Treatment of camptocormia with botulinum toxin.
Identifieur interne : 000008 ( Main/Exploration ); précédent : 000007; suivant : 000009Treatment of camptocormia with botulinum toxin.
Auteurs : Kelly. Bertram [Australie] ; Paola Stirpe [Italie] ; Carlo Colosimo [Italie]Source :
- Toxicon : official journal of the International Society on Toxinology ; 2015.
Abstract
Camptocormia is defined as an involuntary axial postural distortion of >45° flexion which occurs in the upright position, increases whilst walking and resolves when supine (Ashour and Jankovic, 2006). Unlike orthopaedic or age related kyphosis it is not a fixed structural deformity and produces kyphosis at predominantly lumbar and thoracic rather than cervical regions. Camptocormia has been reported due to a wide range of neurologic, psychiatric, muscular and orthopaedic conditions as well as rare reports of its emergence following the initiation of a number of medications (Finsterer and Strobl, 2010). Parkinson's disease (PD) includes prominent motor features of bradykinesia, rigidity and reduced postural balance responses in all those affected with this disease, but can also cause a range of other motor and non-motor features. Camptocormia is reported in a minority of patients with PD, and it is usually associated with longer disease duration and greater disease burden (Tiple et al., 2009). The aetiology of camptocormia in PD is debated, and responses to treatment have been generally poor and variable between studies. Recent studies have suggested the use of botulinum toxin may improve posture in some affected individuals.
DOI: 10.1016/j.toxicon.2015.06.004
PubMed: 26079953
Affiliations:
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Bertram</name><affiliation wicri:level="1"><nlm:affiliation>Neurosciences, Alfred Hospital, Melbourne, Victoria, Australia; Faculty of Medicine Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neurosciences, Alfred Hospital, Melbourne, Victoria, Australia; Faculty of Medicine Nursing and Health Sciences, Monash University, Melbourne, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Stirpe, Paola" sort="Stirpe, Paola" uniqKey="Stirpe P" first="Paola" last="Stirpe">Paola Stirpe</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology and Psychiatry, Sapienza University of Rome, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Colosimo, Carlo" sort="Colosimo, Carlo" uniqKey="Colosimo C" first="Carlo" last="Colosimo">Carlo Colosimo</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy. 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Electronic address: carlo.colosimo@uniroma1.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology and Psychiatry, Sapienza University of Rome, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author></analytic><series><title level="j">Toxicon : official journal of the International Society on Toxinology</title><idno type="e-ISSN">1879-3150</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Camptocormia is defined as an involuntary axial postural distortion of >45° flexion which occurs in the upright position, increases whilst walking and resolves when supine (Ashour and Jankovic, 2006). Unlike orthopaedic or age related kyphosis it is not a fixed structural deformity and produces kyphosis at predominantly lumbar and thoracic rather than cervical regions. Camptocormia has been reported due to a wide range of neurologic, psychiatric, muscular and orthopaedic conditions as well as rare reports of its emergence following the initiation of a number of medications (Finsterer and Strobl, 2010). Parkinson's disease (PD) includes prominent motor features of bradykinesia, rigidity and reduced postural balance responses in all those affected with this disease, but can also cause a range of other motor and non-motor features. Camptocormia is reported in a minority of patients with PD, and it is usually associated with longer disease duration and greater disease burden (Tiple et al., 2009). The aetiology of camptocormia in PD is debated, and responses to treatment have been generally poor and variable between studies. Recent studies have suggested the use of botulinum toxin may improve posture in some affected individuals.</div></front></TEI><affiliations><list><country><li>Australie</li><li>Italie</li></country><region><li>Latium</li></region><settlement><li>Rome</li></settlement></list><tree><country name="Australie"><noRegion><name sortKey="Bertram, Kelly L" sort="Bertram, Kelly L" uniqKey="Bertram K" first="Kelly" last="Bertram">Kelly. Bertram</name></noRegion></country><country name="Italie"><region name="Latium"><name sortKey="Stirpe, Paola" sort="Stirpe, Paola" uniqKey="Stirpe P" first="Paola" last="Stirpe">Paola Stirpe</name></region><name sortKey="Colosimo, Carlo" sort="Colosimo, Carlo" uniqKey="Colosimo C" first="Carlo" last="Colosimo">Carlo Colosimo</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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