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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Impact of Influenza A(H1N1)pdm09 Virus on Circulation Dynamics of Seasonal Influenza Strains in Kenya</title><author><name sortKey="Majanja, Janet" sort="Majanja, Janet" uniqKey="Majanja J" first="Janet" last="Majanja">Janet Majanja</name></author><author><name sortKey="Njoroge, Rose N" sort="Njoroge, Rose N" uniqKey="Njoroge R" first="Rose N." last="Njoroge">Rose N. Njoroge</name></author><author><name sortKey="Achilla, Rachel" sort="Achilla, Rachel" uniqKey="Achilla R" first="Rachel" last="Achilla">Rachel Achilla</name></author><author><name sortKey="Wurapa, Eyako K" sort="Wurapa, Eyako K" uniqKey="Wurapa E" first="Eyako K." last="Wurapa">Eyako K. Wurapa</name></author><author><name sortKey="Wadegu, Meshack" sort="Wadegu, Meshack" uniqKey="Wadegu M" first="Meshack" last="Wadegu">Meshack Wadegu</name></author><author><name sortKey="Mukunzi, Silvanos" sort="Mukunzi, Silvanos" uniqKey="Mukunzi S" first="Silvanos" last="Mukunzi">Silvanos Mukunzi</name></author><author><name sortKey="Mwangi, Josephat" sort="Mwangi, Josephat" uniqKey="Mwangi J" first="Josephat" last="Mwangi">Josephat Mwangi</name></author><author><name sortKey="Njiri, James" sort="Njiri, James" uniqKey="Njiri J" first="James" last="Njiri">James Njiri</name></author><author><name sortKey="Gachara, George" sort="Gachara, George" uniqKey="Gachara G" first="George" last="Gachara">George Gachara</name></author><author><name sortKey="Bulimo, Wallace" sort="Bulimo, Wallace" uniqKey="Bulimo W" first="Wallace" last="Bulimo">Wallace Bulimo</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23458953</idno><idno type="pmc">3752763</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752763</idno><idno type="RBID">PMC:3752763</idno><idno type="doi">10.4269/ajtmh.12-0147</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">000606</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000606</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Impact of Influenza A(H1N1)pdm09 Virus on Circulation Dynamics of Seasonal Influenza Strains in Kenya</title><author><name sortKey="Majanja, Janet" sort="Majanja, Janet" uniqKey="Majanja J" first="Janet" last="Majanja">Janet Majanja</name></author><author><name sortKey="Njoroge, Rose N" sort="Njoroge, Rose N" uniqKey="Njoroge R" first="Rose N." last="Njoroge">Rose N. Njoroge</name></author><author><name sortKey="Achilla, Rachel" sort="Achilla, Rachel" uniqKey="Achilla R" first="Rachel" last="Achilla">Rachel Achilla</name></author><author><name sortKey="Wurapa, Eyako K" sort="Wurapa, Eyako K" uniqKey="Wurapa E" first="Eyako K." last="Wurapa">Eyako K. Wurapa</name></author><author><name sortKey="Wadegu, Meshack" sort="Wadegu, Meshack" uniqKey="Wadegu M" first="Meshack" last="Wadegu">Meshack Wadegu</name></author><author><name sortKey="Mukunzi, Silvanos" sort="Mukunzi, Silvanos" uniqKey="Mukunzi S" first="Silvanos" last="Mukunzi">Silvanos Mukunzi</name></author><author><name sortKey="Mwangi, Josephat" sort="Mwangi, Josephat" uniqKey="Mwangi J" first="Josephat" last="Mwangi">Josephat Mwangi</name></author><author><name sortKey="Njiri, James" sort="Njiri, James" uniqKey="Njiri J" first="James" last="Njiri">James Njiri</name></author><author><name sortKey="Gachara, George" sort="Gachara, George" uniqKey="Gachara G" first="George" last="Gachara">George Gachara</name></author><author><name sortKey="Bulimo, Wallace" sort="Bulimo, Wallace" uniqKey="Bulimo W" first="Wallace" last="Bulimo">Wallace Bulimo</name></author></analytic><series><title level="j">The American Journal of Tropical Medicine and Hygiene</title><idno type="ISSN">0002-9637</idno><idno type="eISSN">1476-1645</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>We describe virus variations from patients with influenza-like illness before and after the appearance of influenza A(H1N1)pdm09 in Kenya during January 2008–July 2011. A total of 11,592 nasopharyngeal swabs were collected from consenting patients. Seasonal influenza B, A/H1N1, A/H3N2, A/H5N1, and influenza A(H1N1)pdm09 viruses were detected by real-time reverse transcription–polymerase chain reaction. Of patients enrolled, 2073 (17.9%) had influenza. A total of 1,524 (73.4%) of 2,073 samples were positive for influenza A virus and 549 (26.6%) were positive for influenza B virus. Influenza B virus predominated in 2008 and seasonal A(H1N1) virus predominated in the first half of 2009. Influenza A(H1N1)pdm09 virus predominated in the second half of 2009. Influenza A/H3N2 virus predominated in 2010, and co-circulation of influenza A(H1N1)pdm09 virus and influenza B virus predominated the first half of 2011. The reduction and displacement of seasonal A(H1N1) virus was the most obvious effect of the arrival of influenza A(H1N1)pdm09 virus. The decision of the World Health Organization to replace seasonal A(H1N1) virus with the pandemic virus strain for the southern hemisphere vaccine was appropriate for Kenya.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Am J Trop Med Hyg</journal-id><journal-id journal-id-type="iso-abbrev">Am. J. Trop. Med. Hyg</journal-id><journal-id journal-id-type="publisher-id">tpmd</journal-id><journal-title-group><journal-title>The American Journal of Tropical Medicine and Hygiene</journal-title></journal-title-group><issn pub-type="ppub">0002-9637</issn><issn pub-type="epub">1476-1645</issn><publisher><publisher-name>The American Society of Tropical Medicine and Hygiene</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">23458953</article-id><article-id pub-id-type="pmc">3752763</article-id><article-id pub-id-type="doi">10.4269/ajtmh.12-0147</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Impact of Influenza A(H1N1)pdm09 Virus on Circulation Dynamics of Seasonal Influenza Strains in Kenya</article-title><alt-title alt-title-type="left-running-head">MAJANJA AND OTHERS</alt-title><alt-title alt-title-type="right-running-head">IMPACT OF A(H1N1)PDM09 VIRUS ON INFLUENZA VIRUS STRAINS IN KENYA</alt-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Majanja</surname><given-names>Janet</given-names></name></contrib><contrib contrib-type="author"><name><surname>Njoroge</surname><given-names>Rose N.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Achilla</surname><given-names>Rachel</given-names></name></contrib><contrib contrib-type="author"><name><surname>Wurapa</surname><given-names>Eyako K.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Wadegu</surname><given-names>Meshack</given-names></name></contrib><contrib contrib-type="author"><name><surname>Mukunzi</surname><given-names>Silvanos</given-names></name></contrib><contrib contrib-type="author"><name><surname>Mwangi</surname><given-names>Josephat</given-names></name></contrib><contrib contrib-type="author"><name><surname>Njiri</surname><given-names>James</given-names></name></contrib><contrib contrib-type="author"><name><surname>Gachara</surname><given-names>George</given-names></name></contrib><contrib contrib-type="author"><name><surname>Bulimo</surname><given-names>Wallace</given-names></name><xref ref-type="corresp" rid="COR1">*</xref></contrib></contrib-group><aff id="AFF1">U.S. Army Medical Research Unit, Kenya, Nairobi, Kenya; Department of Medical Laboratory Sciences, Kenyatta University, Nairobi, Kenya</aff><author-notes><corresp id="COR1">*Address correspondence to Wallace Bulimo, Department of Emerging Infectious Diseases, U.S. Army Medical Research Unit–Kenya, U.S. Embassy, PO Box 606-00621, Village Market, Nairobi, Kenya. E-mail: <email>wallace.bulimo@usamru-k.org</email></corresp></author-notes><pub-date pub-type="ppub"><day>01</day><month>5</month><year>2013</year></pub-date><volume>88</volume><issue>5</issue><fpage>940</fpage><lpage>945</lpage><history><date date-type="received"><day>06</day><month>3</month><year>2012</year></date><date date-type="accepted"><day>13</day><month>12</month><year>2012</year></date></history><permissions><copyright-statement>©The American Society of Tropical Medicine and Hygiene</copyright-statement><copyright-year>2013</copyright-year></permissions><abstract><p>We describe virus variations from patients with influenza-like illness before and after the appearance of influenza A(H1N1)pdm09 in Kenya during January 2008–July 2011. A total of 11,592 nasopharyngeal swabs were collected from consenting patients. Seasonal influenza B, A/H1N1, A/H3N2, A/H5N1, and influenza A(H1N1)pdm09 viruses were detected by real-time reverse transcription–polymerase chain reaction. Of patients enrolled, 2073 (17.9%) had influenza. A total of 1,524 (73.4%) of 2,073 samples were positive for influenza A virus and 549 (26.6%) were positive for influenza B virus. Influenza B virus predominated in 2008 and seasonal A(H1N1) virus predominated in the first half of 2009. Influenza A(H1N1)pdm09 virus predominated in the second half of 2009. Influenza A/H3N2 virus predominated in 2010, and co-circulation of influenza A(H1N1)pdm09 virus and influenza B virus predominated the first half of 2011. The reduction and displacement of seasonal A(H1N1) virus was the most obvious effect of the arrival of influenza A(H1N1)pdm09 virus. The decision of the World Health Organization to replace seasonal A(H1N1) virus with the pandemic virus strain for the southern hemisphere vaccine was appropriate for Kenya.</p></abstract></article-meta><notes notes-type="disclaimer"><p>Disclaimer: The views expressed in this article are those of the authors and should not be construed to represent the position of the United States Department of the Army or Department of Defense or the U.S. Government. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.</p></notes></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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