Epidemiology and management of essential tremor in children.
Identifieur interne : 000250 ( Ncbi/Checkpoint ); précédent : 000249; suivant : 000251Epidemiology and management of essential tremor in children.
Auteurs : Joseph Ferrara [États-Unis] ; Joseph Jankovic [États-Unis]Source :
- Paediatric drugs [ 1174-5878 ] ; 2009.
English descriptors
- KwdEn :
- Adolescent, Adrenergic beta-Antagonists (therapeutic use), Adult, Aged, Animals, Child, Clinical Trials as Topic, Diagnosis, Differential, Essential Tremor (drug therapy), Essential Tremor (epidemiology), Essential Tremor (physiopathology), Female, Humans, Male, Middle Aged, Propranolol (therapeutic use), Risk Factors, Sex Factors.
- MESH :
- chemical , therapeutic use : Adrenergic beta-Antagonists, Propranolol.
- drug therapy : Essential Tremor.
- epidemiology : Essential Tremor.
- physiopathology : Essential Tremor.
- Adolescent, Adult, Aged, Animals, Child, Clinical Trials as Topic, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Risk Factors, Sex Factors.
Abstract
Essential tremor (ET) is a common, often familial, movement disorder characterized by tremor of the limbs, head, and voice. Epidemiological surveys indicate that up to 5% of the adult population has ET, and 5-30% of adults with ET report symptom onset during childhood. There is, however, little published regarding ET in the pediatric population, and no prospective studies targeted specifically to children. Retrospective studies from subspecialty movement disorder clinics indicate that childhood-onset ET is usually hereditary, begins at a mean age of 6 years, and affects boys three times as often as girls. While ET occasionally results in disability during childhood, only one-quarter of children seeing a neurologist for ET require pharmacotherapy. Small case series suggest that propranolol is effective in approximately 50% of children with ET, but controlled treatment trials are lacking.
DOI: 10.2165/11316050-000000000-00000
PubMed: 19725596
Affiliations:
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<front><div type="abstract" xml:lang="en">Essential tremor (ET) is a common, often familial, movement disorder characterized by tremor of the limbs, head, and voice. Epidemiological surveys indicate that up to 5% of the adult population has ET, and 5-30% of adults with ET report symptom onset during childhood. There is, however, little published regarding ET in the pediatric population, and no prospective studies targeted specifically to children. Retrospective studies from subspecialty movement disorder clinics indicate that childhood-onset ET is usually hereditary, begins at a mean age of 6 years, and affects boys three times as often as girls. While ET occasionally results in disability during childhood, only one-quarter of children seeing a neurologist for ET require pharmacotherapy. Small case series suggest that propranolol is effective in approximately 50% of children with ET, but controlled treatment trials are lacking.</div>
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