Memory T-cell immune response in healthy young adults vaccinated with live attenuated influenza A (H5N2) vaccine.
Identifieur interne : 000166 ( PubMed/Curation ); précédent : 000165; suivant : 000167Memory T-cell immune response in healthy young adults vaccinated with live attenuated influenza A (H5N2) vaccine.
Auteurs : T V Chirkova [Russie] ; A N Naykhin ; G D Petukhova ; D A Korenkov ; S A Donina ; A N Mironov ; L G RudenkoSource :
- Clinical and vaccine immunology : CVI [ 1556-679X ] ; 2011.
Descripteurs français
- KwdFr :
- Cytokines (biosynthèse), Humains, Jeune adulte, Lymphocytes T CD4+ (immunologie), Lymphocytes T CD8+ (immunologie), Mémoire immunologique, Rappel de vaccin (), Sous-type H2N2 du virus de la grippe A (génétique), Sous-type H2N2 du virus de la grippe A (immunologie), Sous-type H5N2 du virus de la grippe A (génétique), Sous-type H5N2 du virus de la grippe A (immunologie), Vaccination (), Vaccins antigrippaux (administration et posologie), Vaccins antigrippaux (immunologie), Vaccins atténués (administration et posologie), Vaccins atténués (immunologie), Virus recombinants (immunologie).
- MESH :
- administration et posologie : Vaccins antigrippaux, Vaccins atténués.
- biosynthèse : Cytokines.
- génétique : Sous-type H2N2 du virus de la grippe A, Sous-type H5N2 du virus de la grippe A.
- immunologie : Lymphocytes T CD4+, Lymphocytes T CD8+, Sous-type H2N2 du virus de la grippe A, Sous-type H5N2 du virus de la grippe A, Vaccins antigrippaux, Vaccins atténués, Virus recombinants.
- Humains, Jeune adulte, Mémoire immunologique, Rappel de vaccin, Vaccination.
English descriptors
- KwdEn :
- CD4-Positive T-Lymphocytes (immunology), CD8-Positive T-Lymphocytes (immunology), Cytokines (biosynthesis), Humans, Immunization, Secondary (methods), Immunologic Memory, Influenza A Virus, H2N2 Subtype (genetics), Influenza A Virus, H2N2 Subtype (immunology), Influenza A Virus, H5N2 Subtype (genetics), Influenza A Virus, H5N2 Subtype (immunology), Influenza Vaccines (administration & dosage), Influenza Vaccines (immunology), Reassortant Viruses (immunology), Vaccination (methods), Vaccines, Attenuated (administration & dosage), Vaccines, Attenuated (immunology), Young Adult.
- MESH :
- chemical , administration & dosage : Influenza Vaccines, Vaccines, Attenuated.
- chemical , biosynthesis : Cytokines.
- genetics : Influenza A Virus, H2N2 Subtype, Influenza A Virus, H5N2 Subtype.
- immunology : CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Influenza A Virus, H2N2 Subtype, Influenza A Virus, H5N2 Subtype, Influenza Vaccines, Reassortant Viruses, Vaccines, Attenuated.
- methods : Immunization, Secondary, Vaccination.
- Humans, Immunologic Memory, Young Adult.
Abstract
Cellular immune responses of both CD4 and CD8 memory/effector T cells were evaluated in healthy young adults who received two doses of live attenuated influenza A (H5N2) vaccine. The vaccine was developed by reassortment of nonpathogenic avian A/Duck/Potsdam/1402-6/68 (H5N2) and cold-adapted A/Leningrad/134/17/57 (H2N2) viruses. T-cell responses were measured by standard methods of intracellular cytokine staining of gamma interferon (IFN-γ)-producing cells and a novel T-cell recognition of antigen-presenting cells by protein capture (TRAP) assay based on the trogocytosis phenomenon, namely, plasma membrane exchange between interacting immune cells. TRAP enables the detection of activated trogocytosis-positive T cells after virus stimulation. We showed that two doses of live attenuated influenza A (H5N2) vaccine promoted both CD4 and CD8 T-memory-cell responses in peripheral blood of healthy young subjects in the clinical study. Significant differences in geometric mean titers (GMTs) of influenza A (H5N2)-specific IFN-γ(+) cells were observed at day 42 following the second vaccination, while peak levels of trogocytosis(+) T cells were detected earlier, on the 21st day after the second vaccination. The inverse correlation of baseline levels compared to postvaccine fold changes in GMTs of influenza-specific CD4 and CD8 T cells demonstrated that baseline levels of these specific cells could be considered a predictive factor of vaccine immunogenicity.
DOI: 10.1128/CVI.05116-11
PubMed: 21813657
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000166
Links to Exploration step
pubmed:21813657Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Memory T-cell immune response in healthy young adults vaccinated with live attenuated influenza A (H5N2) vaccine.</title><author><name sortKey="Chirkova, T V" sort="Chirkova, T V" uniqKey="Chirkova T" first="T V" last="Chirkova">T V Chirkova</name><affiliation wicri:level="1"><nlm:affiliation>Department of Virology, Institute of Experimental Medicine, Acad. Pavlov St. 12, Saint Petersburg 197376, Russia.</nlm:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>Department of Virology, Institute of Experimental Medicine, Acad. Pavlov St. 12, Saint Petersburg 197376</wicri:regionArea></affiliation></author><author><name sortKey="Naykhin, A N" sort="Naykhin, A N" uniqKey="Naykhin A" first="A N" last="Naykhin">A N Naykhin</name></author><author><name sortKey="Petukhova, G D" sort="Petukhova, G D" uniqKey="Petukhova G" first="G D" last="Petukhova">G D Petukhova</name></author><author><name sortKey="Korenkov, D A" sort="Korenkov, D A" uniqKey="Korenkov D" first="D A" last="Korenkov">D A Korenkov</name></author><author><name sortKey="Donina, S A" sort="Donina, S A" uniqKey="Donina S" first="S A" last="Donina">S A Donina</name></author><author><name sortKey="Mironov, A N" sort="Mironov, A N" uniqKey="Mironov A" first="A N" last="Mironov">A N Mironov</name></author><author><name sortKey="Rudenko, L G" sort="Rudenko, L G" uniqKey="Rudenko L" first="L G" last="Rudenko">L G Rudenko</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2011">2011</date><idno type="RBID">pubmed:21813657</idno><idno type="pmid">21813657</idno><idno type="doi">10.1128/CVI.05116-11</idno><idno type="wicri:Area/PubMed/Corpus">000166</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000166</idno><idno type="wicri:Area/PubMed/Curation">000166</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000166</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Memory T-cell immune response in healthy young adults vaccinated with live attenuated influenza A (H5N2) vaccine.</title><author><name sortKey="Chirkova, T V" sort="Chirkova, T V" uniqKey="Chirkova T" first="T V" last="Chirkova">T V Chirkova</name><affiliation wicri:level="1"><nlm:affiliation>Department of Virology, Institute of Experimental Medicine, Acad. Pavlov St. 12, Saint Petersburg 197376, Russia.</nlm:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>Department of Virology, Institute of Experimental Medicine, Acad. Pavlov St. 12, Saint Petersburg 197376</wicri:regionArea></affiliation></author><author><name sortKey="Naykhin, A N" sort="Naykhin, A N" uniqKey="Naykhin A" first="A N" last="Naykhin">A N Naykhin</name></author><author><name sortKey="Petukhova, G D" sort="Petukhova, G D" uniqKey="Petukhova G" first="G D" last="Petukhova">G D Petukhova</name></author><author><name sortKey="Korenkov, D A" sort="Korenkov, D A" uniqKey="Korenkov D" first="D A" last="Korenkov">D A Korenkov</name></author><author><name sortKey="Donina, S A" sort="Donina, S A" uniqKey="Donina S" first="S A" last="Donina">S A Donina</name></author><author><name sortKey="Mironov, A N" sort="Mironov, A N" uniqKey="Mironov A" first="A N" last="Mironov">A N Mironov</name></author><author><name sortKey="Rudenko, L G" sort="Rudenko, L G" uniqKey="Rudenko L" first="L G" last="Rudenko">L G Rudenko</name></author></analytic><series><title level="j">Clinical and vaccine immunology : CVI</title><idno type="eISSN">1556-679X</idno><imprint><date when="2011" type="published">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>CD4-Positive T-Lymphocytes (immunology)</term><term>CD8-Positive T-Lymphocytes (immunology)</term><term>Cytokines (biosynthesis)</term><term>Humans</term><term>Immunization, Secondary (methods)</term><term>Immunologic Memory</term><term>Influenza A Virus, H2N2 Subtype (genetics)</term><term>Influenza A Virus, H2N2 Subtype (immunology)</term><term>Influenza A Virus, H5N2 Subtype (genetics)</term><term>Influenza A Virus, H5N2 Subtype (immunology)</term><term>Influenza Vaccines (administration & dosage)</term><term>Influenza Vaccines (immunology)</term><term>Reassortant Viruses (immunology)</term><term>Vaccination (methods)</term><term>Vaccines, Attenuated (administration & dosage)</term><term>Vaccines, Attenuated (immunology)</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Cytokines (biosynthèse)</term><term>Humains</term><term>Jeune adulte</term><term>Lymphocytes T CD4+ (immunologie)</term><term>Lymphocytes T CD8+ (immunologie)</term><term>Mémoire immunologique</term><term>Rappel de vaccin ()</term><term>Sous-type H2N2 du virus de la grippe A (génétique)</term><term>Sous-type H2N2 du virus de la grippe A (immunologie)</term><term>Sous-type H5N2 du virus de la grippe A (génétique)</term><term>Sous-type H5N2 du virus de la grippe A (immunologie)</term><term>Vaccination ()</term><term>Vaccins antigrippaux (administration et posologie)</term><term>Vaccins antigrippaux (immunologie)</term><term>Vaccins atténués (administration et posologie)</term><term>Vaccins atténués (immunologie)</term><term>Virus recombinants (immunologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Influenza Vaccines</term><term>Vaccines, Attenuated</term></keywords><keywords scheme="MESH" type="chemical" qualifier="biosynthesis" xml:lang="en"><term>Cytokines</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Vaccins antigrippaux</term><term>Vaccins atténués</term></keywords><keywords scheme="MESH" qualifier="biosynthèse" xml:lang="fr"><term>Cytokines</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Influenza A Virus, H2N2 Subtype</term><term>Influenza A Virus, H5N2 Subtype</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Sous-type H2N2 du virus de la grippe A</term><term>Sous-type H5N2 du virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Lymphocytes T CD4+</term><term>Lymphocytes T CD8+</term><term>Sous-type H2N2 du virus de la grippe A</term><term>Sous-type H5N2 du virus de la grippe A</term><term>Vaccins antigrippaux</term><term>Vaccins atténués</term><term>Virus recombinants</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>CD4-Positive T-Lymphocytes</term><term>CD8-Positive T-Lymphocytes</term><term>Influenza A Virus, H2N2 Subtype</term><term>Influenza A Virus, H5N2 Subtype</term><term>Influenza Vaccines</term><term>Reassortant Viruses</term><term>Vaccines, Attenuated</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Immunization, Secondary</term><term>Vaccination</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Immunologic Memory</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Humains</term><term>Jeune adulte</term><term>Mémoire immunologique</term><term>Rappel de vaccin</term><term>Vaccination</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Cellular immune responses of both CD4 and CD8 memory/effector T cells were evaluated in healthy young adults who received two doses of live attenuated influenza A (H5N2) vaccine. The vaccine was developed by reassortment of nonpathogenic avian A/Duck/Potsdam/1402-6/68 (H5N2) and cold-adapted A/Leningrad/134/17/57 (H2N2) viruses. T-cell responses were measured by standard methods of intracellular cytokine staining of gamma interferon (IFN-γ)-producing cells and a novel T-cell recognition of antigen-presenting cells by protein capture (TRAP) assay based on the trogocytosis phenomenon, namely, plasma membrane exchange between interacting immune cells. TRAP enables the detection of activated trogocytosis-positive T cells after virus stimulation. We showed that two doses of live attenuated influenza A (H5N2) vaccine promoted both CD4 and CD8 T-memory-cell responses in peripheral blood of healthy young subjects in the clinical study. Significant differences in geometric mean titers (GMTs) of influenza A (H5N2)-specific IFN-γ(+) cells were observed at day 42 following the second vaccination, while peak levels of trogocytosis(+) T cells were detected earlier, on the 21st day after the second vaccination. The inverse correlation of baseline levels compared to postvaccine fold changes in GMTs of influenza-specific CD4 and CD8 T cells demonstrated that baseline levels of these specific cells could be considered a predictive factor of vaccine immunogenicity.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">21813657</PMID><DateCompleted><Year>2012</Year><Month>01</Month><Day>23</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1556-679X</ISSN><JournalIssue CitedMedium="Internet"><Volume>18</Volume><Issue>10</Issue><PubDate><Year>2011</Year><Month>Oct</Month></PubDate></JournalIssue><Title>Clinical and vaccine immunology : CVI</Title><ISOAbbreviation>Clin. Vaccine Immunol.</ISOAbbreviation></Journal><ArticleTitle>Memory T-cell immune response in healthy young adults vaccinated with live attenuated influenza A (H5N2) vaccine.</ArticleTitle><Pagination><MedlinePgn>1710-8</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1128/CVI.05116-11</ELocationID><Abstract><AbstractText>Cellular immune responses of both CD4 and CD8 memory/effector T cells were evaluated in healthy young adults who received two doses of live attenuated influenza A (H5N2) vaccine. The vaccine was developed by reassortment of nonpathogenic avian A/Duck/Potsdam/1402-6/68 (H5N2) and cold-adapted A/Leningrad/134/17/57 (H2N2) viruses. T-cell responses were measured by standard methods of intracellular cytokine staining of gamma interferon (IFN-γ)-producing cells and a novel T-cell recognition of antigen-presenting cells by protein capture (TRAP) assay based on the trogocytosis phenomenon, namely, plasma membrane exchange between interacting immune cells. TRAP enables the detection of activated trogocytosis-positive T cells after virus stimulation. We showed that two doses of live attenuated influenza A (H5N2) vaccine promoted both CD4 and CD8 T-memory-cell responses in peripheral blood of healthy young subjects in the clinical study. Significant differences in geometric mean titers (GMTs) of influenza A (H5N2)-specific IFN-γ(+) cells were observed at day 42 following the second vaccination, while peak levels of trogocytosis(+) T cells were detected earlier, on the 21st day after the second vaccination. The inverse correlation of baseline levels compared to postvaccine fold changes in GMTs of influenza-specific CD4 and CD8 T cells demonstrated that baseline levels of these specific cells could be considered a predictive factor of vaccine immunogenicity.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Chirkova</LastName><ForeName>T V</ForeName><Initials>TV</Initials><AffiliationInfo><Affiliation>Department of Virology, Institute of Experimental Medicine, Acad. Pavlov St. 12, Saint Petersburg 197376, Russia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Naykhin</LastName><ForeName>A N</ForeName><Initials>AN</Initials></Author><Author ValidYN="Y"><LastName>Petukhova</LastName><ForeName>G D</ForeName><Initials>GD</Initials></Author><Author ValidYN="Y"><LastName>Korenkov</LastName><ForeName>D A</ForeName><Initials>DA</Initials></Author><Author ValidYN="Y"><LastName>Donina</LastName><ForeName>S A</ForeName><Initials>SA</Initials></Author><Author ValidYN="Y"><LastName>Mironov</LastName><ForeName>A N</ForeName><Initials>AN</Initials></Author><Author ValidYN="Y"><LastName>Rudenko</LastName><ForeName>L G</ForeName><Initials>LG</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2011</Year><Month>08</Month><Day>03</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Clin Vaccine Immunol</MedlineTA><NlmUniqueID>101252125</NlmUniqueID><ISSNLinking>1556-679X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D016207">Cytokines</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007252">Influenza Vaccines</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014613">Vaccines, Attenuated</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D015496" MajorTopicYN="N">CD4-Positive T-Lymphocytes</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018414" MajorTopicYN="N">CD8-Positive T-Lymphocytes</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016207" MajorTopicYN="N">Cytokines</DescriptorName><QualifierName UI="Q000096" MajorTopicYN="N">biosynthesis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007117" MajorTopicYN="N">Immunization, Secondary</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007156" MajorTopicYN="Y">Immunologic Memory</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D053121" MajorTopicYN="N">Influenza A Virus, H2N2 Subtype</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D053125" MajorTopicYN="N">Influenza A Virus, H5N2 Subtype</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007252" MajorTopicYN="N">Influenza Vaccines</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016865" MajorTopicYN="N">Reassortant Viruses</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014611" MajorTopicYN="N">Vaccination</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014613" MajorTopicYN="N">Vaccines, Attenuated</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2011</Year><Month>8</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2011</Year><Month>8</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2012</Year><Month>1</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">21813657</ArticleId><ArticleId IdType="pii">CVI.05116-11</ArticleId><ArticleId IdType="doi">10.1128/CVI.05116-11</ArticleId><ArticleId IdType="pmc">PMC3187019</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>J Virol. 2006 Dec;80(23):11756-66</Citation><ArticleIdList><ArticleId IdType="pubmed">16971435</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Med. 2006 Oct;12(10):1208-12</Citation><ArticleIdList><ArticleId IdType="pubmed">17013384</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2007 Mar 15;178(6):3637-47</Citation><ArticleIdList><ArticleId IdType="pubmed">17339461</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Protoc. 2006;1(6):2536-42</Citation><ArticleIdList><ArticleId IdType="pubmed">17406507</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2007 May 1;178(9):5465-72</Citation><ArticleIdList><ArticleId IdType="pubmed">17442927</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2007;2(11):e1204</Citation><ArticleIdList><ArticleId IdType="pubmed">18030338</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2008 Feb 1;180(3):1758-68</Citation><ArticleIdList><ArticleId IdType="pubmed">18209073</ArticleId></ArticleIdList></Reference><Reference><Citation>Respirology. 2008 Mar;13 Suppl 1:S2-9</Citation><ArticleIdList><ArticleId IdType="pubmed">18366524</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2008 Apr 26;371(9622):1427-34</Citation><ArticleIdList><ArticleId IdType="pubmed">18400288</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2008 Apr 26;371(9622):1464-75</Citation><ArticleIdList><ArticleId IdType="pubmed">18440429</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2008;3(7):e2574</Citation><ArticleIdList><ArticleId IdType="pubmed">18596908</ArticleId></ArticleIdList></Reference><Reference><Citation>Vaccine. 2008 Sep 15;26(39):4975-7</Citation><ArticleIdList><ArticleId IdType="pubmed">18514979</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Invest. 2008 Oct;118(10):3478-90</Citation><ArticleIdList><ArticleId IdType="pubmed">18802496</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2008 Dec 1;181(11):8120-32</Citation><ArticleIdList><ArticleId IdType="pubmed">19018005</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Pathog. 2009 May;5(5):e1000409</Citation><ArticleIdList><ArticleId IdType="pubmed">19412338</ArticleId></ArticleIdList></Reference><Reference><Citation>Influenza Other Respir Viruses. 2008 Nov;2(6):203-9</Citation><ArticleIdList><ArticleId IdType="pubmed">19453396</ArticleId></ArticleIdList></Reference><Reference><Citation>Vaccine. 2009 Jun 24;27(31):4079-89</Citation><ArticleIdList><ArticleId IdType="pubmed">19406184</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2009;4(6):e5984</Citation><ArticleIdList><ArticleId IdType="pubmed">19543385</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 2003 Jan 5;305(1):192-200</Citation><ArticleIdList><ArticleId IdType="pubmed">12504552</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Immunol. 2003 Sep;4(9):815</Citation><ArticleIdList><ArticleId IdType="pubmed">12942076</ArticleId></ArticleIdList></Reference><Reference><Citation>Annu Rev Immunol. 2004;22:711-43</Citation><ArticleIdList><ArticleId IdType="pubmed">15032594</ArticleId></ArticleIdList></Reference><Reference><Citation>Virus Res. 2004 Jul;103(1-2):125-32</Citation><ArticleIdList><ArticleId IdType="pubmed">15163500</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Clin Lab Res. 1991;21(2):152-8</Citation><ArticleIdList><ArticleId IdType="pubmed">1687725</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol Methods. 1995 Dec 15;188(1):117-28</Citation><ArticleIdList><ArticleId IdType="pubmed">8551029</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Microbiol. 1999 Apr;37(4):937-43</Citation><ArticleIdList><ArticleId IdType="pubmed">10074505</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2005 Jan 27;352(4):333-40</Citation><ArticleIdList><ArticleId IdType="pubmed">15668219</ArticleId></ArticleIdList></Reference><Reference><Citation>Jpn J Infect Dis. 2005 Aug;58(4):195-207</Citation><ArticleIdList><ArticleId IdType="pubmed">16116250</ArticleId></ArticleIdList></Reference><Reference><Citation>Vaccine. 2006 Jan 30;24(5):541-3</Citation><ArticleIdList><ArticleId IdType="pubmed">16493789</ArticleId></ArticleIdList></Reference><Reference><Citation>Emerg Infect Dis. 2006 Jan;12(1):48-54</Citation><ArticleIdList><ArticleId IdType="pubmed">16494717</ArticleId></ArticleIdList></Reference><Reference><Citation>Eur J Immunol. 2006 Mar;36(3):779-88</Citation><ArticleIdList><ArticleId IdType="pubmed">16482513</ArticleId></ArticleIdList></Reference><Reference><Citation>Immunol Rev. 2006 Jun;211:8-22</Citation><ArticleIdList><ArticleId IdType="pubmed">16824113</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2006 Sep 1;177(5):2888-98</Citation><ArticleIdList><ArticleId IdType="pubmed">16920924</ArticleId></ArticleIdList></Reference><Reference><Citation>Vaccine. 2006 Nov 17;24(47-48):6859-66</Citation><ArticleIdList><ArticleId IdType="pubmed">17050041</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000166 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 000166 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= PubMed
|étape= Curation
|type= RBID
|clé= pubmed:21813657
|texte= Memory T-cell immune response in healthy young adults vaccinated with live attenuated influenza A (H5N2) vaccine.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:21813657" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \
| NlmPubMed2Wicri -a H2N2V1
| This area was generated with Dilib version V0.6.33. |  |