H2N2V1, PubMed, Checkpoint, bibRecord, 000223

The pig as a mixing vessel for influenza viruses: Human and veterinary implications.

Identifieur interne : 000223 ( PubMed/Checkpoint ); précédent : 000222; suivant : 000224

The pig as a mixing vessel for influenza viruses: Human and veterinary implications.

Auteurs : Wenjun Ma [États-Unis] ; Robert E. Kahn ; Juergen A. Richt

Source :

Journal of molecular and genetic medicine : an international journal of biomedical research [ 1747-0862 ] ; 2008.

RBID : pubmed:19565018

Abstract

Influenza A viruses are highly infectious respiratory pathogens that can infect many species. Birds are the reservoir for all known influenza A subtypes; and novel influenza viruses can emerge from birds and infect mammalian species including humans. Because swine are susceptible to infection with both avian and human influenza viruses, novel reassortant influenza viruses can be generated in this mammalian species by reassortment of influenza viral segments leading to the "mixing vessel" theory. There is no direct evidence that the reassortment events culminating in the 1918, 1957 or 1968 pandemic influenza viruses originated from pigs. Genetic reassortment among avian, human and/or swine influenza virus gene segments has occurred in pigs and some novel reassortant swine viruses have been transmitted to humans. Notably, novel reassortant H2N3 influenza viruses isolated from the US pigs, most likely infected with avian influenza viruses through surface water collected in ponds for cleaning barns and watering animals, had a similar genetic make-up to early isolates (1957) of the H2N2 human pandemic. These novel H2N3 swine viruses were able to cause disease in swine and mice and were infectious and highly transmissible in swine and ferrets without prior adaptation. The preceding example shows that pigs could transmit novel viruses from an avian reservoir to other mammalian species. Importantly, H2 viruses pose a substantial risk to humans because they have been absent from mammalian species since 1968 and people born after 1968 have little preexisting immunity to the H2 subtype. It is difficult to predict which virus will cause the next human pandemic and when that pandemic might begin. Importantly, the establishment and spread of a reassorted mammalian-adapted virus from pigs to humans could happen anywhere in the world. Therefore, both human and veterinary research needs to give more attention to potential cross-species transmission capacity of influenza A viruses.

PubMed: 19565018

Affiliations:

États-Unis

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<front><div type="abstract" xml:lang="en">Influenza A viruses are highly infectious respiratory pathogens that can infect many species. Birds are the reservoir for all known influenza A subtypes; and novel influenza viruses can emerge from birds and infect mammalian species including humans. Because swine are susceptible to infection with both avian and human influenza viruses, novel reassortant influenza viruses can be generated in this mammalian species by reassortment of influenza viral segments leading to the "mixing vessel" theory. There is no direct evidence that the reassortment events culminating in the 1918, 1957 or 1968 pandemic influenza viruses originated from pigs. Genetic reassortment among avian, human and/or swine influenza virus gene segments has occurred in pigs and some novel reassortant swine viruses have been transmitted to humans. Notably, novel reassortant H2N3 influenza viruses isolated from the US pigs, most likely infected with avian influenza viruses through surface water collected in ponds for cleaning barns and watering animals, had a similar genetic make-up to early isolates (1957) of the H2N2 human pandemic. These novel H2N3 swine viruses were able to cause disease in swine and mice and were infectious and highly transmissible in swine and ferrets without prior adaptation. The preceding example shows that pigs could transmit novel viruses from an avian reservoir to other mammalian species. Importantly, H2 viruses pose a substantial risk to humans because they have been absent from mammalian species since 1968 and people born after 1968 have little preexisting immunity to the H2 subtype. It is difficult to predict which virus will cause the next human pandemic and when that pandemic might begin. Importantly, the establishment and spread of a reassorted mammalian-adapted virus from pigs to humans could happen anywhere in the world. Therefore, both human and veterinary research needs to give more attention to potential cross-species transmission capacity of influenza A viruses.</div>
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<Abstract><AbstractText>Influenza A viruses are highly infectious respiratory pathogens that can infect many species. Birds are the reservoir for all known influenza A subtypes; and novel influenza viruses can emerge from birds and infect mammalian species including humans. Because swine are susceptible to infection with both avian and human influenza viruses, novel reassortant influenza viruses can be generated in this mammalian species by reassortment of influenza viral segments leading to the "mixing vessel" theory. There is no direct evidence that the reassortment events culminating in the 1918, 1957 or 1968 pandemic influenza viruses originated from pigs. Genetic reassortment among avian, human and/or swine influenza virus gene segments has occurred in pigs and some novel reassortant swine viruses have been transmitted to humans. Notably, novel reassortant H2N3 influenza viruses isolated from the US pigs, most likely infected with avian influenza viruses through surface water collected in ponds for cleaning barns and watering animals, had a similar genetic make-up to early isolates (1957) of the H2N2 human pandemic. These novel H2N3 swine viruses were able to cause disease in swine and mice and were infectious and highly transmissible in swine and ferrets without prior adaptation. The preceding example shows that pigs could transmit novel viruses from an avian reservoir to other mammalian species. Importantly, H2 viruses pose a substantial risk to humans because they have been absent from mammalian species since 1968 and people born after 1968 have little preexisting immunity to the H2 subtype. It is difficult to predict which virus will cause the next human pandemic and when that pandemic might begin. Importantly, the establishment and spread of a reassorted mammalian-adapted virus from pigs to humans could happen anywhere in the world. Therefore, both human and veterinary research needs to give more attention to potential cross-species transmission capacity of influenza A viruses.</AbstractText>
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<ArticleIdList><ArticleId IdType="pubmed">19565018</ArticleId>
<ArticleId IdType="pmc">PMC2702078</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Vet Microbiol. 2002 Aug 25;88(2):107-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12135631</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 1983 Sep;129(2):521-3</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6623931</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Evol Appl. 2008 Feb;1(1):172-82</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25567500</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2006 May;12(5):787-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16704839</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Microbes Infect. 2004 Aug;6(10):919-25</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15310468</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vector Borne Zoonotic Dis. 2004 Fall;4(3):177-89</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15631061</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Bull World Health Organ. 1972;47(4):489-91</Citation>
<ArticleIdList><ArticleId IdType="pubmed">4540999</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2005 Aug;79(16):10821-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16051873</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virus Res. 2004 Jul;103(1-2):67-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15163491</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virus Genes. 2004 Aug;29(1):81-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15215686</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 1982 Mar;117(2):485-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7064356</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet Infect Dis. 2008 Oct;8(10):650-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18922487</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1999 Oct;73(10):8851-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10482643</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2007 May 1;104(18):7313-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17460034</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2005 Oct 7;310(5745):77-80</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16210530</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2006 Apr 21;312(5772):394-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16627737</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2007 Jul;13(7):1074-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18214184</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2006 Mar;44(3):1123-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16517910</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virus Genes. 2008 Jun;36(3):461-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18401696</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Rev Microbiol. 2005 Aug;3(8):591-600</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16064053</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vet Microbiol. 2000 May 22;74(1-2):29-46</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10799776</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1996 Nov;70(11):8041-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8892928</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biol Direct. 2008;3:11</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18371199</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1989 Nov;63(11):4603-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2795713</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Med. 2006 Jun;3(6):e135</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17214503</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2007 Sep;13(9):1340-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18252105</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2007 May 11;3(5):e61</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17500589</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect. 2000 May;40(3):218-28</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10908015</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2004 Jan 17;363(9404):234-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14738798</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2005 Jan 27;352(4):333-40</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15668219</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virus Genes. 1995;11(2-3):209-15</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8828147</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Anim Health Res Rev. 2007 Jun;8(1):1-21</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17692139</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 1994 Sep;75 ( Pt 9):2183-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8077918</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Top Microbiol Immunol. 2007;315:67-83</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17848061</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10682-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16030144</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 1983 Jun;127(2):361-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6868370</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 1989 Nov;173(1):317-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2815586</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 1993 Mar;193(1):503-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8438586</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Philos Trans R Soc Lond B Biol Sci. 2001 Jun 29;356(1410):791-3</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11405921</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2006 Mar 18;367(9514):875</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16546517</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2005 Nov 18;310(5751):1112-3</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16293738</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2004 Sep;42(9):4349-54</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15365042</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2008 Apr 26;371(9622):1464-75</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18440429</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Biotechnol. 2008 Jan;26(1):107-13</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18176555</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2004 Mar 18;350(12):1179-88</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14985470</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Biotechnol. 2008 Jan;26(1):60-2</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18183018</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2006 May;80(10):5092-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16641303</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vet Microbiol. 2008 Sep 18;131(1-2):82-92</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18403137</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1998 Sep;72(9):7367-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9696833</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 1998 Dec;79 ( Pt 12):2947-55</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9880008</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2008;3(8):e2923</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18698430</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2000 Oct;74(19):9322-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10982381</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2008 Jul 10;454(7201):162</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18615064</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2006 Mar 23;440(7083):435-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16554799</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virus Res. 2002 Aug;87(2):173-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12191781</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Top Microbiol Immunol. 2007;315:1-31</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17848058</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2007 Jun 15;316(5831):1553</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17569833</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biochem Biophys Res Commun. 2007 Apr 27;356(1):91-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17346674</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2007 Dec;13(12):1865-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18258037</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vet Rec. 2007 Mar 10;160(10):343-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17351179</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 2006 Mar 15;346(2):278-86</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16325879</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2007 Aug 10;317(5839):825-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17690300</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biol Direct. 2006;1:34</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17067369</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Bull World Health Organ. 1981;59(1):75-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6973418</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vet Rec. 2005 Nov 26;157(22):673-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16311375</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2006 Apr 27;440(7088):E8; discussion E9-10</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16641948</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2008 Jan 17;358(3):261-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18199865</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2006 Jan 1;42(1):14-20</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16323086</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Pathol. 2008 May;172(5):1155-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18403604</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2007 Dec;13(12):1871-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18258038</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2004 Sep;78(17):8951-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15308692</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2006 Jan;12(1):3-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16494709</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20949-54</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18093945</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2008 Jul 10;454(7201):137</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18615026</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2001 Oct;75(20):9679-86</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11559800</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2008 Feb;82(4):1798-807</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18077726</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2006 Apr 21;312(5772):399</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16556800</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 1970 Nov 28;228(5274):857</Citation>
<ArticleIdList><ArticleId IdType="pubmed">5477012</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 2001 Jun;82(Pt 6):1397-406</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11369884</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2008 Jul;4(7):e1000102</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18617994</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2006 Mar 24;311(5768):1692</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16556809</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Dis. 2008 Jan 1;197(1):18-24</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18171280</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vaccine. 2002 Aug 19;20(25-26):3068-87</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12163258</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2007 Jan 5;315(5808):30-3</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17204617</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2008 Mar;46(3):1067-75</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18199784</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2006 Jul;12(7):1132-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16836834</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2006 Apr 27;440(7088):E9; discussion E9-10</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16641950</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2007 Apr 15;44(8):1084-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17366454</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 1985 Dec;147(2):287-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2416114</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2005 Oct 6;437(7060):889-93</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16208372</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 1995 May;76 ( Pt 5):1247-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7730809</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2008 Jan;82(1):220-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17942562</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 1991 Jul;183(1):61-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2053297</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
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The pig as a mixing vessel for influenza viruses: Human and veterinary implications.

The pig as a mixing vessel for influenza viruses: Human and veterinary implications.

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