Stem cell transplantation therapy in Parkinson’s disease
Identifieur interne : 000039 ( Pmc/Corpus ); précédent : 000038; suivant : 000040Stem cell transplantation therapy in Parkinson’s disease
Auteurs : Mu Fu ; Chia Li ; Hsiu Lin ; Pei Chen ; Marcus Calkins ; Yu Chang ; Pei Cheng ; Shang YangSource :
- SpringerPlus ; 2015.
Abstract
Ineffective therapeutic treatments and inadequate repair ability in the central nervous system are disturbing problems for several neurological diseases. Fortunately, the development of clinically applicable populations of stem cells has provided an avenue to overcome the failure of endogenous repair systems and substitute new cells into the damaged brain. However, there are still several existing obstacles to translating into clinical application. Here we review the stem-cell based therapies for Parkinson’s disease and discuss the potential advantages and drawbacks. We hope this review may provide suggestions for viable strategies to overcome the current technical and biological issues associated with the application of stem cells in Parkinson’s disease.
Url:
DOI: 10.1186/s40064-015-1400-1
PubMed: 26543732
PubMed Central: 4628010
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