H2N2V1, Pmc, Corpus, bibRecord, 0003740

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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Sequence Variation in a Newly Identified HLA-B35-Restricted Epitope in the Influenza A Virus Nucleoprotein Associated with Escape from Cytotoxic T Lymphocytes</title>
<author><name sortKey="Boon, A C M" sort="Boon, A C M" uniqKey="Boon A" first="A. C. M." last="Boon">A. C. M. Boon</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="De Mutsert, G" sort="De Mutsert, G" uniqKey="De Mutsert G" first="G." last="De Mutsert">G. De Mutsert</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Graus, Y M F" sort="Graus, Y M F" uniqKey="Graus Y" first="Y. M. F." last="Graus">Y. M. F. Graus</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Fouchier, R A M" sort="Fouchier, R A M" uniqKey="Fouchier R" first="R. A. M." last="Fouchier">R. A. M. Fouchier</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sintnicolaas, K" sort="Sintnicolaas, K" uniqKey="Sintnicolaas K" first="K." last="Sintnicolaas">K. Sintnicolaas</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Osterhaus, A D M E" sort="Osterhaus, A D M E" uniqKey="Osterhaus A" first="A. D. M. E." last="Osterhaus">A. D. M. E. Osterhaus</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rimmelzwaan, G F" sort="Rimmelzwaan, G F" uniqKey="Rimmelzwaan G" first="G. F." last="Rimmelzwaan">G. F. Rimmelzwaan</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">11836437</idno>
<idno type="pmc">153818</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153818</idno>
<idno type="RBID">PMC:153818</idno>
<date when="2002">2002</date>
<idno type="wicri:Area/Pmc/Corpus">000374</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000374</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Sequence Variation in a Newly Identified HLA-B35-Restricted Epitope in the Influenza A Virus Nucleoprotein Associated with Escape from Cytotoxic T Lymphocytes</title>
<author><name sortKey="Boon, A C M" sort="Boon, A C M" uniqKey="Boon A" first="A. C. M." last="Boon">A. C. M. Boon</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="De Mutsert, G" sort="De Mutsert, G" uniqKey="De Mutsert G" first="G." last="De Mutsert">G. De Mutsert</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Graus, Y M F" sort="Graus, Y M F" uniqKey="Graus Y" first="Y. M. F." last="Graus">Y. M. F. Graus</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Fouchier, R A M" sort="Fouchier, R A M" uniqKey="Fouchier R" first="R. A. M." last="Fouchier">R. A. M. Fouchier</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sintnicolaas, K" sort="Sintnicolaas, K" uniqKey="Sintnicolaas K" first="K." last="Sintnicolaas">K. Sintnicolaas</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Osterhaus, A D M E" sort="Osterhaus, A D M E" uniqKey="Osterhaus A" first="A. D. M. E." last="Osterhaus">A. D. M. E. Osterhaus</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rimmelzwaan, G F" sort="Rimmelzwaan, G F" uniqKey="Rimmelzwaan G" first="G. F." last="Rimmelzwaan">G. F. Rimmelzwaan</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of Virology</title>
<idno type="ISSN">0022-538X</idno>
<idno type="eISSN">1098-5514</idno>
<imprint><date when="2002">2002</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Here, we describe a new HLA-B*3501-restricted cytotoxic T lymphocyte (CTL) epitope in the influenza A virus (H3N2) nucleoprotein, which was found to exhibit a high degree of variation at nonanchor residues. The influenza virus variants emerged in chronological order, and CTLs directed against old variants failed to recognize more recent strains of influenza A virus, indicating an escape from CTL immunity.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
  <front><journal-meta><journal-id journal-id-type="nlm-ta">J Virol</journal-id>
<journal-id journal-id-type="publisher-id">jvi</journal-id>
<journal-title>Journal of Virology</journal-title>
<issn pub-type="ppub">0022-538X</issn>
<issn pub-type="epub">1098-5514</issn>
<publisher><publisher-name>American Society for Microbiology</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">11836437</article-id>
<article-id pub-id-type="pmc">153818</article-id>
<article-id pub-id-type="publisher-id">1881</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Virus-Cell Interactions</subject>
</subj-group>
</article-categories>
<title-group><article-title>Sequence Variation in a Newly Identified HLA-B35-Restricted Epitope in the Influenza A Virus Nucleoprotein Associated with Escape from Cytotoxic T Lymphocytes</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Boon</surname>
<given-names>A. C. M.</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>de Mutsert</surname>
<given-names>G.</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Graus</surname>
<given-names>Y. M. F.</given-names>
</name>
<xref ref-type="aff" rid="aff1">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Fouchier</surname>
<given-names>R. A. M.</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Sintnicolaas</surname>
<given-names>K.</given-names>
</name>
<xref ref-type="aff" rid="aff1">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Osterhaus</surname>
<given-names>A. D. M. E.</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rimmelzwaan</surname>
<given-names>G. F.</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="corresp" rid="cor1">*</xref>
</contrib>
</contrib-group>
<aff id="aff1">Institute of Virology, Erasmus University Rotterdam, 3015 GE Rotterdam,<label>1</label>
 Numico Research B. V., 6700 CA Wageningen,<label>2</label>
 Laboratory for Histocompatibility and Immunogenetics, Bloodbank Rotterdam, 3318 AS Dordrecht, The Netherlands<label>3</label>
</aff>
<author-notes><fn id="cor1"><label>*</label>
<p>Corresponding author. Mailing address: Institute of Virology, Erasmus University Rotterdam, Dr. Molewaterplein 50, 3015 GE Rotterdam, The Netherlands. Phone: 31-10-4088066. Fax: 31-10-4089485. E-mail: <email>rimmelzwaan@viro.fgg.eur.nl</email>
.</p>
</fn>
</author-notes>
<pub-date pub-type="ppub"><month>3</month>
<year>2002</year>
</pub-date>
<volume>76</volume>
<issue>5</issue>
<fpage>2567</fpage>
<lpage>2572</lpage>
<history><date date-type="received"><day>24</day>
<month>9</month>
<year>2001</year>
</date>
<date date-type="accepted"><day>28</day>
<month>11</month>
<year>2001</year>
</date>
</history>
<copyright-statement>Copyright © 2002, American Society for Microbiology</copyright-statement>
<copyright-year>2002</copyright-year>
<abstract><p>Here, we describe a new HLA-B*3501-restricted cytotoxic T lymphocyte (CTL) epitope in the influenza A virus (H3N2) nucleoprotein, which was found to exhibit a high degree of variation at nonanchor residues. The influenza virus variants emerged in chronological order, and CTLs directed against old variants failed to recognize more recent strains of influenza A virus, indicating an escape from CTL immunity.</p>
</abstract>
</article-meta>
</front>
</pmc>
</record>

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