Botulinum toxin in the treatment of tremors, dystonias, sialorrhea and other symptoms associated with Parkinson's disease.
Identifieur interne : 000D49 ( Main/Exploration ); précédent : 000D48; suivant : 000D50Botulinum toxin in the treatment of tremors, dystonias, sialorrhea and other symptoms associated with Parkinson's disease.
Auteurs : James. Sheffield [États-Unis] ; Joseph Jankovic [États-Unis]Source :
- Expert review of neurotherapeutics ; 2007.
English descriptors
- KwdEn :
- Antidepressive Agents, Second-Generation (administration & dosage), Botulinum Toxins (administration & dosage), Clinical Trials as Topic (trends), Dose-Response Relationship, Drug, Dystonia (drug therapy), Dystonia (etiology), Humans, Parkinson Disease (complications), Parkinson Disease (drug therapy), Practice Patterns, Physicians' (trends), Sialorrhea (drug therapy), Sialorrhea (etiology), Treatment Outcome, Tremor (drug therapy), Tremor (etiology).
- MESH :
- chemical , administration & dosage : Antidepressive Agents, Second-Generation, Botulinum Toxins.
- complications : Parkinson Disease.
- drug therapy : Dystonia, Parkinson Disease, Sialorrhea, Tremor.
- etiology : Dystonia, Sialorrhea, Tremor.
- trends : Clinical Trials as Topic, Practice Patterns, Physicians'.
- Dose-Response Relationship, Drug, Humans, Treatment Outcome.
Abstract
Botulinum toxins are an effective treatment modality for a growing number of neurologic conditions. Although there has been varied interest and success in their use, they have been studied for a variety of conditions associated with Parkinson's disease. Conditions reviewed in this paper include hand and jaw tremor, dystonia, blepharospasm and apraxia of eyelid opening, bruxism, camptocormia, freezing of gait, sialorrhea and constipation. We will make comments when applicable on our unique experience with botulinum toxin in these conditions. Other conditions associated with Parkinson's disease, which will not be reviewed here, but may benefit from botulinum toxin treatment include anterocollis (also known as dropped head syndrome), hyperhidrosis, seborrhea and overactive bladder.
DOI: 10.1586/14737175.7.6.637
PubMed: 17563247
Affiliations:
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Le document en format XML
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<author><name sortKey="Sheffield, James K" sort="Sheffield, James K" uniqKey="Sheffield J" first="James" last="Sheffield">James. Sheffield</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, Baylor College of Medicine, Parkinson's Disease Center & Movement Disorders Clinic, 6550 Fannin, Suite 1801, Houston, TX 77030, USA. jksheffi@bcm.edu</nlm:affiliation>
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<wicri:regionArea>Department of Neurology, Baylor College of Medicine, Parkinson's Disease Center & Movement Disorders Clinic, 6550 Fannin, Suite 1801, Houston, TX 77030</wicri:regionArea>
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<author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name>
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<term>Dose-Response Relationship, Drug</term>
<term>Dystonia (drug therapy)</term>
<term>Dystonia (etiology)</term>
<term>Humans</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Practice Patterns, Physicians' (trends)</term>
<term>Sialorrhea (drug therapy)</term>
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<term>Treatment Outcome</term>
<term>Tremor (drug therapy)</term>
<term>Tremor (etiology)</term>
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<front><div type="abstract" xml:lang="en">Botulinum toxins are an effective treatment modality for a growing number of neurologic conditions. Although there has been varied interest and success in their use, they have been studied for a variety of conditions associated with Parkinson's disease. Conditions reviewed in this paper include hand and jaw tremor, dystonia, blepharospasm and apraxia of eyelid opening, bruxism, camptocormia, freezing of gait, sialorrhea and constipation. We will make comments when applicable on our unique experience with botulinum toxin in these conditions. Other conditions associated with Parkinson's disease, which will not be reviewed here, but may benefit from botulinum toxin treatment include anterocollis (also known as dropped head syndrome), hyperhidrosis, seborrhea and overactive bladder.</div>
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