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Analysis of internal proteins of influenza A (H2N2) viruses isolated from birds in East Germany in 1983.

Identifieur interne : 000436 ( PubMed/Curation ); précédent : 000435; suivant : 000437

Analysis of internal proteins of influenza A (H2N2) viruses isolated from birds in East Germany in 1983.

Auteurs : J. Sch Fer [Allemagne] ; M L Khristova ; T L Busse ; R. Sinnecker ; I G Kharitonenkov ; C. Schrader ; J. Süss ; D. Bucher

Source :

RBID : pubmed:1279962

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English descriptors

Abstract

Proteins and RNAs of influenza A (H2N2) viruses isolated from birds in 1983 in East Germany were compared antigenically with those of H2N2 human strains. The electrophoretic mobility of the viral proteins and of the S1-treated double-stranded RNAs from two human and six avian strains, as well as the results of EIA-tests using monoclonal antibodies to their matrix protein and nucleoproteins indicate an antigenic relationship between the avian isolates and human strains of H2N2 subtype. One of the avian strains had a reduced amount of matrix protein.

PubMed: 1279962

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pubmed:1279962

Le document en format XML

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<nlm:affiliation>Institute for Viral Zoonoses, Potsdam, Germany.</nlm:affiliation>
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<name sortKey="Busse, T L" sort="Busse, T L" uniqKey="Busse T" first="T L" last="Busse">T L Busse</name>
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<term>Enzyme-Linked Immunosorbent Assay</term>
<term>Epitopes (analysis)</term>
<term>Germany, East</term>
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<div type="abstract" xml:lang="en">Proteins and RNAs of influenza A (H2N2) viruses isolated from birds in 1983 in East Germany were compared antigenically with those of H2N2 human strains. The electrophoretic mobility of the viral proteins and of the S1-treated double-stranded RNAs from two human and six avian strains, as well as the results of EIA-tests using monoclonal antibodies to their matrix protein and nucleoproteins indicate an antigenic relationship between the avian isolates and human strains of H2N2 subtype. One of the avian strains had a reduced amount of matrix protein.</div>
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