Serological evidence for avian H9N2 influenza virus infections among Romanian agriculture workers.
Identifieur interne : 000116 ( PubMed/Corpus ); précédent : 000115; suivant : 000117Serological evidence for avian H9N2 influenza virus infections among Romanian agriculture workers.
Auteurs : Alexandru Coman ; Daniel N. Maftei ; Whitney S. Krueger ; Gary L. Heil ; John A. Friary ; Razvan M. Chereches ; Emanuela Sirlincan ; Paul Bria ; Claudiu Dragnea ; Iosif Kasler ; Gregory C. GraySource :
- Journal of infection and public health [ 1876-035X ] ; 2013.
English descriptors
- KwdEn :
- Adult, Agriculture, Animals, Antibodies, Viral (blood), Female, Humans, Influenza A Virus, H9N2 Subtype (immunology), Influenza, Human (epidemiology), Influenza, Human (virology), Male, Middle Aged, Neutralization Tests, Occupational Exposure, Romania (epidemiology), Seroepidemiologic Studies, Zoonoses (epidemiology), Zoonoses (virology).
- MESH :
- chemical , blood : Antibodies, Viral.
- geographic , epidemiology : Romania.
- epidemiology : Influenza, Human, Zoonoses.
- immunology : Influenza A Virus, H9N2 Subtype.
- virology : Influenza, Human, Zoonoses.
- Adult, Agriculture, Animals, Female, Humans, Male, Middle Aged, Neutralization Tests, Occupational Exposure, Seroepidemiologic Studies.
Abstract
In recent years, wild birds have introduced multiple highly pathogenic avian influenza (HPAI) H5N1 virus infections in Romanian poultry. In 2005 HPAI infections were widespread among domestic poultry and anecdotal reports suggested domestic pigs may also have been exposed. We sought to examine evidence for zoonotic influenza infections among Romanian agriculture workers. Between 2009 and 2010, 363 adult participants were enrolled in a cross-sectional, seroepidemiological study. Confined animal feeding operation (CAFO) swine workers in Tulcea and small, traditional backyard farmers in Cluj-Napoca were enrolled, as well as a non-animal exposed control group from Cluj-Napoca. Enrollment sera were examined for serological evidence of previous infection with 9 avian and 3 human influenza virus strains. Serologic assays showed no evidence of previous infection with 7 low pathogenic avian influenza viruses or with HPAI H5N1. However, 33 participants (9.1%) had elevated microneutralization antibody titers against avian-like A/Hong Kong/1073/1999(H9N2), 5 with titers ≥ 1:80 whom all reported exposure to poultry. Moderate poultry exposure was significantly associated with elevated titers after controlling for the subjects' age (adjusted OR = 3.6; 95% CI, 1.1-12.1). There was no evidence that previous infection with human H3N2 or H2N2 viruses were confounding the H9N2 seroreactivity. These data suggest that H9N2 virus may have circulated in Romanian poultry and occasionally infected man.
DOI: 10.1016/j.jiph.2013.05.003
PubMed: 23999337
Links to Exploration step
pubmed:23999337Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Serological evidence for avian H9N2 influenza virus infections among Romanian agriculture workers.</title><author><name sortKey="Coman, Alexandru" sort="Coman, Alexandru" uniqKey="Coman A" first="Alexandru" last="Coman">Alexandru Coman</name><affiliation><nlm:affiliation>Center for Health Policy and Public Health, Institute for Social Research, Faculty of Political, Administrative and Communication Sciences, Babes-Bolyai University, Cluj-Napoca, Romania.</nlm:affiliation></affiliation></author><author><name sortKey="Maftei, Daniel N" sort="Maftei, Daniel N" uniqKey="Maftei D" first="Daniel N" last="Maftei">Daniel N. Maftei</name></author><author><name sortKey="Krueger, Whitney S" sort="Krueger, Whitney S" uniqKey="Krueger W" first="Whitney S" last="Krueger">Whitney S. Krueger</name></author><author><name sortKey="Heil, Gary L" sort="Heil, Gary L" uniqKey="Heil G" first="Gary L" last="Heil">Gary L. Heil</name></author><author><name sortKey="Friary, John A" sort="Friary, John A" uniqKey="Friary J" first="John A" last="Friary">John A. Friary</name></author><author><name sortKey="Chereches, Razvan M" sort="Chereches, Razvan M" uniqKey="Chereches R" first="Razvan M" last="Chereches">Razvan M. Chereches</name></author><author><name sortKey="Sirlincan, Emanuela" sort="Sirlincan, Emanuela" uniqKey="Sirlincan E" first="Emanuela" last="Sirlincan">Emanuela Sirlincan</name></author><author><name sortKey="Bria, Paul" sort="Bria, Paul" uniqKey="Bria P" first="Paul" last="Bria">Paul Bria</name></author><author><name sortKey="Dragnea, Claudiu" sort="Dragnea, Claudiu" uniqKey="Dragnea C" first="Claudiu" last="Dragnea">Claudiu Dragnea</name></author><author><name sortKey="Kasler, Iosif" sort="Kasler, Iosif" uniqKey="Kasler I" first="Iosif" last="Kasler">Iosif Kasler</name></author><author><name sortKey="Gray, Gregory C" sort="Gray, Gregory C" uniqKey="Gray G" first="Gregory C" last="Gray">Gregory C. Gray</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2013">2013</date><idno type="RBID">pubmed:23999337</idno><idno type="pmid">23999337</idno><idno type="doi">10.1016/j.jiph.2013.05.003</idno><idno type="wicri:Area/PubMed/Corpus">000116</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000116</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Serological evidence for avian H9N2 influenza virus infections among Romanian agriculture workers.</title><author><name sortKey="Coman, Alexandru" sort="Coman, Alexandru" uniqKey="Coman A" first="Alexandru" last="Coman">Alexandru Coman</name><affiliation><nlm:affiliation>Center for Health Policy and Public Health, Institute for Social Research, Faculty of Political, Administrative and Communication Sciences, Babes-Bolyai University, Cluj-Napoca, Romania.</nlm:affiliation></affiliation></author><author><name sortKey="Maftei, Daniel N" sort="Maftei, Daniel N" uniqKey="Maftei D" first="Daniel N" last="Maftei">Daniel N. Maftei</name></author><author><name sortKey="Krueger, Whitney S" sort="Krueger, Whitney S" uniqKey="Krueger W" first="Whitney S" last="Krueger">Whitney S. Krueger</name></author><author><name sortKey="Heil, Gary L" sort="Heil, Gary L" uniqKey="Heil G" first="Gary L" last="Heil">Gary L. Heil</name></author><author><name sortKey="Friary, John A" sort="Friary, John A" uniqKey="Friary J" first="John A" last="Friary">John A. Friary</name></author><author><name sortKey="Chereches, Razvan M" sort="Chereches, Razvan M" uniqKey="Chereches R" first="Razvan M" last="Chereches">Razvan M. Chereches</name></author><author><name sortKey="Sirlincan, Emanuela" sort="Sirlincan, Emanuela" uniqKey="Sirlincan E" first="Emanuela" last="Sirlincan">Emanuela Sirlincan</name></author><author><name sortKey="Bria, Paul" sort="Bria, Paul" uniqKey="Bria P" first="Paul" last="Bria">Paul Bria</name></author><author><name sortKey="Dragnea, Claudiu" sort="Dragnea, Claudiu" uniqKey="Dragnea C" first="Claudiu" last="Dragnea">Claudiu Dragnea</name></author><author><name sortKey="Kasler, Iosif" sort="Kasler, Iosif" uniqKey="Kasler I" first="Iosif" last="Kasler">Iosif Kasler</name></author><author><name sortKey="Gray, Gregory C" sort="Gray, Gregory C" uniqKey="Gray G" first="Gregory C" last="Gray">Gregory C. Gray</name></author></analytic><series><title level="j">Journal of infection and public health</title><idno type="eISSN">1876-035X</idno><imprint><date when="2013" type="published">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Agriculture</term><term>Animals</term><term>Antibodies, Viral (blood)</term><term>Female</term><term>Humans</term><term>Influenza A Virus, H9N2 Subtype (immunology)</term><term>Influenza, Human (epidemiology)</term><term>Influenza, Human (virology)</term><term>Male</term><term>Middle Aged</term><term>Neutralization Tests</term><term>Occupational Exposure</term><term>Romania (epidemiology)</term><term>Seroepidemiologic Studies</term><term>Zoonoses (epidemiology)</term><term>Zoonoses (virology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Viral</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Romania</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term><term>Zoonoses</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Influenza A Virus, H9N2 Subtype</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Influenza, Human</term><term>Zoonoses</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Agriculture</term><term>Animals</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neutralization Tests</term><term>Occupational Exposure</term><term>Seroepidemiologic Studies</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In recent years, wild birds have introduced multiple highly pathogenic avian influenza (HPAI) H5N1 virus infections in Romanian poultry. In 2005 HPAI infections were widespread among domestic poultry and anecdotal reports suggested domestic pigs may also have been exposed. We sought to examine evidence for zoonotic influenza infections among Romanian agriculture workers. Between 2009 and 2010, 363 adult participants were enrolled in a cross-sectional, seroepidemiological study. Confined animal feeding operation (CAFO) swine workers in Tulcea and small, traditional backyard farmers in Cluj-Napoca were enrolled, as well as a non-animal exposed control group from Cluj-Napoca. Enrollment sera were examined for serological evidence of previous infection with 9 avian and 3 human influenza virus strains. Serologic assays showed no evidence of previous infection with 7 low pathogenic avian influenza viruses or with HPAI H5N1. However, 33 participants (9.1%) had elevated microneutralization antibody titers against avian-like A/Hong Kong/1073/1999(H9N2), 5 with titers ≥ 1:80 whom all reported exposure to poultry. Moderate poultry exposure was significantly associated with elevated titers after controlling for the subjects' age (adjusted OR = 3.6; 95% CI, 1.1-12.1). There was no evidence that previous infection with human H3N2 or H2N2 viruses were confounding the H9N2 seroreactivity. These data suggest that H9N2 virus may have circulated in Romanian poultry and occasionally infected man.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">23999337</PMID><DateCompleted><Year>2014</Year><Month>06</Month><Day>23</Day></DateCompleted><DateRevised><Year>2016</Year><Month>05</Month><Day>18</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1876-035X</ISSN><JournalIssue CitedMedium="Internet"><Volume>6</Volume><Issue>6</Issue><PubDate><Year>2013</Year><Month>Dec</Month></PubDate></JournalIssue><Title>Journal of infection and public health</Title><ISOAbbreviation>J Infect Public Health</ISOAbbreviation></Journal><ArticleTitle>Serological evidence for avian H9N2 influenza virus infections among Romanian agriculture workers.</ArticleTitle><Pagination><MedlinePgn>438-47</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jiph.2013.05.003</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S1876-0341(13)00077-4</ELocationID><Abstract><AbstractText>In recent years, wild birds have introduced multiple highly pathogenic avian influenza (HPAI) H5N1 virus infections in Romanian poultry. In 2005 HPAI infections were widespread among domestic poultry and anecdotal reports suggested domestic pigs may also have been exposed. We sought to examine evidence for zoonotic influenza infections among Romanian agriculture workers. Between 2009 and 2010, 363 adult participants were enrolled in a cross-sectional, seroepidemiological study. Confined animal feeding operation (CAFO) swine workers in Tulcea and small, traditional backyard farmers in Cluj-Napoca were enrolled, as well as a non-animal exposed control group from Cluj-Napoca. Enrollment sera were examined for serological evidence of previous infection with 9 avian and 3 human influenza virus strains. Serologic assays showed no evidence of previous infection with 7 low pathogenic avian influenza viruses or with HPAI H5N1. However, 33 participants (9.1%) had elevated microneutralization antibody titers against avian-like A/Hong Kong/1073/1999(H9N2), 5 with titers ≥ 1:80 whom all reported exposure to poultry. Moderate poultry exposure was significantly associated with elevated titers after controlling for the subjects' age (adjusted OR = 3.6; 95% CI, 1.1-12.1). There was no evidence that previous infection with human H3N2 or H2N2 viruses were confounding the H9N2 seroreactivity. These data suggest that H9N2 virus may have circulated in Romanian poultry and occasionally infected man.</AbstractText><CopyrightInformation>Copyright © 2013 King Saud Bin Abdulaziz University for Health Sciences. Published by Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Coman</LastName><ForeName>Alexandru</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Center for Health Policy and Public Health, Institute for Social Research, Faculty of Political, Administrative and Communication Sciences, Babes-Bolyai University, Cluj-Napoca, Romania.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Maftei</LastName><ForeName>Daniel N</ForeName><Initials>DN</Initials></Author><Author ValidYN="Y"><LastName>Krueger</LastName><ForeName>Whitney S</ForeName><Initials>WS</Initials></Author><Author ValidYN="Y"><LastName>Heil</LastName><ForeName>Gary L</ForeName><Initials>GL</Initials></Author><Author ValidYN="Y"><LastName>Friary</LastName><ForeName>John A</ForeName><Initials>JA</Initials></Author><Author ValidYN="Y"><LastName>Chereches</LastName><ForeName>Razvan M</ForeName><Initials>RM</Initials></Author><Author ValidYN="Y"><LastName>Sirlincan</LastName><ForeName>Emanuela</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Bria</LastName><ForeName>Paul</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Dragnea</LastName><ForeName>Claudiu</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Kasler</LastName><ForeName>Iosif</ForeName><Initials>I</Initials></Author><Author ValidYN="Y"><LastName>Gray</LastName><ForeName>Gregory C</ForeName><Initials>GC</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2013</Year><Month>06</Month><Day>20</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Infect Public Health</MedlineTA><NlmUniqueID>101487384</NlmUniqueID><ISSNLinking>1876-0341</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000914">Antibodies, Viral</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="ErratumIn"><RefSource>J Infect Public Health. 2018 Nov - Dec;11(6):902</RefSource><PMID Version="1">30385014</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000383" MajorTopicYN="Y">Agriculture</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000914" MajorTopicYN="N">Antibodies, Viral</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D053127" MajorTopicYN="N">Influenza A Virus, H9N2 Subtype</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009500" MajorTopicYN="N">Neutralization Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016273" MajorTopicYN="Y">Occupational Exposure</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012383" MajorTopicYN="N" Type="Geographic">Romania</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016036" MajorTopicYN="N">Seroepidemiologic Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015047" MajorTopicYN="N">Zoonoses</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Agriculture</Keyword><Keyword MajorTopicYN="N">Communicable diseases</Keyword><Keyword MajorTopicYN="N">Emerging</Keyword><Keyword MajorTopicYN="N">Influenza A virus</Keyword><Keyword MajorTopicYN="N">Seroepidemiologic studies</Keyword><Keyword MajorTopicYN="N">Zoonoses</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year><Month>04</Month><Day>15</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2013</Year><Month>05</Month><Day>22</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2013</Year><Month>05</Month><Day>24</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>9</Month><Day>4</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2013</Year><Month>9</Month><Day>4</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>6</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">23999337</ArticleId><ArticleId IdType="pii">S1876-0341(13)00077-4</ArticleId><ArticleId IdType="doi">10.1016/j.jiph.2013.05.003</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000116 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000116 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:23999337
|texte= Serological evidence for avian H9N2 influenza virus infections among Romanian agriculture workers.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:23999337" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a H2N2V1
| This area was generated with Dilib version V0.6.33. |  |