Role of the H1 haplotype of microtubule-associated protein tau (MAPT) gene in Greek patients with Parkinson's disease
Identifieur interne : 000107 ( Pmc/Corpus ); précédent : 000106; suivant : 000108Role of the H1 haplotype of microtubule-associated protein tau (MAPT) gene in Greek patients with Parkinson's disease
Auteurs : Nikolaos Refenes ; Juliane Bolbrinker ; Georgios Tagaris ; Antonio Orlacchio ; Nikolaos Drakoulis ; Reinhold KreutzSource :
- BMC Neurology ; 2009.
Abstract
The extended tau haplotype (H1) that covers the entire human microtubule-associated protein tau (
We analysed
The presence of the H1 haplotype was significantly associated with PD (odds ratio for H1H1 vs. H1H2 and H2H2: 1.566; 95% CI: 1.137–2.157;
Our data support the overall genetic role of
Url:
DOI: 10.1186/1471-2377-9-26
PubMed: 19558713
PubMed Central: 2709887
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