H2N2V1, PubMed, Checkpoint, bibRecord, 000230

Non-random reassortment in human influenza A viruses.

Identifieur interne : 000230 ( PubMed/Checkpoint ); précédent : 000229; suivant : 000231

Non-random reassortment in human influenza A viruses.

Auteurs : Raul Rabadan [États-Unis] ; Arnold J. Levine ; Michael Krasnitz

Source :

Influenza and other respiratory viruses [ 1750-2659 ] ; 2008.

RBID : pubmed:19453489

Descripteurs français

KwdFr :
- Bases de données d'acides nucléiques, Biologie informatique, Grippe humaine (virologie), Humains, Nouvelle-Zélande, Sous-type H3N2 du virus de la grippe A (génétique), Sous-type H3N2 du virus de la grippe A (isolement et purification), Virus recombinants (génétique), Virus recombinants (isolement et purification), État de New York.
MESH :
- génétique : Sous-type H3N2 du virus de la grippe A, Virus recombinants.
- isolement et purification : Sous-type H3N2 du virus de la grippe A, Virus recombinants.
- virologie : Grippe humaine.
- Bases de données d'acides nucléiques, Biologie informatique, Humains, Nouvelle-Zélande, État de New York.
Wicri :
- geographic : Nouvelle-Zélande.

English descriptors

KwdEn :
- Computational Biology, Databases, Nucleic Acid, Humans, Influenza A Virus, H3N2 Subtype (genetics), Influenza A Virus, H3N2 Subtype (isolation & purification), Influenza, Human (virology), New York, New Zealand, Reassortant Viruses (genetics), Reassortant Viruses (isolation & purification).
MESH :
- geographic : New York, New Zealand.
- genetics : Influenza A Virus, H3N2 Subtype, Reassortant Viruses.
- isolation & purification : Influenza A Virus, H3N2 Subtype, Reassortant Viruses.
- virology : Influenza, Human.
- Computational Biology, Databases, Nucleic Acid, Humans.

Abstract

The influenza A virus has two basic modes of evolution. Because of a high error rate in the process of replication by RNA polymerase, the viral genome drifts via accumulated mutations. The second mode of evolution is termed a shift, which results from the reassortment of the eight segments of this virus. When two different influenza viruses co-infect the same host cell, new virions can be released that contain segments from both parental strains. This type of shift has been the source of at least two of the influenza pandemics in the 20th century (H2N2 in 1957 and H3N2 in 1968).

DOI: 10.1111/j.1750-2659.2007.00030.x
PubMed: 19453489

Affiliations:

États-Unis

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: 000268
to stream PubMed, to step Curation: 000268

Links to Exploration step

pubmed:19453489

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Non-random reassortment in human influenza A viruses.</title>
<author><name sortKey="Rabadan, Raul" sort="Rabadan, Raul" uniqKey="Rabadan R" first="Raul" last="Rabadan">Raul Rabadan</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute for Advanced Study, Einstein Dr, Princeton, NJ 08540, USA. rabadan@ias.edu</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Institute for Advanced Study, Einstein Dr, Princeton, NJ 08540</wicri:regionArea>
<wicri:noRegion>NJ 08540</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Levine, Arnold J" sort="Levine, Arnold J" uniqKey="Levine A" first="Arnold J" last="Levine">Arnold J. Levine</name>
</author>
<author><name sortKey="Krasnitz, Michael" sort="Krasnitz, Michael" uniqKey="Krasnitz M" first="Michael" last="Krasnitz">Michael Krasnitz</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2008">2008</date>
<idno type="RBID">pubmed:19453489</idno>
<idno type="pmid">19453489</idno>
<idno type="doi">10.1111/j.1750-2659.2007.00030.x</idno>
<idno type="wicri:Area/PubMed/Corpus">000268</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000268</idno>
<idno type="wicri:Area/PubMed/Curation">000268</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000268</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000230</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000230</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Non-random reassortment in human influenza A viruses.</title>
<author><name sortKey="Rabadan, Raul" sort="Rabadan, Raul" uniqKey="Rabadan R" first="Raul" last="Rabadan">Raul Rabadan</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute for Advanced Study, Einstein Dr, Princeton, NJ 08540, USA. rabadan@ias.edu</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Institute for Advanced Study, Einstein Dr, Princeton, NJ 08540</wicri:regionArea>
<wicri:noRegion>NJ 08540</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Levine, Arnold J" sort="Levine, Arnold J" uniqKey="Levine A" first="Arnold J" last="Levine">Arnold J. Levine</name>
</author>
<author><name sortKey="Krasnitz, Michael" sort="Krasnitz, Michael" uniqKey="Krasnitz M" first="Michael" last="Krasnitz">Michael Krasnitz</name>
</author>
</analytic>
<series><title level="j">Influenza and other respiratory viruses</title>
<idno type="eISSN">1750-2659</idno>
<imprint><date when="2008" type="published">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Computational Biology</term>
<term>Databases, Nucleic Acid</term>
<term>Humans</term>
<term>Influenza A Virus, H3N2 Subtype (genetics)</term>
<term>Influenza A Virus, H3N2 Subtype (isolation & purification)</term>
<term>Influenza, Human (virology)</term>
<term>New York</term>
<term>New Zealand</term>
<term>Reassortant Viruses (genetics)</term>
<term>Reassortant Viruses (isolation & purification)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Bases de données d'acides nucléiques</term>
<term>Biologie informatique</term>
<term>Grippe humaine (virologie)</term>
<term>Humains</term>
<term>Nouvelle-Zélande</term>
<term>Sous-type H3N2 du virus de la grippe A (génétique)</term>
<term>Sous-type H3N2 du virus de la grippe A (isolement et purification)</term>
<term>Virus recombinants (génétique)</term>
<term>Virus recombinants (isolement et purification)</term>
<term>État de New York</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>New York</term>
<term>New Zealand</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Influenza A Virus, H3N2 Subtype</term>
<term>Reassortant Viruses</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Sous-type H3N2 du virus de la grippe A</term>
<term>Virus recombinants</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Influenza A Virus, H3N2 Subtype</term>
<term>Reassortant Viruses</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Sous-type H3N2 du virus de la grippe A</term>
<term>Virus recombinants</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Computational Biology</term>
<term>Databases, Nucleic Acid</term>
<term>Humans</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Bases de données d'acides nucléiques</term>
<term>Biologie informatique</term>
<term>Humains</term>
<term>Nouvelle-Zélande</term>
<term>État de New York</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Nouvelle-Zélande</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The influenza A virus has two basic modes of evolution. Because of a high error rate in the process of replication by RNA polymerase, the viral genome drifts via accumulated mutations. The second mode of evolution is termed a shift, which results from the reassortment of the eight segments of this virus. When two different influenza viruses co-infect the same host cell, new virions can be released that contain segments from both parental strains. This type of shift has been the source of at least two of the influenza pandemics in the 20th century (H2N2 in 1957 and H3N2 in 1968).</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">19453489</PMID>
<DateCompleted><Year>2009</Year>
<Month>06</Month>
<Day>08</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>11</Month>
<Day>13</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1750-2659</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>2</Volume>
<Issue>1</Issue>
<PubDate><Year>2008</Year>
<Month>Jan</Month>
</PubDate>
</JournalIssue>
<Title>Influenza and other respiratory viruses</Title>
<ISOAbbreviation>Influenza Other Respir Viruses</ISOAbbreviation>
</Journal>
<ArticleTitle>Non-random reassortment in human influenza A viruses.</ArticleTitle>
<Pagination><MedlinePgn>9-22</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1111/j.1750-2659.2007.00030.x</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The influenza A virus has two basic modes of evolution. Because of a high error rate in the process of replication by RNA polymerase, the viral genome drifts via accumulated mutations. The second mode of evolution is termed a shift, which results from the reassortment of the eight segments of this virus. When two different influenza viruses co-infect the same host cell, new virions can be released that contain segments from both parental strains. This type of shift has been the source of at least two of the influenza pandemics in the 20th century (H2N2 in 1957 and H3N2 in 1968).</AbstractText>
<AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">The methods to measure these genetic shifts have not yet provided a quantitative answer to questions such as: what is the rate of genetic reassortment during a local epidemic? Are all possible reassortments equally likely or are there preferred patterns?</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">To answer these questions and provide a quantitative way to measure genetic shifts, a new method for detecting reassortments from nucleotide sequence data was created that does not rely upon phylogenetic analysis. Two different sequence databases were used: human H3N2 viruses isolated in New York State between 1995 and 2006, and human H3N2 viruses isolated in New Zealand between 2000 and 2005.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Using this new method, we were able to reproduce all the reassortments found in earlier works, as well as detect, with very high confidence, many reassortments that were not detected by previous authors. We obtain a lower bound on the reassortment rate of 2-3 events per year, and find a clear preference for reassortments involving only one segment, most often hemagglutinin or neuraminidase. At a lower frequency several segments appear to reassort in vivo in defined groups as has been suggested previously in vitro.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Our results strongly suggest that the patterns of reassortment in the viral population are not random. Deciphering these patterns can be a useful tool in attempting to understand and predict possible influenza pandemics.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Rabadan</LastName>
<ForeName>Raul</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Institute for Advanced Study, Einstein Dr, Princeton, NJ 08540, USA. rabadan@ias.edu</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Levine</LastName>
<ForeName>Arnold J</ForeName>
<Initials>AJ</Initials>
</Author>
<Author ValidYN="Y"><LastName>Krasnitz</LastName>
<ForeName>Michael</ForeName>
<Initials>M</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>Influenza Other Respir Viruses</MedlineTA>
<NlmUniqueID>101304007</NlmUniqueID>
<ISSNLinking>1750-2640</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D019295" MajorTopicYN="N">Computational Biology</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D030561" MajorTopicYN="N">Databases, Nucleic Acid</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D053122" MajorTopicYN="N">Influenza A Virus, H3N2 Subtype</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009518" MajorTopicYN="N" Type="Geographic">New York</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009520" MajorTopicYN="N" Type="Geographic">New Zealand</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016865" MajorTopicYN="N">Reassortant Viruses</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2009</Year>
<Month>5</Month>
<Day>21</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2008</Year>
<Month>1</Month>
<Day>1</Day>
<Hour>0</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2009</Year>
<Month>6</Month>
<Day>9</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">19453489</ArticleId>
<ArticleId IdType="pii">IRV030</ArticleId>
<ArticleId IdType="doi">10.1111/j.1750-2659.2007.00030.x</ArticleId>
<ArticleId IdType="pmc">PMC4634327</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Nat Rev Genet. 2007 Mar;8(3):196-205</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17262054</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2006 Dec;2(12):e125</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17140286</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2008 Mar;82(5):2295-304</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18094182</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virus Res. 2003 Dec;98(1):35-44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14609628</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Arch Virol. 1998;143(8):1585-98</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9739336</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2006 Dec;80(23):11887-91</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16987977</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Biol Evol. 2006 Dec;23(12):2336-41</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16945980</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1998 Oct;72(10):8021-31</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9733841</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Biol. 2005 Sep;3(9):e300</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16026181</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 2004 Oct 10;328(1):101-19</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15380362</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 1991 May 15;88(10):4270-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1840695</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 1979 May;95(1):269-74</Citation>
<ArticleIdList><ArticleId IdType="pubmed">442543</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Phylogenet Evol. 1996 Feb;5(1):247-58</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8673293</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vaccine. 2006 Nov 10;24(44-46):6683-90</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17030498</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>États-Unis</li>
</country>
</list>
<tree><noCountry><name sortKey="Krasnitz, Michael" sort="Krasnitz, Michael" uniqKey="Krasnitz M" first="Michael" last="Krasnitz">Michael Krasnitz</name>
<name sortKey="Levine, Arnold J" sort="Levine, Arnold J" uniqKey="Levine A" first="Arnold J" last="Levine">Arnold J. Levine</name>
</noCountry>
<country name="États-Unis"><noRegion><name sortKey="Rabadan, Raul" sort="Rabadan, Raul" uniqKey="Rabadan R" first="Raul" last="Rabadan">Raul Rabadan</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/PubMed/Checkpoint

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000230 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 000230 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    H2N2V1
   |flux=    PubMed
   |étape=   Checkpoint
   |type=    RBID
   |clé=     pubmed:19453489
   |texte=   Non-random reassortment in human influenza A viruses.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i   -Sk "pubmed:19453489" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd   \
       | NlmPubMed2Wicri -a H2N2V1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 14 19:59:40 2020. Site generation: Thu Mar 25 15:38:26 2021

	Serveur d'exploration H2N2
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration H2N2

Non-random reassortment in human influenza A viruses.

Non-random reassortment in human influenza A viruses.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki