Neuro-ophthalmic findings in progressive supranuclear palsy.
Identifieur interne : 001F55 ( Main/Merge ); précédent : 001F54; suivant : 001F56Neuro-ophthalmic findings in progressive supranuclear palsy.
Auteurs : D Friedman ; Joseph Jankovic [États-Unis] ; J MccrarySource :
- Journal of clinical neuro-ophthalmology [ 0272-846X ] ; 1992.
English descriptors
- KwdEn :
- Aged, Diagnosis, Differential, Eye Diseases (diagnosis), Eye Diseases (physiopathology), Eye Movements, Eyelid Diseases (diagnosis), Eyelid Diseases (physiopathology), Female, Fixation, Ocular, Humans, Male, Ocular Motility Disorders (physiopathology), Parkinson Disease (diagnosis), Parkinson Disease (physiopathology), Supranuclear Palsy, Progressive (physiopathology).
- MESH :
- diagnosis : Eye Diseases, Eyelid Diseases, Parkinson Disease.
- physiopathology : Eye Diseases, Eyelid Diseases, Ocular Motility Disorders, Parkinson Disease, Supranuclear Palsy, Progressive.
- Aged, Diagnosis, Differential, Eye Movements, Female, Fixation, Ocular, Humans, Male.
Abstract
We studied 104 patients with progressive supranuclear palsy (PSP), 38 of whom were examined by both a neurologist and a neuro-ophthalmologist. Neuro-ophthalmic findings that may help differentiate PSP from Parkinson's disease include vertical supranuclear ophthalmoparesis and fixation instability. Eyelid abnormalities, particularly lid retraction, blepharospasm, and "apraxia" of eyelid opening and closure, were important distinguishing signs. Although downgaze palsy is felt to be the clinical hallmark of PSP, upgaze and downgaze were equally affected at the time of diagnosis in our patients.
PubMed: 1629370
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pubmed:1629370Le document en format XML
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<author><name sortKey="Friedman, D I" sort="Friedman, D I" uniqKey="Friedman D" first="D" last="Friedman">D Friedman</name>
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<author><name sortKey="Jankovic, J" sort="Jankovic, J" uniqKey="Jankovic J" first="J" last="Jankovic">Joseph Jankovic</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Neuro-ophthalmic findings in progressive supranuclear palsy.</title>
<author><name sortKey="Friedman, D I" sort="Friedman, D I" uniqKey="Friedman D" first="D" last="Friedman">D Friedman</name>
<affiliation><nlm:affiliation>Department of Neurology, SUNY Health Science Center, Syracuse 13201.</nlm:affiliation>
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<author><name sortKey="Jankovic, J" sort="Jankovic, J" uniqKey="Jankovic J" first="J" last="Jankovic">Joseph Jankovic</name>
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<series><title level="j">Journal of clinical neuro-ophthalmology</title>
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<imprint><date when="1992" type="published">1992</date>
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<term>Diagnosis, Differential</term>
<term>Eye Diseases (diagnosis)</term>
<term>Eye Diseases (physiopathology)</term>
<term>Eye Movements</term>
<term>Eyelid Diseases (diagnosis)</term>
<term>Eyelid Diseases (physiopathology)</term>
<term>Female</term>
<term>Fixation, Ocular</term>
<term>Humans</term>
<term>Male</term>
<term>Ocular Motility Disorders (physiopathology)</term>
<term>Parkinson Disease (diagnosis)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Supranuclear Palsy, Progressive (physiopathology)</term>
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<term>Parkinson Disease</term>
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<term>Eyelid Diseases</term>
<term>Ocular Motility Disorders</term>
<term>Parkinson Disease</term>
<term>Supranuclear Palsy, Progressive</term>
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<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Diagnosis, Differential</term>
<term>Eye Movements</term>
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<term>Humans</term>
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<front><div type="abstract" xml:lang="en">We studied 104 patients with progressive supranuclear palsy (PSP), 38 of whom were examined by both a neurologist and a neuro-ophthalmologist. Neuro-ophthalmic findings that may help differentiate PSP from Parkinson's disease include vertical supranuclear ophthalmoparesis and fixation instability. Eyelid abnormalities, particularly lid retraction, blepharospasm, and "apraxia" of eyelid opening and closure, were important distinguishing signs. Although downgaze palsy is felt to be the clinical hallmark of PSP, upgaze and downgaze were equally affected at the time of diagnosis in our patients.</div>
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