[Genetics of lymphedema: from Milroy's disease to cancer investigations].
Identifieur interne : 000644 ( France/Analysis ); précédent : 000643; suivant : 000645[Genetics of lymphedema: from Milroy's disease to cancer investigations].
Auteurs : I. Quéré [France] ; M. Coupé ; V. Soulier-Sotto ; M. Evrard-Bras ; J P Laroche ; C. JanbonSource :
- La Revue de medecine interne [ 0248-8663 ] ; 2002.
Descripteurs français
- KwdFr :
- Facteur de croissance endothéliale vasculaire de type C, Facteur de croissance endothéliale vasculaire de type D, Facteurs de croissance endothéliale (génétique), Facteurs de croissance endothéliale (pharmacologie), Humains, Ligands, Lymphe, Lymphoedème (génétique), Lymphoedème (physiopathologie), Métastase tumorale, Tumeurs ().
- MESH :
- génétique : Facteurs de croissance endothéliale, Lymphoedème.
- pharmacologie : Facteurs de croissance endothéliale.
- physiopathologie : Lymphoedème.
- Facteur de croissance endothéliale vasculaire de type C, Facteur de croissance endothéliale vasculaire de type D, Humains, Ligands, Lymphe, Métastase tumorale, Tumeurs.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : Endothelial Growth Factors.
- chemical , pharmacology : Endothelial Growth Factors.
- complications : Neoplasms.
- genetics : Lymphedema.
- physiopathology : Lymphedema.
- Humans, Ligands, Lymph, Neoplasm Metastasis, Vascular Endothelial Growth Factor C, Vascular Endothelial Growth Factor D.
Abstract
New insight has recently been obtained into the molecular mechanisms regulating lymphatic development and function during embryogenesis. VEGF-C and D ligands have been shown to stimulate lymphangiogenesis and their lymphatic-specific receptor VEGFR-3 is linked to the human congenital and hereditary lymphedema in humans. Above all, new focus on lymphatic endothelial cells gives opportunities for developing innovative therapies for lymphedema and cancer metastasis.
PubMed: 12162200
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 004514
- to stream PubMed, to step Curation: 004514
- to stream PubMed, to step Checkpoint: 004514
- to stream Ncbi, to step Merge: 000A57
- to stream Ncbi, to step Curation: 000A57
- to stream Ncbi, to step Checkpoint: 000A57
- to stream Main, to step Merge: 009637
- to stream Main, to step Curation: 009318
- to stream Main, to step Exploration: 009318
- to stream France, to step Extraction: 000644
Links to Exploration step
pubmed:12162200Le document en format XML
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<front><div type="abstract" xml:lang="en">New insight has recently been obtained into the molecular mechanisms regulating lymphatic development and function during embryogenesis. VEGF-C and D ligands have been shown to stimulate lymphangiogenesis and their lymphatic-specific receptor VEGFR-3 is linked to the human congenital and hereditary lymphedema in humans. Above all, new focus on lymphatic endothelial cells gives opportunities for developing innovative therapies for lymphedema and cancer metastasis.</div>
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