JankovicV1, PubMed, Curation, bibRecord, 000039

Falls in Parkinson disease: analysis of a large cross-sectional cohort.

Identifieur interne : 000039 ( PubMed/Curation ); précédent : 000038; suivant : 000040

Falls in Parkinson disease: analysis of a large cross-sectional cohort.

Auteurs : Sotirios. Parashos [États-Unis] ; Catherine. Wielinski ; Nir Giladi ; Tanya Gurevich

Source :

Journal of Parkinson's disease ; 2013.

RBID : pubmed:24113557

Descripteurs français

Wicri :
- geographic : États-Unis.

English descriptors

KwdEn :
- Accidental Falls (statistics & numerical data), Aged, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Parkinson Disease (epidemiology), Prospective Studies, Risk Factors, United States (epidemiology).
MESH :
- geographic , epidemiology : United States.
- epidemiology : Parkinson Disease.
- statistics & numerical data : Accidental Falls.
- Aged, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Prospective Studies, Risk Factors.

Abstract

Falls remain a significant cause of morbidity in PD. Risk factors are not well understood.

DOI: 10.3233/JPD-130249
PubMed: 24113557

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Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Falls in Parkinson disease: analysis of a large cross-sectional cohort.</title>
<author><name sortKey="Parashos, Sotirios A" sort="Parashos, Sotirios A" uniqKey="Parashos S" first="Sotirios" last="Parashos">Sotirios. Parashos</name>
<affiliation wicri:level="1"><nlm:affiliation>Struthers Parkinson's Center, Golden Valley, MN, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Struthers Parkinson's Center, Golden Valley, MN</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wielinski, Catherine L" sort="Wielinski, Catherine L" uniqKey="Wielinski C" first="Catherine" last="Wielinski">Catherine. Wielinski</name>
</author>
<author><name sortKey="Giladi, Nir" sort="Giladi, Nir" uniqKey="Giladi N" first="Nir" last="Giladi">Nir Giladi</name>
</author>
<author><name sortKey="Gurevich, Tanya" sort="Gurevich, Tanya" uniqKey="Gurevich T" first="Tanya" last="Gurevich">Tanya Gurevich</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2013">2013</date>
<idno type="RBID">pubmed:24113557</idno>
<idno type="pmid">24113557</idno>
<idno type="doi">10.3233/JPD-130249</idno>
<idno type="wicri:Area/PubMed/Corpus">000039</idno>
<idno type="wicri:Area/PubMed/Curation">000039</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Falls in Parkinson disease: analysis of a large cross-sectional cohort.</title>
<author><name sortKey="Parashos, Sotirios A" sort="Parashos, Sotirios A" uniqKey="Parashos S" first="Sotirios" last="Parashos">Sotirios. Parashos</name>
<affiliation wicri:level="1"><nlm:affiliation>Struthers Parkinson's Center, Golden Valley, MN, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Struthers Parkinson's Center, Golden Valley, MN</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wielinski, Catherine L" sort="Wielinski, Catherine L" uniqKey="Wielinski C" first="Catherine" last="Wielinski">Catherine. Wielinski</name>
</author>
<author><name sortKey="Giladi, Nir" sort="Giladi, Nir" uniqKey="Giladi N" first="Nir" last="Giladi">Nir Giladi</name>
</author>
<author><name sortKey="Gurevich, Tanya" sort="Gurevich, Tanya" uniqKey="Gurevich T" first="Tanya" last="Gurevich">Tanya Gurevich</name>
</author>
</analytic>
<series><title level="j">Journal of Parkinson's disease</title>
<idno type="e-ISSN">1877-718X</idno>
<imprint><date when="2013" type="published">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Accidental Falls (statistics & numerical data)</term>
<term>Aged</term>
<term>Cross-Sectional Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (epidemiology)</term>
<term>Prospective Studies</term>
<term>Risk Factors</term>
<term>United States (epidemiology)</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>United States</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Accidental Falls</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Cross-Sectional Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
<term>Risk Factors</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>États-Unis</term>
</keywords>
</textClass>
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<front><div type="abstract" xml:lang="en">Falls remain a significant cause of morbidity in PD. Risk factors are not well understood.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">24113557</PMID>
<DateCreated><Year>2013</Year>
<Month>12</Month>
<Day>10</Day>
</DateCreated>
<DateCompleted><Year>2014</Year>
<Month>08</Month>
<Day>25</Day>
</DateCompleted>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1877-718X</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>3</Volume>
<Issue>4</Issue>
<PubDate><Year>2013</Year>
</PubDate>
</JournalIssue>
<Title>Journal of Parkinson's disease</Title>
<ISOAbbreviation>J Parkinsons Dis</ISOAbbreviation>
</Journal>
<ArticleTitle>Falls in Parkinson disease: analysis of a large cross-sectional cohort.</ArticleTitle>
<Pagination><MedlinePgn>515-22</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.3233/JPD-130249</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Falls remain a significant cause of morbidity in PD. Risk factors are not well understood.</AbstractText>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">In this study we explore risk factors for falls in PD utilizing the cross-sectional, baseline data in the National Parkinson Foundation Quality Improvement Initiative (NPF-QII) database. Subjects are being followed prospectively, and this study will provide the basis for subsequent longitudinal analyses.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">A cross-sectional analysis of data from 2,876 ambulatory patients with Parkinson disease enrolled in the NPF-QII at 18 sites. Main outcome measure was falling history in the 3 months preceding assessment. The following were considered as possible predictor variables: age, sex, height, weight, body mass index, disease duration, age at disease onset, investigator's confidence in the diagnosis, Hoehn and Yahr stage, rest tremor, ability to stand unassisted, coexistent pathologies (cardiovascular, respiratory, diabetes, cancer, neurological, osteoarthritis, and "other" comorbidities), anticholinergics, antidepressants, antipsychotics, cognitive enhancers, deep brain stimulation surgery, timed-up-and-go, semantic fluency, and 5 word recall. Variables with associations to the outcome measure in univariate analyses were analyzed in multivariable models using logistic regression.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">37.2% of subjects experienced falls. In the multivariable regression model the following variables were found to be independently associated with falls: disease duration; Hoehn and Yahr stage; absence of rest tremor; cardiovascular, arthritis, or "other" comorbidity; antidepressants; deep brain stimulation surgery; timed-up-and-go; and, semantic fluency.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Disease duration but not age is independently associated with falls in Parkinson disease. Timed-up-and-go accurately reflects falls risk. Impaired semantic fluency is independently associated with falls, while verbal memory is not. Comorbidities, antidepressants, and deep brain stimulation also contribute to falls risk.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Parashos</LastName>
<ForeName>Sotirios A</ForeName>
<Initials>SA</Initials>
<AffiliationInfo><Affiliation>Struthers Parkinson's Center, Golden Valley, MN, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wielinski</LastName>
<ForeName>Catherine L</ForeName>
<Initials>CL</Initials>
</Author>
<Author ValidYN="Y"><LastName>Giladi</LastName>
<ForeName>Nir</ForeName>
<Initials>N</Initials>
</Author>
<Author ValidYN="Y"><LastName>Gurevich</LastName>
<ForeName>Tanya</ForeName>
<Initials>T</Initials>
</Author>
<Author ValidYN="Y"><CollectiveName>National Parkinson Foundation Quality Improvement Initiative Investigators</CollectiveName>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D016448">Multicenter Study</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
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</Article>
<MedlineJournalInfo><Country>Netherlands</Country>
<MedlineTA>J Parkinsons Dis</MedlineTA>
<NlmUniqueID>101567362</NlmUniqueID>
<ISSNLinking>1877-7171</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000058">Accidental Falls</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000706">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D003430">Cross-Sectional Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D010300">Parkinson Disease</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000453">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D011446">Prospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D012307">Risk Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" Type="Geographic" UI="D014481">United States</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000453">epidemiology</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Parkinson disease</Keyword>
<Keyword MajorTopicYN="N">antidepressants</Keyword>
<Keyword MajorTopicYN="N">cognitive dysfunction</Keyword>
<Keyword MajorTopicYN="N">falls</Keyword>
</KeywordList>
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<ForeName>Bastiaan</ForeName>
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<Investigator ValidYN="Y"><LastName>Brandabur</LastName>
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<Investigator ValidYN="Y"><LastName>Cheng</LastName>
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Serveur d'exploration autour de Joseph Jankovic

Falls in Parkinson disease: analysis of a large cross-sectional cohort.

Falls in Parkinson disease: analysis of a large cross-sectional cohort.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki