Searching for a relationship between manganese and welding and Parkinson's disease.
Identifieur interne : 001024 ( Main/Exploration ); précédent : 001023; suivant : 001025Searching for a relationship between manganese and welding and Parkinson's disease.
Auteurs : Joseph Jankovic [États-Unis]Source :
- Neurology ; 2005.
English descriptors
- KwdEn :
- Age of Onset, Brain (pathology), Brain (physiopathology), Cohort Studies, Cross-Sectional Studies, Disease Progression, Humans, Manganese (adverse effects), Manganese (metabolism), Manganese Poisoning (complications), Manganese Poisoning (physiopathology), Occupational Exposure (adverse effects), Parkinson Disease (etiology), Parkinson Disease (physiopathology), Risk Factors, Welding (statistics & numerical data).
- MESH :
- chemical , adverse effects : Manganese.
- chemical , metabolism : Manganese.
- adverse effects : Occupational Exposure.
- complications : Manganese Poisoning.
- etiology : Parkinson Disease.
- pathology : Brain.
- physiopathology : Brain, Manganese Poisoning, Parkinson Disease.
- statistics & numerical data : Welding.
- Age of Onset, Cohort Studies, Cross-Sectional Studies, Disease Progression, Humans, Risk Factors.
Abstract
Research into the causes of Parkinson disease (PD) has accelerated recently with the discovery of novel gene mutations. The majority of PD cases, however, remain idiopathic and in those cases environmental causes should be considered. Several recent reports have focused on welding and manganese toxicity as potential risk factors for parkinsonism and some have even proposed that welding is a risk factor for PD. The controversy has stimulated this review, the primary aim of which is to critically and objectively examine the evidence or lack of evidence for a relationship among welding, manganese, parkinsonism, and PD.
DOI: 10.1212/01.WNL.0000166916.40902.63
PubMed: 15985567
Affiliations:
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Le document en format XML
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<wicri:regionArea>Department of Neurology, Baylor College of Medicine, Houston, TX 77030</wicri:regionArea>
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<affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, Baylor College of Medicine, Houston, TX 77030, USA. josephj@bcm.tmc.edu</nlm:affiliation>
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<series><title level="j">Neurology</title>
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<term>Brain (pathology)</term>
<term>Brain (physiopathology)</term>
<term>Cohort Studies</term>
<term>Cross-Sectional Studies</term>
<term>Disease Progression</term>
<term>Humans</term>
<term>Manganese (adverse effects)</term>
<term>Manganese (metabolism)</term>
<term>Manganese Poisoning (complications)</term>
<term>Manganese Poisoning (physiopathology)</term>
<term>Occupational Exposure (adverse effects)</term>
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<term>Parkinson Disease (physiopathology)</term>
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<front><div type="abstract" xml:lang="en">Research into the causes of Parkinson disease (PD) has accelerated recently with the discovery of novel gene mutations. The majority of PD cases, however, remain idiopathic and in those cases environmental causes should be considered. Several recent reports have focused on welding and manganese toxicity as potential risk factors for parkinsonism and some have even proposed that welding is a risk factor for PD. The controversy has stimulated this review, the primary aim of which is to critically and objectively examine the evidence or lack of evidence for a relationship among welding, manganese, parkinsonism, and PD.</div>
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