Serveur d'exploration autour de Joseph Jankovic

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

Relationship between neuropsychological outcome and DBS surgical trajectory and electrode location

Identifieur interne : 000B26 ( Main/Exploration ); précédent : 000B25; suivant : 000B27

Relationship between neuropsychological outcome and DBS surgical trajectory and electrode location

Auteurs : Michele York [États-Unis] ; Elisabeth Wilde [États-Unis] ; Richard Simpson [États-Unis] ; Joseph Jankovic [États-Unis]

Source :

RBID : Pascal:10-0021238

Descripteurs français

English descriptors

Abstract

Background: The outcome literature of subthalamic nuclei (STN) deep brain stimulation (DBS) suggests that cognitive declines are commonly reported following surgery. We hypothesized that differences in electrode position and surgical trajectory may lead to a differential neuropsychological outcome. Methods: We conducted a standardized evaluation of the location of the DBS electrode tip and the active electrodes, the surgical trajectory through which they were placed, and their relation to neuropsychological change scores (mental status, verbal memory, verbal fluency, and psychological measures) in 17 bilateral STN DBS patients using 6 month post-surgical magnetic resonance imaging data. Results: Declines in mental status scores were related to electrodes that were more posterior-laterally placed within the frontal quadrant in either hemisphere or those located superiorally in the left hemisphere. Electrodes that were closer to the approximated STN and more superiorally located in the left hemisphere were associated with verbal learning declines at 6 months following surgery. In the right hemisphere, the electrodes that were located more in the lateral direction were related to verbal short-term memory declines; while for verbal long-term memory declines were found for electrodes located more posterior-laterally in the left hemisphere. Declines in verbal fluency scores were more variable with associations found between change scores and electrodes in the lateral and superior directions in the left hemisphere and those electrodes closer to the approximated STN and more superiorally and posteriorally located in the right hemisphere. In contrast, semantic fluency declines were only related to right hemisphere electrodes located more superiorally. Declines in mood were related to those electrodes located further away from the approximated STN, particularly those located more inferiorally and laterally in the left hemisphere. Anxiety change scores were not associated with the location of the electrodes. Conclusions: The results provide preliminary evidence that 6 months following bilateral STN DBS cognitive and emotional changes may be related to the surgical trajectory and electrode placement.

Url:


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en" level="a">Relationship between neuropsychological outcome and DBS surgical trajectory and electrode location</title>
<author>
<name sortKey="York, Michele K" sort="York, Michele K" uniqKey="York M" first="Michele" last="York">Michele York</name>
<affiliation wicri:level="2">
<inist:fA14 i1="01">
<s1>Baylor College of Medicine, Department of Neurology-The Parkinson's Disease and Movement Disorders Clinic, The Michael E. Debakey Veterans Affairs Medical Center</s1>
<s2>Houston, Texas</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Texas</region>
</placeName>
</affiliation>
<affiliation wicri:level="2">
<inist:fA14 i1="03">
<s1>The Michael E. DeBakey Veterans Affairs Medical Center, Parkinson's Disease Research, Education, and Clinical Center</s1>
<s2>Houston, Texas</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Wilde, Elisabeth A" sort="Wilde, Elisabeth A" uniqKey="Wilde E" first="Elisabeth" last="Wilde">Elisabeth Wilde</name>
<affiliation wicri:level="2">
<inist:fA14 i1="02">
<s1>Baylor College of Medicine, Department of Physical Medicine and Rehabilitation</s1>
<s2>Houston, Texas</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Simpson, Richard" sort="Simpson, Richard" uniqKey="Simpson R" first="Richard" last="Simpson">Richard Simpson</name>
<affiliation wicri:level="2">
<inist:fA14 i1="04">
<s1>The Methodist Hospital Neurological Institute</s1>
<s2>Houston, Texas</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name>
<affiliation wicri:level="2">
<inist:fA14 i1="01">
<s1>Baylor College of Medicine, Department of Neurology-The Parkinson's Disease and Movement Disorders Clinic, The Michael E. Debakey Veterans Affairs Medical Center</s1>
<s2>Houston, Texas</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Texas</region>
</placeName>
<placeName>
<settlement type="city">Houston</settlement>
<region type="state">Texas</region>
</placeName>
<orgName type="university" n="3">Baylor College of Medicine</orgName>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">INIST</idno>
<idno type="inist">10-0021238</idno>
<date when="2009">2009</date>
<idno type="stanalyst">PASCAL 10-0021238 INIST</idno>
<idno type="RBID">Pascal:10-0021238</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000029</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000135</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000029</idno>
<idno type="wicri:doubleKey">0022-510X:2009:York M:relationship:between:neuropsychological</idno>
<idno type="wicri:Area/Main/Merge">000B38</idno>
<idno type="wicri:source">PMC</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783787</idno>
<idno type="RBID">PMC:2783787</idno>
<idno type="wicri:Area/Pmc/Corpus">000150</idno>
<idno type="wicri:Area/Pmc/Curation">000150</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000178</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">000108</idno>
<idno type="wicri:Area/PubMed/Curation">000108</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000109</idno>
<idno type="wicri:Area/Ncbi/Merge">000257</idno>
<idno type="wicri:Area/Ncbi/Curation">000257</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000257</idno>
<idno type="wicri:doubleKey">0022-510X:2009:York M:relationship:between:neuropsychological</idno>
<idno type="wicri:Area/Main/Merge">000838</idno>
<idno type="wicri:Area/Main/Curation">000B26</idno>
<idno type="wicri:Area/Main/Exploration">000B26</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title xml:lang="en" level="a">Relationship between neuropsychological outcome and DBS surgical trajectory and electrode location</title>
<author>
<name sortKey="York, Michele K" sort="York, Michele K" uniqKey="York M" first="Michele" last="York">Michele York</name>
<affiliation wicri:level="2">
<inist:fA14 i1="01">
<s1>Baylor College of Medicine, Department of Neurology-The Parkinson's Disease and Movement Disorders Clinic, The Michael E. Debakey Veterans Affairs Medical Center</s1>
<s2>Houston, Texas</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Texas</region>
</placeName>
</affiliation>
<affiliation wicri:level="2">
<inist:fA14 i1="03">
<s1>The Michael E. DeBakey Veterans Affairs Medical Center, Parkinson's Disease Research, Education, and Clinical Center</s1>
<s2>Houston, Texas</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Wilde, Elisabeth A" sort="Wilde, Elisabeth A" uniqKey="Wilde E" first="Elisabeth" last="Wilde">Elisabeth Wilde</name>
<affiliation wicri:level="2">
<inist:fA14 i1="02">
<s1>Baylor College of Medicine, Department of Physical Medicine and Rehabilitation</s1>
<s2>Houston, Texas</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Simpson, Richard" sort="Simpson, Richard" uniqKey="Simpson R" first="Richard" last="Simpson">Richard Simpson</name>
<affiliation wicri:level="2">
<inist:fA14 i1="04">
<s1>The Methodist Hospital Neurological Institute</s1>
<s2>Houston, Texas</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name>
<affiliation wicri:level="2">
<inist:fA14 i1="01">
<s1>Baylor College of Medicine, Department of Neurology-The Parkinson's Disease and Movement Disorders Clinic, The Michael E. Debakey Veterans Affairs Medical Center</s1>
<s2>Houston, Texas</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">Texas</region>
</placeName>
<placeName>
<settlement type="city">Houston</settlement>
<region type="state">Texas</region>
</placeName>
<orgName type="university" n="3">Baylor College of Medicine</orgName>
</affiliation>
</author>
</analytic>
<series>
<title level="j" type="main">Journal of the neurological sciences</title>
<title level="j" type="abbreviated">J. neurol. sci.</title>
<idno type="ISSN">0022-510X</idno>
<imprint>
<date when="2009">2009</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt>
<title level="j" type="main">Journal of the neurological sciences</title>
<title level="j" type="abbreviated">J. neurol. sci.</title>
<idno type="ISSN">0022-510X</idno>
</seriesStmt>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Aged</term>
<term>Brain (anatomy & histology)</term>
<term>Brain (physiopathology)</term>
<term>Brain (surgery)</term>
<term>Cognition</term>
<term>Cognition Disorders (etiology)</term>
<term>Cognition Disorders (physiopathology)</term>
<term>Cognition Disorders (prevention & control)</term>
<term>Deep Brain Stimulation (adverse effects)</term>
<term>Deep Brain Stimulation (instrumentation)</term>
<term>Deep Brain Stimulation (methods)</term>
<term>Deep brain stimulation</term>
<term>Disability Evaluation</term>
<term>Dominance, Cerebral (physiology)</term>
<term>Electrodes</term>
<term>Electrodes, Implanted (adverse effects)</term>
<term>Electrodes, Implanted (standards)</term>
<term>Female</term>
<term>Functional Laterality (physiology)</term>
<term>Humans</term>
<term>Language Disorders (etiology)</term>
<term>Language Disorders (physiopathology)</term>
<term>Language Disorders (prevention & control)</term>
<term>Male</term>
<term>Memory Disorders (etiology)</term>
<term>Memory Disorders (physiopathology)</term>
<term>Memory Disorders (prevention & control)</term>
<term>Memory, Short-Term (physiology)</term>
<term>Middle Aged</term>
<term>Mood Disorders (etiology)</term>
<term>Mood Disorders (physiopathology)</term>
<term>Mood Disorders (prevention & control)</term>
<term>Nervous system diseases</term>
<term>Neuropsychological Tests</term>
<term>Nuclear magnetic resonance imaging</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson Disease (surgery)</term>
<term>Parkinson disease</term>
<term>Postoperative Complications (etiology)</term>
<term>Postoperative Complications (physiopathology)</term>
<term>Postoperative Complications (prevention & control)</term>
<term>Prognosis</term>
<term>Surgery</term>
<term>Trajectory</term>
<term>Verbal Behavior (physiology)</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en">
<term>Deep Brain Stimulation</term>
<term>Electrodes, Implanted</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomy & histology" xml:lang="en">
<term>Brain</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Cognition Disorders</term>
<term>Language Disorders</term>
<term>Memory Disorders</term>
<term>Mood Disorders</term>
<term>Postoperative Complications</term>
</keywords>
<keywords scheme="MESH" qualifier="instrumentation" xml:lang="en">
<term>Deep Brain Stimulation</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Deep Brain Stimulation</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en">
<term>Dominance, Cerebral</term>
<term>Functional Laterality</term>
<term>Memory, Short-Term</term>
<term>Verbal Behavior</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en">
<term>Brain</term>
<term>Cognition Disorders</term>
<term>Language Disorders</term>
<term>Memory Disorders</term>
<term>Mood Disorders</term>
<term>Parkinson Disease</term>
<term>Postoperative Complications</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en">
<term>Cognition Disorders</term>
<term>Language Disorders</term>
<term>Memory Disorders</term>
<term>Mood Disorders</term>
<term>Postoperative Complications</term>
</keywords>
<keywords scheme="MESH" qualifier="standards" xml:lang="en">
<term>Electrodes, Implanted</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Brain</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Aged</term>
<term>Disability Evaluation</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr">
<term>Maladie de Parkinson</term>
<term>Pathologie du système nerveux</term>
<term>Pronostic</term>
<term>Chirurgie</term>
<term>Trajectoire</term>
<term>Electrode</term>
<term>Cognition</term>
<term>Imagerie RMN</term>
<term>Stimulation cérébrale profonde</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr">
<term>Chirurgie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Background: The outcome literature of subthalamic nuclei (STN) deep brain stimulation (DBS) suggests that cognitive declines are commonly reported following surgery. We hypothesized that differences in electrode position and surgical trajectory may lead to a differential neuropsychological outcome. Methods: We conducted a standardized evaluation of the location of the DBS electrode tip and the active electrodes, the surgical trajectory through which they were placed, and their relation to neuropsychological change scores (mental status, verbal memory, verbal fluency, and psychological measures) in 17 bilateral STN DBS patients using 6 month post-surgical magnetic resonance imaging data. Results: Declines in mental status scores were related to electrodes that were more posterior-laterally placed within the frontal quadrant in either hemisphere or those located superiorally in the left hemisphere. Electrodes that were closer to the approximated STN and more superiorally located in the left hemisphere were associated with verbal learning declines at 6 months following surgery. In the right hemisphere, the electrodes that were located more in the lateral direction were related to verbal short-term memory declines; while for verbal long-term memory declines were found for electrodes located more posterior-laterally in the left hemisphere. Declines in verbal fluency scores were more variable with associations found between change scores and electrodes in the lateral and superior directions in the left hemisphere and those electrodes closer to the approximated STN and more superiorally and posteriorally located in the right hemisphere. In contrast, semantic fluency declines were only related to right hemisphere electrodes located more superiorally. Declines in mood were related to those electrodes located further away from the approximated STN, particularly those located more inferiorally and laterally in the left hemisphere. Anxiety change scores were not associated with the location of the electrodes. Conclusions: The results provide preliminary evidence that 6 months following bilateral STN DBS cognitive and emotional changes may be related to the surgical trajectory and electrode placement.</div>
</front>
</TEI>
<affiliations>
<list>
<country>
<li>États-Unis</li>
</country>
<region>
<li>Texas</li>
</region>
<settlement>
<li>Houston</li>
</settlement>
<orgName>
<li>Baylor College of Medicine</li>
</orgName>
</list>
<tree>
<country name="États-Unis">
<region name="Texas">
<name sortKey="York, Michele K" sort="York, Michele K" uniqKey="York M" first="Michele" last="York">Michele York</name>
</region>
<name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name>
<name sortKey="Simpson, Richard" sort="Simpson, Richard" uniqKey="Simpson R" first="Richard" last="Simpson">Richard Simpson</name>
<name sortKey="Wilde, Elisabeth A" sort="Wilde, Elisabeth A" uniqKey="Wilde E" first="Elisabeth" last="Wilde">Elisabeth Wilde</name>
<name sortKey="York, Michele K" sort="York, Michele K" uniqKey="York M" first="Michele" last="York">Michele York</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/JankovicV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000B26 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000B26 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Santé
   |area=    JankovicV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Pascal:10-0021238
   |texte=   Relationship between neuropsychological outcome and DBS surgical trajectory and electrode location
}}

Wicri

This area was generated with Dilib version V0.6.19.
Data generation: Wed Feb 10 22:03:07 2016. Site generation: Tue Feb 13 16:14:27 2024