Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial.
Identifieur interne : 000075 ( Ncbi/Merge ); précédent : 000074; suivant : 000076Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial.
Auteurs : Robert. Holloway [États-Unis] ; Ira Shoulson ; Stanley Fahn ; Karl Kieburtz ; Anthony Lang ; Kenneth Marek ; Michael Mcdermott ; John Seibyl ; William Weiner ; Bruno Musch ; Cornelia Kamp ; Mickie Welsh ; Aileen Shinaman ; Rajesh Pahwa ; Lynn Barclay ; Jean Hubble ; Peter Lewitt ; Janis Miyasaki ; Oksana Suchowersky ; Mark Stacy ; David. Russell ; Blair Ford ; John Hammerstad ; David Riley ; David Standaert ; Frederick Wooten ; Stewart Factor ; Joseph Jankovic [États-Unis] ; Farah Atassi ; Roger Kurlan ; Michel Panisset ; Ali Rajput ; Robert Rodnitzky ; Cliff Shults ; Giselle Petsinger ; Cheryl Waters ; Ronald Pfeiffer ; Kevin Biglan ; Leona Borchert ; Amy Montgomery ; Laura Sutherland ; Carolyn Weeks ; Maryan Deangelis ; Elspeth Sime ; Susan Wood ; Carol Pantella ; Mary Harrigan ; Barbara Fussell ; Sandra Dillon ; Barbara Alexander ; Pamela Rainey ; Marsha Tennis ; Elke Rost ; Diane Brown ; Sharon Evans ; Debra Berry ; Jean Hall ; Theresa Shirley ; Judith Dobson ; Deborah Fontaine ; Brenda Pfeiffer ; Alicia Brocht ; Susan Bennett ; Susan Daigneault ; Karen Hodgeman ; Carolynn O ; Tori Ross ; Karen Richard ; Arthur WattsSource :
- Archives of neurology [ 0003-9942 ] ; 2004.
English descriptors
- KwdEn :
- Aged, Benzothiazoles, Double-Blind Method, Female, Follow-Up Studies, Humans, Levodopa (adverse effects), Levodopa (therapeutic use), Male, Middle Aged, Parkinson Disease (drug therapy), Parkinson Disease (physiopathology), Parkinson Disease (psychology), Proportional Hazards Models, Quality of Life (psychology), Severity of Illness Index, Thiazoles (adverse effects), Thiazoles (therapeutic use).
- MESH :
- chemical , adverse effects : Levodopa, Thiazoles.
- chemical , therapeutic use : Levodopa, Thiazoles.
- chemical : Benzothiazoles.
- drug therapy : Parkinson Disease.
- physiopathology : Parkinson Disease.
- psychology : Parkinson Disease, Quality of Life.
- Aged, Double-Blind Method, Female, Follow-Up Studies, Humans, Male, Middle Aged, Proportional Hazards Models, Severity of Illness Index.
Abstract
The best way to initiate dopaminergic therapy for early Parkinson disease remains unclear.
DOI: 10.1001/archneur.61.7.1044
PubMed: 15262734
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000207
- to stream PubMed, to step Curation: 000207
- to stream PubMed, to step Checkpoint: 000204
Links to Exploration step
pubmed:15262734Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial.</title><author><name sortKey="Holloway, Robert G" sort="Holloway, Robert G" uniqKey="Holloway R" first="Robert" last="Holloway">Robert. Holloway</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, University of Rochester, 1351 Mt. Hope Avenue, Suite 220, Rochester, NY 14620, USA. robert.holloway@ctcc.rochester.edu</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of Rochester, 1351 Mt. Hope Avenue, Suite 220, Rochester, NY 14620</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Shoulson, Ira" sort="Shoulson, Ira" uniqKey="Shoulson I" first="Ira" last="Shoulson">Ira Shoulson</name></author><author><name sortKey="Fahn, Stanley" sort="Fahn, Stanley" uniqKey="Fahn S" first="Stanley" last="Fahn">Stanley Fahn</name></author><author><name sortKey="Kieburtz, Karl" sort="Kieburtz, Karl" uniqKey="Kieburtz K" first="Karl" last="Kieburtz">Karl Kieburtz</name></author><author><name sortKey="Lang, Anthony" sort="Lang, Anthony" uniqKey="Lang A" first="Anthony" last="Lang">Anthony Lang</name></author><author><name sortKey="Marek, Kenneth" sort="Marek, Kenneth" uniqKey="Marek K" first="Kenneth" last="Marek">Kenneth Marek</name></author><author><name sortKey="Mcdermott, Michael" sort="Mcdermott, Michael" uniqKey="Mcdermott M" first="Michael" last="Mcdermott">Michael Mcdermott</name></author><author><name sortKey="Seibyl, John" sort="Seibyl, John" uniqKey="Seibyl J" first="John" last="Seibyl">John Seibyl</name></author><author><name sortKey="Weiner, William" sort="Weiner, William" uniqKey="Weiner W" first="William" last="Weiner">William Weiner</name></author><author><name sortKey="Musch, Bruno" sort="Musch, Bruno" uniqKey="Musch B" first="Bruno" last="Musch">Bruno Musch</name></author><author><name sortKey="Kamp, Cornelia" sort="Kamp, Cornelia" uniqKey="Kamp C" first="Cornelia" last="Kamp">Cornelia Kamp</name></author><author><name sortKey="Welsh, Mickie" sort="Welsh, Mickie" uniqKey="Welsh M" first="Mickie" last="Welsh">Mickie Welsh</name></author><author><name sortKey="Shinaman, Aileen" sort="Shinaman, Aileen" uniqKey="Shinaman A" first="Aileen" last="Shinaman">Aileen Shinaman</name></author><author><name sortKey="Pahwa, Rajesh" sort="Pahwa, Rajesh" uniqKey="Pahwa R" first="Rajesh" last="Pahwa">Rajesh Pahwa</name></author><author><name sortKey="Barclay, Lynn" sort="Barclay, Lynn" uniqKey="Barclay L" first="Lynn" last="Barclay">Lynn Barclay</name></author><author><name sortKey="Hubble, Jean" sort="Hubble, Jean" uniqKey="Hubble J" first="Jean" last="Hubble">Jean Hubble</name></author><author><name sortKey="Lewitt, Peter" sort="Lewitt, Peter" uniqKey="Lewitt P" first="Peter" last="Lewitt">Peter Lewitt</name></author><author><name sortKey="Miyasaki, Janis" sort="Miyasaki, Janis" uniqKey="Miyasaki J" first="Janis" last="Miyasaki">Janis Miyasaki</name></author><author><name sortKey="Suchowersky, Oksana" sort="Suchowersky, Oksana" uniqKey="Suchowersky O" first="Oksana" last="Suchowersky">Oksana Suchowersky</name></author><author><name sortKey="Stacy, Mark" sort="Stacy, Mark" uniqKey="Stacy M" first="Mark" last="Stacy">Mark Stacy</name></author><author><name sortKey="Russell, David S" sort="Russell, David S" uniqKey="Russell D" first="David" last="Russell">David. Russell</name></author><author><name sortKey="Ford, Blair" sort="Ford, Blair" uniqKey="Ford B" first="Blair" last="Ford">Blair Ford</name></author><author><name sortKey="Hammerstad, John" sort="Hammerstad, John" uniqKey="Hammerstad J" first="John" last="Hammerstad">John Hammerstad</name></author><author><name sortKey="Riley, David" sort="Riley, David" uniqKey="Riley D" first="David" last="Riley">David Riley</name></author><author><name sortKey="Standaert, David" sort="Standaert, David" uniqKey="Standaert D" first="David" last="Standaert">David Standaert</name></author><author><name sortKey="Wooten, Frederick" sort="Wooten, Frederick" uniqKey="Wooten F" first="Frederick" last="Wooten">Frederick Wooten</name></author><author><name sortKey="Factor, Stewart" sort="Factor, Stewart" uniqKey="Factor S" first="Stewart" last="Factor">Stewart Factor</name></author><author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name><affiliation><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName><orgName type="university" n="3">Baylor College of Medicine</orgName></affiliation></author><author><name sortKey="Atassi, Farah" sort="Atassi, Farah" uniqKey="Atassi F" first="Farah" last="Atassi">Farah Atassi</name></author><author><name sortKey="Kurlan, Roger" sort="Kurlan, Roger" uniqKey="Kurlan R" first="Roger" last="Kurlan">Roger Kurlan</name></author><author><name sortKey="Panisset, Michel" sort="Panisset, Michel" uniqKey="Panisset M" first="Michel" last="Panisset">Michel Panisset</name></author><author><name sortKey="Rajput, Ali" sort="Rajput, Ali" uniqKey="Rajput A" first="Ali" last="Rajput">Ali Rajput</name></author><author><name sortKey="Rodnitzky, Robert" sort="Rodnitzky, Robert" uniqKey="Rodnitzky R" first="Robert" last="Rodnitzky">Robert Rodnitzky</name></author><author><name sortKey="Shults, Cliff" sort="Shults, Cliff" uniqKey="Shults C" first="Cliff" last="Shults">Cliff Shults</name></author><author><name sortKey="Petsinger, Giselle" sort="Petsinger, Giselle" uniqKey="Petsinger G" first="Giselle" last="Petsinger">Giselle Petsinger</name></author><author><name sortKey="Waters, Cheryl" sort="Waters, Cheryl" uniqKey="Waters C" first="Cheryl" last="Waters">Cheryl Waters</name></author><author><name sortKey="Pfeiffer, Ronald" sort="Pfeiffer, Ronald" uniqKey="Pfeiffer R" first="Ronald" last="Pfeiffer">Ronald Pfeiffer</name></author><author><name sortKey="Biglan, Kevin" sort="Biglan, Kevin" uniqKey="Biglan K" first="Kevin" last="Biglan">Kevin Biglan</name></author><author><name sortKey="Borchert, Leona" sort="Borchert, Leona" uniqKey="Borchert L" first="Leona" last="Borchert">Leona Borchert</name></author><author><name sortKey="Montgomery, Amy" sort="Montgomery, Amy" uniqKey="Montgomery A" first="Amy" last="Montgomery">Amy Montgomery</name></author><author><name sortKey="Sutherland, Laura" sort="Sutherland, Laura" uniqKey="Sutherland L" first="Laura" last="Sutherland">Laura Sutherland</name></author><author><name sortKey="Weeks, Carolyn" sort="Weeks, Carolyn" uniqKey="Weeks C" first="Carolyn" last="Weeks">Carolyn Weeks</name></author><author><name sortKey="Deangelis, Maryan" sort="Deangelis, Maryan" uniqKey="Deangelis M" first="Maryan" last="Deangelis">Maryan Deangelis</name></author><author><name sortKey="Sime, Elspeth" sort="Sime, Elspeth" uniqKey="Sime E" first="Elspeth" last="Sime">Elspeth Sime</name></author><author><name sortKey="Wood, Susan" sort="Wood, Susan" uniqKey="Wood S" first="Susan" last="Wood">Susan Wood</name></author><author><name sortKey="Pantella, Carol" sort="Pantella, Carol" uniqKey="Pantella C" first="Carol" last="Pantella">Carol Pantella</name></author><author><name sortKey="Harrigan, Mary" sort="Harrigan, Mary" uniqKey="Harrigan M" first="Mary" last="Harrigan">Mary Harrigan</name></author><author><name sortKey="Fussell, Barbara" sort="Fussell, Barbara" uniqKey="Fussell B" first="Barbara" last="Fussell">Barbara Fussell</name></author><author><name sortKey="Dillon, Sandra" sort="Dillon, Sandra" uniqKey="Dillon S" first="Sandra" last="Dillon">Sandra Dillon</name></author><author><name sortKey="Alexander Brown, Barbara" sort="Alexander Brown, Barbara" uniqKey="Alexander Brown B" first="Barbara" last="Alexander">Barbara Alexander</name></author><author><name sortKey="Rainey, Pamela" sort="Rainey, Pamela" uniqKey="Rainey P" first="Pamela" last="Rainey">Pamela Rainey</name></author><author><name sortKey="Tennis, Marsha" sort="Tennis, Marsha" uniqKey="Tennis M" first="Marsha" last="Tennis">Marsha Tennis</name></author><author><name sortKey="Rost Ruffner, Elke" sort="Rost Ruffner, Elke" uniqKey="Rost Ruffner E" first="Elke" last="Rost">Elke Rost</name></author><author><name sortKey="Brown, Diane" sort="Brown, Diane" uniqKey="Brown D" first="Diane" last="Brown">Diane Brown</name></author><author><name sortKey="Evans, Sharon" sort="Evans, Sharon" uniqKey="Evans S" first="Sharon" last="Evans">Sharon Evans</name></author><author><name sortKey="Berry, Debra" sort="Berry, Debra" uniqKey="Berry D" first="Debra" last="Berry">Debra Berry</name></author><author><name sortKey="Hall, Jean" sort="Hall, Jean" uniqKey="Hall J" first="Jean" last="Hall">Jean Hall</name></author><author><name sortKey="Shirley, Theresa" sort="Shirley, Theresa" uniqKey="Shirley T" first="Theresa" last="Shirley">Theresa Shirley</name></author><author><name sortKey="Dobson, Judith" sort="Dobson, Judith" uniqKey="Dobson J" first="Judith" last="Dobson">Judith Dobson</name></author><author><name sortKey="Fontaine, Deborah" sort="Fontaine, Deborah" uniqKey="Fontaine D" first="Deborah" last="Fontaine">Deborah Fontaine</name></author><author><name sortKey="Pfeiffer, Brenda" sort="Pfeiffer, Brenda" uniqKey="Pfeiffer B" first="Brenda" last="Pfeiffer">Brenda Pfeiffer</name></author><author><name sortKey="Brocht, Alicia" sort="Brocht, Alicia" uniqKey="Brocht A" first="Alicia" last="Brocht">Alicia Brocht</name></author><author><name sortKey="Bennett, Susan" sort="Bennett, Susan" uniqKey="Bennett S" first="Susan" last="Bennett">Susan Bennett</name></author><author><name sortKey="Daigneault, Susan" sort="Daigneault, Susan" uniqKey="Daigneault S" first="Susan" last="Daigneault">Susan Daigneault</name></author><author><name sortKey="Hodgeman, Karen" sort="Hodgeman, Karen" uniqKey="Hodgeman K" first="Karen" last="Hodgeman">Karen Hodgeman</name></author><author><name sortKey="O Connell, Carolynn" sort="O Connell, Carolynn" uniqKey="O Connell C" first="Carolynn" last="O">Carolynn O</name></author><author><name sortKey="Ross, Tori" sort="Ross, Tori" uniqKey="Ross T" first="Tori" last="Ross">Tori Ross</name></author><author><name sortKey="Richard, Karen" sort="Richard, Karen" uniqKey="Richard K" first="Karen" last="Richard">Karen Richard</name></author><author><name sortKey="Watts, Arthur" sort="Watts, Arthur" uniqKey="Watts A" first="Arthur" last="Watts">Arthur Watts</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2004">2004</date><idno type="RBID">pubmed:15262734</idno><idno type="pmid">15262734</idno><idno type="doi">10.1001/archneur.61.7.1044</idno><idno type="wicri:Area/PubMed/Corpus">000207</idno><idno type="wicri:Area/PubMed/Curation">000207</idno><idno type="wicri:Area/PubMed/Checkpoint">000204</idno><idno type="wicri:Area/Ncbi/Merge">000075</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial.</title><author><name sortKey="Holloway, Robert G" sort="Holloway, Robert G" uniqKey="Holloway R" first="Robert" last="Holloway">Robert. Holloway</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, University of Rochester, 1351 Mt. Hope Avenue, Suite 220, Rochester, NY 14620, USA. robert.holloway@ctcc.rochester.edu</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of Rochester, 1351 Mt. Hope Avenue, Suite 220, Rochester, NY 14620</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Shoulson, Ira" sort="Shoulson, Ira" uniqKey="Shoulson I" first="Ira" last="Shoulson">Ira Shoulson</name></author><author><name sortKey="Fahn, Stanley" sort="Fahn, Stanley" uniqKey="Fahn S" first="Stanley" last="Fahn">Stanley Fahn</name></author><author><name sortKey="Kieburtz, Karl" sort="Kieburtz, Karl" uniqKey="Kieburtz K" first="Karl" last="Kieburtz">Karl Kieburtz</name></author><author><name sortKey="Lang, Anthony" sort="Lang, Anthony" uniqKey="Lang A" first="Anthony" last="Lang">Anthony Lang</name></author><author><name sortKey="Marek, Kenneth" sort="Marek, Kenneth" uniqKey="Marek K" first="Kenneth" last="Marek">Kenneth Marek</name></author><author><name sortKey="Mcdermott, Michael" sort="Mcdermott, Michael" uniqKey="Mcdermott M" first="Michael" last="Mcdermott">Michael Mcdermott</name></author><author><name sortKey="Seibyl, John" sort="Seibyl, John" uniqKey="Seibyl J" first="John" last="Seibyl">John Seibyl</name></author><author><name sortKey="Weiner, William" sort="Weiner, William" uniqKey="Weiner W" first="William" last="Weiner">William Weiner</name></author><author><name sortKey="Musch, Bruno" sort="Musch, Bruno" uniqKey="Musch B" first="Bruno" last="Musch">Bruno Musch</name></author><author><name sortKey="Kamp, Cornelia" sort="Kamp, Cornelia" uniqKey="Kamp C" first="Cornelia" last="Kamp">Cornelia Kamp</name></author><author><name sortKey="Welsh, Mickie" sort="Welsh, Mickie" uniqKey="Welsh M" first="Mickie" last="Welsh">Mickie Welsh</name></author><author><name sortKey="Shinaman, Aileen" sort="Shinaman, Aileen" uniqKey="Shinaman A" first="Aileen" last="Shinaman">Aileen Shinaman</name></author><author><name sortKey="Pahwa, Rajesh" sort="Pahwa, Rajesh" uniqKey="Pahwa R" first="Rajesh" last="Pahwa">Rajesh Pahwa</name></author><author><name sortKey="Barclay, Lynn" sort="Barclay, Lynn" uniqKey="Barclay L" first="Lynn" last="Barclay">Lynn Barclay</name></author><author><name sortKey="Hubble, Jean" sort="Hubble, Jean" uniqKey="Hubble J" first="Jean" last="Hubble">Jean Hubble</name></author><author><name sortKey="Lewitt, Peter" sort="Lewitt, Peter" uniqKey="Lewitt P" first="Peter" last="Lewitt">Peter Lewitt</name></author><author><name sortKey="Miyasaki, Janis" sort="Miyasaki, Janis" uniqKey="Miyasaki J" first="Janis" last="Miyasaki">Janis Miyasaki</name></author><author><name sortKey="Suchowersky, Oksana" sort="Suchowersky, Oksana" uniqKey="Suchowersky O" first="Oksana" last="Suchowersky">Oksana Suchowersky</name></author><author><name sortKey="Stacy, Mark" sort="Stacy, Mark" uniqKey="Stacy M" first="Mark" last="Stacy">Mark Stacy</name></author><author><name sortKey="Russell, David S" sort="Russell, David S" uniqKey="Russell D" first="David" last="Russell">David. Russell</name></author><author><name sortKey="Ford, Blair" sort="Ford, Blair" uniqKey="Ford B" first="Blair" last="Ford">Blair Ford</name></author><author><name sortKey="Hammerstad, John" sort="Hammerstad, John" uniqKey="Hammerstad J" first="John" last="Hammerstad">John Hammerstad</name></author><author><name sortKey="Riley, David" sort="Riley, David" uniqKey="Riley D" first="David" last="Riley">David Riley</name></author><author><name sortKey="Standaert, David" sort="Standaert, David" uniqKey="Standaert D" first="David" last="Standaert">David Standaert</name></author><author><name sortKey="Wooten, Frederick" sort="Wooten, Frederick" uniqKey="Wooten F" first="Frederick" last="Wooten">Frederick Wooten</name></author><author><name sortKey="Factor, Stewart" sort="Factor, Stewart" uniqKey="Factor S" first="Stewart" last="Factor">Stewart Factor</name></author><author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name><affiliation><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName><orgName type="university" n="3">Baylor College of Medicine</orgName></affiliation></author><author><name sortKey="Atassi, Farah" sort="Atassi, Farah" uniqKey="Atassi F" first="Farah" last="Atassi">Farah Atassi</name></author><author><name sortKey="Kurlan, Roger" sort="Kurlan, Roger" uniqKey="Kurlan R" first="Roger" last="Kurlan">Roger Kurlan</name></author><author><name sortKey="Panisset, Michel" sort="Panisset, Michel" uniqKey="Panisset M" first="Michel" last="Panisset">Michel Panisset</name></author><author><name sortKey="Rajput, Ali" sort="Rajput, Ali" uniqKey="Rajput A" first="Ali" last="Rajput">Ali Rajput</name></author><author><name sortKey="Rodnitzky, Robert" sort="Rodnitzky, Robert" uniqKey="Rodnitzky R" first="Robert" last="Rodnitzky">Robert Rodnitzky</name></author><author><name sortKey="Shults, Cliff" sort="Shults, Cliff" uniqKey="Shults C" first="Cliff" last="Shults">Cliff Shults</name></author><author><name sortKey="Petsinger, Giselle" sort="Petsinger, Giselle" uniqKey="Petsinger G" first="Giselle" last="Petsinger">Giselle Petsinger</name></author><author><name sortKey="Waters, Cheryl" sort="Waters, Cheryl" uniqKey="Waters C" first="Cheryl" last="Waters">Cheryl Waters</name></author><author><name sortKey="Pfeiffer, Ronald" sort="Pfeiffer, Ronald" uniqKey="Pfeiffer R" first="Ronald" last="Pfeiffer">Ronald Pfeiffer</name></author><author><name sortKey="Biglan, Kevin" sort="Biglan, Kevin" uniqKey="Biglan K" first="Kevin" last="Biglan">Kevin Biglan</name></author><author><name sortKey="Borchert, Leona" sort="Borchert, Leona" uniqKey="Borchert L" first="Leona" last="Borchert">Leona Borchert</name></author><author><name sortKey="Montgomery, Amy" sort="Montgomery, Amy" uniqKey="Montgomery A" first="Amy" last="Montgomery">Amy Montgomery</name></author><author><name sortKey="Sutherland, Laura" sort="Sutherland, Laura" uniqKey="Sutherland L" first="Laura" last="Sutherland">Laura Sutherland</name></author><author><name sortKey="Weeks, Carolyn" sort="Weeks, Carolyn" uniqKey="Weeks C" first="Carolyn" last="Weeks">Carolyn Weeks</name></author><author><name sortKey="Deangelis, Maryan" sort="Deangelis, Maryan" uniqKey="Deangelis M" first="Maryan" last="Deangelis">Maryan Deangelis</name></author><author><name sortKey="Sime, Elspeth" sort="Sime, Elspeth" uniqKey="Sime E" first="Elspeth" last="Sime">Elspeth Sime</name></author><author><name sortKey="Wood, Susan" sort="Wood, Susan" uniqKey="Wood S" first="Susan" last="Wood">Susan Wood</name></author><author><name sortKey="Pantella, Carol" sort="Pantella, Carol" uniqKey="Pantella C" first="Carol" last="Pantella">Carol Pantella</name></author><author><name sortKey="Harrigan, Mary" sort="Harrigan, Mary" uniqKey="Harrigan M" first="Mary" last="Harrigan">Mary Harrigan</name></author><author><name sortKey="Fussell, Barbara" sort="Fussell, Barbara" uniqKey="Fussell B" first="Barbara" last="Fussell">Barbara Fussell</name></author><author><name sortKey="Dillon, Sandra" sort="Dillon, Sandra" uniqKey="Dillon S" first="Sandra" last="Dillon">Sandra Dillon</name></author><author><name sortKey="Alexander Brown, Barbara" sort="Alexander Brown, Barbara" uniqKey="Alexander Brown B" first="Barbara" last="Alexander">Barbara Alexander</name></author><author><name sortKey="Rainey, Pamela" sort="Rainey, Pamela" uniqKey="Rainey P" first="Pamela" last="Rainey">Pamela Rainey</name></author><author><name sortKey="Tennis, Marsha" sort="Tennis, Marsha" uniqKey="Tennis M" first="Marsha" last="Tennis">Marsha Tennis</name></author><author><name sortKey="Rost Ruffner, Elke" sort="Rost Ruffner, Elke" uniqKey="Rost Ruffner E" first="Elke" last="Rost">Elke Rost</name></author><author><name sortKey="Brown, Diane" sort="Brown, Diane" uniqKey="Brown D" first="Diane" last="Brown">Diane Brown</name></author><author><name sortKey="Evans, Sharon" sort="Evans, Sharon" uniqKey="Evans S" first="Sharon" last="Evans">Sharon Evans</name></author><author><name sortKey="Berry, Debra" sort="Berry, Debra" uniqKey="Berry D" first="Debra" last="Berry">Debra Berry</name></author><author><name sortKey="Hall, Jean" sort="Hall, Jean" uniqKey="Hall J" first="Jean" last="Hall">Jean Hall</name></author><author><name sortKey="Shirley, Theresa" sort="Shirley, Theresa" uniqKey="Shirley T" first="Theresa" last="Shirley">Theresa Shirley</name></author><author><name sortKey="Dobson, Judith" sort="Dobson, Judith" uniqKey="Dobson J" first="Judith" last="Dobson">Judith Dobson</name></author><author><name sortKey="Fontaine, Deborah" sort="Fontaine, Deborah" uniqKey="Fontaine D" first="Deborah" last="Fontaine">Deborah Fontaine</name></author><author><name sortKey="Pfeiffer, Brenda" sort="Pfeiffer, Brenda" uniqKey="Pfeiffer B" first="Brenda" last="Pfeiffer">Brenda Pfeiffer</name></author><author><name sortKey="Brocht, Alicia" sort="Brocht, Alicia" uniqKey="Brocht A" first="Alicia" last="Brocht">Alicia Brocht</name></author><author><name sortKey="Bennett, Susan" sort="Bennett, Susan" uniqKey="Bennett S" first="Susan" last="Bennett">Susan Bennett</name></author><author><name sortKey="Daigneault, Susan" sort="Daigneault, Susan" uniqKey="Daigneault S" first="Susan" last="Daigneault">Susan Daigneault</name></author><author><name sortKey="Hodgeman, Karen" sort="Hodgeman, Karen" uniqKey="Hodgeman K" first="Karen" last="Hodgeman">Karen Hodgeman</name></author><author><name sortKey="O Connell, Carolynn" sort="O Connell, Carolynn" uniqKey="O Connell C" first="Carolynn" last="O">Carolynn O</name></author><author><name sortKey="Ross, Tori" sort="Ross, Tori" uniqKey="Ross T" first="Tori" last="Ross">Tori Ross</name></author><author><name sortKey="Richard, Karen" sort="Richard, Karen" uniqKey="Richard K" first="Karen" last="Richard">Karen Richard</name></author><author><name sortKey="Watts, Arthur" sort="Watts, Arthur" uniqKey="Watts A" first="Arthur" last="Watts">Arthur Watts</name></author></analytic><series><title level="j">Archives of neurology</title><idno type="ISSN">0003-9942</idno><imprint><date when="2004" type="published">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Benzothiazoles</term><term>Double-Blind Method</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Levodopa (adverse effects)</term><term>Levodopa (therapeutic use)</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (drug therapy)</term><term>Parkinson Disease (physiopathology)</term><term>Parkinson Disease (psychology)</term><term>Proportional Hazards Models</term><term>Quality of Life (psychology)</term><term>Severity of Illness Index</term><term>Thiazoles (adverse effects)</term><term>Thiazoles (therapeutic use)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Levodopa</term><term>Thiazoles</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Levodopa</term><term>Thiazoles</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Benzothiazoles</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Parkinson Disease</term><term>Quality of Life</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Double-Blind Method</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Proportional Hazards Models</term><term>Severity of Illness Index</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The best way to initiate dopaminergic therapy for early Parkinson disease remains unclear.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">15262734</PMID><DateCreated><Year>2004</Year><Month>07</Month><Day>20</Day></DateCreated><DateCompleted><Year>2004</Year><Month>08</Month><Day>10</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0003-9942</ISSN><JournalIssue CitedMedium="Print"><Volume>61</Volume><Issue>7</Issue><PubDate><Year>2004</Year><Month>Jul</Month></PubDate></JournalIssue><Title>Archives of neurology</Title><ISOAbbreviation>Arch. Neurol.</ISOAbbreviation></Journal><ArticleTitle>Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial.</ArticleTitle><Pagination><MedlinePgn>1044-53</MedlinePgn></Pagination><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The best way to initiate dopaminergic therapy for early Parkinson disease remains unclear.</AbstractText><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To compare initial treatment with pramipexole vs levodopa in early Parkinson disease, followed by levodopa supplementation, with respect to the development of dopaminergic motor complications, other adverse events, and functional and quality-of-life outcomes.</AbstractText><AbstractText Label="DESIGN" NlmCategory="METHODS">Multicenter, parallel-group, double-blind, randomized controlled trial.</AbstractText><AbstractText Label="SETTING" NlmCategory="METHODS">Academic movement disorders clinics at 22 sites in the United States and Canada.</AbstractText><AbstractText Label="PATIENTS" NlmCategory="METHODS">Patients with early Parkinson disease (N = 301) who required dopaminergic therapy to treat emerging disability, enrolled between October 1996 and August 1997 and observed until August 2001.</AbstractText><AbstractText Label="INTERVENTION" NlmCategory="METHODS">Subjects were randomly assigned to receive 0.5 mg of pramipexole 3 times per day with levodopa placebo (n = 151) or 25/100 mg of carbidopa/levodopa 3 times per day with pramipexole placebo (n = 150). Dosage was escalated during the first 10 weeks for patients with ongoing disability. Thereafter, investigators were permitted to add open-label levodopa or other antiparkinsonian medications to treat ongoing or emerging disability.</AbstractText><AbstractText Label="MAIN OUTCOME MEASURES" NlmCategory="METHODS">Time to the first occurrence of dopaminergic complications: wearing off, dyskinesias, on-off fluctuations, and freezing; changes in the Unified Parkinson's Disease Rating Scale and quality-of-life scales; and adverse events.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Initial pramipexole treatment resulted in a significant reduction in the risk of developing dyskinesias (24.5% vs 54%; hazard ratio, 0.37; 95% confidence interval [CI], 0.25-0.56; P<.001) and wearing off (47% vs 62.7%; hazard ratio, 0.68; 95% CI, 0.49-0.63; P =.02). Initial levodopa treatment resulted in a significant reduction in the risk of freezing (25.3% vs 37.1%; hazard ratio, 1.7; 95% CI, 1.11-2.59; P =.01). By 48 months, the occurrence of disabling dyskinesias was uncommon and did not significantly differ between the 2 groups. The mean improvement in the total Unified Parkinson's Disease Rating Scale score from baseline to 48 months was greater in the levodopa group than in the pramipexole group (2 +/- 15.4 points vs -3.2 +/- 17.3 points, P =.003). Somnolence (36% vs 21%, P =.005) and edema (42% vs 15%, P<.001) were more common in pramipexole-treated subjects than in levodopa-treated subjects. Mean changes in quality-of-life scores did not differ between the groups.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Initial treatment with pramipexole resulted in lower incidences of dyskinesias and wearing off compared with initial treatment with levodopa. Initial treatment with levodopa resulted in lower incidences of freezing, somnolence, and edema and provided for better symptomatic control, as measured by the Unified Parkinson's Disease Rating Scale, compared with initial treatment with pramipexole. Both options resulted in similar quality of life. Levodopa and pramipexole both appear to be reasonable options as initial dopaminergic therapy for Parkinson disease, but they are associated with different efficacy and adverse-effect profiles.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Holloway</LastName><ForeName>Robert G</ForeName><Initials>RG</Initials><AffiliationInfo><Affiliation>Department of Neurology, University of Rochester, 1351 Mt. Hope Avenue, Suite 220, Rochester, NY 14620, USA. robert.holloway@ctcc.rochester.edu</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shoulson</LastName><ForeName>Ira</ForeName><Initials>I</Initials></Author><Author ValidYN="Y"><LastName>Fahn</LastName><ForeName>Stanley</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Kieburtz</LastName><ForeName>Karl</ForeName><Initials>K</Initials></Author><Author ValidYN="Y"><LastName>Lang</LastName><ForeName>Anthony</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Marek</LastName><ForeName>Kenneth</ForeName><Initials>K</Initials></Author><Author ValidYN="Y"><LastName>McDermott</LastName><ForeName>Michael</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Seibyl</LastName><ForeName>John</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Weiner</LastName><ForeName>William</ForeName><Initials>W</Initials></Author><Author ValidYN="Y"><LastName>Musch</LastName><ForeName>Bruno</ForeName><Initials>B</Initials></Author><Author ValidYN="Y"><LastName>Kamp</LastName><ForeName>Cornelia</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Welsh</LastName><ForeName>Mickie</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Shinaman</LastName><ForeName>Aileen</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Pahwa</LastName><ForeName>Rajesh</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Barclay</LastName><ForeName>Lynn</ForeName><Initials>L</Initials></Author><Author ValidYN="Y"><LastName>Hubble</LastName><ForeName>Jean</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>LeWitt</LastName><ForeName>Peter</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Miyasaki</LastName><ForeName>Janis</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Suchowersky</LastName><ForeName>Oksana</ForeName><Initials>O</Initials></Author><Author ValidYN="Y"><LastName>Stacy</LastName><ForeName>Mark</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Russell</LastName><ForeName>David S</ForeName><Initials>DS</Initials></Author><Author ValidYN="Y"><LastName>Ford</LastName><ForeName>Blair</ForeName><Initials>B</Initials></Author><Author ValidYN="Y"><LastName>Hammerstad</LastName><ForeName>John</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Riley</LastName><ForeName>David</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Standaert</LastName><ForeName>David</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Wooten</LastName><ForeName>Frederick</ForeName><Initials>F</Initials></Author><Author ValidYN="Y"><LastName>Factor</LastName><ForeName>Stewart</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Jankovic</LastName><ForeName>Joseph</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Atassi</LastName><ForeName>Farah</ForeName><Initials>F</Initials></Author><Author ValidYN="Y"><LastName>Kurlan</LastName><ForeName>Roger</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Panisset</LastName><ForeName>Michel</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Rajput</LastName><ForeName>Ali</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Rodnitzky</LastName><ForeName>Robert</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Shults</LastName><ForeName>Cliff</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Petsinger</LastName><ForeName>Giselle</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Waters</LastName><ForeName>Cheryl</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Pfeiffer</LastName><ForeName>Ronald</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Biglan</LastName><ForeName>Kevin</ForeName><Initials>K</Initials></Author><Author ValidYN="Y"><LastName>Borchert</LastName><ForeName>Leona</ForeName><Initials>L</Initials></Author><Author ValidYN="Y"><LastName>Montgomery</LastName><ForeName>Amy</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Sutherland</LastName><ForeName>Laura</ForeName><Initials>L</Initials></Author><Author ValidYN="Y"><LastName>Weeks</LastName><ForeName>Carolyn</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>DeAngelis</LastName><ForeName>Maryan</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Sime</LastName><ForeName>Elspeth</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Wood</LastName><ForeName>Susan</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Pantella</LastName><ForeName>Carol</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Harrigan</LastName><ForeName>Mary</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Fussell</LastName><ForeName>Barbara</ForeName><Initials>B</Initials></Author><Author ValidYN="Y"><LastName>Dillon</LastName><ForeName>Sandra</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Alexander-Brown</LastName><ForeName>Barbara</ForeName><Initials>B</Initials></Author><Author ValidYN="Y"><LastName>Rainey</LastName><ForeName>Pamela</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Tennis</LastName><ForeName>Marsha</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Rost-Ruffner</LastName><ForeName>Elke</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Brown</LastName><ForeName>Diane</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Evans</LastName><ForeName>Sharon</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Berry</LastName><ForeName>Debra</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Hall</LastName><ForeName>Jean</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Shirley</LastName><ForeName>Theresa</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Dobson</LastName><ForeName>Judith</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Fontaine</LastName><ForeName>Deborah</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Pfeiffer</LastName><ForeName>Brenda</ForeName><Initials>B</Initials></Author><Author ValidYN="Y"><LastName>Brocht</LastName><ForeName>Alicia</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Bennett</LastName><ForeName>Susan</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Daigneault</LastName><ForeName>Susan</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Hodgeman</LastName><ForeName>Karen</ForeName><Initials>K</Initials></Author><Author ValidYN="Y"><LastName>O'Connell</LastName><ForeName>Carolynn</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Ross</LastName><ForeName>Tori</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Richard</LastName><ForeName>Karen</ForeName><Initials>K</Initials></Author><Author ValidYN="Y"><LastName>Watts</LastName><ForeName>Arthur</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><CollectiveName>Parkinson Study Group</CollectiveName></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>RR 00044</GrantID><Acronym>RR</Acronym><Agency>NCRR NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>RR 01066</GrantID><Acronym>RR</Acronym><Agency>NCRR NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016430">Clinical Trial</PublicationType><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016448">Multicenter Study</PublicationType><PublicationType UI="D016449">Randomized Controlled Trial</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D013487">Research Support, U.S. Gov't, P.H.S.</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Arch Neurol</MedlineTA><NlmUniqueID>0372436</NlmUniqueID><ISSNLinking>0003-9942</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D052160">Benzothiazoles</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D013844">Thiazoles</NameOfSubstance></Chemical><Chemical><RegistryNumber>46627O600J</RegistryNumber><NameOfSubstance UI="D007980">Levodopa</NameOfSubstance></Chemical><Chemical><RegistryNumber>83619PEU5T</RegistryNumber><NameOfSubstance UI="C061333">pramipexole</NameOfSubstance></Chemical></ChemicalList><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="ErratumIn"><RefSource>Arch Neurol. 2005 Mar;62(3):430</RefSource></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D052160">Benzothiazoles</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004311">Double-Blind Method</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005500">Follow-Up Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D007980">Levodopa</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000627">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D010300">Parkinson Disease</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000188">drug therapy</QualifierName><QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName><QualifierName MajorTopicYN="N" UI="Q000523">psychology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D016016">Proportional Hazards Models</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011788">Quality of Life</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000523">psychology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012720">Severity of Illness Index</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D013844">Thiazoles</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000627">therapeutic use</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2004</Year><Month>7</Month><Day>21</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2004</Year><Month>8</Month><Day>11</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2004</Year><Month>7</Month><Day>21</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">15262734</ArticleId><ArticleId IdType="doi">10.1001/archneur.61.7.1044</ArticleId><ArticleId IdType="pii">61/7/1044</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Texas</li><li>État de New York</li></region><settlement><li>Houston</li></settlement><orgName><li>Baylor College of Medicine</li></orgName></list><tree><noCountry><name sortKey="Alexander Brown, Barbara" sort="Alexander Brown, Barbara" uniqKey="Alexander Brown B" first="Barbara" last="Alexander">Barbara Alexander</name><name sortKey="Atassi, Farah" sort="Atassi, Farah" uniqKey="Atassi F" first="Farah" last="Atassi">Farah Atassi</name><name sortKey="Barclay, Lynn" sort="Barclay, Lynn" uniqKey="Barclay L" first="Lynn" last="Barclay">Lynn Barclay</name><name sortKey="Bennett, Susan" sort="Bennett, Susan" uniqKey="Bennett S" first="Susan" last="Bennett">Susan Bennett</name><name sortKey="Berry, Debra" sort="Berry, Debra" uniqKey="Berry D" first="Debra" last="Berry">Debra Berry</name><name sortKey="Biglan, Kevin" sort="Biglan, Kevin" uniqKey="Biglan K" first="Kevin" last="Biglan">Kevin Biglan</name><name sortKey="Borchert, Leona" sort="Borchert, Leona" uniqKey="Borchert L" first="Leona" last="Borchert">Leona Borchert</name><name sortKey="Brocht, Alicia" sort="Brocht, Alicia" uniqKey="Brocht A" first="Alicia" last="Brocht">Alicia Brocht</name><name sortKey="Brown, Diane" sort="Brown, Diane" uniqKey="Brown D" first="Diane" last="Brown">Diane Brown</name><name sortKey="Daigneault, Susan" sort="Daigneault, Susan" uniqKey="Daigneault S" first="Susan" last="Daigneault">Susan Daigneault</name><name sortKey="Deangelis, Maryan" sort="Deangelis, Maryan" uniqKey="Deangelis M" first="Maryan" last="Deangelis">Maryan Deangelis</name><name sortKey="Dillon, Sandra" sort="Dillon, Sandra" uniqKey="Dillon S" first="Sandra" last="Dillon">Sandra Dillon</name><name sortKey="Dobson, Judith" sort="Dobson, Judith" uniqKey="Dobson J" first="Judith" last="Dobson">Judith Dobson</name><name sortKey="Evans, Sharon" sort="Evans, Sharon" uniqKey="Evans S" first="Sharon" last="Evans">Sharon Evans</name><name sortKey="Factor, Stewart" sort="Factor, Stewart" uniqKey="Factor S" first="Stewart" last="Factor">Stewart Factor</name><name sortKey="Fahn, Stanley" sort="Fahn, Stanley" uniqKey="Fahn S" first="Stanley" last="Fahn">Stanley Fahn</name><name sortKey="Fontaine, Deborah" sort="Fontaine, Deborah" uniqKey="Fontaine D" first="Deborah" last="Fontaine">Deborah Fontaine</name><name sortKey="Ford, Blair" sort="Ford, Blair" uniqKey="Ford B" first="Blair" last="Ford">Blair Ford</name><name sortKey="Fussell, Barbara" sort="Fussell, Barbara" uniqKey="Fussell B" first="Barbara" last="Fussell">Barbara Fussell</name><name sortKey="Hall, Jean" sort="Hall, Jean" uniqKey="Hall J" first="Jean" last="Hall">Jean Hall</name><name sortKey="Hammerstad, John" sort="Hammerstad, John" uniqKey="Hammerstad J" first="John" last="Hammerstad">John Hammerstad</name><name sortKey="Harrigan, Mary" sort="Harrigan, Mary" uniqKey="Harrigan M" first="Mary" last="Harrigan">Mary Harrigan</name><name sortKey="Hodgeman, Karen" sort="Hodgeman, Karen" uniqKey="Hodgeman K" first="Karen" last="Hodgeman">Karen Hodgeman</name><name sortKey="Hubble, Jean" sort="Hubble, Jean" uniqKey="Hubble J" first="Jean" last="Hubble">Jean Hubble</name><name sortKey="Kamp, Cornelia" sort="Kamp, Cornelia" uniqKey="Kamp C" first="Cornelia" last="Kamp">Cornelia Kamp</name><name sortKey="Kieburtz, Karl" sort="Kieburtz, Karl" uniqKey="Kieburtz K" first="Karl" last="Kieburtz">Karl Kieburtz</name><name sortKey="Kurlan, Roger" sort="Kurlan, Roger" uniqKey="Kurlan R" first="Roger" last="Kurlan">Roger Kurlan</name><name sortKey="Lang, Anthony" sort="Lang, Anthony" uniqKey="Lang A" first="Anthony" last="Lang">Anthony Lang</name><name sortKey="Lewitt, Peter" sort="Lewitt, Peter" uniqKey="Lewitt P" first="Peter" last="Lewitt">Peter Lewitt</name><name sortKey="Marek, Kenneth" sort="Marek, Kenneth" uniqKey="Marek K" first="Kenneth" last="Marek">Kenneth Marek</name><name sortKey="Mcdermott, Michael" sort="Mcdermott, Michael" uniqKey="Mcdermott M" first="Michael" last="Mcdermott">Michael Mcdermott</name><name sortKey="Miyasaki, Janis" sort="Miyasaki, Janis" uniqKey="Miyasaki J" first="Janis" last="Miyasaki">Janis Miyasaki</name><name sortKey="Montgomery, Amy" sort="Montgomery, Amy" uniqKey="Montgomery A" first="Amy" last="Montgomery">Amy Montgomery</name><name sortKey="Musch, Bruno" sort="Musch, Bruno" uniqKey="Musch B" first="Bruno" last="Musch">Bruno Musch</name><name sortKey="O Connell, Carolynn" sort="O Connell, Carolynn" uniqKey="O Connell C" first="Carolynn" last="O">Carolynn O</name><name sortKey="Pahwa, Rajesh" sort="Pahwa, Rajesh" uniqKey="Pahwa R" first="Rajesh" last="Pahwa">Rajesh Pahwa</name><name sortKey="Panisset, Michel" sort="Panisset, Michel" uniqKey="Panisset M" first="Michel" last="Panisset">Michel Panisset</name><name sortKey="Pantella, Carol" sort="Pantella, Carol" uniqKey="Pantella C" first="Carol" last="Pantella">Carol Pantella</name><name sortKey="Petsinger, Giselle" sort="Petsinger, Giselle" uniqKey="Petsinger G" first="Giselle" last="Petsinger">Giselle Petsinger</name><name sortKey="Pfeiffer, Brenda" sort="Pfeiffer, Brenda" uniqKey="Pfeiffer B" first="Brenda" last="Pfeiffer">Brenda Pfeiffer</name><name sortKey="Pfeiffer, Ronald" sort="Pfeiffer, Ronald" uniqKey="Pfeiffer R" first="Ronald" last="Pfeiffer">Ronald Pfeiffer</name><name sortKey="Rainey, Pamela" sort="Rainey, Pamela" uniqKey="Rainey P" first="Pamela" last="Rainey">Pamela Rainey</name><name sortKey="Rajput, Ali" sort="Rajput, Ali" uniqKey="Rajput A" first="Ali" last="Rajput">Ali Rajput</name><name sortKey="Richard, Karen" sort="Richard, Karen" uniqKey="Richard K" first="Karen" last="Richard">Karen Richard</name><name sortKey="Riley, David" sort="Riley, David" uniqKey="Riley D" first="David" last="Riley">David Riley</name><name sortKey="Rodnitzky, Robert" sort="Rodnitzky, Robert" uniqKey="Rodnitzky R" first="Robert" last="Rodnitzky">Robert Rodnitzky</name><name sortKey="Ross, Tori" sort="Ross, Tori" uniqKey="Ross T" first="Tori" last="Ross">Tori Ross</name><name sortKey="Rost Ruffner, Elke" sort="Rost Ruffner, Elke" uniqKey="Rost Ruffner E" first="Elke" last="Rost">Elke Rost</name><name sortKey="Russell, David S" sort="Russell, David S" uniqKey="Russell D" first="David" last="Russell">David. Russell</name><name sortKey="Seibyl, John" sort="Seibyl, John" uniqKey="Seibyl J" first="John" last="Seibyl">John Seibyl</name><name sortKey="Shinaman, Aileen" sort="Shinaman, Aileen" uniqKey="Shinaman A" first="Aileen" last="Shinaman">Aileen Shinaman</name><name sortKey="Shirley, Theresa" sort="Shirley, Theresa" uniqKey="Shirley T" first="Theresa" last="Shirley">Theresa Shirley</name><name sortKey="Shoulson, Ira" sort="Shoulson, Ira" uniqKey="Shoulson I" first="Ira" last="Shoulson">Ira Shoulson</name><name sortKey="Shults, Cliff" sort="Shults, Cliff" uniqKey="Shults C" first="Cliff" last="Shults">Cliff Shults</name><name sortKey="Sime, Elspeth" sort="Sime, Elspeth" uniqKey="Sime E" first="Elspeth" last="Sime">Elspeth Sime</name><name sortKey="Stacy, Mark" sort="Stacy, Mark" uniqKey="Stacy M" first="Mark" last="Stacy">Mark Stacy</name><name sortKey="Standaert, David" sort="Standaert, David" uniqKey="Standaert D" first="David" last="Standaert">David Standaert</name><name sortKey="Suchowersky, Oksana" sort="Suchowersky, Oksana" uniqKey="Suchowersky O" first="Oksana" last="Suchowersky">Oksana Suchowersky</name><name sortKey="Sutherland, Laura" sort="Sutherland, Laura" uniqKey="Sutherland L" first="Laura" last="Sutherland">Laura Sutherland</name><name sortKey="Tennis, Marsha" sort="Tennis, Marsha" uniqKey="Tennis M" first="Marsha" last="Tennis">Marsha Tennis</name><name sortKey="Waters, Cheryl" sort="Waters, Cheryl" uniqKey="Waters C" first="Cheryl" last="Waters">Cheryl Waters</name><name sortKey="Watts, Arthur" sort="Watts, Arthur" uniqKey="Watts A" first="Arthur" last="Watts">Arthur Watts</name><name sortKey="Weeks, Carolyn" sort="Weeks, Carolyn" uniqKey="Weeks C" first="Carolyn" last="Weeks">Carolyn Weeks</name><name sortKey="Weiner, William" sort="Weiner, William" uniqKey="Weiner W" first="William" last="Weiner">William Weiner</name><name sortKey="Welsh, Mickie" sort="Welsh, Mickie" uniqKey="Welsh M" first="Mickie" last="Welsh">Mickie Welsh</name><name sortKey="Wood, Susan" sort="Wood, Susan" uniqKey="Wood S" first="Susan" last="Wood">Susan Wood</name><name sortKey="Wooten, Frederick" sort="Wooten, Frederick" uniqKey="Wooten F" first="Frederick" last="Wooten">Frederick Wooten</name></noCountry><country name="États-Unis"><region name="État de New York"><name sortKey="Holloway, Robert G" sort="Holloway, Robert G" uniqKey="Holloway R" first="Robert" last="Holloway">Robert. Holloway</name></region><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/JankovicV1/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000075 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 000075 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= JankovicV1
|flux= Ncbi
|étape= Merge
|type= RBID
|clé= pubmed:15262734
|texte= Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:15262734" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \
| NlmPubMed2Wicri -a JankovicV1
| This area was generated with Dilib version V0.6.19. |  |