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<title xml:lang="en">Emergence and pandemic potential of swine-origin H1N1 influenza virus</title>
<author>
<name sortKey="Neumann, Gabriele" sort="Neumann, Gabriele" uniqKey="Neumann G" first="Gabriele" last="Neumann">Gabriele Neumann</name>
<affiliation>
<nlm:aff id="A1">Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, WI, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Noda, Takeshi" sort="Noda, Takeshi" uniqKey="Noda T" first="Takeshi" last="Noda">Takeshi Noda</name>
<affiliation>
<nlm:aff id="A2">International Research Center for Infectious Diseases, University of Tokyo, Tokyo, Japan</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Kawaoka, Yoshihiro" sort="Kawaoka, Yoshihiro" uniqKey="Kawaoka Y" first="Yoshihiro" last="Kawaoka">Yoshihiro Kawaoka</name>
<affiliation>
<nlm:aff id="A1">Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, WI, USA</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="A2">International Research Center for Infectious Diseases, University of Tokyo, Tokyo, Japan</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="A3">Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, Japan</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="A4">ERATO Infection-Induced Host Responses Project, Japan Science and Technology Agency, Saitama, Japan.</nlm:aff>
</affiliation>
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<idno type="wicri:source">PMC</idno>
<idno type="pmid">19525932</idno>
<idno type="pmc">2873852</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873852</idno>
<idno type="RBID">PMC:2873852</idno>
<idno type="doi">10.1038/nature08157</idno>
<date when="2009">2009</date>
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<title xml:lang="en" level="a" type="main">Emergence and pandemic potential of swine-origin H1N1 influenza virus</title>
<author>
<name sortKey="Neumann, Gabriele" sort="Neumann, Gabriele" uniqKey="Neumann G" first="Gabriele" last="Neumann">Gabriele Neumann</name>
<affiliation>
<nlm:aff id="A1">Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, WI, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Noda, Takeshi" sort="Noda, Takeshi" uniqKey="Noda T" first="Takeshi" last="Noda">Takeshi Noda</name>
<affiliation>
<nlm:aff id="A2">International Research Center for Infectious Diseases, University of Tokyo, Tokyo, Japan</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Kawaoka, Yoshihiro" sort="Kawaoka, Yoshihiro" uniqKey="Kawaoka Y" first="Yoshihiro" last="Kawaoka">Yoshihiro Kawaoka</name>
<affiliation>
<nlm:aff id="A1">Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, WI, USA</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="A2">International Research Center for Infectious Diseases, University of Tokyo, Tokyo, Japan</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="A3">Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, Japan</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="A4">ERATO Infection-Induced Host Responses Project, Japan Science and Technology Agency, Saitama, Japan.</nlm:aff>
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<title level="j">Nature</title>
<idno type="ISSN">0028-0836</idno>
<idno type="eISSN">1476-4687</idno>
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<div type="abstract" xml:lang="en">
<p id="P1">Influenza viruses cause annual epidemics and occasional pandemics that have claimed the lives of millions. The emergence of novel strains will continue to pose challenges to the public health and scientific communities. A prime example is the recent emergence of swine-origin H1N1 viruses that have transmitted to and spread among humans, resulting in outbreaks internationally. Efforts to control these outbreaks and real-time monitoring of the evolution of this virus should provide us with invaluable information to direct infectious disease control programs and to improve understanding of the factors that determine viral pathogenicity and/or transmissibility.</p>
</div>
</front>
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<pmc article-type="research-article" xml:lang="EN">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
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<journal-meta>
<journal-id journal-id-type="nlm-journal-id">0410462</journal-id>
<journal-id journal-id-type="pubmed-jr-id">6011</journal-id>
<journal-id journal-id-type="nlm-ta">Nature</journal-id>
<journal-title>Nature</journal-title>
<issn pub-type="ppub">0028-0836</issn>
<issn pub-type="epub">1476-4687</issn>
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<article-meta>
<article-id pub-id-type="pmid">19525932</article-id>
<article-id pub-id-type="pmc">2873852</article-id>
<article-id pub-id-type="doi">10.1038/nature08157</article-id>
<article-id pub-id-type="manuscript">NIHMS181435</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Article</subject>
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<title-group>
<article-title>Emergence and pandemic potential of swine-origin H1N1 influenza virus</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Neumann</surname>
<given-names>Gabriele</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Noda</surname>
<given-names>Takeshi</given-names>
</name>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Kawaoka</surname>
<given-names>Yoshihiro</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
<xref ref-type="aff" rid="A2">2</xref>
<xref ref-type="aff" rid="A3">3</xref>
<xref ref-type="aff" rid="A4">4</xref>
</contrib>
</contrib-group>
<aff id="A1">
<label>1</label>
Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, WI, USA</aff>
<aff id="A2">
<label>2</label>
International Research Center for Infectious Diseases, University of Tokyo, Tokyo, Japan</aff>
<aff id="A3">
<label>3</label>
Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, Japan</aff>
<aff id="A4">
<label>4</label>
ERATO Infection-Induced Host Responses Project, Japan Science and Technology Agency, Saitama, Japan.</aff>
<pub-date pub-type="nihms-submitted">
<day>12</day>
<month>5</month>
<year>2010</year>
</pub-date>
<pub-date pub-type="ppub">
<day>18</day>
<month>6</month>
<year>2009</year>
</pub-date>
<pub-date pub-type="pmc-release">
<day>20</day>
<month>5</month>
<year>2010</year>
</pub-date>
<volume>459</volume>
<issue>7249</issue>
<fpage>931</fpage>
<lpage>939</lpage>
<abstract>
<p id="P1">Influenza viruses cause annual epidemics and occasional pandemics that have claimed the lives of millions. The emergence of novel strains will continue to pose challenges to the public health and scientific communities. A prime example is the recent emergence of swine-origin H1N1 viruses that have transmitted to and spread among humans, resulting in outbreaks internationally. Efforts to control these outbreaks and real-time monitoring of the evolution of this virus should provide us with invaluable information to direct infectious disease control programs and to improve understanding of the factors that determine viral pathogenicity and/or transmissibility.</p>
</abstract>
</article-meta>
</front>
</pmc>
</record>

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