Connecting the study of wild influenza with the potential for pandemic disease
Identifieur interne : 000808 ( Pmc/Corpus ); précédent : 000807; suivant : 000809Connecting the study of wild influenza with the potential for pandemic disease
Auteurs : Jonathan Runstadler ; Nichola Hill ; Islam T. M. Hussein ; Wendy Puryear ; Mandy KeoghSource :
- Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [ 1567-1348 ] ; 2013.
Abstract
Continuing outbreaks of pathogenic (H5N1) and pandemic (SOIVH1N1) influenza have underscored the need to understand the origin, characteristics, and evolution of novel influenza A virus (IAV) variants that pose a threat to human health. In the last 4–5 years, focus has been placed on the organization of large-scale surveillance programs to examine the phylogenetics of avian influenza virus (AIV) and host-virus relationships in domestic and wild animals. Here we review the current gaps in wild animal and environmental surveillance and the current understanding of genetic signatures in potentially pandemic strains.
Url:
DOI: 10.1016/j.meegid.2013.02.020
PubMed: 23541413
PubMed Central: 3685205
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PMC:3685205Le document en format XML
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<author><name sortKey="Hill, Nichola" sort="Hill, Nichola" uniqKey="Hill N" first="Nichola" last="Hill">Nichola Hill</name>
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<author><name sortKey="Hussein, Islam T M" sort="Hussein, Islam T M" uniqKey="Hussein I" first="Islam T. M." last="Hussein">Islam T. M. Hussein</name>
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<front><div type="abstract" xml:lang="en"><p id="P1">Continuing outbreaks of pathogenic (H5N1) and pandemic (SOIVH1N1) influenza have underscored the need to understand the origin, characteristics, and evolution of novel influenza A virus (IAV) variants that pose a threat to human health. In the last 4–5 years, focus has been placed on the organization of large-scale surveillance programs to examine the phylogenetics of avian influenza virus (AIV) and host-virus relationships in domestic and wild animals. Here we review the current gaps in wild animal and environmental surveillance and the current understanding of genetic signatures in potentially pandemic strains.</p>
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<journal-id journal-id-type="nlm-ta">Infect Genet Evol</journal-id>
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Massachusetts Institute of Technology, Cambridge, MA</aff>
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Mystic Aquarium, a division of Sea Research Foundation, Mystic, CT</aff>
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<volume>17</volume>
<fpage>162</fpage>
<lpage>187</lpage>
<permissions><copyright-statement>© 2013 Elsevier B.V. All rights reserved.</copyright-statement>
<copyright-year>2013</copyright-year>
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<abstract><p id="P1">Continuing outbreaks of pathogenic (H5N1) and pandemic (SOIVH1N1) influenza have underscored the need to understand the origin, characteristics, and evolution of novel influenza A virus (IAV) variants that pose a threat to human health. In the last 4–5 years, focus has been placed on the organization of large-scale surveillance programs to examine the phylogenetics of avian influenza virus (AIV) and host-virus relationships in domestic and wild animals. Here we review the current gaps in wild animal and environmental surveillance and the current understanding of genetic signatures in potentially pandemic strains.</p>
</abstract>
<funding-group><award-group><funding-source country="United States">National Institute of Allergy and Infectious Diseases Extramural Activities : NIAID</funding-source>
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