Potency of an inactivated influenza vaccine prepared from A/duck/Hokkaido/162/2013 (H2N1) against a challenge with A/swine/Missouri/2124514/2006 (H2N3) in mice
Identifieur interne : 000A18 ( Pmc/Curation ); précédent : 000A17; suivant : 000A19Potency of an inactivated influenza vaccine prepared from A/duck/Hokkaido/162/2013 (H2N1) against a challenge with A/swine/Missouri/2124514/2006 (H2N3) in mice
Auteurs : Mizuho Suzuki ; Masatoshi Okamatsu ; Takahiro Hiono ; Keita Matsuno ; Yoshihiro SakodaSource :
- The Journal of Veterinary Medical Science [ 0916-7250 ] ; 2017.
Abstract
H2N2 influenza virus caused a pandemic starting in 1957 but has not been detected in humans since 1968. Thus, most people are immunologically naive to viruses of the H2 subtype. In contrast, H2 influenza viruses are continually isolated from wild birds, and H2N3 viruses were isolated from pigs in 2006. H2 influenza viruses could cause a pandemic if re-introduced into humans. In the present study, a vaccine against H2 influenza was prepared as an effective control measure against a future human pandemic. A/duck/Hokkaido/162/2013 (H2N1), which showed broad antigenic cross-reactivity, was selected from the candidate H2 influenza viruses recently isolated from wild birds in Asian countries. Sufficient neutralizing antibodies against homologous and heterologous viruses were induced in mice after two subcutaneous injections of the inactivated whole virus particle vaccine. The inactivated vaccine induced protective immunity sufficient to reduce the impact of challenges with A/swine/Missouri/2124514/2006 (H2N3). This study demonstrates that the inactivated whole virus particle vaccine prepared from an influenza virus library would be useful against a future H2 influenza pandemic.
Url:
DOI: 10.1292/jvms.17-0312
PubMed: 28993601
PubMed Central: 5709558
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000A18
Links to Exploration step
PMC:5709558Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Potency of an inactivated influenza vaccine prepared from A/duck/Hokkaido/162/2013 (H2N1) against a challenge with A/swine/Missouri/2124514/2006 (H2N3) in mice</title><author><name sortKey="Suzuki, Mizuho" sort="Suzuki, Mizuho" uniqKey="Suzuki M" first="Mizuho" last="Suzuki">Mizuho Suzuki</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Okamatsu, Masatoshi" sort="Okamatsu, Masatoshi" uniqKey="Okamatsu M" first="Masatoshi" last="Okamatsu">Masatoshi Okamatsu</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Hiono, Takahiro" sort="Hiono, Takahiro" uniqKey="Hiono T" first="Takahiro" last="Hiono">Takahiro Hiono</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Matsuno, Keita" sort="Matsuno, Keita" uniqKey="Matsuno K" first="Keita" last="Matsuno">Keita Matsuno</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Sakoda, Yoshihiro" sort="Sakoda, Yoshihiro" uniqKey="Sakoda Y" first="Yoshihiro" last="Sakoda">Yoshihiro Sakoda</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">28993601</idno><idno type="pmc">5709558</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709558</idno><idno type="RBID">PMC:5709558</idno><idno type="doi">10.1292/jvms.17-0312</idno><date when="2017">2017</date><idno type="wicri:Area/Pmc/Corpus">000A18</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000A18</idno><idno type="wicri:Area/Pmc/Curation">000A18</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000A18</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Potency of an inactivated influenza vaccine prepared from A/duck/Hokkaido/162/2013 (H2N1) against a challenge with A/swine/Missouri/2124514/2006 (H2N3) in mice</title><author><name sortKey="Suzuki, Mizuho" sort="Suzuki, Mizuho" uniqKey="Suzuki M" first="Mizuho" last="Suzuki">Mizuho Suzuki</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Okamatsu, Masatoshi" sort="Okamatsu, Masatoshi" uniqKey="Okamatsu M" first="Masatoshi" last="Okamatsu">Masatoshi Okamatsu</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Hiono, Takahiro" sort="Hiono, Takahiro" uniqKey="Hiono T" first="Takahiro" last="Hiono">Takahiro Hiono</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Matsuno, Keita" sort="Matsuno, Keita" uniqKey="Matsuno K" first="Keita" last="Matsuno">Keita Matsuno</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Sakoda, Yoshihiro" sort="Sakoda, Yoshihiro" uniqKey="Sakoda Y" first="Yoshihiro" last="Sakoda">Yoshihiro Sakoda</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author></analytic><series><title level="j">The Journal of Veterinary Medical Science</title><idno type="ISSN">0916-7250</idno><idno type="eISSN">1347-7439</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>H2N2 influenza virus caused a pandemic starting in 1957 but has not been detected in humans since 1968. Thus, most people are immunologically naive to viruses of the H2 subtype. In contrast, H2 influenza viruses are continually
isolated from wild birds, and H2N3 viruses were isolated from pigs in 2006. H2 influenza viruses could cause a pandemic if re-introduced into humans. In the present study, a vaccine against H2 influenza was prepared as an
effective control measure against a future human pandemic. A/duck/Hokkaido/162/2013 (H2N1), which showed broad antigenic cross-reactivity, was selected from the candidate H2 influenza viruses recently isolated from wild birds in
Asian countries. Sufficient neutralizing antibodies against homologous and heterologous viruses were induced in mice after two subcutaneous injections of the inactivated whole virus particle vaccine. The inactivated vaccine
induced protective immunity sufficient to reduce the impact of challenges with A/swine/Missouri/2124514/2006 (H2N3). This study demonstrates that the inactivated whole virus particle vaccine prepared from an influenza virus
library would be useful against a future H2 influenza pandemic.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Arikata, M" uniqKey="Arikata M">M. Arikata</name></author><author><name sortKey="Itoh, Y" uniqKey="Itoh Y">Y. Itoh</name></author><author><name sortKey="Okamatsu, M" uniqKey="Okamatsu M">M. Okamatsu</name></author><author><name sortKey="Maeda, T" uniqKey="Maeda T">T. Maeda</name></author><author><name sortKey="Shiina, T" uniqKey="Shiina T">T. Shiina</name></author><author><name sortKey="Tanaka, K" uniqKey="Tanaka K">K. Tanaka</name></author><author><name sortKey="Suzuki, S" uniqKey="Suzuki S">S. Suzuki</name></author><author><name sortKey="Nakayama, M" uniqKey="Nakayama M">M. Nakayama</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y. Sakoda</name></author><author><name sortKey="Ishigaki, H" uniqKey="Ishigaki H">H. Ishigaki</name></author><author><name sortKey="Takada, A" uniqKey="Takada A">A. Takada</name></author><author><name sortKey="Ishida, H" uniqKey="Ishida H">H. Ishida</name></author><author><name sortKey="Soda, K" uniqKey="Soda K">K. Soda</name></author><author><name sortKey="Pham, V L" uniqKey="Pham V">V. L. Pham</name></author><author><name sortKey="Tsuchiya, H" uniqKey="Tsuchiya H">H. Tsuchiya</name></author><author><name sortKey="Nakamura, S" uniqKey="Nakamura S">S. Nakamura</name></author><author><name sortKey="Torii, R" uniqKey="Torii R">R. Torii</name></author><author><name sortKey="Shimizu, T" uniqKey="Shimizu T">T. Shimizu</name></author><author><name sortKey="Inoko, H" uniqKey="Inoko H">H. Inoko</name></author><author><name sortKey="Ohkubo, I" uniqKey="Ohkubo I">I. Ohkubo</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H. Kida</name></author><author><name sortKey="Ogasawara, K" uniqKey="Ogasawara K">K. Ogasawara</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, G L" uniqKey="Chen G">G. L. Chen</name></author><author><name sortKey="Lamirande, E W" uniqKey="Lamirande E">E. W. Lamirande</name></author><author><name sortKey="Jin, H" uniqKey="Jin H">H. Jin</name></author><author><name sortKey="Kemble, G" uniqKey="Kemble G">G. Kemble</name></author><author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K. Subbarao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, G L" uniqKey="Chen G">G. L. Chen</name></author><author><name sortKey="Lamirande, E W" uniqKey="Lamirande E">E. W. Lamirande</name></author><author><name sortKey="Cheng, X" uniqKey="Cheng X">X. Cheng</name></author><author><name sortKey="Torres Velez, F" uniqKey="Torres Velez F">F. Torres-Velez</name></author><author><name sortKey="Orandle, M" uniqKey="Orandle M">M. Orandle</name></author><author><name sortKey="Jin, H" uniqKey="Jin H">H. Jin</name></author><author><name sortKey="Kemble, G" uniqKey="Kemble G">G. Kemble</name></author><author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K. Subbarao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chu, D H" uniqKey="Chu D">D. H. Chu</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y. Sakoda</name></author><author><name sortKey="Nishi, T" uniqKey="Nishi T">T. Nishi</name></author><author><name sortKey="Hiono, T" uniqKey="Hiono T">T. Hiono</name></author><author><name sortKey="Shichinohe, S" uniqKey="Shichinohe S">S. Shichinohe</name></author><author><name sortKey="Okamatsu, M" uniqKey="Okamatsu M">M. Okamatsu</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H. Kida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Govorkova, E A" uniqKey="Govorkova E">E. A. Govorkova</name></author><author><name sortKey="Smirnov Yua" uniqKey="Smirnov Yua">Smirnov YuA</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hall, J S" uniqKey="Hall J">J. S. Hall</name></author><author><name sortKey="Hallgrimsson, G T" uniqKey="Hallgrimsson G">G. T. Hallgrimsson</name></author><author><name sortKey="Suwannanarn, K" uniqKey="Suwannanarn K">K. Suwannanarn</name></author><author><name sortKey="Sreevatsen, S" uniqKey="Sreevatsen S">S. Sreevatsen</name></author><author><name sortKey="Ip, H S" uniqKey="Ip H">H. S. Ip</name></author><author><name sortKey="Magnusdottir, E" uniqKey="Magnusdottir E">E. Magnusdottir</name></author><author><name sortKey="Teslaa, J L" uniqKey="Teslaa J">J. L. TeSlaa</name></author><author><name sortKey="Nashold, S W" uniqKey="Nashold S">S. W. Nashold</name></author><author><name sortKey="Dusek, R J" uniqKey="Dusek R">R. J. Dusek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hiono, T" uniqKey="Hiono T">T. Hiono</name></author><author><name sortKey="Ohkawara, A" uniqKey="Ohkawara A">A. Ohkawara</name></author><author><name sortKey="Ogasawara, K" uniqKey="Ogasawara K">K. Ogasawara</name></author><author><name sortKey="Okamatsu, M" uniqKey="Okamatsu M">M. Okamatsu</name></author><author><name sortKey="Tamura, T" uniqKey="Tamura T">T. Tamura</name></author><author><name sortKey="Chu, D H" uniqKey="Chu D">D. H. Chu</name></author><author><name sortKey="Suzuki, M" uniqKey="Suzuki M">M. Suzuki</name></author><author><name sortKey="Kuribayashi, S" uniqKey="Kuribayashi S">S. Kuribayashi</name></author><author><name sortKey="Shichinohe, S" uniqKey="Shichinohe S">S. Shichinohe</name></author><author><name sortKey="Takada, A" uniqKey="Takada A">A. Takada</name></author><author><name sortKey="Ogawa, H" uniqKey="Ogawa H">H. Ogawa</name></author><author><name sortKey="Yoshida, R" uniqKey="Yoshida R">R. Yoshida</name></author><author><name sortKey="Miyamoto, H" uniqKey="Miyamoto H">H. Miyamoto</name></author><author><name sortKey="Nao, N" uniqKey="Nao N">N. Nao</name></author><author><name sortKey="Furuyama, W" uniqKey="Furuyama W">W. Furuyama</name></author><author><name sortKey="Maruyama, J" uniqKey="Maruyama J">J. Maruyama</name></author><author><name sortKey="Eguchi, N" uniqKey="Eguchi N">N. Eguchi</name></author><author><name sortKey="Ulziibat, G" uniqKey="Ulziibat G">G. Ulziibat</name></author><author><name sortKey="Enkhbold, B" uniqKey="Enkhbold B">B. Enkhbold</name></author><author><name sortKey="Shatar, M" uniqKey="Shatar M">M. Shatar</name></author><author><name sortKey="Jargalsaikhan, T" uniqKey="Jargalsaikhan T">T. Jargalsaikhan</name></author><author><name sortKey="Byambadorj, S" uniqKey="Byambadorj S">S. Byambadorj</name></author><author><name sortKey="Damdinjav, B" uniqKey="Damdinjav B">B. Damdinjav</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y. Sakoda</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H. Kida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoffmann, E" uniqKey="Hoffmann E">E. Hoffmann</name></author><author><name sortKey="Stech, J" uniqKey="Stech J">J. Stech</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Webster, R G" uniqKey="Webster R">R. G. Webster</name></author><author><name sortKey="Perez, D R" uniqKey="Perez D">D. R. Perez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hovden, A O" uniqKey="Hovden A">A. O. Hovden</name></author><author><name sortKey="Brokstad, K A" uniqKey="Brokstad K">K. A. Brokstad</name></author><author><name sortKey="Major, D" uniqKey="Major D">D. Major</name></author><author><name sortKey="Wood, J" uniqKey="Wood J">J. Wood</name></author><author><name sortKey="Haaheim, L R" uniqKey="Haaheim L">L. R. Haaheim</name></author><author><name sortKey="Cox, R J" uniqKey="Cox R">R. J. Cox</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ito, T" uniqKey="Ito T">T. Ito</name></author><author><name sortKey="Okazaki, K" uniqKey="Okazaki K">K. Okazaki</name></author><author><name sortKey="Kawaoka, Y" uniqKey="Kawaoka Y">Y. Kawaoka</name></author><author><name sortKey="Takada, A" uniqKey="Takada A">A. Takada</name></author><author><name sortKey="Webster, R G" uniqKey="Webster R">R. G. Webster</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H. Kida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Itoh, Y" uniqKey="Itoh Y">Y. Itoh</name></author><author><name sortKey="Ozaki, H" uniqKey="Ozaki H">H. Ozaki</name></author><author><name sortKey="Ishigaki, H" uniqKey="Ishigaki H">H. Ishigaki</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y. Sakoda</name></author><author><name sortKey="Nagata, T" uniqKey="Nagata T">T. Nagata</name></author><author><name sortKey="Soda, K" uniqKey="Soda K">K. Soda</name></author><author><name sortKey="Isoda, N" uniqKey="Isoda N">N. Isoda</name></author><author><name sortKey="Miyake, T" uniqKey="Miyake T">T. Miyake</name></author><author><name sortKey="Ishida, H" uniqKey="Ishida H">H. Ishida</name></author><author><name sortKey="Okamoto, K" uniqKey="Okamoto K">K. Okamoto</name></author><author><name sortKey="Nakayama, M" uniqKey="Nakayama M">M. Nakayama</name></author><author><name sortKey="Tsuchiya, H" uniqKey="Tsuchiya H">H. Tsuchiya</name></author><author><name sortKey="Torii, R" uniqKey="Torii R">R. Torii</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H. Kida</name></author><author><name sortKey="Ogasawara, K" uniqKey="Ogasawara K">K. Ogasawara</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Itoh, Y" uniqKey="Itoh Y">Y. Itoh</name></author><author><name sortKey="Ozaki, H" uniqKey="Ozaki H">H. Ozaki</name></author><author><name sortKey="Tsuchiya, H" uniqKey="Tsuchiya H">H. Tsuchiya</name></author><author><name sortKey="Okamoto, K" uniqKey="Okamoto K">K. Okamoto</name></author><author><name sortKey="Torii, R" uniqKey="Torii R">R. Torii</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y. Sakoda</name></author><author><name sortKey="Kawaoka, Y" uniqKey="Kawaoka Y">Y. Kawaoka</name></author><author><name sortKey="Ogasawara, K" uniqKey="Ogasawara K">K. Ogasawara</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H. Kida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jones, J C" uniqKey="Jones J">J. C. Jones</name></author><author><name sortKey="Baranovich, T" uniqKey="Baranovich T">T. Baranovich</name></author><author><name sortKey="Marathe, B M" uniqKey="Marathe B">B. M. Marathe</name></author><author><name sortKey="Danner, A F" uniqKey="Danner A">A. F. Danner</name></author><author><name sortKey="Seiler, J P" uniqKey="Seiler J">J. P. Seiler</name></author><author><name sortKey="Franks, J" uniqKey="Franks J">J. Franks</name></author><author><name sortKey="Govorkova, E A" uniqKey="Govorkova E">E. A. Govorkova</name></author><author><name sortKey="Krauss, S" uniqKey="Krauss S">S. Krauss</name></author><author><name sortKey="Webster, R G" uniqKey="Webster R">R. G. Webster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kaverin, N V" uniqKey="Kaverin N">N. V. Kaverin</name></author><author><name sortKey="Smirnov, Y A" uniqKey="Smirnov Y">Y. A. Smirnov</name></author><author><name sortKey="Govorkova, E A" uniqKey="Govorkova E">E. A. Govorkova</name></author><author><name sortKey="Rudneva, I A" uniqKey="Rudneva I">I. A. Rudneva</name></author><author><name sortKey="Gitelman, A K" uniqKey="Gitelman A">A. K. Gitelman</name></author><author><name sortKey="Lipatov, A S" uniqKey="Lipatov A">A. S. Lipatov</name></author><author><name sortKey="Varich, N L" uniqKey="Varich N">N. L. Varich</name></author><author><name sortKey="Yamnikova, S S" uniqKey="Yamnikova S">S. S. Yamnikova</name></author><author><name sortKey="Makarova, N V" uniqKey="Makarova N">N. V. Makarova</name></author><author><name sortKey="Webster, R G" uniqKey="Webster R">R. G. Webster</name></author><author><name sortKey="Lvov, D K" uniqKey="Lvov D">D. K. Lvov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kida, H" uniqKey="Kida H">H. Kida</name></author><author><name sortKey="Brown, L E" uniqKey="Brown L">L. E. Brown</name></author><author><name sortKey="Webster, R G" uniqKey="Webster R">R. G. Webster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kishida, N" uniqKey="Kishida N">N. Kishida</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y. Sakoda</name></author><author><name sortKey="Shiromoto, M" uniqKey="Shiromoto M">M. Shiromoto</name></author><author><name sortKey="Bai, G R" uniqKey="Bai G">G. R. Bai</name></author><author><name sortKey="Isoda, N" uniqKey="Isoda N">N. Isoda</name></author><author><name sortKey="Takada, A" uniqKey="Takada A">A. Takada</name></author><author><name sortKey="Laver, G" uniqKey="Laver G">G. Laver</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H. Kida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krauss, S" uniqKey="Krauss S">S. Krauss</name></author><author><name sortKey="Obert, C A" uniqKey="Obert C">C. A. Obert</name></author><author><name sortKey="Franks, J" uniqKey="Franks J">J. Franks</name></author><author><name sortKey="Walker, D" uniqKey="Walker D">D. Walker</name></author><author><name sortKey="Jones, K" uniqKey="Jones K">K. Jones</name></author><author><name sortKey="Seiler, P" uniqKey="Seiler P">P. Seiler</name></author><author><name sortKey="Niles, L" uniqKey="Niles L">L. Niles</name></author><author><name sortKey="Pryor, S P" uniqKey="Pryor S">S. P. Pryor</name></author><author><name sortKey="Obenauer, J C" uniqKey="Obenauer J">J. C. Obenauer</name></author><author><name sortKey="Naeve, C W" uniqKey="Naeve C">C. W. Naeve</name></author><author><name sortKey="Widjaja, L" uniqKey="Widjaja L">L. Widjaja</name></author><author><name sortKey="Webby, R J" uniqKey="Webby R">R. J. Webby</name></author><author><name sortKey="Webster, R G" uniqKey="Webster R">R. G. Webster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lenny, B J" uniqKey="Lenny B">B. J. Lenny</name></author><author><name sortKey="Sonnberg, S" uniqKey="Sonnberg S">S. Sonnberg</name></author><author><name sortKey="Danner, A F" uniqKey="Danner A">A. F. Danner</name></author><author><name sortKey="Friedman, K" uniqKey="Friedman K">K. Friedman</name></author><author><name sortKey="Webby, R J" uniqKey="Webby R">R. J. Webby</name></author><author><name sortKey="Webster, R G" uniqKey="Webster R">R. G. Webster</name></author><author><name sortKey="Jones, J C" uniqKey="Jones J">J. C. Jones</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ma, W" uniqKey="Ma W">W. Ma</name></author><author><name sortKey="Vincent, A L" uniqKey="Vincent A">A. L. Vincent</name></author><author><name sortKey="Gramer, M R" uniqKey="Gramer M">M. R. Gramer</name></author><author><name sortKey="Brockwell, C B" uniqKey="Brockwell C">C. B. Brockwell</name></author><author><name sortKey="Lager, K M" uniqKey="Lager K">K. M. Lager</name></author><author><name sortKey="Janke, B H" uniqKey="Janke B">B. H. Janke</name></author><author><name sortKey="Gauger, P C" uniqKey="Gauger P">P. C. Gauger</name></author><author><name sortKey="Patnayak, D P" uniqKey="Patnayak D">D. P. Patnayak</name></author><author><name sortKey="Webby, R J" uniqKey="Webby R">R. J. Webby</name></author><author><name sortKey="Richt, J A" uniqKey="Richt J">J. A. Richt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nabel, G J" uniqKey="Nabel G">G. J. Nabel</name></author><author><name sortKey="Wei, C J" uniqKey="Wei C">C. J. Wei</name></author><author><name sortKey="Ledgerwood, J E" uniqKey="Ledgerwood J">J. E. Ledgerwood</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nishi, T" uniqKey="Nishi T">T. Nishi</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y. Sakoda</name></author><author><name sortKey="Okamatsu, M" uniqKey="Okamatsu M">M. Okamatsu</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H. Kida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nomura, N" uniqKey="Nomura N">N. Nomura</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y. Sakoda</name></author><author><name sortKey="Soda, K" uniqKey="Soda K">K. Soda</name></author><author><name sortKey="Okamatsu, M" uniqKey="Okamatsu M">M. Okamatsu</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H. Kida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Okamatsu, M" uniqKey="Okamatsu M">M. Okamatsu</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y. Sakoda</name></author><author><name sortKey="Hiono, T" uniqKey="Hiono T">T. Hiono</name></author><author><name sortKey="Yamamoto, N" uniqKey="Yamamoto N">N. Yamamoto</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H. Kida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Piaggio, A J" uniqKey="Piaggio A">A. J. Piaggio</name></author><author><name sortKey="Shriner, S A" uniqKey="Shriner S">S. A. Shriner</name></author><author><name sortKey="Vandalen, K K" uniqKey="Vandalen K">K. K. VanDalen</name></author><author><name sortKey="Franklin, A B" uniqKey="Franklin A">A. B. Franklin</name></author><author><name sortKey="Anderson, T D" uniqKey="Anderson T">T. D. Anderson</name></author><author><name sortKey="Kolokotronis, S O" uniqKey="Kolokotronis S">S. O. Kolokotronis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sakabe, S" uniqKey="Sakabe S">S. Sakabe</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y. Sakoda</name></author><author><name sortKey="Haraguchi, Y" uniqKey="Haraguchi Y">Y. Haraguchi</name></author><author><name sortKey="Isoda, N" uniqKey="Isoda N">N. Isoda</name></author><author><name sortKey="Soda, K" uniqKey="Soda K">K. Soda</name></author><author><name sortKey="Takakuwa, H" uniqKey="Takakuwa H">H. Takakuwa</name></author><author><name sortKey="Saijo, K" uniqKey="Saijo K">K. Saijo</name></author><author><name sortKey="Sawata, A" uniqKey="Sawata A">A. Sawata</name></author><author><name sortKey="Kume, K" uniqKey="Kume K">K. Kume</name></author><author><name sortKey="Hagiwara, J" uniqKey="Hagiwara J">J. Hagiwara</name></author><author><name sortKey="Tuchiya, K" uniqKey="Tuchiya K">K. Tuchiya</name></author><author><name sortKey="Lin, Z" uniqKey="Lin Z">Z. Lin</name></author><author><name sortKey="Sakamoto, R" uniqKey="Sakamoto R">R. Sakamoto</name></author><author><name sortKey="Imamura, T" uniqKey="Imamura T">T. Imamura</name></author><author><name sortKey="Sasaki, T" uniqKey="Sasaki T">T. Sasaki</name></author><author><name sortKey="Kokumai, N" uniqKey="Kokumai N">N. Kokumai</name></author><author><name sortKey="Kawaoka, Y" uniqKey="Kawaoka Y">Y. Kawaoka</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H. Kida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sch Fer, J R" uniqKey="Sch Fer J">J. R. Schäfer</name></author><author><name sortKey="Kawaoka, Y" uniqKey="Kawaoka Y">Y. Kawaoka</name></author><author><name sortKey="Bean, W J" uniqKey="Bean W">W. J. Bean</name></author><author><name sortKey="Suss, J" uniqKey="Suss J">J. Süss</name></author><author><name sortKey="Senne, D" uniqKey="Senne D">D. Senne</name></author><author><name sortKey="Webster, R G" uniqKey="Webster R">R. G. Webster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Simonsen, L" uniqKey="Simonsen L">L. Simonsen</name></author><author><name sortKey="Clarke, M J" uniqKey="Clarke M">M. J. Clarke</name></author><author><name sortKey="Schonberger, L B" uniqKey="Schonberger L">L. B. Schonberger</name></author><author><name sortKey="Arden, N H" uniqKey="Arden N">N. H. Arden</name></author><author><name sortKey="Cox, N J" uniqKey="Cox N">N. J. Cox</name></author><author><name sortKey="Fukuda, K" uniqKey="Fukuda K">K. Fukuda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, H" uniqKey="Wu H">H. Wu</name></author><author><name sortKey="Peng, X" uniqKey="Peng X">X. Peng</name></author><author><name sortKey="Peng, X" uniqKey="Peng X">X. Peng</name></author><author><name sortKey="Cheng, L" uniqKey="Cheng L">L. Cheng</name></author><author><name sortKey="Wu, N" uniqKey="Wu N">N. Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yamamoto, N" uniqKey="Yamamoto N">N. Yamamoto</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y. Sakoda</name></author><author><name sortKey="Motoshima, M" uniqKey="Motoshima M">M. Motoshima</name></author><author><name sortKey="Yoshino, F" uniqKey="Yoshino F">F. Yoshino</name></author><author><name sortKey="Soda, K" uniqKey="Soda K">K. Soda</name></author><author><name sortKey="Okamatsu, M" uniqKey="Okamatsu M">M. Okamatsu</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H. Kida</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Vet Med Sci</journal-id><journal-id journal-id-type="iso-abbrev">J. Vet. Med. Sci</journal-id><journal-id journal-id-type="publisher-id">JVMS</journal-id><journal-title-group><journal-title>The Journal of Veterinary Medical Science</journal-title></journal-title-group><issn pub-type="ppub">0916-7250</issn><issn pub-type="epub">1347-7439</issn><publisher><publisher-name>The Japanese Society of Veterinary Science</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">28993601</article-id><article-id pub-id-type="pmc">5709558</article-id><article-id pub-id-type="publisher-id">17-0312</article-id><article-id pub-id-type="doi">10.1292/jvms.17-0312</article-id><article-categories><subj-group subj-group-type="heading"><subject>Virology</subject><subj-group><subject>Full Paper</subject></subj-group></subj-group></article-categories><title-group><article-title>Potency of an inactivated influenza vaccine prepared from A/duck/Hokkaido/162/2013 (H2N1) against a challenge with A/swine/Missouri/2124514/2006 (H2N3) in mice</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>SUZUKI</surname><given-names>Mizuho</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>OKAMATSU</surname><given-names>Masatoshi</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>HIONO</surname><given-names>Takahiro</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>MATSUNO</surname><given-names>Keita</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>SAKODA</surname><given-names>Yoshihiro</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref rid="cor1" ref-type="corresp"><sup>*</sup></xref></contrib><aff id="aff1"><label>1)</label>Laboratory of Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita-ku, Sapporo 060-0818, Japan</aff><aff id="aff2"><label>2)</label>Global Station for Zoonosis Control, Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818, Japan</aff></contrib-group><author-notes><corresp id="cor1"><label>*</label>Correspondence to: Sakoda, Y.: <email xlink:href="sakoda@vetmed.hokudai.ac.jp">sakoda@vetmed.hokudai.ac.jp</email></corresp></author-notes><pub-date pub-type="epub"><day>07</day><month>10</month><year>2017</year></pub-date><pub-date pub-type="ppub"><month>11</month><year>2017</year></pub-date><volume>79</volume><issue>11</issue><fpage>1815</fpage><lpage>1821</lpage><history><date date-type="received"><day>06</day><month>6</month><year>2017</year></date><date date-type="accepted"><day>02</day><month>9</month><year>2017</year></date></history><permissions><copyright-statement>©2017 The Japanese Society of Veterinary Science</copyright-statement><copyright-year>2017</copyright-year><license license-type="open-access"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by-nc-nd/4.0/"> https://creativecommons.org/licenses/by-nc-nd/4.0/</ext-link>)</license-p></license></permissions><abstract><p>H2N2 influenza virus caused a pandemic starting in 1957 but has not been detected in humans since 1968. Thus, most people are immunologically naive to viruses of the H2 subtype. In contrast, H2 influenza viruses are continually
isolated from wild birds, and H2N3 viruses were isolated from pigs in 2006. H2 influenza viruses could cause a pandemic if re-introduced into humans. In the present study, a vaccine against H2 influenza was prepared as an
effective control measure against a future human pandemic. A/duck/Hokkaido/162/2013 (H2N1), which showed broad antigenic cross-reactivity, was selected from the candidate H2 influenza viruses recently isolated from wild birds in
Asian countries. Sufficient neutralizing antibodies against homologous and heterologous viruses were induced in mice after two subcutaneous injections of the inactivated whole virus particle vaccine. The inactivated vaccine
induced protective immunity sufficient to reduce the impact of challenges with A/swine/Missouri/2124514/2006 (H2N3). This study demonstrates that the inactivated whole virus particle vaccine prepared from an influenza virus
library would be useful against a future H2 influenza pandemic.</p></abstract><kwd-group><kwd>antigenicity</kwd><kwd>H2 influenza</kwd><kwd>pre-pandemic</kwd><kwd>vaccine</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Pmc/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A18 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd -nk 000A18 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= Pmc
|étape= Curation
|type= RBID
|clé= PMC:5709558
|texte= Potency of an inactivated influenza vaccine prepared from A/duck/Hokkaido/162/2013 (H2N1) against a challenge with A/swine/Missouri/2124514/2006 (H2N3) in mice
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Curation/RBID.i -Sk "pubmed:28993601" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd \
| NlmPubMed2Wicri -a H2N2V1
| This area was generated with Dilib version V0.6.33. |  |