JankovicV1, PubMed, Corpus, bibRecord, 000032

Parkinson disease subtypes.

Identifieur interne : 000032 ( PubMed/Corpus ); précédent : 000031; suivant : 000033

Parkinson disease subtypes.

Auteurs : Mary Thenganatt ; Joseph Jankovic

Source :

JAMA neurology ; 2014.

RBID : pubmed:24514863

English descriptors

KwdEn :
- Biomarkers (chemistry), Humans, Movement Disorders (classification), Movement Disorders (diagnosis), Movement Disorders (genetics), Parkinson Disease (classification), Parkinson Disease (diagnosis), Parkinson Disease (genetics), Tremor (classification), Tremor (diagnosis), Tremor (genetics).
MESH :
- chemical , chemistry : Biomarkers.
- classification : Movement Disorders, Parkinson Disease, Tremor.
- diagnosis : Movement Disorders, Parkinson Disease, Tremor.
- genetics : Movement Disorders, Parkinson Disease, Tremor.
- Humans.

Abstract

It is increasingly evident that Parkinson disease (PD) is not a single entity but rather a heterogeneous neurodegenerative disorder.

DOI: 10.1001/jamaneurol.2013.6233
PubMed: 24514863

Links to Exploration step

pubmed:24514863

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Parkinson disease subtypes.</title>
<author><name sortKey="Thenganatt, Mary Ann" sort="Thenganatt, Mary Ann" uniqKey="Thenganatt M" first="Mary" last="Thenganatt">Mary Thenganatt</name>
<affiliation><nlm:affiliation>Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name>
<affiliation><nlm:affiliation>Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas.</nlm:affiliation>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2014">2014</date>
<idno type="doi">10.1001/jamaneurol.2013.6233</idno>
<idno type="RBID">pubmed:24514863</idno>
<idno type="pmid">24514863</idno>
<idno type="wicri:Area/PubMed/Corpus">000032</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Parkinson disease subtypes.</title>
<author><name sortKey="Thenganatt, Mary Ann" sort="Thenganatt, Mary Ann" uniqKey="Thenganatt M" first="Mary" last="Thenganatt">Mary Thenganatt</name>
<affiliation><nlm:affiliation>Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name>
<affiliation><nlm:affiliation>Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas.</nlm:affiliation>
</affiliation>
</author>
</analytic>
<series><title level="j">JAMA neurology</title>
<idno type="e-ISSN">2168-6157</idno>
<imprint><date when="2014" type="published">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Biomarkers (chemistry)</term>
<term>Humans</term>
<term>Movement Disorders (classification)</term>
<term>Movement Disorders (diagnosis)</term>
<term>Movement Disorders (genetics)</term>
<term>Parkinson Disease (classification)</term>
<term>Parkinson Disease (diagnosis)</term>
<term>Parkinson Disease (genetics)</term>
<term>Tremor (classification)</term>
<term>Tremor (diagnosis)</term>
<term>Tremor (genetics)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Biomarkers</term>
</keywords>
<keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Movement Disorders</term>
<term>Parkinson Disease</term>
<term>Tremor</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Movement Disorders</term>
<term>Parkinson Disease</term>
<term>Tremor</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Movement Disorders</term>
<term>Parkinson Disease</term>
<term>Tremor</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Humans</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">It is increasingly evident that Parkinson disease (PD) is not a single entity but rather a heterogeneous neurodegenerative disorder.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">24514863</PMID>
<DateCreated><Year>2014</Year>
<Month>04</Month>
<Day>15</Day>
</DateCreated>
<DateCompleted><Year>2014</Year>
<Month>06</Month>
<Day>09</Day>
</DateCompleted>
<DateRevised><Year>2015</Year>
<Month>11</Month>
<Day>19</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">2168-6157</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>71</Volume>
<Issue>4</Issue>
<PubDate><Year>2014</Year>
<Month>Apr</Month>
</PubDate>
</JournalIssue>
<Title>JAMA neurology</Title>
<ISOAbbreviation>JAMA Neurol</ISOAbbreviation>
</Journal>
<ArticleTitle>Parkinson disease subtypes.</ArticleTitle>
<Pagination><MedlinePgn>499-504</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1001/jamaneurol.2013.6233</ELocationID>
<Abstract><AbstractText Label="IMPORTANCE" NlmCategory="OBJECTIVE">It is increasingly evident that Parkinson disease (PD) is not a single entity but rather a heterogeneous neurodegenerative disorder.</AbstractText>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To evaluate available evidence, based on findings from clinical, imaging, genetic and pathologic studies, supporting the differentiation of PD into subtypes.</AbstractText>
<AbstractText Label="EVIDENCE REVIEW" NlmCategory="METHODS">We performed a systematic review of articles cited in PubMed between 1980 and 2013 using the following search terms: Parkinson disease, parkinsonism, tremor, postural instability and gait difficulty, and Parkinson disease subtypes. The final reference list was generated on the basis of originality and relevance to the broad scope of this review.</AbstractText>
<AbstractText Label="FINDINGS" NlmCategory="RESULTS">Several subtypes, such as tremor-dominant PD and postural instability gait difficulty form of PD, have been found to cluster together. Other subtypes also have been identified, but validation by subtype-specific biomarkers is still lacking.</AbstractText>
<AbstractText Label="CONCLUSIONS AND RELEVANCE" NlmCategory="CONCLUSIONS">Several PD subtypes have been identified, but the pathogenic mechanisms underlying the observed clinicopathologic heterogeneity in PD are still not well understood. Further research into subtype-specific diagnostic and prognostic biomarkers may provide insights into mechanisms of neurodegeneration and improve epidemiologic and therapeutic clinical trial designs.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Thenganatt</LastName>
<ForeName>Mary Ann</ForeName>
<Initials>MA</Initials>
<AffiliationInfo><Affiliation>Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jankovic</LastName>
<ForeName>Joseph</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D016454">Review</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>JAMA Neurol</MedlineTA>
<NlmUniqueID>101589536</NlmUniqueID>
<ISSNLinking>2168-6149</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D015415">Biomarkers</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>AIM</CitationSubset>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D015415">Biomarkers</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000737">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D009069">Movement Disorders</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000145">classification</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000175">diagnosis</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D010300">Parkinson Disease</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000145">classification</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000175">diagnosis</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D014202">Tremor</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000145">classification</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000175">diagnosis</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2014</Year>
<Month>2</Month>
<Day>12</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2014</Year>
<Month>2</Month>
<Day>12</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2014</Year>
<Month>6</Month>
<Day>10</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pii">1827554</ArticleId>
<ArticleId IdType="doi">10.1001/jamaneurol.2013.6233</ArticleId>
<ArticleId IdType="pubmed">24514863</ArticleId>
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</record>

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Serveur d'exploration autour de Joseph Jankovic

Parkinson disease subtypes.

Parkinson disease subtypes.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki