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Apolipoprotein E controls the risk and age at onset of Parkinson disease.

Identifieur interne : 000073 ( Ncbi/Curation ); précédent : 000072; suivant : 000074

Apolipoprotein E controls the risk and age at onset of Parkinson disease.

Auteurs : Y Li [États-Unis] ; M Hauser ; W Scott ; E Martin ; M Booze ; X Qin ; J Walter ; M Nance ; J Hubble ; W Koller ; R. Pahwa ; M Stern ; B Hiner ; Joseph Jankovic [États-Unis] ; C Goetz ; G Small ; F. Mastaglia ; J Haines ; M Pericak ; J Vance

Source :

RBID : pubmed:15184605

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English descriptors

Abstract

Similarities between Alzheimer disease (AD) and Parkinson disease (PD) suggest a possible role for apolipoprotein E (APOE) in PD. Most previous studies seeking to establish such a link used case-control datasets and results have been inconsistent.

PubMed: 15184605

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pubmed:15184605

Le document en format XML

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<term>Age of Onset</term>
<term>Aged</term>
<term>Alleles</term>
<term>Apolipoprotein E3</term>
<term>Apolipoprotein E4</term>
<term>Apolipoproteins E (genetics)</term>
<term>Apolipoproteins E (physiology)</term>
<term>Australia (epidemiology)</term>
<term>Cognition</term>
<term>Dementia (epidemiology)</term>
<term>Dementia (genetics)</term>
<term>Female</term>
<term>Gene Frequency</term>
<term>Genetic Predisposition to Disease</term>
<term>Genotype</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
<term>Parkinson Disease (epidemiology)</term>
<term>Parkinson Disease (genetics)</term>
<term>Parkinson Disease (psychology)</term>
<term>Pedigree</term>
<term>Risk</term>
<term>United States (epidemiology)</term>
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<term>Apolipoproteins E</term>
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<term>Apolipoprotein E3</term>
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<term>Parkinson Disease</term>
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<term>Age of Onset</term>
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<term>Alleles</term>
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<term>Genetic Predisposition to Disease</term>
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<front>
<div type="abstract" xml:lang="en">Similarities between Alzheimer disease (AD) and Parkinson disease (PD) suggest a possible role for apolipoprotein E (APOE) in PD. Most previous studies seeking to establish such a link used case-control datasets and results have been inconsistent.</div>
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