Nucleoprotein and membrane protein genes are associated with restriction of replication of influenza A/Mallard/NY/78 virus and its reassortants in squirrel monkey respiratory tract.
Identifieur interne : 000506 ( PubMed/Curation ); précédent : 000505; suivant : 000507Nucleoprotein and membrane protein genes are associated with restriction of replication of influenza A/Mallard/NY/78 virus and its reassortants in squirrel monkey respiratory tract.
Auteurs : S F Tian ; A J Buckler-White ; W T London ; L J Reck ; R M Chanock ; B R MurphySource :
- Journal of virology [ 0022-538X ] ; 1985.
Descripteurs français
- KwdFr :
- ARN viral (analyse), Animaux, Gènes viraux, Humains, Nucléoprotéines (génétique), Oiseaux (microbiologie), Protéines de la matrice virale, Protéines virales (génétique), Réplication virale, Saimiri (microbiologie), Température élevée, Trachée (microbiologie), Virus de la grippe A (génétique), Virus de la grippe A (physiologie).
- MESH :
- analyse : ARN viral.
- génétique : Nucléoprotéines, Protéines virales, Virus de la grippe A.
- microbiologie : Oiseaux, Saimiri, Trachée.
- physiologie : Virus de la grippe A.
- Animaux, Gènes viraux, Humains, Protéines de la matrice virale, Réplication virale, Température élevée.
English descriptors
- KwdEn :
- MESH :
- chemical , analysis : RNA, Viral.
- chemical , genetics : Nucleoproteins, Viral Proteins.
- genetics : Influenza A virus.
- microbiology : Birds, Saimiri, Trachea.
- physiology : Influenza A virus.
- Animals, Genes, Viral, Hot Temperature, Humans, Viral Matrix Proteins, Virus Replication.
Abstract
An avian influenza A virus, A/Mallard/NY/6750/78(H2N2), was restricted in in replication in the respiratory tract of squirrel monkeys. Avian-human influenza A reassortant viruses possessing the six RNA segments coding for nonsurface proteins (i.e., internal genes) of this avian virus were as restricted in replication in squirrel monkeys as their avian influenza parent. These findings indicated that restriction of replication of the avian influenza virus is a function of one or more of its internal genes. For an investigation of which of the avian influenza genes was responsible for restricted replication in the respiratory tract of primates, reassortant viruses were produced that contained human influenza virus surface antigens from the A/Udorn/72(H3N2) virus and one or more of the internal genes derived from the avian influenza virus parent. Avian-human reassortant influenza A viruses containing only the nucleoprotein or matrix protein RNA segment from the avian influenza virus parent were as restricted in their growth as an avian-human influenza reassortant virus containing each of the six avian influenza internal genes. In addition, an avian-human influenza reassortant virus possessing only the avian RNA 1 and nonstructural genes (which by themselves do not specify restricted replication) manifested a significant reduction of virus replication in squirrel monkey tracheas. Thus, the avian nucleoprotein and matrix genes appear to play a major role in the host range restriction exhibited by the A/Mallard/78 virus and its reassortants, but the combination of RNA 1 and nonstructural genes also contributes to restriction of replication.
PubMed: 3973966
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Nucleoprotein and membrane protein genes are associated with restriction of replication of influenza A/Mallard/NY/78 virus and its reassortants in squirrel monkey respiratory tract.</title><author><name sortKey="Tian, S F" sort="Tian, S F" uniqKey="Tian S" first="S F" last="Tian">S F Tian</name></author><author><name sortKey="Buckler White, A J" sort="Buckler White, A J" uniqKey="Buckler White A" first="A J" last="Buckler-White">A J Buckler-White</name></author><author><name sortKey="London, W T" sort="London, W T" uniqKey="London W" first="W T" last="London">W T London</name></author><author><name sortKey="Reck, L J" sort="Reck, L J" uniqKey="Reck L" first="L J" last="Reck">L J Reck</name></author><author><name sortKey="Chanock, R M" sort="Chanock, R M" uniqKey="Chanock R" first="R M" last="Chanock">R M Chanock</name></author><author><name sortKey="Murphy, B R" sort="Murphy, B R" uniqKey="Murphy B" first="B R" last="Murphy">B R Murphy</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1985">1985</date><idno type="RBID">pubmed:3973966</idno><idno type="pmid">3973966</idno><idno type="wicri:Area/PubMed/Corpus">000506</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000506</idno><idno type="wicri:Area/PubMed/Curation">000506</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000506</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Nucleoprotein and membrane protein genes are associated with restriction of replication of influenza A/Mallard/NY/78 virus and its reassortants in squirrel monkey respiratory tract.</title><author><name sortKey="Tian, S F" sort="Tian, S F" uniqKey="Tian S" first="S F" last="Tian">S F Tian</name></author><author><name sortKey="Buckler White, A J" sort="Buckler White, A J" uniqKey="Buckler White A" first="A J" last="Buckler-White">A J Buckler-White</name></author><author><name sortKey="London, W T" sort="London, W T" uniqKey="London W" first="W T" last="London">W T London</name></author><author><name sortKey="Reck, L J" sort="Reck, L J" uniqKey="Reck L" first="L J" last="Reck">L J Reck</name></author><author><name sortKey="Chanock, R M" sort="Chanock, R M" uniqKey="Chanock R" first="R M" last="Chanock">R M Chanock</name></author><author><name sortKey="Murphy, B R" sort="Murphy, B R" uniqKey="Murphy B" first="B R" last="Murphy">B R Murphy</name></author></analytic><series><title level="j">Journal of virology</title><idno type="ISSN">0022-538X</idno><imprint><date when="1985" type="published">1985</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Birds (microbiology)</term><term>Genes, Viral</term><term>Hot Temperature</term><term>Humans</term><term>Influenza A virus (genetics)</term><term>Influenza A virus (physiology)</term><term>Nucleoproteins (genetics)</term><term>RNA, Viral (analysis)</term><term>Saimiri (microbiology)</term><term>Trachea (microbiology)</term><term>Viral Matrix Proteins</term><term>Viral Proteins (genetics)</term><term>Virus Replication</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN viral (analyse)</term><term>Animaux</term><term>Gènes viraux</term><term>Humains</term><term>Nucléoprotéines (génétique)</term><term>Oiseaux (microbiologie)</term><term>Protéines de la matrice virale</term><term>Protéines virales (génétique)</term><term>Réplication virale</term><term>Saimiri (microbiologie)</term><term>Température élevée</term><term>Trachée (microbiologie)</term><term>Virus de la grippe A (génétique)</term><term>Virus de la grippe A (physiologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>RNA, Viral</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Nucleoproteins</term><term>Viral Proteins</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>ARN viral</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Influenza A virus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Nucléoprotéines</term><term>Protéines virales</term><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Oiseaux</term><term>Saimiri</term><term>Trachée</term></keywords><keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Birds</term><term>Saimiri</term><term>Trachea</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Influenza A virus</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Genes, Viral</term><term>Hot Temperature</term><term>Humans</term><term>Viral Matrix Proteins</term><term>Virus Replication</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Gènes viraux</term><term>Humains</term><term>Protéines de la matrice virale</term><term>Réplication virale</term><term>Température élevée</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">An avian influenza A virus, A/Mallard/NY/6750/78(H2N2), was restricted in in replication in the respiratory tract of squirrel monkeys. Avian-human influenza A reassortant viruses possessing the six RNA segments coding for nonsurface proteins (i.e., internal genes) of this avian virus were as restricted in replication in squirrel monkeys as their avian influenza parent. These findings indicated that restriction of replication of the avian influenza virus is a function of one or more of its internal genes. For an investigation of which of the avian influenza genes was responsible for restricted replication in the respiratory tract of primates, reassortant viruses were produced that contained human influenza virus surface antigens from the A/Udorn/72(H3N2) virus and one or more of the internal genes derived from the avian influenza virus parent. Avian-human reassortant influenza A viruses containing only the nucleoprotein or matrix protein RNA segment from the avian influenza virus parent were as restricted in their growth as an avian-human influenza reassortant virus containing each of the six avian influenza internal genes. In addition, an avian-human influenza reassortant virus possessing only the avian RNA 1 and nonstructural genes (which by themselves do not specify restricted replication) manifested a significant reduction of virus replication in squirrel monkey tracheas. Thus, the avian nucleoprotein and matrix genes appear to play a major role in the host range restriction exhibited by the A/Mallard/78 virus and its reassortants, but the combination of RNA 1 and nonstructural genes also contributes to restriction of replication.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">3973966</PMID><DateCompleted><Year>1985</Year><Month>04</Month><Day>03</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0022-538X</ISSN><JournalIssue CitedMedium="Print"><Volume>53</Volume><Issue>3</Issue><PubDate><Year>1985</Year><Month>Mar</Month></PubDate></JournalIssue><Title>Journal of virology</Title><ISOAbbreviation>J. Virol.</ISOAbbreviation></Journal><ArticleTitle>Nucleoprotein and membrane protein genes are associated with restriction of replication of influenza A/Mallard/NY/78 virus and its reassortants in squirrel monkey respiratory tract.</ArticleTitle><Pagination><MedlinePgn>771-5</MedlinePgn></Pagination><Abstract><AbstractText>An avian influenza A virus, A/Mallard/NY/6750/78(H2N2), was restricted in in replication in the respiratory tract of squirrel monkeys. Avian-human influenza A reassortant viruses possessing the six RNA segments coding for nonsurface proteins (i.e., internal genes) of this avian virus were as restricted in replication in squirrel monkeys as their avian influenza parent. These findings indicated that restriction of replication of the avian influenza virus is a function of one or more of its internal genes. For an investigation of which of the avian influenza genes was responsible for restricted replication in the respiratory tract of primates, reassortant viruses were produced that contained human influenza virus surface antigens from the A/Udorn/72(H3N2) virus and one or more of the internal genes derived from the avian influenza virus parent. Avian-human reassortant influenza A viruses containing only the nucleoprotein or matrix protein RNA segment from the avian influenza virus parent were as restricted in their growth as an avian-human influenza reassortant virus containing each of the six avian influenza internal genes. In addition, an avian-human influenza reassortant virus possessing only the avian RNA 1 and nonstructural genes (which by themselves do not specify restricted replication) manifested a significant reduction of virus replication in squirrel monkey tracheas. Thus, the avian nucleoprotein and matrix genes appear to play a major role in the host range restriction exhibited by the A/Mallard/78 virus and its reassortants, but the combination of RNA 1 and nonstructural genes also contributes to restriction of replication.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tian</LastName><ForeName>S F</ForeName><Initials>SF</Initials></Author><Author ValidYN="Y"><LastName>Buckler-White</LastName><ForeName>A J</ForeName><Initials>AJ</Initials></Author><Author ValidYN="Y"><LastName>London</LastName><ForeName>W T</ForeName><Initials>WT</Initials></Author><Author ValidYN="Y"><LastName>Reck</LastName><ForeName>L J</ForeName><Initials>LJ</Initials></Author><Author ValidYN="Y"><LastName>Chanock</LastName><ForeName>R M</ForeName><Initials>RM</Initials></Author><Author ValidYN="Y"><LastName>Murphy</LastName><ForeName>B R</ForeName><Initials>BR</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Virol</MedlineTA><NlmUniqueID>0113724</NlmUniqueID><ISSNLinking>0022-538X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D009698">Nucleoproteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012367">RNA, Viral</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014763">Viral Matrix Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014764">Viral Proteins</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001717" MajorTopicYN="N">Birds</DescriptorName><QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005814" MajorTopicYN="Y">Genes, Viral</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006358" MajorTopicYN="N">Hot Temperature</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009980" MajorTopicYN="N">Influenza A virus</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009698" MajorTopicYN="N">Nucleoproteins</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012367" MajorTopicYN="N">RNA, Viral</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012453" MajorTopicYN="N">Saimiri</DescriptorName><QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014132" MajorTopicYN="N">Trachea</DescriptorName><QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014763" MajorTopicYN="N">Viral Matrix Proteins</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014764" MajorTopicYN="N">Viral Proteins</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014779" MajorTopicYN="Y">Virus Replication</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1985</Year><Month>3</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1985</Year><Month>3</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1985</Year><Month>3</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">3973966</ArticleId><ArticleId IdType="pmc">PMC254705</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Virology. 1976 Oct 15;74(2):332-44</Citation><ArticleIdList><ArticleId IdType="pubmed">982830</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 1980 Feb;101(1):242-9</Citation><ArticleIdList><ArticleId IdType="pubmed">7355577</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 1978 Jun 1;87(1):13-20</Citation><ArticleIdList><ArticleId IdType="pubmed">664248</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 1980 Apr 15;102(1):13-20</Citation><ArticleIdList><ArticleId IdType="pubmed">7368565</ArticleId></ArticleIdList></Reference><Reference><Citation>Infect Immun. 1980 Jun;28(3):688-91</Citation><ArticleIdList><ArticleId IdType="pubmed">6772565</ArticleId></ArticleIdList></Reference><Reference><Citation>Rev Infect Dis. 1980 May-Jun;2(3):421-32</Citation><ArticleIdList><ArticleId IdType="pubmed">6997969</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 1981 Jul 30;112(2):729-37</Citation><ArticleIdList><ArticleId IdType="pubmed">7257188</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 1981 Aug;113(1):397-402</Citation><ArticleIdList><ArticleId IdType="pubmed">6927848</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 1981 Jul;78(7):4170-4</Citation><ArticleIdList><ArticleId IdType="pubmed">6945577</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 1981 Oct 30;114(2):423-8</Citation><ArticleIdList><ArticleId IdType="pubmed">7292985</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biochem Biophys Methods. 1981 Oct;5(4):219-28</Citation><ArticleIdList><ArticleId IdType="pubmed">6171588</ArticleId></ArticleIdList></Reference><Reference><Citation>Infect Immun. 1982 May;36(2):645-50</Citation><ArticleIdList><ArticleId IdType="pubmed">7085075</ArticleId></ArticleIdList></Reference><Reference><Citation>Infect Immun. 1982 Sep;37(3):1119-26</Citation><ArticleIdList><ArticleId IdType="pubmed">7129631</ArticleId></ArticleIdList></Reference><Reference><Citation>J Gen Virol. 1982 Jan;58 Pt 1:211-5</Citation><ArticleIdList><ArticleId IdType="pubmed">6292344</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 1982 Dec 24;218(4579):1330-2</Citation><ArticleIdList><ArticleId IdType="pubmed">6183749</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 1984 Mar;133(2):438-42</Citation><ArticleIdList><ArticleId IdType="pubmed">6710867</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect Dis. 1984 Dec;150(6):841-50</Citation><ArticleIdList><ArticleId IdType="pubmed">6501928</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 1979 Jun;95(2):492-500</Citation><ArticleIdList><ArticleId IdType="pubmed">462800</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect Dis. 1976 Dec;134(6):585-94</Citation><ArticleIdList><ArticleId IdType="pubmed">1003014</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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