sein.
- effets indésirables : Mastectomie partielle.
- radiothérapie : Tumeurs du sein.
- Adulte, Adulte d'âge moyen, Association thérapeutique, Facteurs temps, Femelle, Humains, Lymphadénectomie, Mastectomie partielle, Récidive tumorale locale, Soins préopératoires, Sujet âgé, Sujet âgé de 80 ans ou plus, Tumeurs du sein, Études de suivi.

English descriptors

KwdEn :
- Adult, Aged, Aged, 80 and over, Breast Neoplasms (pathology), Breast Neoplasms (radiotherapy), Breast Neoplasms (therapy), Combined Modality Therapy, Female, Follow-Up Studies, Humans, Lymph Node Excision, Mastectomy, Segmental (adverse effects), Mastectomy, Segmental (methods), Middle Aged, Neoplasm Recurrence, Local, Preoperative Care, Time Factors.
MESH :
- adverse effects : Mastectomy, Segmental.
- methods : Mastectomy, Segmental.
- pathology : Breast Neoplasms.
- radiotherapy : Breast Neoplasms.
- therapy : Breast Neoplasms.
- Adult, Aged, Aged, 80 and over, Combined Modality Therapy, Female, Follow-Up Studies, Humans, Lymph Node Excision, Middle Aged, Neoplasm Recurrence, Local, Preoperative Care, Time Factors.

Abstract

Radiotherapy as primary treatment is one of the means of increasing the rate of conservative treatment in patients with a breast tumour more than 3 cm in diameter. Between 1980 and 1986, 232 patients were treated in the Curie Institute by irradiation followed by conservative surgery for T2NO or T2N1a tumours wider than 3 cm, which accounted for 66 percent of the cases; 126 of these 232 tumours were located in the upper and outer quadrant. Axillary dissection was combined with tumoral excision in 63 percent of the cases. Conservative surgery was performed in patients who, after preoperative irradiation (50 Gy), had a persistent tumour less than 3 cm in diameter. Tumorectomy was complete in 96 percent of the cases, and the operative specimen was sterilized in 20 percent. The mean follow-up period was 46 months. The overall survival rate was 83 percent at 5 years (91 percent for T2NON1a). No local recurrence was observed in 92 percent of the patients at 3 years and 87 percent at 5 years. Nine percent of these women developed lymphoedema of the upper limb. The cosmetic result was good in 70 percent of the cases, fair in 25 percent and poor in 5 percent. The survival rate being the same with this treatment as with mastectomy, and the local recurrence rate being relatively low (13 percent at 5 years), we feel authorized to suggest that this post-radiotherapy conservative surgery should be used, at least in women with T2NON1a breast cancer.

PubMed: 1837363

Affiliations:

Links to Exploration step

pubmed:1837363

Le document en format XML

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<affiliation wicri:level="3"><nlm:affiliation>Institut Curie, Paris.</nlm:affiliation>
<country>France</country>
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<wicri:orgArea>Institut Curie</wicri:orgArea>
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<author><name sortKey="Mosseri, V" sort="Mosseri, V" uniqKey="Mosseri V" first="V" last="Mosseri">V. Mosseri</name>
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<author><name sortKey="Hamelin, J P" sort="Hamelin, J P" uniqKey="Hamelin J" first="J P" last="Hamelin">J P Hamelin</name>
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<author><name sortKey="Salmon, R J" sort="Salmon, R J" uniqKey="Salmon R" first="R J" last="Salmon">R J Salmon</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Breast Neoplasms (pathology)</term>
<term>Breast Neoplasms (radiotherapy)</term>
<term>Breast Neoplasms (therapy)</term>
<term>Combined Modality Therapy</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Lymph Node Excision</term>
<term>Mastectomy, Segmental (adverse effects)</term>
<term>Mastectomy, Segmental (methods)</term>
<term>Middle Aged</term>
<term>Neoplasm Recurrence, Local</term>
<term>Preoperative Care</term>
<term>Time Factors</term>
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<term>Adulte d'âge moyen</term>
<term>Association thérapeutique</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphadénectomie</term>
<term>Mastectomie partielle ()</term>
<term>Mastectomie partielle (effets indésirables)</term>
<term>Récidive tumorale locale</term>
<term>Soins préopératoires</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Tumeurs du sein ()</term>
<term>Tumeurs du sein (anatomopathologie)</term>
<term>Tumeurs du sein (radiothérapie)</term>
<term>Études de suivi</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Mastectomy, Segmental</term>
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<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Mastectomie partielle</term>
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<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Mastectomy, Segmental</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Breast Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="radiotherapy" xml:lang="en"><term>Breast Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="radiothérapie" xml:lang="fr"><term>Tumeurs du sein</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Combined Modality Therapy</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Lymph Node Excision</term>
<term>Middle Aged</term>
<term>Neoplasm Recurrence, Local</term>
<term>Preoperative Care</term>
<term>Time Factors</term>
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<term>Adulte d'âge moyen</term>
<term>Association thérapeutique</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphadénectomie</term>
<term>Mastectomie partielle</term>
<term>Récidive tumorale locale</term>
<term>Soins préopératoires</term>
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<front><div type="abstract" xml:lang="en">Radiotherapy as primary treatment is one of the means of increasing the rate of conservative treatment in patients with a breast tumour more than 3 cm in diameter. Between 1980 and 1986, 232 patients were treated in the Curie Institute by irradiation followed by conservative surgery for T2NO or T2N1a tumours wider than 3 cm, which accounted for 66 percent of the cases; 126 of these 232 tumours were located in the upper and outer quadrant. Axillary dissection was combined with tumoral excision in 63 percent of the cases. Conservative surgery was performed in patients who, after preoperative irradiation (50 Gy), had a persistent tumour less than 3 cm in diameter. Tumorectomy was complete in 96 percent of the cases, and the operative specimen was sterilized in 20 percent. The mean follow-up period was 46 months. The overall survival rate was 83 percent at 5 years (91 percent for T2NON1a). No local recurrence was observed in 92 percent of the patients at 3 years and 87 percent at 5 years. Nine percent of these women developed lymphoedema of the upper limb. The cosmetic result was good in 70 percent of the cases, fair in 25 percent and poor in 5 percent. The survival rate being the same with this treatment as with mastectomy, and the local recurrence rate being relatively low (13 percent at 5 years), we feel authorized to suggest that this post-radiotherapy conservative surgery should be used, at least in women with T2NON1a breast cancer.</div>
</front>
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Serveur d'exploration sur le lymphœdème

[Conservative surgery after radiotherapy with preoperative doses in the treatment of breast cancer].

[Conservative surgery after radiotherapy with preoperative doses in the treatment of breast cancer].

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
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