Hemiparkinsonism-hemiatrophy syndrome.
Identifieur interne : 000152 ( PubMed/Corpus ); précédent : 000151; suivant : 000153Hemiparkinsonism-hemiatrophy syndrome.
Auteurs : Subhashie Wijemanne ; Joseph JankovicSource :
- Neurology ; 2007.
English descriptors
- KwdEn :
- Adolescent, Adult, Atrophy (complications), Atrophy (diagnosis), Atrophy (physiopathology), Birth Injuries (complications), Brain (pathology), Brain (physiopathology), Brain Damage, Chronic (complications), Brain Damage, Chronic (etiology), Brain Damage, Chronic (physiopathology), Dystonia (etiology), Dystonia (physiopathology), Extremities (pathology), Facial Hemiatrophy (complications), Facial Hemiatrophy (diagnosis), Facial Hemiatrophy (physiopathology), Female, Growth Disorders (complications), Growth Disorders (diagnosis), Growth Disorders (physiopathology), Humans, Magnetic Resonance Imaging, Male, Middle Aged, Muscle, Skeletal (physiopathology), Parkinson Disease (complications), Parkinson Disease (diagnosis), Parkinson Disease (physiopathology), Scoliosis (etiology), Scoliosis (physiopathology), Seizures, Febrile (complications), Syndrome.
- MESH :
- complications : Atrophy, Birth Injuries, Brain Damage, Chronic, Facial Hemiatrophy, Growth Disorders, Parkinson Disease, Seizures, Febrile.
- diagnosis : Atrophy, Facial Hemiatrophy, Growth Disorders, Parkinson Disease.
- etiology : Brain Damage, Chronic, Dystonia, Scoliosis.
- pathology : Brain, Extremities.
- physiopathology : Atrophy, Brain, Brain Damage, Chronic, Dystonia, Facial Hemiatrophy, Growth Disorders, Muscle, Skeletal, Parkinson Disease, Scoliosis.
- Adolescent, Adult, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Syndrome.
Abstract
To characterize the clinical and radiologic features of hemiparkinsonism-hemiatrophy syndrome (HPHA).
DOI: 10.1212/01.wnl.0000277699.48155.39
PubMed: 17938368
Links to Exploration step
pubmed:17938368Le document en format XML
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<author><name sortKey="Wijemanne, Subhashie" sort="Wijemanne, Subhashie" uniqKey="Wijemanne S" first="Subhashie" last="Wijemanne">Subhashie Wijemanne</name>
<affiliation><nlm:affiliation>Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Suite 1801, 6550 Fannin, Houston, TX 77030, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2007">2007</date>
<idno type="doi">10.1212/01.wnl.0000277699.48155.39</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Hemiparkinsonism-hemiatrophy syndrome.</title>
<author><name sortKey="Wijemanne, Subhashie" sort="Wijemanne, Subhashie" uniqKey="Wijemanne S" first="Subhashie" last="Wijemanne">Subhashie Wijemanne</name>
<affiliation><nlm:affiliation>Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Suite 1801, 6550 Fannin, Houston, TX 77030, USA.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name>
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<series><title level="j">Neurology</title>
<idno type="e-ISSN">1526-632X</idno>
<imprint><date when="2007" type="published">2007</date>
</imprint>
</series>
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</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Atrophy (complications)</term>
<term>Atrophy (diagnosis)</term>
<term>Atrophy (physiopathology)</term>
<term>Birth Injuries (complications)</term>
<term>Brain (pathology)</term>
<term>Brain (physiopathology)</term>
<term>Brain Damage, Chronic (complications)</term>
<term>Brain Damage, Chronic (etiology)</term>
<term>Brain Damage, Chronic (physiopathology)</term>
<term>Dystonia (etiology)</term>
<term>Dystonia (physiopathology)</term>
<term>Extremities (pathology)</term>
<term>Facial Hemiatrophy (complications)</term>
<term>Facial Hemiatrophy (diagnosis)</term>
<term>Facial Hemiatrophy (physiopathology)</term>
<term>Female</term>
<term>Growth Disorders (complications)</term>
<term>Growth Disorders (diagnosis)</term>
<term>Growth Disorders (physiopathology)</term>
<term>Humans</term>
<term>Magnetic Resonance Imaging</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Muscle, Skeletal (physiopathology)</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (diagnosis)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Scoliosis (etiology)</term>
<term>Scoliosis (physiopathology)</term>
<term>Seizures, Febrile (complications)</term>
<term>Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Atrophy</term>
<term>Birth Injuries</term>
<term>Brain Damage, Chronic</term>
<term>Facial Hemiatrophy</term>
<term>Growth Disorders</term>
<term>Parkinson Disease</term>
<term>Seizures, Febrile</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Atrophy</term>
<term>Facial Hemiatrophy</term>
<term>Growth Disorders</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Brain Damage, Chronic</term>
<term>Dystonia</term>
<term>Scoliosis</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain</term>
<term>Extremities</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Atrophy</term>
<term>Brain</term>
<term>Brain Damage, Chronic</term>
<term>Dystonia</term>
<term>Facial Hemiatrophy</term>
<term>Growth Disorders</term>
<term>Muscle, Skeletal</term>
<term>Parkinson Disease</term>
<term>Scoliosis</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Female</term>
<term>Humans</term>
<term>Magnetic Resonance Imaging</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Syndrome</term>
</keywords>
</textClass>
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</teiHeader>
<front><div type="abstract" xml:lang="en">To characterize the clinical and radiologic features of hemiparkinsonism-hemiatrophy syndrome (HPHA).</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">17938368</PMID>
<DateCreated><Year>2007</Year>
<Month>10</Month>
<Day>16</Day>
</DateCreated>
<DateCompleted><Year>2007</Year>
<Month>11</Month>
<Day>08</Day>
</DateCompleted>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1526-632X</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>69</Volume>
<Issue>16</Issue>
<PubDate><Year>2007</Year>
<Month>Oct</Month>
<Day>16</Day>
</PubDate>
</JournalIssue>
<Title>Neurology</Title>
<ISOAbbreviation>Neurology</ISOAbbreviation>
</Journal>
<ArticleTitle>Hemiparkinsonism-hemiatrophy syndrome.</ArticleTitle>
<Pagination><MedlinePgn>1585-94</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To characterize the clinical and radiologic features of hemiparkinsonism-hemiatrophy syndrome (HPHA).</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Medical records of patients with evidence of unilateral parkinsonism and ipsilateral body atrophy, evaluated at the Baylor College of Medicine Movement Disorders Clinic, were reviewed.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The mean age at onset of the 30 patients who satisfied the criteria was 44.2 (15 to 63) years with a mean duration of symptoms for 9.7 (2 to 20) years. Half of all patients had dystonia at onset and dystonia was present in 21 (70%) patients during the course of the syndrome. Eleven (37%) also had scoliosis. Brain asymmetry on imaging studies was noted in 9 (30%) patients. Response to levodopa was rated as good in 18, moderate in 6, and poor in 6. Nine of 19 (47%) patients in whom birth history was available had difficult birth or had severe febrile illness in the first few months of life. Overall 10 (33%) patients had difficulty in walking during early childhood.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Although the clinical features of hemiparkinsonism-hemiatrophy syndrome are variable, suggesting a heterogeneous pathogenesis, perinatal and early childhood cerebral injury appears to play an important role in about half of the cases.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Wijemanne</LastName>
<ForeName>Subhashie</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Suite 1801, 6550 Fannin, Houston, TX 77030, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jankovic</LastName>
<ForeName>Joseph</ForeName>
<Initials>J</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
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<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Neurology</MedlineTA>
<NlmUniqueID>0401060</NlmUniqueID>
<ISSNLinking>0028-3878</ISSNLinking>
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<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000293">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D001284">Atrophy</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000150">complications</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000175">diagnosis</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000503">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D001720">Birth Injuries</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000150">complications</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D001921">Brain</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D001925">Brain Damage, Chronic</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000150">complications</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000209">etiology</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D004421">Dystonia</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000209">etiology</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005121">Extremities</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005150">Facial Hemiatrophy</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000150">complications</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000175">diagnosis</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006130">Growth Disorders</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000150">complications</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000175">diagnosis</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000503">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008279">Magnetic Resonance Imaging</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D018482">Muscle, Skeletal</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D010300">Parkinson Disease</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000150">complications</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000175">diagnosis</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000503">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D012600">Scoliosis</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000209">etiology</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D003294">Seizures, Febrile</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000150">complications</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D013577">Syndrome</DescriptorName>
</MeshHeading>
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