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<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">Clinical Features and Outcome of 65 Laboratory Confirmed Cases of H1N1 in Muscat, Sultanate of Oman</title>
<author>
<name sortKey="Pajankar, Sumant" sort="Pajankar, Sumant" uniqKey="Pajankar S" first="Sumant" last="Pajankar">Sumant Pajankar</name>
</author>
<author>
<name sortKey="Al Qassabi, Salim Said" sort="Al Qassabi, Salim Said" uniqKey="Al Qassabi S" first="Salim Said" last="Al Qassabi">Salim Said Al Qassabi</name>
</author>
<author>
<name sortKey="Al Harthi, Saud Mohamed" sort="Al Harthi, Saud Mohamed" uniqKey="Al Harthi S" first="Saud Mohamed" last="Al Harthi">Saud Mohamed Al Harthi</name>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PMC</idno>
<idno type="pmid">22811768</idno>
<idno type="pmc">3394368</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394368</idno>
<idno type="RBID">PMC:3394368</idno>
<idno type="doi">10.5001/omj.2012.46</idno>
<date when="2012">2012</date>
<idno type="wicri:Area/Pmc/Corpus">000734</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000734</idno>
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<analytic>
<title xml:lang="en" level="a" type="main">Clinical Features and Outcome of 65 Laboratory Confirmed Cases of H1N1 in Muscat, Sultanate of Oman</title>
<author>
<name sortKey="Pajankar, Sumant" sort="Pajankar, Sumant" uniqKey="Pajankar S" first="Sumant" last="Pajankar">Sumant Pajankar</name>
</author>
<author>
<name sortKey="Al Qassabi, Salim Said" sort="Al Qassabi, Salim Said" uniqKey="Al Qassabi S" first="Salim Said" last="Al Qassabi">Salim Said Al Qassabi</name>
</author>
<author>
<name sortKey="Al Harthi, Saud Mohamed" sort="Al Harthi, Saud Mohamed" uniqKey="Al Harthi S" first="Saud Mohamed" last="Al Harthi">Saud Mohamed Al Harthi</name>
</author>
</analytic>
<series>
<title level="j">Oman Medical Journal</title>
<idno type="ISSN">1999-768X</idno>
<idno type="eISSN">2070-5204</idno>
<imprint>
<date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
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<profileDesc>
<textClass></textClass>
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<front>
<div type="abstract" xml:lang="en">
<sec>
<title>Objectives</title>
<p>Responding to Pandemic Influenza A (H1N1) virus alert in 2009, Ministry of Health (MoH), Sultanate Of Oman arranged task force to deal with the emergency. MOH published articles in newspapers, prepared guidelines and hospitals were assigned to admit patients of H1N1. All the patients suspected of H1N1 were admitted and isolated as per the guidelines. This report describes clinical features and outcomes of 65 laboratory confirmed cases of H1N1 in Muscat, Sultanate of Oman.</p>
</sec>
<sec>
<title>Methods</title>
<p>From July to October 2009, 101 cases suspected of suffering from Pandemic Influenza A (H1N1) virus were admitted and isolated in Al Nahdha Hospital in Muscat. All the patients on admission were tested for H1N1, by real time reverse transcriptase polymerase chain reaction (RT-PCR). Immediately on admission, all of them were treated with Oseltamivir and antibiotics.</p>
</sec>
<sec>
<title>Results</title>
<p>Of the 65 confirmed cases of H1N1, 53.84% were males. Age of patients varied from 14 to 60 years, while 53.7% were aged between 31 to 55 years. Results showed that 70.8% had underlying co-morbidity; among which diabetes mellitus and respiratory illness were common. The most common presenting symptoms were fever (95%) and cough (94%). Also, 20% of the patients had leucopenia and 10.8% leucocytosis. Deranged LFT was observed in 26 (42.6%) of cases while 14 (21.5%) had hypokalemia. One patient (0.01%) with underlying severe co-morbidity died. Two patients (3.1%) had ARDS (Acute Respiratory Distress Syndrome); both recovered. Radiological infiltration was documented in 84.6% of cases, with lower zone involvement as the common finding. Hospital stay was between 1 to 12 days, 49.2% of patients were discharged within 3 days.</p>
</sec>
<sec>
<title>Conclusion</title>
<p>Mainly adult population was affected during this epidemic. H1N1 infection can lead to severe illness. Incidence of H1N1 was higher in patients with underlying co-morbidity. Timely intervention and administration of Oseltamivir may need to be modified.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Oman Med J</journal-id>
<journal-id journal-id-type="iso-abbrev">Oman Med J</journal-id>
<journal-id journal-id-type="publisher-id">OMJ</journal-id>
<journal-title-group>
<journal-title>Oman Medical Journal</journal-title>
</journal-title-group>
<issn pub-type="ppub">1999-768X</issn>
<issn pub-type="epub">2070-5204</issn>
<publisher>
<publisher-name>OMJ</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">22811768</article-id>
<article-id pub-id-type="pmc">3394368</article-id>
<article-id pub-id-type="publisher-id">OMJ-D-11-00139</article-id>
<article-id pub-id-type="doi">10.5001/omj.2012.46</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Original Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Clinical Features and Outcome of 65 Laboratory Confirmed Cases of H1N1 in Muscat, Sultanate of Oman</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Pajankar</surname>
<given-names>Sumant</given-names>
</name>
<xref ref-type="corresp" rid="cor1">*</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Al Qassabi</surname>
<given-names>Salim Said</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Al Harthi</surname>
<given-names>Saud Mohamed</given-names>
</name>
</contrib>
<aff id="aff1">Department of Medicine, Al Nahdha Hospital, Ministry of Health, P.O Box: 937 PIN 112, Ruwi, Muscat, Sultanate of Oman.</aff>
</contrib-group>
<author-notes>
<corresp id="cor1">
<label>*</label>
Address correspondence and reprints request to: Sumant Pajankar, Department of Medicine, Al Nahdha Hospital, Ministry of Health, P.O Box: 937 PIN 112, Ruwi, Muscat, Sultanate of Oman. E-mail:
<email xlink:href="sumantp@omantel.net.om">sumantp@omantel.net.om</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub">
<month>5</month>
<year>2012</year>
</pub-date>
<volume>27</volume>
<issue>3</issue>
<fpage seq="b">201</fpage>
<lpage>206</lpage>
<history>
<date date-type="received">
<day>30</day>
<month>12</month>
<year>2011</year>
</date>
<date date-type="accepted">
<day>04</day>
<month>2</month>
<year>2012</year>
</date>
</history>
<permissions>
<copyright-year>2012</copyright-year>
<copyright-holder>Oman Medical Specialty Board</copyright-holder>
</permissions>
<abstract>
<sec>
<title>Objectives</title>
<p>Responding to Pandemic Influenza A (H1N1) virus alert in 2009, Ministry of Health (MoH), Sultanate Of Oman arranged task force to deal with the emergency. MOH published articles in newspapers, prepared guidelines and hospitals were assigned to admit patients of H1N1. All the patients suspected of H1N1 were admitted and isolated as per the guidelines. This report describes clinical features and outcomes of 65 laboratory confirmed cases of H1N1 in Muscat, Sultanate of Oman.</p>
</sec>
<sec>
<title>Methods</title>
<p>From July to October 2009, 101 cases suspected of suffering from Pandemic Influenza A (H1N1) virus were admitted and isolated in Al Nahdha Hospital in Muscat. All the patients on admission were tested for H1N1, by real time reverse transcriptase polymerase chain reaction (RT-PCR). Immediately on admission, all of them were treated with Oseltamivir and antibiotics.</p>
</sec>
<sec>
<title>Results</title>
<p>Of the 65 confirmed cases of H1N1, 53.84% were males. Age of patients varied from 14 to 60 years, while 53.7% were aged between 31 to 55 years. Results showed that 70.8% had underlying co-morbidity; among which diabetes mellitus and respiratory illness were common. The most common presenting symptoms were fever (95%) and cough (94%). Also, 20% of the patients had leucopenia and 10.8% leucocytosis. Deranged LFT was observed in 26 (42.6%) of cases while 14 (21.5%) had hypokalemia. One patient (0.01%) with underlying severe co-morbidity died. Two patients (3.1%) had ARDS (Acute Respiratory Distress Syndrome); both recovered. Radiological infiltration was documented in 84.6% of cases, with lower zone involvement as the common finding. Hospital stay was between 1 to 12 days, 49.2% of patients were discharged within 3 days.</p>
</sec>
<sec>
<title>Conclusion</title>
<p>Mainly adult population was affected during this epidemic. H1N1 infection can lead to severe illness. Incidence of H1N1 was higher in patients with underlying co-morbidity. Timely intervention and administration of Oseltamivir may need to be modified.</p>
</sec>
</abstract>
<kwd-group kwd-group-type="author">
<title>Keywords: </title>
<kwd>Pandemic Influenza A</kwd>
<kwd>H1N1</kwd>
<kwd>Muscat</kwd>
<kwd>Sultanate of Oman</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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