Updated Values for Molecular Diagnosis for Highly Pathogenic Avian Influenza Virus
Identifieur interne : 000E27 ( Pmc/Curation ); précédent : 000E26; suivant : 000E28Updated Values for Molecular Diagnosis for Highly Pathogenic Avian Influenza Virus
Auteurs : Akira Sakurai ; Futoshi ShibasakiSource :
- Viruses [ 1999-4915 ] ; 2012.
Abstract
Highly pathogenic avian influenza (HPAI) viruses of the H5N1 strain pose a pandemic threat. H5N1 strain virus is extremely lethal and contagious for poultry. Even though mortality is 59% in infected humans, these viruses do not spread efficiently between humans. In 1997, an outbreak of H5N1 strain with human cases occurred in Hong Kong. This event highlighted the need for rapid identification and subtyping of influenza A viruses (IAV), not only to facilitate surveillance of the pandemic potential of avian IAV, but also to improve the control and treatment of infected patients. Molecular diagnosis has played a key role in the detection and typing of IAV in recent years, spurred by rapid advances in technologies for detection and characterization of viral RNAs and proteins. Such technologies, which include immunochromatography, quantitative real-time PCR, super high-speed real-time PCR, and isothermal DNA amplification, are expected to contribute to faster and easier diagnosis and typing of IAV.
Url:
DOI: 10.3390/v4081235
PubMed: 23012622
PubMed Central: 3446759
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Updated Values for Molecular Diagnosis for Highly Pathogenic Avian Influenza Virus</title><author><name sortKey="Sakurai, Akira" sort="Sakurai, Akira" uniqKey="Sakurai A" first="Akira" last="Sakurai">Akira Sakurai</name></author><author><name sortKey="Shibasaki, Futoshi" sort="Shibasaki, Futoshi" uniqKey="Shibasaki F" first="Futoshi" last="Shibasaki">Futoshi Shibasaki</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23012622</idno><idno type="pmc">3446759</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446759</idno><idno type="RBID">PMC:3446759</idno><idno type="doi">10.3390/v4081235</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">000E27</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000E27</idno><idno type="wicri:Area/Pmc/Curation">000E27</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000E27</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Updated Values for Molecular Diagnosis for Highly Pathogenic Avian Influenza Virus</title><author><name sortKey="Sakurai, Akira" sort="Sakurai, Akira" uniqKey="Sakurai A" first="Akira" last="Sakurai">Akira Sakurai</name></author><author><name sortKey="Shibasaki, Futoshi" sort="Shibasaki, Futoshi" uniqKey="Shibasaki F" first="Futoshi" last="Shibasaki">Futoshi Shibasaki</name></author></analytic><series><title level="j">Viruses</title><idno type="eISSN">1999-4915</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Highly pathogenic avian influenza (HPAI) viruses of the H5N1 strain pose a pandemic threat. H5N1 strain virus is extremely lethal and contagious for poultry. Even though mortality is 59% in infected humans, these viruses do not spread efficiently between humans. In 1997, an outbreak of H5N1 strain with human cases occurred in Hong Kong. This event highlighted the need for rapid identification and subtyping of influenza A viruses (IAV), not only to facilitate surveillance of the pandemic potential of avian IAV, but also to improve the control and treatment of infected patients. Molecular diagnosis has played a key role in the detection and typing of IAV in recent years, spurred by rapid advances in technologies for detection and characterization of viral RNAs and proteins. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Viruses</journal-id><journal-id journal-id-type="iso-abbrev">Viruses</journal-id><journal-id journal-id-type="publisher-id">viruses</journal-id><journal-title-group><journal-title>Viruses</journal-title></journal-title-group><issn pub-type="epub">1999-4915</issn><publisher><publisher-name>MDPI</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">23012622</article-id><article-id pub-id-type="pmc">3446759</article-id><article-id pub-id-type="doi">10.3390/v4081235</article-id><article-id pub-id-type="publisher-id">viruses-04-01235</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Updated Values for Molecular Diagnosis for Highly Pathogenic Avian Influenza Virus</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Sakurai</surname><given-names>Akira</given-names></name></contrib><contrib contrib-type="author"><name><surname>Shibasaki</surname><given-names>Futoshi</given-names></name><xref rid="c1-viruses-04-01235" ref-type="corresp">*</xref></contrib></contrib-group><aff id="af1-viruses-04-01235">Department of Molecular Medical Research, Tokyo Metropolitan Institute of Medical Science, 2-1-6, Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan; Email:<email>sakurai-ak@igakuken.or.jp</email> (A.S.);<email>shibasaki-ft@igakuken.or.jp</email> (F.S.)</aff><author-notes><corresp id="c1-viruses-04-01235"><label>*</label> Author to whom correspondence should be addressed; Email: <email>shibasaki-ft@igakuken.or.jp</email> (F.S.); Tel.: +81-3-5316-3299; Fax: +81-3-5316-3173</corresp></author-notes><pub-date pub-type="epub"><day>07</day><month>8</month><year>2012</year></pub-date><pub-date pub-type="collection"><month>8</month><year>2012</year></pub-date><volume>4</volume><issue>8</issue><fpage>1235</fpage><lpage>1257</lpage><history><date date-type="received"><day>20</day><month>7</month><year>2012</year></date><date date-type="rev-recd"><day>31</day><month>7</month><year>2012</year></date><date date-type="accepted"><day>03</day><month>8</month><year>2012</year></date></history><permissions><copyright-statement>© 2012 by the authors; licensee MDPI, Basel, Switzerland.</copyright-statement><copyright-year>2012</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/3.0/"><license-p><pmc-comment>CREATIVE COMMONS</pmc-comment>This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/3.0/">http://creativecommons.org/licenses/by/3.0/</ext-link>).</license-p></license></permissions><abstract><p>Highly pathogenic avian influenza (HPAI) viruses of the H5N1 strain pose a pandemic threat. H5N1 strain virus is extremely lethal and contagious for poultry. Even though mortality is 59% in infected humans, these viruses do not spread efficiently between humans. In 1997, an outbreak of H5N1 strain with human cases occurred in Hong Kong. This event highlighted the need for rapid identification and subtyping of influenza A viruses (IAV), not only to facilitate surveillance of the pandemic potential of avian IAV, but also to improve the control and treatment of infected patients. Molecular diagnosis has played a key role in the detection and typing of IAV in recent years, spurred by rapid advances in technologies for detection and characterization of viral RNAs and proteins. Such technologies, which include immunochromatography, quantitative real-time PCR, super high-speed real-time PCR, and isothermal DNA amplification, are expected to contribute to faster and easier diagnosis and typing of IAV.</p></abstract><kwd-group><kwd>influenza virus</kwd><kwd>highly pathogenic avian influenza virus H5N1</kwd><kwd>molecular diagnosis </kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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