JankovicV1, PubMed, Corpus, bibRecord, 000250

Alcohol dehydrogenase polymorphism and Parkinson's disease.

Identifieur interne : 000250 ( PubMed/Corpus ); précédent : 000249; suivant : 000251

Alcohol dehydrogenase polymorphism and Parkinson's disease.

Auteurs : E Tan ; S. Nagamitsu ; T. Matsuura ; M. Khajavi ; J. Jankovic ; W. Ondo ; T. Ashizawa

Source :

Neuroscience letters [ 0304-3940 ] ; 2001.

RBID : pubmed:11356310

English descriptors

KwdEn :
- Adult, Aged, Aged, 80 and over, Alcohol Dehydrogenase (genetics), Alleles, Case-Control Studies, Gene Frequency, Genetic Predisposition to Disease, Humans, Huntington Disease (genetics), Isoenzymes (genetics), Linkage Disequilibrium, Middle Aged, Parkinson Disease (genetics), Polymorphism, Genetic (physiology), Reference Values, Tremor (genetics).
MESH :
- chemical , genetics : Alcohol Dehydrogenase, Isoenzymes.
- genetics : Huntington Disease, Parkinson Disease, Tremor.
- physiology : Polymorphism, Genetic.
- Adult, Aged, Aged, 80 and over, Alleles, Case-Control Studies, Gene Frequency, Genetic Predisposition to Disease, Humans, Linkage Disequilibrium, Middle Aged, Reference Values.

Abstract

A particular alcohol dehydrogenase (ADH) polymorphism (allele A1) in the promoter region of the gene has been recently demonstrated to be associated with increased risk of Parkinson's disease (PD). In a case control study, we examine frequencies of ADH A1 allele in 100 PD patients (i.e. 200 alleles), 100 diseased controls (i.e. 200 alleles), and 194 healthy controls (i.e. 388 alleles). In addition, we study possible association of a combined non-amyloid component of plaque (NACP-Rep 1) allele and ADH A1 allele with risk of PD. There was no statistical significance of the frequencies of ADH A1 allele between PD patients 12/200 (6%), diseased controls 13/200 (6.5%), and healthy controls 20/388 (5.2%). No strong evidence of an association was found between ADH A1 allele and PD susceptibility in our study patients. There was also no suggestion of linkage disequilibrium between NACP-Rep 1 and ADH A1 alleles.

PubMed: 11356310

Links to Exploration step

pubmed:11356310

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Alcohol dehydrogenase polymorphism and Parkinson's disease.</title>
<author><name sortKey="Tan, E K" sort="Tan, E K" uniqKey="Tan E" first="E" last="Tan">E Tan</name>
<affiliation><nlm:affiliation>Department of Neurology, VA Medical Center, Baylor College of Medicine, Houston, TX, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Nagamitsu, S" sort="Nagamitsu, S" uniqKey="Nagamitsu S" first="S" last="Nagamitsu">S. Nagamitsu</name>
</author>
<author><name sortKey="Matsuura, T" sort="Matsuura, T" uniqKey="Matsuura T" first="T" last="Matsuura">T. Matsuura</name>
</author>
<author><name sortKey="Khajavi, M" sort="Khajavi, M" uniqKey="Khajavi M" first="M" last="Khajavi">M. Khajavi</name>
</author>
<author><name sortKey="Jankovic, J" sort="Jankovic, J" uniqKey="Jankovic J" first="J" last="Jankovic">J. Jankovic</name>
</author>
<author><name sortKey="Ondo, W" sort="Ondo, W" uniqKey="Ondo W" first="W" last="Ondo">W. Ondo</name>
</author>
<author><name sortKey="Ashizawa, T" sort="Ashizawa, T" uniqKey="Ashizawa T" first="T" last="Ashizawa">T. Ashizawa</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2001">2001</date>
<idno type="RBID">pubmed:11356310</idno>
<idno type="pmid">11356310</idno>
<idno type="wicri:Area/PubMed/Corpus">000250</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Alcohol dehydrogenase polymorphism and Parkinson's disease.</title>
<author><name sortKey="Tan, E K" sort="Tan, E K" uniqKey="Tan E" first="E" last="Tan">E Tan</name>
<affiliation><nlm:affiliation>Department of Neurology, VA Medical Center, Baylor College of Medicine, Houston, TX, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Nagamitsu, S" sort="Nagamitsu, S" uniqKey="Nagamitsu S" first="S" last="Nagamitsu">S. Nagamitsu</name>
</author>
<author><name sortKey="Matsuura, T" sort="Matsuura, T" uniqKey="Matsuura T" first="T" last="Matsuura">T. Matsuura</name>
</author>
<author><name sortKey="Khajavi, M" sort="Khajavi, M" uniqKey="Khajavi M" first="M" last="Khajavi">M. Khajavi</name>
</author>
<author><name sortKey="Jankovic, J" sort="Jankovic, J" uniqKey="Jankovic J" first="J" last="Jankovic">J. Jankovic</name>
</author>
<author><name sortKey="Ondo, W" sort="Ondo, W" uniqKey="Ondo W" first="W" last="Ondo">W. Ondo</name>
</author>
<author><name sortKey="Ashizawa, T" sort="Ashizawa, T" uniqKey="Ashizawa T" first="T" last="Ashizawa">T. Ashizawa</name>
</author>
</analytic>
<series><title level="j">Neuroscience letters</title>
<idno type="ISSN">0304-3940</idno>
<imprint><date when="2001" type="published">2001</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Alcohol Dehydrogenase (genetics)</term>
<term>Alleles</term>
<term>Case-Control Studies</term>
<term>Gene Frequency</term>
<term>Genetic Predisposition to Disease</term>
<term>Humans</term>
<term>Huntington Disease (genetics)</term>
<term>Isoenzymes (genetics)</term>
<term>Linkage Disequilibrium</term>
<term>Middle Aged</term>
<term>Parkinson Disease (genetics)</term>
<term>Polymorphism, Genetic (physiology)</term>
<term>Reference Values</term>
<term>Tremor (genetics)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Alcohol Dehydrogenase</term>
<term>Isoenzymes</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Huntington Disease</term>
<term>Parkinson Disease</term>
<term>Tremor</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Polymorphism, Genetic</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Alleles</term>
<term>Case-Control Studies</term>
<term>Gene Frequency</term>
<term>Genetic Predisposition to Disease</term>
<term>Humans</term>
<term>Linkage Disequilibrium</term>
<term>Middle Aged</term>
<term>Reference Values</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">A particular alcohol dehydrogenase (ADH) polymorphism (allele A1) in the promoter region of the gene has been recently demonstrated to be associated with increased risk of Parkinson's disease (PD). In a case control study, we examine frequencies of ADH A1 allele in 100 PD patients (i.e. 200 alleles), 100 diseased controls (i.e. 200 alleles), and 194 healthy controls (i.e. 388 alleles). In addition, we study possible association of a combined non-amyloid component of plaque (NACP-Rep 1) allele and ADH A1 allele with risk of PD. There was no statistical significance of the frequencies of ADH A1 allele between PD patients 12/200 (6%), diseased controls 13/200 (6.5%), and healthy controls 20/388 (5.2%). No strong evidence of an association was found between ADH A1 allele and PD susceptibility in our study patients. There was also no suggestion of linkage disequilibrium between NACP-Rep 1 and ADH A1 alleles.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">11356310</PMID>
<DateCreated><Year>2001</Year>
<Month>05</Month>
<Day>17</Day>
</DateCreated>
<DateCompleted><Year>2001</Year>
<Month>08</Month>
<Day>23</Day>
</DateCompleted>
<DateRevised><Year>2004</Year>
<Month>11</Month>
<Day>17</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0304-3940</ISSN>
<JournalIssue CitedMedium="Print"><Volume>305</Volume>
<Issue>1</Issue>
<PubDate><Year>2001</Year>
<Month>Jun</Month>
<Day>1</Day>
</PubDate>
</JournalIssue>
<Title>Neuroscience letters</Title>
<ISOAbbreviation>Neurosci. Lett.</ISOAbbreviation>
</Journal>
<ArticleTitle>Alcohol dehydrogenase polymorphism and Parkinson's disease.</ArticleTitle>
<Pagination><MedlinePgn>70-2</MedlinePgn>
</Pagination>
<Abstract><AbstractText>A particular alcohol dehydrogenase (ADH) polymorphism (allele A1) in the promoter region of the gene has been recently demonstrated to be associated with increased risk of Parkinson's disease (PD). In a case control study, we examine frequencies of ADH A1 allele in 100 PD patients (i.e. 200 alleles), 100 diseased controls (i.e. 200 alleles), and 194 healthy controls (i.e. 388 alleles). In addition, we study possible association of a combined non-amyloid component of plaque (NACP-Rep 1) allele and ADH A1 allele with risk of PD. There was no statistical significance of the frequencies of ADH A1 allele between PD patients 12/200 (6%), diseased controls 13/200 (6.5%), and healthy controls 20/388 (5.2%). No strong evidence of an association was found between ADH A1 allele and PD susceptibility in our study patients. There was also no suggestion of linkage disequilibrium between NACP-Rep 1 and ADH A1 alleles.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tan</LastName>
<ForeName>E K</ForeName>
<Initials>EK</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, VA Medical Center, Baylor College of Medicine, Houston, TX, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Nagamitsu</LastName>
<ForeName>S</ForeName>
<Initials>S</Initials>
</Author>
<Author ValidYN="Y"><LastName>Matsuura</LastName>
<ForeName>T</ForeName>
<Initials>T</Initials>
</Author>
<Author ValidYN="Y"><LastName>Khajavi</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>Jankovic</LastName>
<ForeName>J</ForeName>
<Initials>J</Initials>
</Author>
<Author ValidYN="Y"><LastName>Ondo</LastName>
<ForeName>W</ForeName>
<Initials>W</Initials>
</Author>
<Author ValidYN="Y"><LastName>Ashizawa</LastName>
<ForeName>T</ForeName>
<Initials>T</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>Ireland</Country>
<MedlineTA>Neurosci Lett</MedlineTA>
<NlmUniqueID>7600130</NlmUniqueID>
<ISSNLinking>0304-3940</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D007527">Isoenzymes</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 1.1.1.1</RegistryNumber>
<NameOfSubstance UI="D000426">Alcohol Dehydrogenase</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D000369">Aged, 80 and over</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D000426">Alcohol Dehydrogenase</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000235">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D000483">Alleles</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D016022">Case-Control Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005787">Gene Frequency</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D020022">Genetic Predisposition to Disease</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006816">Huntington Disease</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D007527">Isoenzymes</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000235">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D015810">Linkage Disequilibrium</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D010300">Parkinson Disease</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000235">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D011110">Polymorphism, Genetic</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000502">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D012016">Reference Values</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D014202">Tremor</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2001</Year>
<Month>5</Month>
<Day>18</Day>
<Hour>10</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2001</Year>
<Month>8</Month>
<Day>24</Day>
<Hour>10</Hour>
<Minute>1</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2001</Year>
<Month>5</Month>
<Day>18</Day>
<Hour>10</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">11356310</ArticleId>
<ArticleId IdType="pii">S0304394001017700</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/JankovicV1/Data/PubMed/Corpus

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000250 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000250 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Santé
   |area=    JankovicV1
   |flux=    PubMed
   |étape=   Corpus
   |type=    RBID
   |clé=     pubmed:11356310
   |texte=   Alcohol dehydrogenase polymorphism and Parkinson's disease.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i   -Sk "pubmed:11356310" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd   \
       | NlmPubMed2Wicri -a JankovicV1

This area was generated with Dilib version V0.6.19.
Data generation: Wed Feb 10 22:03:07 2016. Site generation: Tue Feb 13 16:14:27 2024

	Serveur d'exploration autour de Joseph Jankovic
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration autour de Joseph Jankovic

Alcohol dehydrogenase polymorphism and Parkinson's disease.

Alcohol dehydrogenase polymorphism and Parkinson's disease.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki