Stopping the COVID-19 Pandemic: A Review on the Advances of Diagnosis, Treatment, and Control Measures.
Identifieur interne : 000F32 ( Main/Corpus ); précédent : 000F31; suivant : 000F33Stopping the COVID-19 Pandemic: A Review on the Advances of Diagnosis, Treatment, and Control Measures.
Auteurs : Md Hasanul Banna Siam ; Nahida Hannan Nishat ; Ahsan Ahmed ; Mohammad Sorowar HossainSource :
- Journal of pathogens [ 2090-3057 ] ; 2020.
Abstract
With the continued spread of COVID-19 across the world, rapid diagnostic tools, readily available respurposable drugs, and prompt containment measures to control the SARS-CoV-2 infection are of paramount importance. Examples of recent advances in diagnostic tests are CRISPR technology, IgG assay, spike protein detection, and use of artificial intelligence. The gold standard reverse transcription polymerase chain (RT-PCR) has also been upgraded with point-of-care rapid tests. Supportive treatment, mechanical ventilation, and extracorporeal membrane oxygenation (ECMO) remain the primary choice, while therapeutic options include antivirals, antiparasitics, anti-inflammatories, interferon, convalescent plasma, monoclonal antibody, hyperimmunoglobulin, RNAi, and mesenchymal stem cell therapy. Different types of vaccines such as RNA, DNA, and lentiviral, inactivated, and viral vector are in clinical trials. Moreover, rapidly deployable and easy-to-transport innovative vaccine delivery systems are also in development. As countries have started easing down on the lockdown measures, the chance for a second wave of infection demands strict and rational control policies to keep fatalities minimized. An improved understanding of the advances in diagnostic tools, treatments, vaccines, and control measures for COVID-19 can provide references for further research and aid better containment strategies.
DOI: 10.1155/2020/9121429
PubMed: 33133697
PubMed Central: PMC7588828
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Examples of recent advances in diagnostic tests are CRISPR technology, IgG assay, spike protein detection, and use of artificial intelligence. The gold standard reverse transcription polymerase chain (RT-PCR) has also been upgraded with point-of-care rapid tests. Supportive treatment, mechanical ventilation, and extracorporeal membrane oxygenation (ECMO) remain the primary choice, while therapeutic options include antivirals, antiparasitics, anti-inflammatories, interferon, convalescent plasma, monoclonal antibody, hyperimmunoglobulin, RNAi, and mesenchymal stem cell therapy. Different types of vaccines such as RNA, DNA, and lentiviral, inactivated, and viral vector are in clinical trials. Moreover, rapidly deployable and easy-to-transport innovative vaccine delivery systems are also in development. As countries have started easing down on the lockdown measures, the chance for a second wave of infection demands strict and rational control policies to keep fatalities minimized. An improved understanding of the advances in diagnostic tools, treatments, vaccines, and control measures for COVID-19 can provide references for further research and aid better containment strategies.</div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">33133697</PMID><DateRevised><Year>2020</Year><Month>11</Month><Day>03</Day></DateRevised><Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Print">2090-3057</ISSN><JournalIssue CitedMedium="Print"><Volume>2020</Volume><PubDate><Year>2020</Year></PubDate></JournalIssue><Title>Journal of pathogens</Title><ISOAbbreviation>J Pathog</ISOAbbreviation></Journal><ArticleTitle>Stopping the COVID-19 Pandemic: A Review on the Advances of Diagnosis, Treatment, and Control Measures.</ArticleTitle><Pagination><MedlinePgn>9121429</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1155/2020/9121429</ELocationID><Abstract><AbstractText>With the continued spread of COVID-19 across the world, rapid diagnostic tools, readily available respurposable drugs, and prompt containment measures to control the SARS-CoV-2 infection are of paramount importance. Examples of recent advances in diagnostic tests are CRISPR technology, IgG assay, spike protein detection, and use of artificial intelligence. The gold standard reverse transcription polymerase chain (RT-PCR) has also been upgraded with point-of-care rapid tests. Supportive treatment, mechanical ventilation, and extracorporeal membrane oxygenation (ECMO) remain the primary choice, while therapeutic options include antivirals, antiparasitics, anti-inflammatories, interferon, convalescent plasma, monoclonal antibody, hyperimmunoglobulin, RNAi, and mesenchymal stem cell therapy. Different types of vaccines such as RNA, DNA, and lentiviral, inactivated, and viral vector are in clinical trials. Moreover, rapidly deployable and easy-to-transport innovative vaccine delivery systems are also in development. As countries have started easing down on the lockdown measures, the chance for a second wave of infection demands strict and rational control policies to keep fatalities minimized. An improved understanding of the advances in diagnostic tools, treatments, vaccines, and control measures for COVID-19 can provide references for further research and aid better containment strategies.</AbstractText><CopyrightInformation>Copyright © 2020 Md. Hasanul Banna Siam et al.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Siam</LastName><ForeName>Md Hasanul Banna</ForeName><Initials>MHB</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-5883-2841</Identifier><AffiliationInfo><Affiliation>Biomedical Research Foundation (BRF), Dhaka, Bangladesh.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Microbiology, University of Dhaka, Dhaka, Bangladesh.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nishat</LastName><ForeName>Nahida Hannan</ForeName><Initials>NH</Initials><Identifier Source="ORCID">https://orcid.org/0000-0001-5830-2261</Identifier><AffiliationInfo><Affiliation>Biomedical Research Foundation (BRF), Dhaka, Bangladesh.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Dhaka Medical College Hospital, Dhaka, Bangladesh.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ahmed</LastName><ForeName>Ahsan</ForeName><Initials>A</Initials><Identifier Source="ORCID">https://orcid.org/0000-0003-3121-8769</Identifier><AffiliationInfo><Affiliation>Biomedical Research Foundation (BRF), Dhaka, Bangladesh.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Dhaka Medical College Hospital, Dhaka, Bangladesh.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hossain</LastName><ForeName>Mohammad Sorowar</ForeName><Initials>MS</Initials><Identifier Source="ORCID">https://orcid.org/0000-0001-7143-2909</Identifier><AffiliationInfo><Affiliation>Biomedical Research Foundation (BRF), Dhaka, Bangladesh.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>School of Environment and Life Science, Independent University Bangladesh (IUB), Dhaka, Bangladesh.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal 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