Immunogenicity of a synthetic peptide corresponding to a portion of the heavy chain of H3N2 influenza virus haemagglutinin.
Identifieur interne : 000484 ( PubMed/Curation ); précédent : 000483; suivant : 000485Immunogenicity of a synthetic peptide corresponding to a portion of the heavy chain of H3N2 influenza virus haemagglutinin.
Auteurs : E. Hamsíková ; H. Závadová ; M. Zaoral ; J. Jezek ; K. Bláha ; V. VonkaSource :
- The Journal of general virology [ 0022-1317 ] ; 1987.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- chemical , immunology : Hemagglutinins, Viral, Peptides.
- chemical : Antigen-Antibody Complex, Hemagglutinin Glycoproteins, Influenza Virus, Macromolecular Substances.
- immunology : Influenza A virus.
- Influenza A Virus, H3N2 Subtype, Radioimmunoassay.
Abstract
Rabbits were immunized with a synthetic octadecapeptide corresponding to the sequence ser-91 to leu-108 of the haemagglutinin heavy chain of H3N2 influenza A viruses. They developed antibodies reactive in solid-phase radioimmunoassay (SPRIA) with the peptide and with haemagglutinins of various H3N2 viruses but not of heterotypic H1N1 and H2N2 viruses. The antibodies were also non-reactive in the haemagglutination-inhibition or neutralization test. Influenza H3N2 virus replicated in the lungs of mice immunized with the peptide to the same extent as in the control mice. Of 27 human sera possessing anti-H3N2 activity or seven sera from rabbits immunized with either virions or haemagglutinins of various influenza A viruses, none was reactive with the peptide in SPRIA.
DOI: 10.1099/0022-1317-68-8-2249
PubMed: 3612090
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000484
Links to Exploration step
pubmed:3612090Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Immunogenicity of a synthetic peptide corresponding to a portion of the heavy chain of H3N2 influenza virus haemagglutinin.</title><author><name sortKey="Hamsikova, E" sort="Hamsikova, E" uniqKey="Hamsikova E" first="E" last="Hamsíková">E. Hamsíková</name></author><author><name sortKey="Zavadova, H" sort="Zavadova, H" uniqKey="Zavadova H" first="H" last="Závadová">H. Závadová</name></author><author><name sortKey="Zaoral, M" sort="Zaoral, M" uniqKey="Zaoral M" first="M" last="Zaoral">M. Zaoral</name></author><author><name sortKey="Jezek, J" sort="Jezek, J" uniqKey="Jezek J" first="J" last="Jezek">J. Jezek</name></author><author><name sortKey="Blaha, K" sort="Blaha, K" uniqKey="Blaha K" first="K" last="Bláha">K. Bláha</name></author><author><name sortKey="Vonka, V" sort="Vonka, V" uniqKey="Vonka V" first="V" last="Vonka">V. Vonka</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1987">1987</date><idno type="RBID">pubmed:3612090</idno><idno type="pmid">3612090</idno><idno type="doi">10.1099/0022-1317-68-8-2249</idno><idno type="wicri:Area/PubMed/Corpus">000484</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000484</idno><idno type="wicri:Area/PubMed/Curation">000484</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000484</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Immunogenicity of a synthetic peptide corresponding to a portion of the heavy chain of H3N2 influenza virus haemagglutinin.</title><author><name sortKey="Hamsikova, E" sort="Hamsikova, E" uniqKey="Hamsikova E" first="E" last="Hamsíková">E. Hamsíková</name></author><author><name sortKey="Zavadova, H" sort="Zavadova, H" uniqKey="Zavadova H" first="H" last="Závadová">H. Závadová</name></author><author><name sortKey="Zaoral, M" sort="Zaoral, M" uniqKey="Zaoral M" first="M" last="Zaoral">M. Zaoral</name></author><author><name sortKey="Jezek, J" sort="Jezek, J" uniqKey="Jezek J" first="J" last="Jezek">J. Jezek</name></author><author><name sortKey="Blaha, K" sort="Blaha, K" uniqKey="Blaha K" first="K" last="Bláha">K. Bláha</name></author><author><name sortKey="Vonka, V" sort="Vonka, V" uniqKey="Vonka V" first="V" last="Vonka">V. Vonka</name></author></analytic><series><title level="j">The Journal of general virology</title><idno type="ISSN">0022-1317</idno><imprint><date when="1987" type="published">1987</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antigen-Antibody Complex</term><term>Hemagglutinin Glycoproteins, Influenza Virus</term><term>Hemagglutinins, Viral (immunology)</term><term>Influenza A Virus, H3N2 Subtype</term><term>Influenza A virus (immunology)</term><term>Macromolecular Substances</term><term>Peptides (immunology)</term><term>Radioimmunoassay</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Complexe antigène-anticorps</term><term>Dosage radioimmunologique</term><term>Glycoprotéine hémagglutinine du virus influenza</term><term>Hémagglutinines virales (immunologie)</term><term>Peptides (immunologie)</term><term>Sous-type H3N2 du virus de la grippe A</term><term>Structures macromoléculaires</term><term>Virus de la grippe A (immunologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Hemagglutinins, Viral</term><term>Peptides</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Antigen-Antibody Complex</term><term>Hemagglutinin Glycoproteins, Influenza Virus</term><term>Macromolecular Substances</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Hémagglutinines virales</term><term>Peptides</term><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Influenza A virus</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Influenza A Virus, H3N2 Subtype</term><term>Radioimmunoassay</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Complexe antigène-anticorps</term><term>Dosage radioimmunologique</term><term>Glycoprotéine hémagglutinine du virus influenza</term><term>Sous-type H3N2 du virus de la grippe A</term><term>Structures macromoléculaires</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Rabbits were immunized with a synthetic octadecapeptide corresponding to the sequence ser-91 to leu-108 of the haemagglutinin heavy chain of H3N2 influenza A viruses. They developed antibodies reactive in solid-phase radioimmunoassay (SPRIA) with the peptide and with haemagglutinins of various H3N2 viruses but not of heterotypic H1N1 and H2N2 viruses. The antibodies were also non-reactive in the haemagglutination-inhibition or neutralization test. Influenza H3N2 virus replicated in the lungs of mice immunized with the peptide to the same extent as in the control mice. Of 27 human sera possessing anti-H3N2 activity or seven sera from rabbits immunized with either virions or haemagglutinins of various influenza A viruses, none was reactive with the peptide in SPRIA.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">3612090</PMID><DateCompleted><Year>1987</Year><Month>09</Month><Day>18</Day></DateCompleted><DateRevised><Year>2005</Year><Month>12</Month><Day>05</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0022-1317</ISSN><JournalIssue CitedMedium="Print"><Volume>68 ( Pt 8)</Volume><PubDate><Year>1987</Year><Month>Aug</Month></PubDate></JournalIssue><Title>The Journal of general virology</Title><ISOAbbreviation>J. Gen. Virol.</ISOAbbreviation></Journal><ArticleTitle>Immunogenicity of a synthetic peptide corresponding to a portion of the heavy chain of H3N2 influenza virus haemagglutinin.</ArticleTitle><Pagination><MedlinePgn>2249-52</MedlinePgn></Pagination><Abstract><AbstractText>Rabbits were immunized with a synthetic octadecapeptide corresponding to the sequence ser-91 to leu-108 of the haemagglutinin heavy chain of H3N2 influenza A viruses. They developed antibodies reactive in solid-phase radioimmunoassay (SPRIA) with the peptide and with haemagglutinins of various H3N2 viruses but not of heterotypic H1N1 and H2N2 viruses. The antibodies were also non-reactive in the haemagglutination-inhibition or neutralization test. Influenza H3N2 virus replicated in the lungs of mice immunized with the peptide to the same extent as in the control mice. Of 27 human sera possessing anti-H3N2 activity or seven sera from rabbits immunized with either virions or haemagglutinins of various influenza A viruses, none was reactive with the peptide in SPRIA.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Hamsíková</LastName><ForeName>E</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Závadová</LastName><ForeName>H</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Zaoral</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Jezek</LastName><ForeName>J</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Bláha</LastName><ForeName>K</ForeName><Initials>K</Initials></Author><Author ValidYN="Y"><LastName>Vonka</LastName><ForeName>V</ForeName><Initials>V</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Gen Virol</MedlineTA><NlmUniqueID>0077340</NlmUniqueID><ISSNLinking>0022-1317</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000936">Antigen-Antibody Complex</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D019267">Hemagglutinin Glycoproteins, Influenza Virus</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D006389">Hemagglutinins, Viral</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D046911">Macromolecular Substances</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010455">Peptides</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000936" MajorTopicYN="N">Antigen-Antibody Complex</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019267" MajorTopicYN="N">Hemagglutinin Glycoproteins, Influenza Virus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006389" MajorTopicYN="Y">Hemagglutinins, Viral</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D053122" MajorTopicYN="Y">Influenza A Virus, H3N2 Subtype</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009980" MajorTopicYN="N">Influenza A virus</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D046911" MajorTopicYN="N">Macromolecular Substances</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010455" MajorTopicYN="N">Peptides</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011863" MajorTopicYN="N">Radioimmunoassay</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1987</Year><Month>8</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1987</Year><Month>8</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1987</Year><Month>8</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">3612090</ArticleId><ArticleId IdType="doi">10.1099/0022-1317-68-8-2249</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000484 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 000484 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= PubMed
|étape= Curation
|type= RBID
|clé= pubmed:3612090
|texte= Immunogenicity of a synthetic peptide corresponding to a portion of the heavy chain of H3N2 influenza virus haemagglutinin.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:3612090" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \
| NlmPubMed2Wicri -a H2N2V1
| This area was generated with Dilib version V0.6.33. |  |