Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results.
Identifieur interne : 000211 ( Ncbi/Curation ); précédent : 000210; suivant : 000212Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results.
Auteurs : Christopher. Goetz [États-Unis] ; Barbara. Tilley ; Stephanie. Shaftman ; Glenn. Stebbins ; Stanley Fahn ; Pablo Martinez ; Werner Poewe ; Cristina Sampaio ; Matthew. Stern ; Richard Dodel ; Bruno Dubois ; Robert Holloway ; Joseph Jankovic [États-Unis] ; Jaime Kulisevsky ; Anthony. Lang ; Andrew Lees ; Sue Leurgans ; Peter. Lewitt ; David Nyenhuis ; C Olanow ; Olivier Rascol ; Anette Schrag ; Jeanne. Teresi ; Jacobus. Van ; Nancy LapelleSource :
- Movement disorders : official journal of the Movement Disorder Society ; 2008.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Disability Evaluation, Factor Analysis, Statistical, Female, Humans, Male, Middle Aged, Movement Disorders, Neurologic Examination (methods), Parkinson Disease (diagnosis), Parkinson Disease (physiopathology), Severity of Illness Index, Societies, Medical (standards).
- MESH :
- diagnosis : Parkinson Disease.
- methods : Neurologic Examination.
- physiopathology : Parkinson Disease.
- standards : Societies, Medical.
- Adult, Aged, Aged, 80 and over, Disability Evaluation, Factor Analysis, Statistical, Female, Humans, Male, Middle Aged, Movement Disorders, Severity of Illness Index.
Abstract
We present a clinimetric assessment of the Movement Disorder Society (MDS)-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS). The MDS-UDPRS Task Force revised and expanded the UPDRS using recommendations from a published critique. The MDS-UPDRS has four parts, namely, I: Non-motor Experiences of Daily Living; II: Motor Experiences of Daily Living; III: Motor Examination; IV: Motor Complications. Twenty questions are completed by the patient/caregiver. Item-specific instructions and an appendix of complementary additional scales are provided. Movement disorder specialists and study coordinators administered the UPDRS (55 items) and MDS-UPDRS (65 items) to 877 English speaking (78% non-Latino Caucasian) patients with Parkinson's disease from 39 sites. We compared the two scales using correlative techniques and factor analysis. The MDS-UPDRS showed high internal consistency (Cronbach's alpha = 0.79-0.93 across parts) and correlated with the original UPDRS (rho = 0.96). MDS-UPDRS across-part correlations ranged from 0.22 to 0.66. Reliable factor structures for each part were obtained (comparative fit index > 0.90 for each part), which support the use of sum scores for each part in preference to a total score of all parts. The combined clinimetric results of this study support the validity of the MDS-UPDRS for rating PD.
DOI: 10.1002/mds.22340
PubMed: 19025984
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<author><name sortKey="Goetz, Christopher G" sort="Goetz, Christopher G" uniqKey="Goetz C" first="Christopher" last="Goetz">Christopher. Goetz</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA. cgoetz@rush.edu</nlm:affiliation>
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<term>Factor Analysis, Statistical</term>
<term>Female</term>
<term>Humans</term>
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<term>Middle Aged</term>
<term>Movement Disorders</term>
<term>Neurologic Examination (methods)</term>
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<term>Aged</term>
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<term>Factor Analysis, Statistical</term>
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<front><div type="abstract" xml:lang="en">We present a clinimetric assessment of the Movement Disorder Society (MDS)-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS). The MDS-UDPRS Task Force revised and expanded the UPDRS using recommendations from a published critique. The MDS-UPDRS has four parts, namely, I: Non-motor Experiences of Daily Living; II: Motor Experiences of Daily Living; III: Motor Examination; IV: Motor Complications. Twenty questions are completed by the patient/caregiver. Item-specific instructions and an appendix of complementary additional scales are provided. Movement disorder specialists and study coordinators administered the UPDRS (55 items) and MDS-UPDRS (65 items) to 877 English speaking (78% non-Latino Caucasian) patients with Parkinson's disease from 39 sites. We compared the two scales using correlative techniques and factor analysis. The MDS-UPDRS showed high internal consistency (Cronbach's alpha = 0.79-0.93 across parts) and correlated with the original UPDRS (rho = 0.96). MDS-UPDRS across-part correlations ranged from 0.22 to 0.66. Reliable factor structures for each part were obtained (comparative fit index > 0.90 for each part), which support the use of sum scores for each part in preference to a total score of all parts. The combined clinimetric results of this study support the validity of the MDS-UPDRS for rating PD.</div>
</front>
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