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Influenza: the next pandemic?: A review.

Identifieur interne : 000302 ( PubMed/Corpus ); précédent : 000301; suivant : 000303

Influenza: the next pandemic?: A review.

Auteurs : F O Adungo ; N I Adungo ; S. Bedno ; S L Yingst

Source :

RBID : pubmed:16619723

English descriptors

Abstract

To examine existing information on the recent influenza outbreaks in order to create awareness of a possible influenza pandemic and to suggest future research areas in developing control strategies in Kenya.

DOI: 10.4314/eamj.v82i9.9340
PubMed: 16619723

Links to Exploration step

pubmed:16619723

Le document en format XML

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<title xml:lang="en">Influenza: the next pandemic?: A review.</title>
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<nlm:affiliation>Centre for Infectious and Parasitic Diseases Control Research-Busia, P.O. Box 3 Busia, Kenya.</nlm:affiliation>
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<name sortKey="Adungo, N I" sort="Adungo, N I" uniqKey="Adungo N" first="N I" last="Adungo">N I Adungo</name>
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<name sortKey="Bedno, S" sort="Bedno, S" uniqKey="Bedno S" first="S" last="Bedno">S. Bedno</name>
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<name sortKey="Yingst, S L" sort="Yingst, S L" uniqKey="Yingst S" first="S L" last="Yingst">S L Yingst</name>
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<nlm:affiliation>Centre for Infectious and Parasitic Diseases Control Research-Busia, P.O. Box 3 Busia, Kenya.</nlm:affiliation>
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<name sortKey="Adungo, N I" sort="Adungo, N I" uniqKey="Adungo N" first="N I" last="Adungo">N I Adungo</name>
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<name sortKey="Bedno, S" sort="Bedno, S" uniqKey="Bedno S" first="S" last="Bedno">S. Bedno</name>
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<name sortKey="Yingst, S L" sort="Yingst, S L" uniqKey="Yingst S" first="S L" last="Yingst">S L Yingst</name>
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<term>Cell Culture Techniques</term>
<term>Disease Outbreaks (prevention & control)</term>
<term>Disease Reservoirs (virology)</term>
<term>Global Health</term>
<term>Humans</term>
<term>Influenza A Virus, H2N2 Subtype</term>
<term>Influenza A Virus, H3N2 Subtype</term>
<term>Influenza A Virus, H5N1 Subtype</term>
<term>Influenza in Birds (epidemiology)</term>
<term>Influenza, Human (diagnosis)</term>
<term>Influenza, Human (epidemiology)</term>
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<term>Population Surveillance</term>
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<term>Antiviral Agents</term>
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<term>Kenya</term>
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<term>Influenza, Human</term>
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<term>Influenza in Birds</term>
<term>Influenza, Human</term>
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<term>Disease Outbreaks</term>
<term>Influenza, Human</term>
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<keywords scheme="MESH" qualifier="transmission" xml:lang="en">
<term>Influenza, Human</term>
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<term>Disease Reservoirs</term>
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<term>Animals</term>
<term>Birds</term>
<term>Cell Culture Techniques</term>
<term>Global Health</term>
<term>Humans</term>
<term>Influenza A Virus, H2N2 Subtype</term>
<term>Influenza A Virus, H3N2 Subtype</term>
<term>Influenza A Virus, H5N1 Subtype</term>
<term>Population Surveillance</term>
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<front>
<div type="abstract" xml:lang="en">To examine existing information on the recent influenza outbreaks in order to create awareness of a possible influenza pandemic and to suggest future research areas in developing control strategies in Kenya.</div>
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<Day>01</Day>
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<Year>2019</Year>
<Month>09</Month>
<Day>22</Day>
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<Month>Sep</Month>
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<Title>East African medical journal</Title>
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<AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">To examine existing information on the recent influenza outbreaks in order to create awareness of a possible influenza pandemic and to suggest future research areas in developing control strategies in Kenya.</AbstractText>
<AbstractText Label="DATA SOURCES" NlmCategory="METHODS">Review of literature via Internet, articles, journals and un-refereed features from the media and personal communications.</AbstractText>
<AbstractText Label="DATA SELECTION" NlmCategory="METHODS">Most published data from 1979 to March 2005 found to reveal cases of influenza outbreaks were included in the review. Also, selected articles on the recent outbreaks and professional guidance on influenza infections were critically examined and analyzed.</AbstractText>
<AbstractText Label="DATA EXTRACTION" NlmCategory="METHODS">Abstracts and articles identified were accessed, read to establish relevance to this review.</AbstractText>
<AbstractText Label="DATA SYNTHESIS" NlmCategory="RESULTS">Important points were prioritised and then included as subtitles; below each subtitle, published works were included. Finally, a table of influenza outbreaks and the strains of the viruses involved were drawn as summary.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Influenza is a highly contagious, acute respiratory disease that may spread rapidly and pervasively through a population. Due to the diversity of susceptible reservoirs of influenza viruses and the interspecies transmission recently reported, a mutated strain of the virus to which people have no immunity could cause an influenza pandemic once the virus gains efficient and sustained human-to-human transmission. The fear that avian influenza could be a precursor to the next pandemic is real and inevitable, given the extremely high case-fatality ratio among confirmed cases and that genetic sequencing of influenza A (H5N1) viruses from human cases in Thailand and Vietnam show resistance to the antiviral medication amantadine and rimantadine. This calls for a high level of preparedness to avoid a public health emergency. Nowhere is this paradigm more real than in Africa.</AbstractText>
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