Genomewide association study for onset age in Parkinson disease.
Identifieur interne : 000107 ( PubMed/Corpus ); précédent : 000106; suivant : 000108Genomewide association study for onset age in Parkinson disease.
Auteurs : Jeanne. Latourelle ; Nathan Pankratz ; Alexandra Dumitriu ; Jemma. Wilk ; Stefano Goldwurm ; Gianni Pezzoli ; Claudio. Mariani ; Anita. Destefano ; Cheryl Halter ; James. Gusella ; William. Nichols ; Richard. Myers ; Tatiana ForoudSource :
- BMC medical genetics ; 2009.
English descriptors
- KwdEn :
- MESH :
Abstract
Age at onset in Parkinson disease (PD) is a highly heritable quantitative trait for which a significant genetic influence is supported by multiple segregation analyses. Because genes associated with onset age may represent invaluable therapeutic targets to delay the disease, we sought to identify such genetic modifiers using a genomewide association study in familial PD. There have been previous genomewide association studies (GWAS) to identify genes influencing PD susceptibility, but this is the first to identify genes contributing to the variation in onset age.
DOI: 10.1186/1471-2350-10-98
PubMed: 19772629
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Genomewide association study for onset age in Parkinson disease.</title><author><name sortKey="Latourelle, Jeanne C" sort="Latourelle, Jeanne C" uniqKey="Latourelle J" first="Jeanne" last="Latourelle">Jeanne. Latourelle</name><affiliation><nlm:affiliation>Boston University School of Medicine, Boston, MA, USA. jlatoure@bu.edu</nlm:affiliation></affiliation></author><author><name sortKey="Pankratz, Nathan" sort="Pankratz, Nathan" uniqKey="Pankratz N" first="Nathan" last="Pankratz">Nathan Pankratz</name></author><author><name sortKey="Dumitriu, Alexandra" sort="Dumitriu, Alexandra" uniqKey="Dumitriu A" first="Alexandra" last="Dumitriu">Alexandra Dumitriu</name></author><author><name sortKey="Wilk, Jemma B" sort="Wilk, Jemma B" uniqKey="Wilk J" first="Jemma" last="Wilk">Jemma. Wilk</name></author><author><name sortKey="Goldwurm, Stefano" sort="Goldwurm, Stefano" uniqKey="Goldwurm S" first="Stefano" last="Goldwurm">Stefano Goldwurm</name></author><author><name sortKey="Pezzoli, Gianni" sort="Pezzoli, Gianni" uniqKey="Pezzoli G" first="Gianni" last="Pezzoli">Gianni Pezzoli</name></author><author><name sortKey="Mariani, Claudio B" sort="Mariani, Claudio B" uniqKey="Mariani C" first="Claudio" last="Mariani">Claudio. Mariani</name></author><author><name sortKey="Destefano, Anita L" sort="Destefano, Anita L" uniqKey="Destefano A" first="Anita" last="Destefano">Anita. Destefano</name></author><author><name sortKey="Halter, Cheryl" sort="Halter, Cheryl" uniqKey="Halter C" first="Cheryl" last="Halter">Cheryl Halter</name></author><author><name sortKey="Gusella, James F" sort="Gusella, James F" uniqKey="Gusella J" first="James" last="Gusella">James. Gusella</name></author><author><name sortKey="Nichols, William C" sort="Nichols, William C" uniqKey="Nichols W" first="William" last="Nichols">William. Nichols</name></author><author><name sortKey="Myers, Richard H" sort="Myers, Richard H" uniqKey="Myers R" first="Richard" last="Myers">Richard. Myers</name></author><author><name sortKey="Foroud, Tatiana" sort="Foroud, Tatiana" uniqKey="Foroud T" first="Tatiana" last="Foroud">Tatiana Foroud</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2009">2009</date><idno type="doi">10.1186/1471-2350-10-98</idno><idno type="RBID">pubmed:19772629</idno><idno type="pmid">19772629</idno><idno type="wicri:Area/PubMed/Corpus">000107</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Genomewide association study for onset age in Parkinson disease.</title><author><name sortKey="Latourelle, Jeanne C" sort="Latourelle, Jeanne C" uniqKey="Latourelle J" first="Jeanne" last="Latourelle">Jeanne. Latourelle</name><affiliation><nlm:affiliation>Boston University School of Medicine, Boston, MA, USA. jlatoure@bu.edu</nlm:affiliation></affiliation></author><author><name sortKey="Pankratz, Nathan" sort="Pankratz, Nathan" uniqKey="Pankratz N" first="Nathan" last="Pankratz">Nathan Pankratz</name></author><author><name sortKey="Dumitriu, Alexandra" sort="Dumitriu, Alexandra" uniqKey="Dumitriu A" first="Alexandra" last="Dumitriu">Alexandra Dumitriu</name></author><author><name sortKey="Wilk, Jemma B" sort="Wilk, Jemma B" uniqKey="Wilk J" first="Jemma" last="Wilk">Jemma. Wilk</name></author><author><name sortKey="Goldwurm, Stefano" sort="Goldwurm, Stefano" uniqKey="Goldwurm S" first="Stefano" last="Goldwurm">Stefano Goldwurm</name></author><author><name sortKey="Pezzoli, Gianni" sort="Pezzoli, Gianni" uniqKey="Pezzoli G" first="Gianni" last="Pezzoli">Gianni Pezzoli</name></author><author><name sortKey="Mariani, Claudio B" sort="Mariani, Claudio B" uniqKey="Mariani C" first="Claudio" last="Mariani">Claudio. Mariani</name></author><author><name sortKey="Destefano, Anita L" sort="Destefano, Anita L" uniqKey="Destefano A" first="Anita" last="Destefano">Anita. Destefano</name></author><author><name sortKey="Halter, Cheryl" sort="Halter, Cheryl" uniqKey="Halter C" first="Cheryl" last="Halter">Cheryl Halter</name></author><author><name sortKey="Gusella, James F" sort="Gusella, James F" uniqKey="Gusella J" first="James" last="Gusella">James. Gusella</name></author><author><name sortKey="Nichols, William C" sort="Nichols, William C" uniqKey="Nichols W" first="William" last="Nichols">William. Nichols</name></author><author><name sortKey="Myers, Richard H" sort="Myers, Richard H" uniqKey="Myers R" first="Richard" last="Myers">Richard. Myers</name></author><author><name sortKey="Foroud, Tatiana" sort="Foroud, Tatiana" uniqKey="Foroud T" first="Tatiana" last="Foroud">Tatiana Foroud</name></author></analytic><series><title level="j">BMC medical genetics</title><idno type="e-ISSN">1471-2350</idno><imprint><date when="2009" type="published">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Age of Onset</term><term>Aged</term><term>Aged, 80 and over</term><term>Female</term><term>Genome-Wide Association Study</term><term>Humans</term><term>Linear Models</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (genetics)</term><term>Polymorphism, Single Nucleotide</term><term>Young Adult</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Age of Onset</term><term>Aged</term><term>Aged, 80 and over</term><term>Female</term><term>Genome-Wide Association Study</term><term>Humans</term><term>Linear Models</term><term>Male</term><term>Middle Aged</term><term>Polymorphism, Single Nucleotide</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Age at onset in Parkinson disease (PD) is a highly heritable quantitative trait for which a significant genetic influence is supported by multiple segregation analyses. Because genes associated with onset age may represent invaluable therapeutic targets to delay the disease, we sought to identify such genetic modifiers using a genomewide association study in familial PD. There have been previous genomewide association studies (GWAS) to identify genes influencing PD susceptibility, but this is the first to identify genes contributing to the variation in onset age.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">19772629</PMID><DateCreated><Year>2009</Year><Month>10</Month><Day>07</Day></DateCreated><DateCompleted><Year>2009</Year><Month>10</Month><Day>07</Day></DateCompleted><DateRevised><Year>2014</Year><Month>12</Month><Day>07</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1471-2350</ISSN><JournalIssue CitedMedium="Internet"><Volume>10</Volume><PubDate><Year>2009</Year></PubDate></JournalIssue><Title>BMC medical genetics</Title><ISOAbbreviation>BMC Med. Genet.</ISOAbbreviation></Journal><ArticleTitle>Genomewide association study for onset age in Parkinson disease.</ArticleTitle><Pagination><MedlinePgn>98</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1186/1471-2350-10-98</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Age at onset in Parkinson disease (PD) is a highly heritable quantitative trait for which a significant genetic influence is supported by multiple segregation analyses. Because genes associated with onset age may represent invaluable therapeutic targets to delay the disease, we sought to identify such genetic modifiers using a genomewide association study in familial PD. There have been previous genomewide association studies (GWAS) to identify genes influencing PD susceptibility, but this is the first to identify genes contributing to the variation in onset age.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Initial analyses were performed using genotypes generated with the Illumina HumanCNV370Duo array in a sample of 857 unrelated, familial PD cases. Subsequently, a meta-analysis of imputed SNPs was performed combining the familial PD data with that from a previous GWAS of 440 idiopathic PD cases. The SNPs from the meta-analysis with the lowest p-values and consistency in the direction of effect for onset age were then genotyped in a replication sample of 747 idiopathic PD cases from the Parkinson Institute Biobank of Milan, Italy.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Meta-analysis across the three studies detected consistent association (p < 1 x 10(-5)) with five SNPs, none of which reached genomewide significance. On chromosome 11, the SNP with the lowest p-value (rs10767971; p = 5.4 x 10(-7)) lies between the genes QSER1 and PRRG4. Near the PARK3 linkage region on chromosome 2p13, association was observed with a SNP (rs7577851; p = 8.7 x 10(-6)) which lies in an intron of the AAK1 gene. This gene is closely related to GAK, identified as a possible PD susceptibility gene in the GWAS of the familial PD cases.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Taken together, these results suggest an influence of genes involved in endocytosis and lysosomal sorting in PD pathogenesis.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Latourelle</LastName><ForeName>Jeanne C</ForeName><Initials>JC</Initials><AffiliationInfo><Affiliation>Boston University School of Medicine, Boston, MA, USA. jlatoure@bu.edu</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pankratz</LastName><ForeName>Nathan</ForeName><Initials>N</Initials></Author><Author ValidYN="Y"><LastName>Dumitriu</LastName><ForeName>Alexandra</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Wilk</LastName><ForeName>Jemma B</ForeName><Initials>JB</Initials></Author><Author ValidYN="Y"><LastName>Goldwurm</LastName><ForeName>Stefano</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Pezzoli</LastName><ForeName>Gianni</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Mariani</LastName><ForeName>Claudio B</ForeName><Initials>CB</Initials></Author><Author ValidYN="Y"><LastName>DeStefano</LastName><ForeName>Anita L</ForeName><Initials>AL</Initials></Author><Author ValidYN="Y"><LastName>Halter</LastName><ForeName>Cheryl</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Gusella</LastName><ForeName>James F</ForeName><Initials>JF</Initials></Author><Author ValidYN="Y"><LastName>Nichols</LastName><ForeName>William C</ForeName><Initials>WC</Initials></Author><Author ValidYN="Y"><LastName>Myers</LastName><ForeName>Richard H</ForeName><Initials>RH</Initials></Author><Author ValidYN="Y"><LastName>Foroud</LastName><ForeName>Tatiana</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><CollectiveName>PROGENI Investigators, Coordinators and Molecular Genetic Laboratories</CollectiveName></Author><Author ValidYN="Y"><CollectiveName>GenePD Investigators, Coordinators and Molecular Genetic Laboratories</CollectiveName></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>GTB07001</GrantID><Agency>Telethon</Agency><Country>Italy</Country></Grant><Grant><GrantID>HHSN268200782096C</GrantID><Agency>PHS HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 NS036711</GrantID><Acronym>NS</Acronym><Agency>NINDS NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 NS036711</GrantID><Acronym>NS</Acronym><Agency>NINDS NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 NS036711-09</GrantID><Acronym>NS</Acronym><Agency>NINDS NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 NS37167</GrantID><Acronym>NS</Acronym><Agency>NINDS NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D017418">Meta-Analysis</PublicationType><PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D013487">Research Support, U.S. Gov't, P.H.S.</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2009</Year><Month>09</Month><Day>22</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>BMC Med Genet</MedlineTA><NlmUniqueID>100968552</NlmUniqueID><ISSNLinking>1471-2350</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Parkinsonism Relat Disord. 2008;14(5):426-30</RefSource><PMID Version="1">18325820</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Biochemistry. 2008 Sep 9;47(36):9678-87</RefSource><PMID Version="1">18702517</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Hum Mol Genet. 2008 Oct 15;17(R2):R122-8</RefSource><PMID Version="1">18852200</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>BMC Med. 2008;6:32</RefSource><PMID Version="1">18986508</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Hum Genet. 2009 Jan;124(6):593-605</RefSource><PMID Version="1">18985386</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Med Hypotheses. 2009 Mar;72(3):280-4</RefSource><PMID Version="1">19027242</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neurosci. 2002 Dec 15;22(24):10690-8</RefSource><PMID Version="1">12486162</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2003 Mar;18(3):275-9</RefSource><PMID Version="1">12621630</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2003 Mar 11;60(5):796-801</RefSource><PMID Version="1">12629236</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2009 Jun 15;24(8):1125-31</RefSource><PMID Version="1">19412953</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Hum Genet. 2001 Apr;68(4):895-900</RefSource><PMID Version="1">11254447</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Hum Genet. 2001 Sep;69(3):629-34</RefSource><PMID Version="1">11462174</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Gene. 2001 Oct 17;277(1-2):49-62</RefSource><PMID Version="1">11602344</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2002 Jan 8;58(1):79-84</RefSource><PMID Version="1">11781409</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Hum Genet. 2002 Apr;70(4):985-93</RefSource><PMID Version="1">11875758</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Hum Genet. 2002 May;70(5):1089-95</RefSource><PMID Version="1">11920285</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Med Genet. 2002 May 1;109(3):191-7</RefSource><PMID Version="1">11977177</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Hum Genet. 2002 Jul;71(1):124-35</RefSource><PMID Version="1">12058349</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cancer Epidemiol Biomarkers Prev. 2002 Aug;11(8):782-4</RefSource><PMID Version="1">12163334</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Annu Rev Neurosci. 2003;26:81-104</RefSource><PMID Version="1">12574495</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nature. 2003 Dec 18;426(6968):789-96</RefSource><PMID Version="1">14685227</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3498-503</RefSource><PMID Version="1">14993615</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2004 May 11;62(9):1616-8</RefSource><PMID Version="1">15136695</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Twin Res. 2004 Apr;7(2):197-210</RefSource><PMID Version="1">15169604</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurogenetics. 2004 Jun;5(2):109-14</RefSource><PMID Version="1">15029481</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2004 Jun;19(6):649-55</RefSource><PMID Version="1">15197702</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neurol Neurosurg Psychiatry. 1988 Jun;51(6):745-52</RefSource><PMID Version="1">2841426</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>N Engl J Med. 1994 Feb 24;330(8):529-34</RefSource><PMID Version="1">8302318</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Science. 1996 Sep 13;273(5281):1516-7</RefSource><PMID Version="1">8801636</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Science. 1997 Jun 27;276(5321):2045-7</RefSource><PMID Version="1">9197268</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nature. 1998 Apr 9;392(6676):605-8</RefSource><PMID Version="1">9560156</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Neurol. 1998 Sep;44(3 Suppl 1):S53-7</RefSource><PMID Version="1">9749573</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 1998 Nov;13(6):885-94</RefSource><PMID Version="1">9827611</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Med Genet. 1998 Dec 4;80(4):410-7</RefSource><PMID Version="1">9856574</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 1999 Apr 12;52(6):1214-20</RefSource><PMID Version="1">10214746</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Curr Opin Cell Biol. 2004 Dec;16(6):653-62</RefSource><PMID Version="1">15530777</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neuron. 2004 Nov 18;44(4):595-600</RefSource><PMID Version="1">15541308</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 2005 Jan 29-Feb 4;365(9457):410-2</RefSource><PMID Version="1">15680455</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Br J Cancer. 2005 Jan 17;92(1):201-5</RefSource><PMID Version="1">15583688</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Prog Neurobiol. 2005 Feb;75(2):109-24</RefSource><PMID Version="1">15784302</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Med Genet B Neuropsychiatr Genet. 2005 Aug 5;137B(1):5-16</RefSource><PMID Version="1">15965975</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2005 Sep;20(9):1188-91</RefSource><PMID Version="1">15966003</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur J Hum Genet. 2005 Aug;13(8):913-20</RefSource><PMID Version="1">15889046</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Hum Genet. 2005 Nov;77(5):685-93</RefSource><PMID Version="1">16252231</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cancer Biol Ther. 2005 Sep;4(9):1018-29</RefSource><PMID Version="1">16251803</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Death Differ. 2006 Mar;13(3):385-92</RefSource><PMID Version="1">16397584</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Neurol. 2006 May;59(5):788-95</RefSource><PMID Version="1">16634030</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Arch Neurol. 2006 Jun;63(6):826-32</RefSource><PMID Version="1">16769863</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Science. 2006 Jul 21;313(5785):324-8</RefSource><PMID Version="1">16794039</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Epidemiology. 2006 Sep;17(5):582-7</RefSource><PMID Version="1">16837822</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Methods Enzymol. 2006;410:359-76</RefSource><PMID Version="1">16938560</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Physiol Rev. 2006 Oct;86(4):1133-49</RefSource><PMID Version="1">17015486</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet Neurol. 2006 Nov;5(11):911-6</RefSource><PMID Version="1">17052657</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2006 Dec;21(12):2257-60</RefSource><PMID Version="1">17078063</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Med Genet. 2007 Jan;44(1):44-50</RefSource><PMID Version="1">17018562</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Hum Genet. 2007 Feb;80(2):241-52</RefSource><PMID Version="1">17236130</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Biochem Biophys Res Commun. 2007 Mar 16;354(3):707-11</RefSource><PMID Version="1">17254549</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2007 Apr 3;68(14):1141-3</RefSource><PMID Version="1">17215492</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Genet Epidemiol. 2007 May;31(4):358-62</RefSource><PMID Version="1">17352422</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cancer Epidemiol Biomarkers Prev. 2007 Jun;16(6):1260-5</RefSource><PMID Version="1">17548694</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nature. 2007 Jun 7;447(7145):661-78</RefSource><PMID Version="1">17554300</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Genet. 2007 Jul;39(7):906-13</RefSource><PMID Version="1">17572673</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Biol Cell. 2007 Jul;18(7):2698-706</RefSource><PMID Version="1">17494869</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Biol Cell. 2007 Aug;18(8):2991-3001</RefSource><PMID Version="1">17538018</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Hum Genet. 2007 Sep;81(3):559-75</RefSource><PMID Version="1">17701901</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Obesity (Silver Spring). 2007 Aug;15(8):2061-70</RefSource><PMID Version="1">17712124</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Hum Genet. 2007 Nov;122(3-4):311-26</RefSource><PMID Version="1">17619204</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2007 Oct 30;69(18):1737-44</RefSource><PMID Version="1">17804834</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Genet. 2007 Dec;39(12):1443-52</RefSource><PMID Version="1">17952075</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Genet. 2008 Feb;40(2):161-9</RefSource><PMID Version="1">18193043</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Genet. 2008 Feb;40(2):198-203</RefSource><PMID Version="1">18193045</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Genet Epidemiol. 2008 Apr;32(3):227-34</RefSource><PMID Version="1">18300295</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Genet Epidemiol. 2008 May;32(4):381-5</RefSource><PMID Version="1">18348202</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Biol Psychiatry. 2008 Jun 15;63(12):1185-9</RefSource><PMID Version="1">18367154</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D017668">Age of Onset</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000369">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D055106">Genome-Wide Association 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